JamesAubrieFlemingMD

PubMed

• 101 citations
  Mechanism of Action and Clinical Application of Tafamidis in Hereditary Transthyretin Amyloidosis
  Teresa Coelho, Giampaolo Merlini, Christine Bulawa, James Fleming, Daniel P. Judge, Jeffery W. Kelly, Mathew S. Maurer, Violaine Planté-Bordeneuve, Richard Labaudinièr...> ;Neurology and Therapy. 2016 Feb 19
• Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade.
  Bulawa CE, Connelly S, Devit M, Wang L, Weigel C, Fleming JA, Packman J, Powers ET, Wiseman RL, Foss TR, Wilson IA, Kelly JW, Labaudinière R> ;Proc. Natl. Acad. Sci. U.S.A.. 2012-06-12
• Systematic exploration of essential yeast gene function with temperature-sensitive mutants.
  Li, Z., Vizeacoumar, F.J., Bahr, S., Li, J., Warringer, J., Vizeacoumar, F.S., Min, R., Vandersluis, B., Bellay, J., Devit, M., Fleming, J.A., Stephens, A., Haase, J.,...> ;Nat Biotechnol. 2011 Apr
• Biological characterization of MLN944: a potent DNA binding agent.
  Sappal, D.S., McClendon, A.K., Fleming, J.A., Thoroddsen, V., Connolly, K., Reimer, C., Blackman, R.K., Bulawa, C.E., Osheroff, N., Charlton, P., Rudolph-Owen, L.A.> ;Mol Cancer Ther. 2004 Jan
• 138 citations
  Deficiencies of GM-CSF and Interferon γ Link Inflammation and Cancer
  Thomas Enzler, Silke Gillessen, John P. Manis, David O. Ferguson, James Fleming, Frederick W. Alt, Martin C. Mihm, Glenn Dranoff> ;The Journal of Experimental Medicine. 2003 May 5
• Complementary whole-genome technologies reveal the cellular response to proteasome inhibition by PS-341.
  Fleming, J.A., Lightcap, E.S., Sadis, S., Thoroddsen, V., Bulawa, C.E., Blackman, R.K.> ;Proc Natl Acad Sci U S A. 2002 Feb 5
• Modulation of tubulin polypeptide ratios by the yeast protein Pac10p.
  Alvarez P, Smith A, Fleming J, Solomon F> ;Genetics. 1998-06-01
• Ferritin: isolation of aluminum-ferritin complex from brain.
  Fleming J, Joshi JG> ;Proc. Natl. Acad. Sci. U.S.A.. 1987-11-01
• Defective DNA repair and increased genomic instability in Artemis-deficient murine cells.
  Rooney, S., Alt, F. W., Lombard, D., Whitlow, S., Eckersdorff, M., Fleming, J., Fugmann, S., Ferguson, D. O., Schatz, D. G., Sekiguchi, J.> ;J Exp Med. 2003 Mar 3
• Function of tubulin binding proteins in vivo.
  Fleming, J. A., Vega, L. R., Solomon, F.> ;Genetics. 2000 Sep
• Detection of compounds that rescue Rab1-synuclein toxicity.
  Fleming, J., Outeiro, T. F., Slack, M., Lindquist, S. L., Bulawa, C. E.> ;Methods Enzymol. 2008
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