JamesWarrenEvansMD

PubMed

• 46 citations
  Homologous Recombination Is the Principal Pathway for the Repair of DNA Damage Induced by Tirapazamine in Mammalian Cells
  James W. Evans, Sophia B. Chernikova, Lisa A. Kachnic, Judit P. Banath, Olivier Sordet, Yvette M. Delahoussaye, Alejandro D. Treszezamsky, Brian H. Chon, Zhihui Feng, ...> ;Cancer Research. 2008 Jan 1
• 49 citations
  Metabolism of tirapazamine by multiple reductases in the nucleus.
  Yvette M. Delahoussaye, James W. Evans, J. Martin Brown> ;Biochemical Pharmacology. 2001 Nov 1
• 23 citations
  Mitochondrial dysfunction after aerobic exposure to the hypoxic cytotoxin tirapazamine
  Bradly G. Wouters, Yvette M. Delahoussaye, James W. Evans, Geoffrey W. Birrell, Mary Jo Dorie, Jingli Wang, Dhara MacDermed, Roland K. Chiu, J. Martin Brown> ;Cancer Research. 2001 Jan 1
• 57 citations
  Cisplatin anti-tumour potentiation by tirapazamine results from a hypoxia-dependent cellular sensitization to cisplatin
  Mary S. Kovacs, D J Hocking, James W. Evans, Bronwyn G. Siim, Bradly G. Wouters, J M Brown> ;British Journal of Cancer. 1999 Jun 1
• 45 citations
  Tirapazamine Is Metabolized to Its DNA-damaging Radical by Intranuclear Enzymes
  James W. Evans, K Yudoh, Yvette M. Delahoussaye, J M Brown> ;Cancer Research. 1998 May 15
• 42 citations
  Adaptation of human tumor cells to tirapazamine under aerobic conditions: Implications of increased antioxidant enzyme activity to mechanism of aerobic cytotoxicity
  James H. Elwell, Bronwyn G. Siim, James W. Evans, J. Martin Brown> ;Biochemical Pharmacology. 1997 Jul 15
• 5 citations
  Stable Translocations Detected by Fluorescence in Situ Hybridization: A Rapid Surrogate End Point to Evaluate the Efficacy of a Potentiator of Tumor Response to Radiot...
  Mary S. Kovacs, Kazuo Yudoh, James W. Evans, Douglas B. Menke, J. Martin Brown> ;Cancer Research. 1997 Feb 15
• 41 citations
  Induction and repair of chromosome aberrations in scid cells measured by premature chromosome condensation.
  James W. Evans, Xiehe Liu, Cordula U. Kirchgessner, J. Martin Brown> ;Radiation Research. 1996 Jan 1
• 47 citations
  Prediction of human cell radiosensitivity: Comparison of clonogenic assay with chromosome aberrations scored using premature chromosome condensation with fluorescence ...
  Keisuke Sasai, James W. Evans, Mary S. Kovacs, J. Martin Brown> ;International Journal of Radiation Oncology, Biology, Physics. 1994 Dec 1
• 76 citations
  Radiation-Induced Damage, Repair and Exchange Formation in Different Chromosomes of Human Fibroblasts Determined by Fluorescence In Situ Hybridization
  Mary S. Kovacs, James W. Evans, I. M. Johnstone, J. M. Brown> ;Radiation Research. 1994 Jan 1
• 68 citations
  Chromosomal radiosensitivity at intrachromosomal telomeric sites.
  Luis Alvarez, James W. Evans, Rebecah Wilks, Joe N. Lucas, J. Martin Brown, Amato J. Giaccia> ;Genes, Chromosomes & Cancer. 1993 Sep 1
• 35 citations
  Mechanism of chromosome exchange formation in human fibroblasts: Insights from “chromosome painting”
  J. M. Brown, James W. Evans, Mary S. Kovacs> ;Environmental and Molecular Mutagenesis. 1993 Jan 1
• 15 citations
  Analysis of restriction enzyme-induced chromosomal aberrations by fluorescence in situ hybridization.
  Elma Abella Columna, Amato J. Giaccia, James W. Evans, Barbara L. Yates, William F. Morgan> ;Environmental and Molecular Mutagenesis. 1993 Jan 1
• 17 citations
  The Hypersensitivity of the Chinese Hamster Ovary Variant BL-10 to Bleomycin Killing Is Due to a Lack of Glutathione S-Transferase-α Activity
  Amato J. Giaccia, A.D. Lewis, Nicholas C. Denko, A. Cholon, James W. Evans, Charles A. Waldren, Thomas D. Stamato, Janice M. Brown> ;Cancer Research. 1991 Aug 15
• 12 citations
  Loss of the intrinsic heat resistance of human cells and changes in Mr 70,000 heat shock protein expression in human x hamster hybrids.
  Robin L. Anderson, Kathy J. Fong, Tim Gabriele, Pablo Lavagnini, George M. Hahn, James W. Evans, Charles A. Waldren, Thomas D. Stamato, Amato J. Giaccia> ;Cancer Research. 1991 May 15
• 39 citations
  The use of fluorescence in situ hybridisation combined with premature chromosome condensation for the identification of chromosome damage.
  James W. Evans, J.A. Chang, Amato J. Giaccia, D. Pinkel, Janice M. Brown> ;British Journal of Cancer. 1991 Apr 1
• 9 citations
  Use of fluorescent in situ hybridization to detect chromosomal rearrangements in somatic cell hybrids.
  Amato J. Giaccia, James W. Evans, J.M. Brown> ;Genes, Chromosomes & Cancer. 1990 Sep 1
• 12 citations
  Radiosensitization by hypoxic pretreatment with misonidazole: an interaction of damage at the DNA level.
  Yvonne C. Taylor, James W. Evans, J. Martin Brown> ;Radiation Research. 1987 Mar 1
• 41 citations
  Mechanism of Sensitization of Chinese Hamster Ovary Cells to Melphalan by Hypoxic Treatment with Misonidazole
  Yvonne C. Taylor, James W. Evans, J. Martin Brown> ;Cancer Research. 1983 Jul 1
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