JamesHardwickIIIMDFACC

PubMed

• 27 citations
  Combining CDK4/6 inhibition with taxanes enhances anti-tumor efficacy by sustained impairment of pRB-E2F pathways in squamous cell lung cancer
  Joan Cao, Zhou Zhu, Hui Wang, Timothy Nichols, Goldie Y. L. Lui, Shibing Deng, Paul A. Rejto, Todd VanArsdale, James S. Hardwick, Scott L. Weinrich, Ping Wei> ;Oncogene. 2019 Jan 30
• 15 citations
  Predicting Response to Histone Deacetylase Inhibitors Using High-Throughput Genomics
  Paul Geeleher, Andrey Loboda, Divya Lenkala, Fan Wang, Bonnie LaCroix, Sanja Karovic, Jacqueline Wang, Michael Nebozhyn, Michael Chisamore, James S. Hardwick, Michael ...> ;Journal of the National Cancer Institute. 2015 Nov 1
• 1339 citations
  Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes
  Razvan Cristescu, Jeeyun Lee, Michael Nebozhyn, Kyoung-Mee Kim, Jason C. Ting, Swee Seong Wong, Jiangang Liu, Yong Gang Yue, Jian Wang, Kun Yu, Xiang S. Ye, In-Gu Do, ...> ;Nature Medicine. 2015 May 1
• 24 citations
  Genome-wide identification of RNA editing in hepatocellular carcinoma.
  Lin Kang, Xiaoqiao Liu, Zhoulin Gong, Hancheng Zheng, Jun Wang, Yingrui Li, Huanming Yang, James S. Hardwick, Hongyue Dai, Ronnie T.P. Poon, Nikki P. Lee, Mao Mao, Zhi...> ;Genomics. 2015 Feb 1
• 135 citations
  Genomic landscape and genetic heterogeneity in gastric adenocarcinoma revealed by whole-genome sequencing.
  Swee Seong Wong, Kyoung-Mee Kim, Jason C. Ting, Kun Yu, Jake Fu, Shawn Liu, Razvan Cristescu, Michael Nebozhyn, Lara Gong, Yong Gang Yue, Jian Wang, Chen Ronghua, Andr...> ;Nature Communications. 2014 Nov 19
• 98 citations
  Downregulation of MHC-I Expression Is Prevalent but Reversible in Merkel Cell Carcinoma
  Kelly G. Paulson, Andrew Tegeder, Christoph Willmes, Jayasri G. Iyer, Olga K. Afanasiev, David Schrama, Shinichi Koba, Renee Thibodeau, Kotaro Nagase, William T. Simon...> ;Cancer Immunology Research. 2014 Aug 12
• 389 citations
  Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma
  Zhengyan Kan, Hancheng Zheng, Xiao Liu, Shuyu Li, Thomas D. Barber, Zhuolin Gong, Huan Gao, Ke Hao, Melinda D. Willard, Jiangchun Xu, Robert Hauptschein, Paul A. Rejto...> ;Genome Research. 2013 Sep 1
• 42 citations
  Phase I Trial of Vorinostat Combined With Bortezomib for the Treatment of Relapsing and/or Refractory Multiple Myeloma
  Donna M. Weber, Thorsten Graef, Mohamad A. Hussein, Ronald Sobecks, Gary J. Schiller, Lisa Lupinacci, James S. Hardwick, Sundar Jagannath> ;Clinical Lymphoma, Myeloma & Leukemia. 2012 Oct 1
• 666 citations
  Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma
  Wing-Kin Sung, Hancheng Zheng, Shuyu Li, Ronghua Chen, Xiao Liu, Yingrui Li, Nikki P. Lee, Wah Heng Lee, Pramila N. Ariyaratne, Chandana Tennakoon, Fabianus Hendriyan ...> ;Nature Genetics. 2012 Jul 1
• 125 citations
  A 4-Gene Signature Predicts Survival of Patients With Resected Adenocarcinoma of the Esophagus, Junction, and Gastric Cardia
  Christopher J. Peters, Jonathan Rees, Richard H. Hardwick, James S. Hardwick, Sarah L. Vowler, Chin-Ann Johnny Ong, Chunsheng Zhang, Vicki Save, Maria O'Donovan, Doris...> ;Gastroenterology. 2010 Dec 1
• 59 citations
  Down‐regulation of the Notch pathway mediated by a γ‐secretase inhibitor induces anti‐tumour effects in mouse models of T‐cell leukaemia
  Jennifer Tammam, Christopher Ware, Clay L. Efferson, Jennifer O'Neil, Sudhir Rao, Xianlu Qu, J Gorenstein, Minilik Angagaw, Han Sang Kim, Candia M. Kenific, Kaiko Kuni...> ;British Journal of Pharmacology. 2009 Nov 1
• 265 citations
  Phase II Trial of Vorinostat in Recurrent Glioblastoma Multiforme: A North Central Cancer Treatment Group Study
  Evanthia Galanis, Kurt A. Jaeckle, Matthew J. Maurer, Joel M. Reid, Matthew M. Ames, James S. Hardwick, John F. Reilly, Andrey Loboda, Michael Nebozhyn, Valeria R. Fan...> ;Journal of Clinical Oncology. 2009 Apr 20
• 110 citations
  Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells.
  Sudhir Rao, Jennifer O'Neil, Cole Liberator, James S. Hardwick, Xudong Dai, Theresa Zhang, Edyta Tyminski, Jing Yuan, Nancy E. Kohl, Victoria M. Richon, Lex H.T. Van d...> ;Cancer Research. 2009 Apr 1
• 458 citations
  Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes
  Guillermo Garcia-Manero, H. Yang, Carlos E. Bueso-Ramos, Alessandra Ferrajoli, Jorge E. Cortes, William G. Wierda, Stefan Faderl, Charles Koller, Gail Morris, Gary L. ...> ;Blood. 2008 Feb 1
• 537 citations
  FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors
  Jennifer O'Neil, Jonathan E. Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James S. Hardwick, Markus Welcker, Jules P.P. Meijerink, Rob Pieters,...> ;The Journal of Experimental Medicine. 2007 Aug 6
• Join now to see all