JamesJasonHothMD

General Surgery • Winston Salem, NC

Trauma Surgery & Surgical Critical Care

Associate Professor, Surgical Sciences, Bowman Gray School of Medicine of Wake Forest Univ

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Office
Medical Center Blvd
Winston Salem, NC 27157
Phone+1 336-716-2255

Fax+1 336-716-6637
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Education & Training

University of Louisville School of MedicineFellowship, Surgical Critical Care, 2001 - 2003
Wake Forest University School of MedicineResidency, Surgery, 1996 - 2001
LSU School of Medicine in ShreveportClass of 1996

Certifications & Licensure

NC State Medical License 1996 - 2024
KY State Medical License 2001 - 2004
American Board of Surgery Surgery
American Board of Surgery Surgical Critical Care

Awards, Honors, & Recognition

Fellow (FACS) American College of Surgeons

Clinical Trials

LIPS-A: Lung Injury Prevention Study With Aspirin Start of enrollment: 2012 Jan 01
Completed
Phase 2

Publications & Presentations

PubMed

Reply to Letter to the Editor: Eliminating the Benzos: A Benzodiazepine-Sparing Approach to Preventing and Treating Alcohol Withdrawal Syndrome.
Mary Alyce McCullough, Preston R Miller 3rd, Tamriage Martin, Kristin A Rebo, Gregory R Stettler, Robert Shayn Martin, Elizabeth H Shilling, James J Hoth, Andrew M Nunn> ;The Journal of Trauma and Acute Care Surgery. 2024 Feb 19
5 citations
Professionalism of Admitting and Consulting Services and Trauma Patient Outcomes.
William O Cooper, Gerald B Hickson, Oscar D Guillamondegui, Jeremy W Cannon, Anthony G Charles, J Jason Hoth, Hasan B Alam, Areti Tillou, Frederick A Luchette, Dionne ...> ;Annals of Surgery. 2022 May 1
Sizing of airborne particles in an operating room.
Peter T. Tkacik, Jerry L. Dahlberg, James E. Johnson, James J. Hoth, Rebecca A. Szer, Samuel Hellman> ;Plos One. 2021 Apr 5
11 citations
Undertriage Despite Use of Geriatric-Specific Trauma Team Activation Guidelines : Who Are We Missing?
Matthew D. Painter, Franck Diaz-Garelli, Andrew M. Nunn, Preston R. Miller, Michael C. Chang, J. Jason Hoth> ;The American Surgeon. 2021 Mar 1
17 citations
SIRT1 Mediates Septic Cardiomyopathy in a Murine Model of Polymicrobial Sepsis.
Lane M. Smith, Barbara K. Yoza, J. Jason Hoth, Charles E. McCall, Vidula Vachharajani> ;Shock. 2020 Jul 1
4 citations
Antioxidant treatment after injury suppresses second hit immune priming.
J. Jason Hoth, Lane M. Smith, Cristina M. Furdui, Jonathan D. Wells, Barbara K. Yoza, Charles E. McCall> ;The Journal of Trauma and Acute Care Surgery. 2018 Aug 1
10 citations
Predicting Mortality and Independence at Discharge in the Aging Traumatic Brain Injury Population Using Data Available at Admission
Preston R. Miller, Michael C. Chang, J. Jason Hoth, Amy N. Hildreth, Stacey Q Wolfe, Jessica L. Gross, R. Shayn Martin, Jeffrey E Carter, J. Wayne Meredith, Ralph B. D...> ;Journal of the American College of Surgeons. 2017 Apr 1
220 citations
Sirtuins Link Inflammation and Metabolism.
Vidula Vachharajani, Tie Fu Liu, Xianfeng Wang, J. Jason Hoth, Barbara K. Yoza, Charles E. McCall> ;Journal of Immunology Research. 2016 Jan 20
9 citations
Subcapsular hematoma in blunt splenic injury: A significant predictor of failure of nonoperative management.
Joseph Martin Lopez, Patrick W. McGonagill, Jessica L. Gross, J. Jason Hoth, Michael C. Chang, Karen Parker, Jay A. Requarth, Preston R. Miller> ;The Journal of Trauma and Acute Care Surgery. 2015 Dec 1
12 citations
SIRT1 mediates a primed response to immune challenge after traumatic lung injury.
Lane M. Smith, Jonathan D. Wells, Vidula Vachharajani, Barbara K. Yoza, Charles E. McCall, J. Jason Hoth> ;The Journal of Trauma and Acute Care Surgery. 2015 May 1
69 citations
Predicting risk of postoperative lung injury in high-risk surgical patients: a multicenter cohort study.
Daryl J. Kor, Ravi K. Lingineni, Ognjen Gajic, Pauline K. Park, James M. Blum, Peter C. Hou, J. Jason Hoth, Harry L. Anderson, Ednan K. Bajwa, Raquel R. Bartz, Adebola...> ;Anesthesiology. 2014 May 1
92 citations
Prospective Trial of Angiography and Embolization for All Grade III to V Blunt Splenic Injuries: Nonoperative Management Success Rate Is Significantly Improved
Preston R. Miller, Michael C. Chang, J. Jason Hoth, Nathan T. Mowery, Amy N. Hildreth, R. Shayn Martin, James H. Holmes, J. Wayne Meredith, Jay A. Requarth> ;Journal of the American College of Surgeons. 2014 Apr 1
35 citations
Complement mediates a primed inflammatory response after traumatic lung injury.
J. Jason Hoth, Jonathan D. Wells, Sarah Jones, Barbara K. Yoza, Charles E. McCall> ;The Journal of Trauma and Acute Care Surgery. 2014 Mar 1
A grim picture, indeed.
J. Jason Hoth> ;Critical Care Medicine. 2013 Mar 1
11 citations
Investigation of pulmonary contusion extent and its correlation to crash, occupant, and injury characteristics in motor vehicle crashes.
Ashley A. Weaver, Kerry A. Danelson, Elizabeth G. Armstrong, J. Jason Hoth, Joel D. Stitzel> ;Accident; Analysis and Prevention. 2013 Jan 1
17 citations
Locally Derived versus Guideline-Based Approach to Treatment of Hospital-Acquired Pneumonia in the Trauma Intensive Care Unit
Robert D. Becher, J. Jason Hoth, Jerry J. Rebo, Jennifer L. Kendall, Preston R. Miller> ;Surgical Infections. 2012 Dec 26
27 citations
An innovative approach to predict the development of adult respiratory distress syndrome in patients with blunt trauma.
Robert D. Becher, Alexander L. Colonna, Toby M. Enniss, Ashley A. Weaver, Daniel K. Crane, R. Shayn Martin, Nathan T. Mowery, Preston R. Miller, Joel D. Stitzel, J. Ja...> ;The Journal of Trauma and Acute Care Surgery. 2012 Nov 1
Does Acute Physiology and Chronic Health Evaluation II provide a valid metric to directly compare disease severity in trauma versus surgical intensive care unit patients
Robert D. Becher, Michael C. Chang, J. Jason Hoth, Kendall Jl, Beard Hr, Preston R. Miller> ;The American Surgeon. 2012 Nov 1
7 citations
Prehospital amiodarone may increase the incidence of acute respiratory distress syndrome among patients at risk
Lioudmila V. Karnatovskaia, Emir Festic, Ognjen Gajic, Rickey E. Carter, Augustine S. Lee, Adil Ahmed, Michael Malinchoc, Daryl J. Kor, Bekele Afessa, Rodrigo Cartin-C...> ;Journal of Critical Care. 2012 Oct 1
55 citations
Systemic inflammation worsens outcomes in emergency surgical patients.
Robert D. Becher, J. Jason Hoth, Preston R. Miller, J. Wayne Meredith, Michael C. Chang> ;The Journal of Trauma and Acute Care Surgery. 2012 May 1
12 citations
Innate immune response to pulmonary contusion: identification of cell type-specific inflammatory responses.
J. Jason Hoth, Jonathan D. Wells, Barbara K. Yoza, Charles E. McCall> ;Shock. 2012 Apr 1
28 citations
Creation and Implementation of an Emergency General Surgery Registry Modeled after the National Trauma Data Bank
Robert D. Becher, J. Wayne Meredith, Michael C. Chang, J. Jason Hoth, H. Randall Beard, Preston R. Miller> ;Journal of the American College of Surgeons. 2012 Feb 1
32 citations
Type I interferon signaling regulates the composition of inflammatory infiltrates upon infection with Listeria monocytogenes
Kristina L. Brzoza-Lewis, J. Jason Hoth, Elizabeth M. Hiltbold> ;Cellular Immunology. 2012 Jan 1
14 citations
Multidrug-resistant pathogens and pneumonia: comparing the trauma and surgical intensive care units.
Robert D. Becher, J. Jason Hoth, Lucas P. Neff, Jerry J. Rebo, R. Shayn Martin, Preston R. Miller> ;Surgical Infections. 2011 Aug 22
2 citations
Design, Development, and Analysis of a Surrogate for Pulmonary Injury Prediction
Kerry A. Danelson, F. Scott Gayzik, Amber Rath Stern, J. Jason Hoth, Joel D. Stitzel> ;Annals of Biomedical Engineering. 2011 Jul 22
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