JamesLeeKneplerMD

Pulmonology • Tucson, AZ

Critical Care Medicine, Interventional Pulmonology, Sleep Medicine, Thoracic Oncology

Professor of Medicine, University Ariz College of Medicine

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Office
1501 N Campbell Ave
Tucson, AZ 85724
Phone+1 520-626-6114

Fax+1 513-475-7327
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Education & Training

Indiana University School of MedicineFellowship, Pulmonary Disease and Critical Care Medicine, 1998 - 2001
Ohio State University HospitalResidency, Internal Medicine, 1994 - 1997
Ohio State University College of MedicineClass of 1994

Certifications & Licensure

AZ State Medical License 2011 - 2026
IN State Medical License 1999 - 2025
CO State Medical License 2020 - 2025
NV State Medical License 2020 - 2025
OH State Medical License 1995 - 2024
NE State Medical License 2020 - 2024
WY State Medical License 2020 - 2024
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

Top Doctors:Arizona State Castle Connolly, 2013

Clinical Trials

Sleep Intervention During Acute Lung Injury Start of enrollment: 2009 Aug 01
Completed
Phase 4
A Prospective Observational Study of Biopredictors of Bronchial Thermoplasty Response in Patients With Severe Refractory Asthma (BTR Study) Start of enrollment: 2010 Aug 01
Completed

Publications & Presentations

PubMed

Cell-free DNA methylation analysis as a marker of malignancy in pleural fluid.
Billie Bixby, Lukas Vrba, Jyoti Lenka, Marc M Oshiro, George S Watts, Trina Hughes, Heidi Erickson, Madhav Chopra, James L Knepler, Kenneth S Knox, Lisa Jarnagin, Raed...> ;Scientific Reports. 2024 Feb 5
Cell-Free DNA Methylation Analysis as a Marker of Malignancy in Pleural Fluid.
Billie Bixby, Lukas Vrba, Jyoti Lenka, Marc Oshiro, George S Watts, Trina Hughes, Heidi Erickson, Madhav Chopra, James L Knepler, Kenneth S Knox, Lisa Jarnagin, Raed A...> ;Research Square. 2023 Oct 9
13 citations
SARS-CoV-2 Rapid Antigen Testing of Symptomatic and Asymptomatic Individuals on the University of Arizona Campus
David T. Harris, Michael Badowski, Brandon Jernigan, Ryan Sprissler, Taylor Edwards, Randall P. Cohen, Stephen Paul, Nirav Merchant, Craig Weinkauf, Christian Bime, He...> ;Biomedicines. 2021 May 12
231 citations
Orthogonal SARS-CoV-2 Serological Assays Enable Surveillance of Low-Prevalence Communities and Reveal Durable Humoral Immunity.
Tyler J. Ripperger, Jennifer L. Uhrlaub, Makiko Watanabe, Rachel O.L. Wong, Yvonne Castaneda, Hannah A. Pizzato, Mallory R. Thompson, Christine M. Bradshaw, Craig Wein...> ;Immunity. 2020 Nov 17
18 citations
Detection, prevalence, and duration of humoral responses to SARS-CoV-2 under conditions of limited population exposure.
Tyler J. Ripperger, Jennifer L. Uhrlaub, Makiko Watanabe, Rachel O.L. Wong, Yvonne Castaneda, Hannah A. Pizzato, Mallory R. Thompson, Christine M. Bradshaw, Craig Wein...> ;Medrxiv. 2020 Aug 16
10 citations
Endobronchial Valves Therapy for Advanced Emphysema: A Meta-Analysis of Randomized Trials.
See Wei Low, Justin Z. Lee, Hem Desai, Chiu Hsieh Hsu, Afshin Sam, James Knepler> ;Journal of Bronchology & Interventional Pulmonology. 2019 Apr 1
11 citations
The Use of Extracorporeal Membrane Oxygenation in the Bronchoscopic Management of Critical Upper Airway Obstruction.
Bhupinder Natt, James Knepler, Toshinobu Kazui, Jarrod Mosier> ;Journal of Bronchology & Interventional Pulmonology. 2017 Jan 1
35 citations
The impact of a comprehensive airway management training program for pulmonary and critical care medicine fellows. A three-year experience.
Jarrod Mosier, Joshua Malo, John C. Sakles, Cameron Hypes, Bhupinder Natt, Linda Snyder, James Knepler, John W. Bloom, Raj Joshi, Kenneth S. Knox> ;Annals of the American Thoracic Society. 2015 Apr 21
13 citations
Clinical Characteristics, Comorbidities, and Response to Treatment of Veterans With Obstructive Sleep Apnea, Cincinnati Veterans Affairs Medical Center, 2005-2007
Pamela Samson, Kenneth R. Casey, James Knepler, Ralph J. Panos> ;Preventing Chronic Disease. 2012 Jan 26
5 citations
The mean green popsicle: using cryotherapy to remove aspirated foreign bodies.
Joseph C. Seaman, James L. Knepler, Karen A. Bauer, Mitchell C. Rashkin> ;Journal of Bronchology & Interventional Pulmonology. 2010 Oct 1
70 citations
Peroxynitrite causes endothelial cell monolayer barrier dysfunction
James L. Knepler, Loui N. Taher, Mahesh P. Gupta, Carolyn E. Patterson, Fred M. Pavalko, Michael D. Ober, C. Michael Hart> ;American Journal of Physiology. Cell Physiology. 2001 Sep 1
Bronchoscopic diagnosis of infectious and inflammatory pulmonary disease.
Knepler, J. L., Mathur, P. N.> ;Chest Surg Clin N Am. 2001 Nov
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Press Mentions

UA Researchers Say Shelter-in-Place Order Could Avert 'Catastrophe' in Arizona HospitalsNovember 30th, 2020

Hospital Affiliations

Banner - University Medical Center TucsonTucson, Arizona
Banner - University Medical Center SouthTucson, Arizona
Tucson VA Medical CenterTucson, Arizona