JamesWilliardDennisMD

PubMed

• 2 citations
  Molecular and Metabolomic Investigation of Celecoxib Antiproliferative Activity in Mono-and Combination Therapy Against Breast Cancer Cell Models.
  Sanaa K. Bardaweel, Lina A. Dahabiyeh, Bushra M. Akileh, Dana D. Shalabi, Afnan K. AlHiary, Judy Pawling, James W. Dennis, Anas M. Abdel Rahman> ;Anti-Cancer Agents in Medicinal Chemistry. 2021 Sep 9
• 14 citations
  Association of a Marker of N-Acetylglucosamine With Progressive Multiple Sclerosis and Neurodegeneration.
  Michael Sy, Judith Bellmann-Strobl, Barbara L. Newton, Judy Pawling, Hanna Zimmermann, Zhaoxia Yu, Claudia Chien, Jan Dörr, Jens Th Wuerfel, James W. Dennis, Friedeman...> ;JAMA Neurology. 2021 Jul 1
• 25 citations
  Glioma stem cells invasive phenotype at optimal stiffness is driven by MGAT5 dependent mechanosensing.
  Emilie Marhuenda, Christine Fabre, Cunjie Zhang, Marta Martin-Fernandez, Thomas Iskratsch, Ali Saleh, Luc Bauchet, Julien Cambedouzou, Jean-Philippe Hugnot, Hugues Duf...> ;Journal of Experimental & Clinical Cancer Research. 2021 Apr 24
• 22 citations
  Mevalonate Pathway Inhibition Slows Breast Cancer Metastasis via Reduced N-glycosylation Abundance and Branching
  Rosemary Yu, Joseph Longo, Jenna E. van Leeuwen, Cunjie Zhang, Emily Branchard, Mohamad Elbaz, David W. Cescon, Richard R. Drake, James W. Dennis, Linda Z. Penn> ;Cancer Research. 2021 May 15
• 3 citations
  N-acetylglucosamine drives myelination by triggering oligodendrocyte precursor cell differentiation.
  Michael Sy, Alexander U Brandt, Sung-Uk Lee, Barbara L Newton, Judy Pawling, Autreen Golzar, Anas M A Rahman, Zhaoxia Yu, Graham Cooper, Michael Scheel, Friedemann Pau...> ;The Journal of Biological Chemistry. 2020 Dec 18
• 36 citations
  The GATOR-Rag GTPase pathway inhibits mTORC1 activation by lysosome-derived amino acids.
  Geoffrey G. Hesketh, Fotini Papazotos, Judy Pawling, Dushyandi Rajendran, James D.R. Knight, Sebastien Martinez, Mikko Taipale, Daniel Schramek, James W. Dennis, Anne-...> ;Science. 2020 Oct 16
• 250 citations
  A Genetic Map of the Response to DNA Damage in Human Cells
  Michele Olivieri, Tiffany Cho, Alejandro Álvarez-Quilón, Kejiao Li, Matthew J. Schellenberg, Michal Zimmermann, Nicole Hustedt, Silvia Emma Rossi, Salomé Adam, Henriqu...> ;Cell. 2020 Jul 23
• 50 citations
  Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
  Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy Hin Yan Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj...> ;Nature Metabolism. 2020 Jun 1
• 8 citations
  Caveolin-1 Y14 phosphorylation suppresses tumor growth while promoting invasion.
  Bharat H. Joshi, Judy Pawling, Jay Shankar, Karina Pacholczyk, Yohan Kim, Wynn Tran, Fanrui Meng, Anas M. Abdel Rahman, Leonard J. Foster, Hon S. Leong, James W. Denni...> ;Oncotarget. 2019 Nov 19
• 11 citations
  Increasing cell permeability of N-acetylglucosamine via 6-acetylation enhances capacity to suppress T-helper 1 (TH1)/TH17 responses and autoimmunity.
  Sung-Uk Lee, Carey F. Li, Christie-Lynn Mortales, Judy Pawling, James W. Dennis, Ani Grigorian, Michael A. Demetriou> ;Plos One. 2019 Mar 26
• 4 citations
  Identification of unique characteristics and the management of blunt traumatic aortic injuries occurring at unusual locations in the descending thoracic aorta.
  Michel J. Sabra, James W. Dennis, Jon Christian Allmon, Shiva Gautam, Joseph H. Habib> ;Journal of Vascular Surgery. 2019 Jan 1
• 20 citations
  N-linked glycosylation modulates the immunogenicity of recombinant human factor VIII in hemophilia A mice
  Jesse D. Lai, Laura L. Swystun, Dominique Cartier, Kate Nesbitt, Cunjie Zhang, Christine Hough, James W. Dennis, David Lillicrap> ;Haematologica. 2018 Nov 1
• Gallbladder Rupture and Acute Thoracic Aortic Disruption after Blunt Trauma.
  Dustin Price, Lori A. Gurien, James W. Dennis, Brian K. Yorkgitis> ;The American Surgeon. 2018 Sep 1
• 3 citations
  The UBR-1 ubiquitin ligase regulates glutamate metabolism to generate coordinated motor pattern in Caenorhabditis elegans.
  Jyothsna Chitturi, Wesley Hung, Anas M. Abdel Rahman, Min Wu, Maria A. Lim, John A. Calarco, Renee Baran, Xun Huang, James W. Dennis, Mei Zhen> ;Plos Genetics. 2018 Apr 12
• 1 citations
  Novel application of an old technique: the use of external to internal carotid artery transposition in trauma.
  Abbie Jensen, James W. Dennis, Jon Christian Allmon, Joseph H. Habib, David Skarupa> ;Trauma Surgery & Acute Care Open. 2018 Apr 1
• Reassessing the utility of CT angiograms in penetrating injuries to the extremities.
  Lori A. Gurien, Andrew J. Kerwin, Brian K. Yorkgitis, John Renkosik, J. Christian Allmon, Joseph H. Habib, James W. Dennis> ;Surgery. 2017 Nov 1
• 6 citations
  The directed migration of gonadal distal tip cells in Caenorhabditis elegans requires NGAT-1, a ß1,4-N-acetylgalactosaminyltransferase enzyme.
  Joseph Veyhl, Robert J. Dunn, Wendy L. Johnston, Alexa Bennett, Lijia W. Zhang, James W. Dennis, Harry Schachter, Joseph G. Culotti> ;Plos One. 2017 Aug 17
• 5 citations
  C. elegans SUP-46, an HNRNPM family RNA-binding protein that prevents paternally-mediated epigenetic sterility
  Wendy L. Johnston, Aldis Krizus, Arun K. Ramani, Wade H. Dunham, Ji-Young Youn, Andrew G. Fraser, Anne-Claude Gingras, James W. Dennis> ;BMC Biology. 2017 Jul 17
• 4 citations
  N-acetylglucosamine: more than a silent partner in insulin resistance
  Geoffrey G. Hesketh, James W. Dennis> ;Glycobiology. 2017 Jul 1
• 101 citations
  Plk4 Promotes Cancer Invasion and Metastasis through Arp2/3 Complex Regulation of the Actin Cytoskeleton.
  Karineh Kazazian, Christopher D. Go, Hannah Wu, Olga Brashavitskaya, Roland S.Z. Xu, James W. Dennis, Anne-Claude Gingras, Carol J. Swallow> ;Cancer Research. 2017 Jan 15
• 10 citations
  Mgat5 modulates the effect of early life stress on adult behavior and physical health in mice.
  Laura A. Feldcamp, Jean-Sebastien Doucet, Judy Pawling, Marc P. Fadel, Paul J. Fletcher, Robert G. Maunder, James W. Dennis, Albert H.C. Wong> ;Behavioural Brain Research. 2016 Oct 1
• 69 citations
  PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia
  Robert S. Banh, Caterina Iorio, Richard Marcotte, Yang Xu, Dan Cojocari, Anas M. Abdel Rahman, Judy Pawling, Wei Zhang, Ankit Sinha, Christopher M. Rose, Marta Isasa, ...> ;Nature Cell Biology. 2016 Jul 1
• 70 citations
  Metabolic Reprogramming by Hexosamine Biosynthetic and Golgi N-Glycan Branching Pathways.
  Michael Ryczko, Judy Pawling, Rui Chen, Anas M. Abdel Rahman, Kevin Yau, Julia K. Copeland, Cunjie Zhang, Anu Surendra, David S. Guttman, Daniel Figeys, James W. Dennis> ;Scientific Reports. 2016 Mar 14
• 17 citations
  Many Light Touches Convey the Message
  James W. Dennis> ;Trends in Biochemical Sciences. 2015 Nov 1
• 207 citations
  The galectin lattice at a glance.
  Ivan R. Nabi, Jay Shankar, James W. Dennis> ;Journal of Cell Science. 2015 Jul 1
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