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James Jakub, MD, General Surgery, Jacksonville, FL

James W. Jakub MD

Breast, Melanoma, Surgical Oncology (Other than Breast)


Professor of Surgery Division of Surgical Oncology

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  • 4500 San Pablo Rd SJacksonville, FL 32224

  • Phone+1 904-953-2000

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Summary

  • Dr Jakub is a high volume surgical oncologist, with a primary focus on breast cancer and melanoma.

    Dr Jakub has been an early adopter and championed dissemination of a number of novel surgical innovations. He has been recognized by receiving the Mayo Clinic Innovation in Education Award and Outstanding Course Directors for our Radioguided Breast Surgery course which has trained over 500 individuals; many of them adopting this new procedure into clinical practice. He is a leader in disseminating the novel technique of minimally invasive inguinal lymph node dissection for melanoma, for which he lead a 12 site multi-institutional trial melanoma. Dr Jakub is currently PI on a prospective trial investigating the role of axillary reverse mapping and lympho-venous bypass at the time of axillary lymph node dissection with the goal of preventing one of the greatest fears patients have of the operation, lymphedema. He is actively exploring the role of robotic breast surgery. He is the course director for a Mayo Clinic CME course Innovation, Disruptive Technologies and Early Adopters in Breast Cancer Care: Tomorrows Technologies Today as well as a co-course director for the highly successful Mayo Clinic Annual Practical Course in Dermoscopy & Update on Malignant Melanoma.

    He feels very fortunate to be working in a physician lead organization with a large clinical volume, significant institutional infrastructure and a collaborative team approach whose primary value is the needs of the patients come first.
  • Breast cancer innovations saving lives

    Dr. James Jakub, a breast surgeon at Mayo Clinic's Jacoby Center for Breast Health, joins us to talk to us about the latest innovations in breast surgery.

Clinical Expertise

  • Sentinel lymph node biopsy, Melanoma, Breast cancer, Lymphadenectomy

Education & Training

  • H. Lee Moffitt Cancer Center and Research Institute
    H. Lee Moffitt Cancer Center and Research InstituteFellowship, Breast Surgical Oncology, 2001 - 2002
  • Prisma Health/University of South Carolina SOM Columbia (Columbia)
    Prisma Health/University of South Carolina SOM Columbia (Columbia)Residency, Surgery, 1995 - 2000
  • MCP-Hahnemann College of Medicine
    MCP-Hahnemann College of MedicineClass of 1995

Certifications & Licensure

  • FL State Medical License
    FL State Medical License 2002 - 2028
  • MN State Medical License
    MN State Medical License 2008 - 2027
  • SC State Medical License
    SC State Medical License 1996 - 2003
  • Surgery
    American Board of Surgery Surgery

Awards, Honors, & Recognition

  • Outstanding Course Directors Award - 15th Annual Practical Course in Dermoscopy and Update on Malignant Melanoma Mayo Clinic, 2021
  • CMS Meaningful Use Stage 1 Certification Centricity Enterprise (CE), GE Healthcare, 2014
  • CMS Meaningful Use Stage 1 Certification Centricity Enterprise, GE Healthcare, 2014

Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Decreasing Use of Axillary Dissection in Node-Positive Breast Cancer Patients Treated with Neoadjuvant Chemotherapy  
    James W Jakub, Amy C Degnim, Tina J Hieken, Judy C Boughey, Annals of Surgical Oncology
  • Breast Cancer Litigation in the 21st Century  
    James W Jakub, Martin D Zielinski, Brittany L Murphy, Annals of Surgical Oncology

Lectures

  • Radioactive Seed Localized Breast Surgery 
    Mayo School of Continuous Professional Development, Rochester, Minnesota - 7/19/2013
  • Radioactive Seed Localized Breast Surgery 
    Mayo School of Continuous Professional Development, Rochester, Minnesota - 7/20/2012

Press Mentions

  • Mayo Clinic Leads 4 Decades of Advances in Breast Cancer Care
    Mayo Clinic Leads 4 Decades of Advances in Breast Cancer CareOctober 2nd, 2025
  • Embracing Precision Medicine for Advanced Melanoma with Tumor-Infiltrating Lymphocyte (TIL) Therapy
    Embracing Precision Medicine for Advanced Melanoma with Tumor-Infiltrating Lymphocyte (TIL) TherapySeptember 23rd, 2025
  • Breast Cancer Surgery Program in Jacksonville
    Breast Cancer Surgery Program in JacksonvilleAugust 14th, 2025

Committees

  • Corporate Relations Committee, American Society of Breast Surgeons 2022 - Present
  • Board Member, Mayo Clinic eTumor Steering Committee 2020 - Present
  • Program Committee Member, Western Surgical Association 2019 - Present
  • Editorial Board Member - Melanoma Section, Annals of Surgical Oncology 2018 - Present
  • Editorial Board Member - Melanoma Section, Journal of Surgical Oncology 2016 - Present

Professional Memberships

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