James C Oates MD
Lupus & Related, Rheumatoid Arthritis & Related, Clinical Informatics
Professor of Medicine, Richard M. Silver Endowed Chair, Director of Rheumaotlogy and Immunology, Vice Chair for Research, Department of Medicine, Medical University of South Carolina.
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96 Jonathan Lucas StreetSuite 822, MSC 637Charleston, SC 29425
Phone+1 843-792-1991
Fax+1 843-792-7121
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Summary
- My general training is in immunology and autoimmunity, with specific expertise in lupus, lupus nephritis, endothelial dysfunction, biomarkers and predictors of lupus nephritis outcomes and atherosclerosis in lupus, and the role of reactive intermediates in lupus nephritis and atherosclerosis. I have maintained a translational research laboratory and have developed a clinical research program as an integral member of the Medical University of South Carolina Lupus Erythematosus (MUSCLE) clinical research group and the CCCR P30 leadership. I have conducted multiple investigator initiated clinical studies and commercial clinical trials.
I am the Director of the MUSC the NIAMS P30 Core Center for Clinical Research (CCCR) and Vice Chair for Research in the Department of Medicine. As the former Informatics Medical Director of Research and Reporting for the Medical University Hospital Authority, I was in charge of integration of clinical research processes into the electronic health record and governance of research data. Collaborations developed during the time of this Directorship have lead to projects on electronic phenotyping and prediction and outcome tools derived from medical record data.
Finally, I serve as Chair of the Division Directors Committee of the American College of Rheumatology. In this position, I collaborate with colleagues to address the most important issues facing division directors in our subspecialty.
Education & Training
Medical University of South CarolinaFellowship, Rheumatology, 1996 - 1997
Duke University HospitalFellowship, Rheumatology, 1994 - 1996- Duke University HospitalResidency, Internal Medicine, 1991 - 1994
Johns Hopkins University School of MedicineClass of 1991
Bates CollegeB.S., Chemistry, 1982 - 1986
Certifications & Licensure
SC State Medical License 1996 - 2027
NC State Medical License 1993 - 1998
American Board of Internal Medicine Rheumatology
Awards, Honors, & Recognition
- Member Americal Clinical and Climatological Association, 2018
- Member Henry Kunkel Society, 2018
- CMS Meaningful Use Stage 2 Certification Beacon Oncology 2014 Certified Module, Epic Systems Corporation, 2013-2017
Clinical Trials
- Long-Term Safety and Efficacy Study of Deucravacitinib in Participants With Systemic Lupus Erythematosus Start of enrollment: 2019 Mar 26
- An Investigational Study to Evaluate the Safety and Effectiveness of BMS-986165 With Background Treatment in Participants With Lupus Nephritis Start of enrollment: 2019 Jul 15
- Efficacy and Safety of AMG 570 in Subjects With Active Systemic Lupus Erythematosus (SLE) Start of enrollment: 2020 Feb 19
Publications & Presentations
PubMed
- 11 citationsPrevalence of clinically meaningful antiphospholipid antibodies in patients with systemic lupus erythematosus varies by race and ethnicity.Cécile M Yelnik, Xianhong Xie, Marta M Guerra, Nathalie Costedoat-Chalumeau, Arezou Khosroshahi
Annals of the Rheumatic Diseases. 2024-02-15 - 4 citationsImplications of the accuracy of diagnostic algorithms for systemic lupus on our understanding of racial disparities in pregnancy outcomes.Megan E B Clowse, James Oates, April Barnado, Katie Kirchoff, Ashley Blaske
Rheumatology. 2024-01-04 - 6 citationsUsing pooled electronic health records data to conduct pharmacoepidemiology safety studies: Challenges and lessons learned.Timothy Beukelman, Lang Chen, Narender Annapureddy, Jim Oates, Megan E B Clowse
Pharmacoepidemiology and Drug Safety. 2023-09-01
Journal Articles
- Stress Intervention and Disease in African American Lupus Patients: the Balancing Lupus Experiences with stress strategies (BLESS) studyWilliams E, Kamen D, Penfield M, Oates J, Health, 1/1/2014
- An Intervention to Reduce Psychosocial and Biological Indicators of stress in African American Lupus Patients: the Balancing Lupus Experiences with stress strategies s...Williams E, Penfield M, Kamen D, Oates J, Open Journal of Preventive Medicine, 1/1/2014
- NADPH oxidase and nitric oxide synthase dependent superoxide production is increased in proliferative lupus nephritisOates JC, Mashmoushi AK, Shaftman S, Gilkeson GS, Lupus, 1/1/2013
Books/Book Chapters
Press Mentions
Betty P. Tsao, PhD, Becomes Chair of Journal Publications CommitteeMarch 24th, 2025
Restoring This Enzyme's Function Protects Against Heart Disease in Lupus and BeyondMarch 28th, 2019
Richard M. Silver, MD, in the SpotlightDecember 18th, 2018
Grant Support
- Improving Health in Rheumatic Diseases (ImHeaRD)MEDICAL UNIVERSITY OF SOUTH CAROLINA2017–2027
- Targeting Pathogenic Endothelial Dysfunction in Lupus NephritisRALPH H JOHNSON VA MEDICAL CENTER2016–2027
- Targeting pathogenic endothelial dysfunction and lupus nephritisLupus Research Alliance2021–2023
- Peer Approaches to Lupus Self-Management (PALS)NINR2018–2023
- PREDICTIVE BIOMARKERS FOR DISEASE ACTIVITY AND ORGAN DAMAGE IN PATIENTS WITH LUPUSNIAMS2018–2023
Professional Memberships
- Member
- Southern Society for Clinical InvestigationFellow
- Henry Kunkel SocietyMember
- American Clinical and Climatological AssociationMember
- Royal Society of MedicineMember
External Links
- MUSC profilehttps://education.musc.edu/MUSCApps/facultydirectory/Oates-Jim
- MUSC Rheumatologyhttps://medicine.musc.edu/departments/dom/divisions/rheumatology-and-immunology/about/2023-year-in-review
- MUSC Rheumatologyhttps://medicine.musc.edu/departments/dom/divisions/rheumatology-and-immunology
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