JamesMWilsonMD

PubMed

• Adeno-associated virus-mediated trastuzumab delivery to the central nervous system for human epidermal growth factor receptor 2+ brain metastasis.
  Marcela S Werner, Shweta Aras, Ashleigh R Morgan, Jillian Roamer, Nesteene J Param, Kanyin Olagbegi, R Jason Lamontagne, Jenny A Greig, James M Wilson> ;Cancer Gene Therapy. 2024 Mar 13
• High-dose systemic adeno-associated virus vector administration causes liver and sinusoidal endothelial cell injury.
  Juliette Hordeaux, R Jason Lamontagne, Chunjuan Song, George Buchlis, Cecilia Dyer, Elizabeth L Buza, Ali Ramezani, Erik Wielechowski, Jenny A Greig, Jessica A Chiches...> ;Molecular Therapy. 2024 Apr 3
• 9 citations
  Integrated vector genomes may contribute to long-term expression in primate liver after AAV administration.
  Jenny A Greig, Kelly M Martins, Camilo Breton, R Jason Lamontagne, Yanqing Zhu, Zhenning He, John White, Jing-Xu Zhu, Jessica A Chichester, Qi Zheng, Zhe Zhang, Peter ...> ;Nature Biotechnology. 2023 Nov 6
• 2 citations
  Quantification of human mature frataxin protein expression in nonhuman primate hearts after gene therapy.
  Teerapat Rojsajjakul, Juliette J Hordeaux, Gourav R Choudhury, Christian J Hinderer, Clementina Mesaros, James M Wilson, Ian A Blair> ;Communications Biology. 2023 Oct 27
• 1 citations
  Positron Emission Tomography Quantitative Assessment of Off-Target Whole-Body Biodistribution of I-124-Labeled Adeno-Associated Virus Capsids Administered to Cerebral ...
  Jonathan B Rosenberg, Edward K Fung, Jonathan P Dyke, Bishnu P De, Howard Lou, James M Kelly, Layla Reejhsinghani, Rodolfo J Ricart Arbona, Dolan Sondhi, Stephen M Kam...> ;Human Gene Therapy. 2023 Nov 1
• 1 citations
  Significant Differences in Capsid Properties and Potency Between Adeno-Associated Virus Vectors Produced in Sf9 and HEK293 Cells.
  April Giles, Martin Lock, Shu-Jen Chen, Kevin Turner, Gregg Wesolowski, Andrew Prongay, Boris N Petkov, Kanyin Olagbegi, Hanying Yan, James M Wilson> ;Human Gene Therapy. 2023 Oct 1
• 1 citations
  Determining the Minimally Effective Dose of a Clinical Candidate AAV Vector in a Mouse Model of Hemophilia A.
  Jenny A. Greig, Melanie K. Smith, Jayme M.L. Nordin, Tamara Goode, Edward A. Chroscinski, Elizabeth L. Buza, Nicole Schmidt, Lisa M. Kattenhorn, Samuel C. Wadsworth, J...> ;Human Gene Therapy. 2021 Oct 15
• 9 citations
  Association of baseline hematoma and edema volumes with one-year outcome and long-term survival after spontaneous intracerebral hemorrhage: A community-based inception...
  James J M Loan, Angus B Gane, Laura Middleton, Brendan Sargent, Tom J Moullaali, Mark Rodrigues, Laura Cunningham, Joanna M. Wardlaw, Rustam Al-Shahi Salman, Neshika S...> ;International Journal of Stroke. 2021 Oct 1
• 42 citations
  An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates.
  Nerea Zabaleta, Wenlong Dai, U. Bhatt, Cécile Hérate, Pauline Maisonnasse, Jessica A. Chichester, Julio Sanmiguel, Reynette Estelien, Kristofer T. Michalson, Cheikh Ta...> ;Cell Host & Microbe. 2021 Sep 8
• 2 citations
  Isolating Natural Adeno-Associated Viruses from Primate Tissues with a High-Fidelity Polymerase.
  Qiang Wang, Kalyani Nambiar, James M. Wilson> ;Human Gene Therapy. 2021 Aug 26
• 4 citations
  Adeno-Associated Virus Vector-Mediated Expression of Antirespiratory Syncytial Virus Antibody Prevents Infection in Mouse Airways.
  Josh Tycko, Virginie S. Adam, Marco Crosariol, Jason Ohlstein, Julio Sanmiguel, Anna Tretiakova, Soumitra Roy, Stefan Worgall, James M. Wilson, Maria P. Limberis> ;Human Gene Therapy. 2021 Aug 20
• 5 citations
  Muscle-directed AAV gene therapy rescues the maple syrup urine disease phenotype in a mouse model
  Jenny A. Greig, Matthew Jennis, Aditya Dandekar, Joanna K. Chorazeczewski, Melanie K. Smith, Scott N. Ashley, Hanying Yan, James M. Wilson> ;Molecular Genetics and Metabolism. 2021 Aug 17
• 10 citations
  Context-Specific Function of the Engineered Peptide Domain of PHP.B.
  R. Alexander Martino, Edwin C. Fluck, Jacqueline Murphy, Qiang Wang, Henry Hoff, Ruth A. Pumroy, Claudia Y. Lee, Joshua J. Sims, Soumitra Roy, Vera Y. Moiseenkova-Bell...> ;Journal of Virology. 2021 Aug 4
• 26 citations
  Intranasal gene therapy to prevent infection by SARS-CoV-2 variants.
  Joshua J. Sims, Jenny A. Greig, Kristofer T. Michalson, Sharon Lian, R. Alexander Martino, Rosemary Meggersee, Turner Kevin, Kalyani Nambiar, Cecilia Dyer, Christian H...> ;Plos Pathogens. 2021 Jul 15
• 91 citations
  Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device.
  Sarah J. Shepherd, Claude C. Warzecha, Sagar Yadavali, Rakan El-Mayta, Mohamad-Gabriel Alameh, Lili Wang, Drew Weissman, James M. Wilson, David Issadore, Michael J. Mi...> ;Nano Letters. 2021 Jul 14
• 35 citations
  Long-term stable reduction of low-density lipoprotein in nonhuman primates following in vivo genome editing of PCSK9.
  Lili Wang, Camilo Breton, Claude C. Warzecha, Peter Bell, Hanying Yan, Zhenning He, John H. White, Yanqing Zhu, Mingyao Li, Elizabeth L. Buza, Derek Jantz, James M. Wi...> ;Molecular Therapy. 2021 Jun 2
• 2 citations
  Geographical variation in the carbon, nitrogen, and phosphorus content of blue mussels, Mytilus edulis.
  Andrew van der Schatte Olivier, Lewis Le Vay, Shelagh K. Malham, Michael Christie, James M. Wilson, Susan Allender, Sarah Schmidlin, Jordan Brewin, Laurence Jones> ;Marine Pollution Bulletin. 2021 Jun 1
• 11 citations
  Developing a second-generation clinical candidate AAV vector for gene therapy of familial hypercholesterolemia.
  Lili Wang, Ilayaraja Muthuramu, Suryanarayan Somanathan, Hong Zhang, Peter Bell, Zhenning He, Hongwei Yu, Yanqing Zhu, Anna Tretiakova, James M. Wilson> ;Molecular Therapy. Methods & Clinical Development. 2021 May 5
• TRIBUTE TO MAVIS AGBANDJE-MCKENNA A Beautiful Mind and the Heart of an Explorer
  José M. Almendral, Aravind Asokan, Kenneth Ira Berns, Michael Chapman, Sawati Chatterjee, Jay Chiorini, Terry R. Flotte, Guangping Gao, Dirk Grimm, William W. Hauswirt...> ;Human Gene Therapy. 2021 Apr 1
• 11 citations
  Increasing the specificity of AAV-based gene editing through self-targeting and short promoter strategies
  Camilo Breton, Thomas Furmanak, Alexa N. Avitto, Melanie K. Smith, Caitlin Latshaw, Hanying Yan, Jenny A. Greig, James M. Wilson> ;Molecular Therapy. 2021 Mar 3
• 25 citations
  CRISPR/Cas9 directed to the Ube3a antisense transcript improves Angelman syndrome phenotype in mice.
  Ralf S. Schmid, Xuefeng Deng, Priyalakshmi Panikker, Msema Msackyi, Camilo Breton, James M. Wilson> ;The Journal of Clinical Investigation. 2021 Mar 1
• 50 citations
  Helper lipid structure influences protein adsorption and delivery of lipid nanoparticles to spleen and liver.
  Rui Zhang, Rakan El-Mayta, Timothy J. Murdoch, Claude C. Warzecha, Margaret M. Billingsley, Sarah J. Shepherd, Ningqiang Gong, Lili Wang, James M. Wilson, Daeyeon Lee,...> ;Biomaterials Science. 2021 Feb 23
• 4 citations
  Modified Adenovirus Prime-Protein Boost Clade C HIV Vaccine Strategy Results in Reduced Viral DNA in Blood and Tissues Following Tier 2 SHIV Challenge.
  Delphine C. Malherbe, Lo Vang, Jason Mendy, Philip Barnette, David A. Spencer, Jason S. Reed, Bettie W. Kareko, D. Noah Sather, Shilpi Pandey, Constantinos Kurt Wibmer...> ;Frontiers in Immunology. 2021 Feb 15
• 8 citations
  Novel Rickettsia Species Infecting Dogs, United States.
  James M. Wilson, Edward B. Breitschwerdt, Nicholas B. Juhasz, Henry S. Marr, Joao Felipe de Brito Galvão, Carmela L Pratt, Barbara A. Qurollo> ;Emerging Infectious Diseases. 2020 Dec 1
• Correction to: ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome ed...
  Camilo Breton, Peter M Clark, Lili Wang, Jenny A Greig, James M Wilson> ;BMC Genomics. 2020 Nov 20
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Lectures

• Biologic Therapeutics Seminar Series - In Vivo Gene Transfer for Genetic Disease: Progress & Challenges 
  Washington University School of Medicine, Saint Louis, Missouri - 1/25/2012