JamesDLuketichMD

Minimally Invasive Thoracic Surgery, Thoracic Surgical Oncology, Cardiovascular Surgery

Henry T. Bahnson Endowed Professor of Surgery Chairman, Emeritus Department of Cardiothoracic Surgery University of Pittsburgh Medical Center

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Office
5200 Centre Ave
Pittsburgh, PA 15232
Phone+1 412-647-7555

Fax+1 412-647-2850
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Education & Training

Cleveland Clinic FoundationFellowship, Thoracic Surgery, 1994 - 1995
Memorial Sloan Kettering Cancer CenterFellowship, Thoracic Surgery, 1993 - 1995
New York Presbyterian Hospital (Cornell Campus)Fellowship, Thoracic Surgery, 1993 - 1995
University of Pennsylvania Health SystemResidency, Surgery, 1986 - 1993
MCP-Hahnemann College of MedicineClass of 1986

Certifications & Licensure

PA State Medical License 1988 - 2024
NY State Medical License 1993 - 1997
American Board of Thoracic Surgery Thoracic and Cardiac Surgery

Awards, Honors, & Recognition

Dean’s Award MCP, 1986
Fellow (FACS) American College of Surgeons

Clinical Trials

Esophagectomy in Treating Patients With High-Grade Dysplasia of the Esophagus or Stage I, Stage II, or Stage III Esophageal Cancer Start of enrollment: 2004 Jun 24
Completed
Phase 2
Microarray Analysis of Gene Expression in Idiopathic Pulmonary Fibrosis (IPF) Start of enrollment: 2001 Oct 01
Active, not recruiting
Outcomes After Esophagectomy With a Focus on Minimally Invasive Esophagectomy and Quality of Life Start of enrollment: 1999 May 01
Recruiting
Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux Disease Start of enrollment: 1999 Apr 01
Active, not recruiting
Esophageal Cancer Risk Registry Start of enrollment: 1999 Jun 01
Recruiting
Study of Outcomes of Radiofrequency Ablation of Lung Tumors Start of enrollment: 2003 Sep 01
Suspended
Detection of Genetic Markers of Lung Cancer Start of enrollment: 1996 Jun 01
Recruiting
CyberKnife Radiosurgical Treatment of Inoperable Early Stage Non-Small Cell Lung Cancer Start of enrollment: 2006 Apr 01
Unknown status
Phase 2
Radiosurgery for Patients With Oligometastatic Disease at Initial Presentation Start of enrollment: 2013 Jun 07
Terminated
Phase 2
Pyloroplasty Versus No Pyloroplasty in Patients Undergoing Esophagectomy Start of enrollment: 2018 Nov 27
Active, not recruiting
Not Applicable
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Publications & Presentations

PubMed

3 citations
Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells.
Feng Shan, Anthony R Cillo, Carly Cardello, Daniel Y Yuan, Sheryl R Kunning, Jian Cui, Caleb Lampenfeld, Asia M Williams, Alexandra P McDonough, Arjun Pennathur, James...> ;Science Immunology. 2023 Sep 15
2 citations
Carcinogen 4-Nitroquinoline Oxide (4-NQO) Induces Oncostatin-M (OSM) in Esophageal Cells.
Amitava Mukherjee, Michael W Epperly, Renee Fisher, Donna Shields, Wen Hou, Arjun Pennathur, James Luketich, Hong Wang, Joel S Greenberger> ;In Vivo. 2023 Mar 7
Evaluation of electromagnetic navigational bronchoscopic biopsy of lung lesions performed by a thoracic surgical service.
Tadeusz D Witek, Arjun Pennathur, Daniel Brynien, James D Luketich, Mark Scaife, David Azar, Matthew J Schuchert, William E Gooding, Omar Awais> ;Surgery. 2023 May 1
1 citations
Effects of Intraoperative Support Strategies on Endothelial Injury and Clinical Lung Transplant Outcomes.
Jenalee N Coster, Kentaro Noda, John P Ryan, Ernest G Chan, Masashi Furukawa, James D Luketich, Pablo G Sanchez> ;Seminars in Thoracic and Cardiovascular Surgery. 2023 Jan 28
1 citations
Oesophagectomy following noncurative endoscopic resection for oesophageal carcinoma: does interval matter?
Binhao Huang, Yangqing Deng, Zhichao Liu, Xiuzhi Zhu, Yuceng Su, Dantong Gu, Zhigang Li, Wentao Fang, Arjun Pennathur, James D Luketich, Jiaqing Xiang, Hezhong Chen, Q...> ;European Journal of Cardio-Thoracic Surgery. 2022 Dec 2
3 citations
A maladaptive pleural environment suppresses preexisting anti-tumor activity of pleural infiltrating T cells.
Vera S Donnenberg, James D Luketich, Ibrahim Sultan, John Lister, David L Bartlett, Sohini Ghosh, Albert D Donnenberg> ;Frontiers in Immunology. 2023 Jan 1
Single-center experience of ex vivo lung perfusion and subsequent lung transplantation.
Kentaro Noda, Ernest G Chan, Masashi Furukawa, John P Ryan, Sarah Clifford, James D Luketich, Pablo G Sanchez> ;Clinical Transplantation. 2023 Feb 1
Right middle lobe syndrome after upper lobectomy: Role of the bronchial angle.
Diane C Strollo, Vera S Donnenberg, Shobhit Madan, Pauline L Moran, James D Luketich, Manuel Villa Sanchez> ;Asian Cardiovascular & Thoracic Annals. 2023 Mar 1
Comparison of robotic-assisted minimally invasive esophagectomy versus minimally invasive esophagectomy: A propensity-matched study from a single high-volume institution.
Chigozirim N Ekeke, Gino M Kuiper, James D Luketich, Kristine M Ruppert, Susan J Copelli, Nicholas Baker, Ryan M Levy, Omar Awais, Neil A Christie, Rajeev Dhupar, Arju...> ;The Journal of Thoracic and Cardiovascular Surgery. 2023 Aug 1
1 citations
Colon Interposition for Esophageal Cancer.
Manuel Villa Sanchez, Evan T Alicuben, James D Luketich, Inderpal S Sarkaria> ;Thoracic Surgery Clinics. 2022 Nov 1
2 citations
Intraoperative Support for Primary Bilateral Lung Transplantation: A Propensity-Matched Analysis.
Ernest G Chan, Eric J Hyzny, Masashi Furukawa, John P Ryan, Kathirvel Subramaniam, Matthew R Morrell, Joseph Pilewski, James D Luketich, Pablo G Sanchez> ;Surgical Laparoscopy, Endoscopy & Percutaneous Techniques. 2023 Mar 1
2 citations
Robotic-assisted minimally invasive thymectomy for myasthenia gravis with thymoma.
Katherine W Su, James D Luketich, Inderpal S Sarkaria> ;JTCVS Techniques. 2022 Jun 1
1 citations
The effect of receiving an award from the American Association for Thoracic Surgery Foundation.
Edgar Aranda-Michel, James D Luketich, Rashmi Rao, Victor O Morell, George J Arnaoutakis, Arman Kilic, Courtenay Dunn-Lewis, Ibrahim Sultan> ;JTCVS Open. 2022 Jun 1
The Use of Extracorporeal Support to Rescue Patients With Acute Respiratory Distress Syndrome Following Thoracic Surgery.
Erin V Feeney, Ernest G Chan, Eric J Hyzny, Raj Ramanan, Holt Murray, James D Luketich, Pablo G Sanchez> ;ASAIO Journal. 2022 Dec 1
37 citations
Prospective Evaluation of Coronavirus Disease 2019 (COVID-19) Vaccine Responses Across a Broad Spectrum of Immunocompromising Conditions: the COVID-19 Vaccination in t...
Ghady Haidar, Mounzer Agha, Andrew Bilderback, Amy Lukanski, Kelsey Linstrum, Rachel Troyan, Scott Rothenberger, Deborah K McMahon, Melissa D Crandall, Michele D Sobol...> ;Clinical Infectious Diseases. 2022 Aug 24
4 citations
Localized Intra-Cavitary Therapy to Drive Systemic Anti-Tumor Immunity.
Vera S Donnenberg, Patrick L Wagner, James D Luketich, David L Bartlett, Albert D Donnenberg> ;Frontiers in Immunology. 2022 Jan 1
2 citations
Isoforms of Neuropilin-2 Denote Unique Tumor-Associated Macrophages in Breast Cancer.
Rajeev Dhupar, Katherine E Jones, Amy A Powers, Seth H Eisenberg, Kai Ding, Fangyuan Chen, Cecile Nasarre, Zhanpeng Cen, Yi-Nan Gong, Amanda C LaRue, Elizabeth S Yeh, ...> ;Frontiers in Immunology. 2022 Jan 1
The ideal approach for treatment of cT1N+ and cT2Nany esophageal cancer.: a NCDB analysis.
Binhao Huang, Ernest G Chan, Arjun Pennathur, James D Luketich, Jie Zhang> ;BMC Cancer. 2021 Dec 15
16 citations
Prevalence of intratumoral regulatory T cells expressing neuropilin-1 is associated with poorer outcomes in patients with cancer.
Christopher A Chuckran, Anthony R Cillo, Jessica Moskovitz, Abigail Overacre-Delgoffe, Ashwin S Somasundaram, Feng Shan, Grant C Magnon, Sheryl R Kunning, Irina Abecas...> ;Science Translational Medicine. 2021 Dec 8
18 citations
Definition and assessment of high risk in patients considered for lobectomy for stage I non–small cell lung cancer: The American Association for Thoracic Surgery exper...
Arjun Pennathur, Alessandro Brunelli, Gerard J. Criner, Homa Keshavarz, Peter J. Mazzone, Garrett Walsh, James D. Luketich, Michael Liptay, Q. Eileen Wafford, Sudish M...> ;The Journal of Thoracic and Cardiovascular Surgery. 2021 Dec 1
3 citations
Oncogenic Activity of Solute Carrier Family 45 Member 2 and Alpha-Methylacyl-Coenzyme A Racemase Gene Fusion Is Mediated by Mitogen-Activated Protein Kinase.
Ze-Hua Zuo, Yanping Yu, Baoguo Ren, Silvia Liu, Joel B. Nelson, Zhou Wang, Junyan Tao, Tirthadipa Pradhan-Sundd, Rohit Bhargava, George K. Michalopoulos, Qi Chen, Jun ...> ;Hepatology Communications. 2021 Sep 10
2 citations
Laparoscopic Repair of Giant Paraesophageal Hernia
Evan T. Alicuben, James D. Luketich, Ryan M. Levy> ;JTCVS Techniques. 2021 Aug 6
2 citations
Experimental respiratory exposure to putative Gulf War toxins promotes persistent alveolar macrophage recruitment and pulmonary inflammation.
Amy A. Powers, Katherine E. Jones, Seth H. Eisenberg, Lora H. Rigatti, John P. Ryan, James D. Luketich, Michael T. Lotze, Amanda C. LaRue, Rajeev Dhupar, Adam C. Soloff> ;Life Sciences. 2021 Jul 19
4 citations
Postprocedural Cognitive Load Measurement With Immediate Feedback to Guide Curriculum Development
Lauren V. Huckaby, Anthony R. Cyr, Robert Handzel, Eliza B. Littleton, James D. Luketich, Kenneth K. Lee, Rajeev Dhupar, Lawrence R. Crist> ;The Annals of Thoracic Surgery. 2021 Jun 29
8 citations
Heparanase inhibition preserves the endothelial glycocalyx in lung grafts and improves lung preservation and transplant outcomes.
Kentaro Noda, Brian J. Philips, Mark E. Snyder, Julie A. Phillippi, Mara Sullivan, Donna B. Stolz, Xi Ren, James D. Luketich, Pablo G. Sanchez> ;Scientific Reports. 2021 Jun 10
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Lectures

Masters of Minimally Invasive Thoracic Surgery
Duke University School of Medicine, Orlando, Florida - 9/19/2013
Masters of Minimally Invasive Thoracic Surgery
Duke University School of Medicine, Orlando, Florida - 9/21/2012

Press Mentions

Robotic Tracheobronchoplasty: Single-Patch Technique with Running SutureMay 8th, 2023
VATS Robotic Assisted Bilobectomy and Complex Bronchoplastic Reconstruction and Closure for Synchronous Endobronchial Carcinoid TumorsMay 17th, 2022
UPMC CEO Jeffrey Romoff's Salary Rises to $8.96 MillionJuly 10th, 2020
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Grant Support

Use Of Quantitative RT-PCR For Staging Esophageal CancerNational Cancer Institute2005–2009
Use Of Quantitative RT PCR For Staging Esophageal CancerNational Cancer Institute2001–2004