James Potash, MD, Psychiatry, Baltimore, MD, Johns Hopkins Hospital

JamesBennettPotashMDMPH

Psychiatry Baltimore, MD

Henry Phipps Professor of Psychiatry and Behavioral Sciences, Department Director and Psychiatrist-in-Chief, Johns Hopkins Medicine

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Summary

  • Dr. Potash returned to Johns Hopkins as Director of Psychiatry and Psychiatrist-in-Chief in 2017. Prior to that he was Chair and Department Executive Officer of the University of Iowa Department of Psychiatry from 2011-17. Dr. Potash graduated in 1984 from Yale College, where he majored in English. Following graduation, he served in the Peace Corps in the West African country of Senegal, and there decided to become a physician. He completed his master’s degree in public health at Johns Hopkins, focusing on epidemiology and international health. He then went on to medical school at Hopkins, medical internship at Hopkins Bayview, and a year working as a general practitioner in another West African country, Benin. He returned to do his psychiatric residency at Hopkins and served as chief resident in 1997-98. He then joined the mood disorders program, and eventually became the program’s research director before moving to Iowa.

    Dr. Potash’s work has focused on investigation of the genetic and epigenetic basis of mood disorders—depression and bipolar disorder. These efforts have resulted in over 170 publications and consistent NIH funding. He has been particularly interested in the genetic basis of the psychotic forms of bipolar disorder, and in the epigenetic mechanisms through which stress plays a role in depression.

    Dr. Potash co-leads the Bipolar Sequencing Consortium, and is a member of the Council on Research for the American Psychiatric Association. He serves as Treasurer for the International Society for Psychiatric Genetics, and he has played a leading role in the National Network of Depression Centers.

    In addition to his research endeavors, Dr. Potash is also an active clinician who sees mood disorders patients in the inpatient and outpatient settings.

Education & Training

  • Johns Hopkins University
    Johns Hopkins UniversityRESIDENCY
  • Johns Hopkins Bayview Medical Center
    Johns Hopkins Bayview Medical CenterINTERNSHIP
  • Johns Hopkins University School of Medicine
    Johns Hopkins University School of MedicineMEDICAL_SCHOOL
  • Johns Hopkins School of Hygiene and Public Health
    Johns Hopkins School of Hygiene and Public HealthOTHER_TRAINING
  • Goucher CollegeOTHER_TRAINING
  • Yale College
    Yale CollegeOTHER_TRAINING

Certifications & Licensure

  • IA State Medical License
    IA State Medical License 2011 - 2018
  • MD State Medical License
    MD State Medical License 1994 - 2021
  • American Board of Psychiatry and Neurology Psychiatry

Awards, Honors, & Recognition

  • Independent Investigator Award NARSAD, 2008
  • Robins-Guze Award American Psychopathological Association, 2003
  • Mead Johnson Fellow in Public Psychiatry American Psychiatric Association, 1996
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Publications & Presentations

PubMed

Journal Articles

  • Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals  
    Battle A, Mostafavi S, Zhu X, Potash JB, Weissman MM, McCormick C, Haudenschild CD, Beckman KB, Shi J, Mei R, Urban AE, Montgomery SB, Levinson DF, and Koller D, Genome Res, 1/1/2014
  • Integrating GWAS and human protein interaction networks identifies a gene sub-network underlying alcohol dependence  
    Han S, Yang B-Z, Kranzler HR, Liu X, Zhao H, Farrer LA, Boerwinkle E, Potash JB, Gelernter J, Am J Hum Genet, 12/5/2013
  • Type I interferon signaling genes in recurrent major depression: increased expression detected by whole-blood RNA sequencing  
    Mostafavi S, Battle A, Zhu X, Potash JB, Weissman MM, Shi J, Beckman K, Haudenschild C, McCormick C, Mei R, Gameroff MJ, Gindes H, Adams P, Goes FS, Mondimore FM, MacK..., Mol Psychiatry, 12/3/2013
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Lectures

  • Psychiatry Postgraduate Conference 
    UI Carver College of Medicine, Iowa City, Iowa - 10/11/2013
  • Psychiatry Postgraduate Conference 
    UI Carver College of Medicine, Iowa City, Iowa - 10/11/2013

Press Mentions

  • Psilocybin Research at Johns Hopkins
    Psilocybin Research at Johns HopkinsOctober 21, 2019 21:59
  • Magic Mushrooms as Medicine? Johns Hopkins Scientists Launch Center for Psychedelic Research. Say Psychedelics Could Treat Alzheimer’s, Depression and Addiction
    Magic Mushrooms as Medicine? Johns Hopkins Scientists Launch Center for Psychedelic Research. Say Psychedelics Could Treat Alzheimer’s, Depression and AddictionSeptember 14, 2019 01:08
  • Companies Tout Psychiatric Pharmacogenomic Testing, but Is It Ready for a Store near You?
    Companies Tout Psychiatric Pharmacogenomic Testing, but Is It Ready for a Store near You?October 04, 2018 18:03
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Grant Support

  • A Genome-Wide Approach To The Epigenetics Of Stress And DepressionNational Institute Of Mental Health2011
  • 1/2 RARE Bipolar Loci Identification Through Synaptome SequencingNational Institute Of Mental Health2010–2011
  • A Genome-Wide Approach To The Epigenetics Of Stress And DepressionNational Institute Of Mental Health2010
  • Genetic Linkage And Association In Bipolar DisorderNational Institute Of Mental Health2005–2009
  • Genetics Of Early Onset DepressionNational Institute Of Mental Health2006–2008
  • Epigenetic Variation And Its Determinants In DepressionNational Institute Of Mental Health2005–2008
  • Studies Of Genomic Imprinting In Bipolar DisorderNational Institute Of Mental Health2001–2005

Professional Memberships

Hospital Affiliations