James Matthew Luther MD MSCI
Hypertension, Renovascular Medicine, Clinical Pharmacology
Associate Professor of Medicine and Pharmacology
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3601 21st Ave SNashville, TN 37232
Phone+1 615-322-3353
Fax+1 615-936-0605
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Summary
- Dr. James M. Luther is Associate Professor of medicine and pharmacology at Vanderbilt University School of Medicine in Nashville, Tennessee. The focus of his translational research program is to investigate the pathophysiologic links between hypertension and metabolic complications. His clinical focus in the Vanderbilt Hypertension Clinic is to evaluate and treat resistant and secondary hypertension. He is board certified in Medicine and Nephrology.
Dr. Luther received his MD degree from Vanderbilt School of Medicine, where he also completed training in Internal Medicine, Clinical Pharmacology, and Nephrology before joining the faculty in the Division of Clinical Pharmacology. He also received a Masters in Clinical Investigation program at Vanderbilt, and now serves as faculty in the program.
Education & Training
Vanderbilt Univ Med Ctr2007 - 2008- Vanderbilt Univ Med Ctr2005 - 2007
Vanderbilt University Medical CenterResidency, Internal Medicine, 2001 - 2004
Vanderbilt University School of MedicineClass of 2001
Certifications & Licensure
TN State Medical License 2003 - 2027
AL State Medical License 2020 - 2020
American Board of Internal Medicine Internal Medicine- American Board of Internal Medicine Nephrology
Clinical Trials
- Aldosterone and Glucose Homeostasis Start of enrollment: 2008 Sep 01
- Aldosterone and the Metabolic Syndrome Start of enrollment: 2010 Mar 01
- Endogenous Renin-Angiotensin-Aldosterone System and Glucose Metabolism Start of enrollment: 2013 Oct 01
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Publications & Presentations
PubMed
- Approaching Drug Choices and Challenges for the Management of Hypertension.Adam P Bress, James M Luther
Hypertension. 2025-10-01 - 26 citationsLorundrostat Efficacy and Safety in Patients with Uncontrolled Hypertension.Luke J Laffin, Branko Kopjar, Carrie Melgaard, Kathy Wolski, Jessica Ibbitson
The New England Journal of Medicine. 2025-05-08 - 5 citationsEpoxygenase Cyp2c44 Regulates Hepatic Lipid Metabolism and Insulin Signaling by Controlling FATP2 Localization and Activation of the DAG/PKCδ Axis.Kakali Ghoshal, James M Luther, Suman B Pakala, Sergei Chetyrkin, John R Falck
Diabetes... 2024-08-01
Books/Book Chapters
Press Mentions
What's Your Approach? MRAs and Chronic Kidney DiseaseJuly 30th, 2023- Diabetes Drug May Improve AsthmaFebruary 21st, 2023
- Medicare Reimbursement Policy for Ambulatory Blood Pressure Monitoring: A Qualitative Analysis of Public Comments to the Centers for Medicare and Medicaid ServicesDecember 1st, 2019
Grant Support
- Islet Cell and ST2 Axis Dysregulation in Post-Transplant Diabetes MellitusVANDERBILT UNIVERSITY MEDICAL CENTER2018–2025
- Endogenous Aldosterone and glucose metabolismNIH/NIDDK, NHLBI2013–Present
- Role of Eicosanoids in Renal FunctionNIH/NIDDK2009–Present
- Aldosterone And Glucose MetabolismNational Institute Of Diabetes And Digestive And Kidney Diseases2008–2011
Professional Memberships
- Member
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- American Federation for Medical Research - AFMRMember
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