JamesWitekMD

PubMed

• 2 citations
  The Hospital Recovery Scale: A clinically useful endpoint in patients hospitalized with influenza.
  Wilbert van Duijnhoven, Ilse Van Dromme, Steven Haesendonckx, James Witek, Lorant Leopold> ;Contemporary Clinical Trials. 2022 Dec 1
• Measuring respiratory syncytial virus infection severity in hospitalized children using the Pediatric Respiratory Syncytial Virus Electronic Severity and Outcome Ratin...
  Yannick Vandendijck, Jane Scott, Dirk Heerwegh, Wim Van Der Elst, James Witek, Rekha Sinha, Hein Fennema> ;Influenza and Other Respiratory Viruses. 2022 Nov 1
• 15 citations
  Risk Factors and Medical Resource Utilization of Respiratory Syncytial Virus, Human Metapneumovirus, and Influenza-Related Hospitalizations in Adults-A Global Study Du...
  Ann R Falsey, Edward E Walsh, Stacey House, Yannick Vandenijck, Xiaohui Ren, Sofia Keim, Diye Kang, Pascale Peeters, James Witek, Gabriela Ispas> ;Open Forum Infectious Diseases. 2021 Nov 1
• 15 citations
  Comparative assessment of reported symptoms of influenza, respiratory syncytial virus, and human metapneumovirus infection during hospitalization and post-discharge as...
  Ann R. Falsey, Edward E. Walsh, Richard H. Osborne, Yannick Vandendijck, Xiaohui Ren, James Witek, Diye Kang, Eric K. H. Chan, Jane Scott, Gabriela Ispas> ;Influenza and Other Respiratory Viruses. 2021 Sep 2
• 7 citations
  Virology analyses of HCV genotype 4 isolates from patients treated with simeprevir and peginterferon/ribavirin in the Phase III RESTORE study
  Bart Fevery, Thierry Verbinnen, Monika Peeters, Katrien Janssen, James Witek, W. Jessner, S. De Meyer, Oliver Lenz> ;Journal of Viral Hepatitis. 2017 Jan 1
• 145 citations
  Simeprevir plus sofosbuvir (12 and 8 weeks) in hepatitis C virus genotype 1-infected patients without cirrhosis: OPTIMIST-1, a phase 3, randomized study
  Paul Y. Kwo, Norman Gitlin, Ronald Nahass, David E. Bernstein, K.P. Etzkorn, Sergio Rojter, Eugene R. Schiff, M. Davis, Peter Ruane, Ziad Younes, R. Kalmeijer, Rekha S...> ;Hepatology. 2016 Aug 1
• 146 citations
  Simeprevir plus sofosbuvir in patients with chronic hepatitis C virus genotype 1 infection and cirrhosis: A phase 3 study (OPTIMIST-2)
  Eric Lawitz, Gary Matusow, Edwin DeJesus, Eric M. Yoshida, Franco Felizarta, Reem Ghalib, Eliot Godofsky, Robert Herring, Gary Poleynard, Aasim Sheikh, Hillel Tobias, ...> ;Hepatology. 2016 Aug 1
• 4 citations
  Efficacy of telaprevir-based therapy in stable liver transplant patients with chronic genotype 1 hepatitis C
  Xavier Forns, Didier Samuel, David Mutimer, Stefano Fagiuoli, Miquel Navasa, Kosh Agarwal, Marina Berenguer, Massimo Colombo, Kerstin Herzer, Frederik Nevens, Bjorn Da...> ;Annals of Hepatology. 2016 Jul 1
• 8 citations
  Simeprevir plus peginterferon/ribavirin for HCV genotype 1-infected treatment-naïve patients in China and South Korea.
  Lai Wei, Tao Han, Dongliang Yang, Jeong Heo, Jia Shang, Jun Cheng, Xinyue Chen, Qing Xie, Ju Hyun Kim, R. Kalmeijer, Sivi Ouwerkerk-Mahadevan, Eva Hoeben, Oliver Lenz,...> ;Journal of Gastroenterology and Hepatology. 2016 May 1
• 5 citations
  Pre-existence and Persistence of Resistant Minority Hepatitis C Virus Variants in Genotype 1-Infected Patients Treated With Simeprevir/Peginterferon/Ribavirin.
  Bart Fevery, Kim Thys, Veerle Van Eygen, Thierry Verbinnen, Elizabeth Van Rossem, Annemie Buelens, Jeroen Aerssens, James Witek, Gaston Picchio, Sandra De Meyer, Olive...> ;Open Forum Infectious Diseases. 2016 Apr 1
• 2 citations
  Telaprevir-based therapy in patients coinfected with chronic hepatitis C virus infection and HIV: INSIGHT study.
  María Luisa Montes, Mark T. Nelson, Pierre-Marie Girard, Joe Sasadeusz, Andrzej Horban, Beatriz Grinsztejn, Natalia Zakharova, Antonio Rivero, Jacques Durant, Enrique ...> ;The Journal of Antimicrobial Chemotherapy. 2016 Jan 1
• 2 citations
  Pharmacokinetics of bound and unbound telaprevir in cirrhotic patients with moderate and severe hepatic impairment
  Sivi Ouwerkerk-Mahadevan, Atef Halabi, Blanka Cieslarová, Indra Aerts, James Witek, Rodica Van Solingen-Ristea, Donghan Luo> ;Journal of Clinical Pharmacology. 2015 Oct 1
• 10 citations
  Evolution of Hepatitis C Virus Quasispecies during Repeated Treatment with the NS3/4A Protease Inhibitor Telaprevir
  Simone Susser, Mathieu Flinders, Henk W. Reesink, Stefan Zeuzem, Glenn Lawyer, Anne Ghys, Veerle Van Eygen, James Witek, Sandra De Meyer, Christoph Sarrazin> ;Antimicrobial Agents and Chemotherapy. 2015 May 1
• 88 citations
  Prevalence of the hepatitis C virus NS3 polymorphism Q80K in genotype 1 patients in the European region.
  Christoph Sarrazin, Erkki Lathouwers, Monika Peeters, Bjorn Daems, Annemie Buelens, James Witek, Yves Wyckmans, Bart Fevery, Thierry Verbinnen, Anne Ghys, M. Schlag, A...> ;Antiviral Research. 2015 Apr 1
• 14 citations
  An OPTIMIZE Study Retrospective Analysis for Management of Telaprevir-Treated Hepatitis C Virus (HCV)-Infected Patients by Use of the Abbott RealTime HCV RNA Assay
  Christoph Sarrazin, I. Dierynck, Gavin Cloherty, Anne Ghys, Katrien Janssen, Donghan Luo, James Witek, Maria Buti, Gaston Picchio, Sandra De Meyer> ;Journal of Clinical Microbiology. 2015 Apr 1
• 5 citations
  Ribavirin concentration determines treatment success of first-generation DAA-based chronic HCV therapy.
  Clara T. M. M. de Kanter, Maria Buti, Ralph DeMasi, Sivi Ouwerkerk-Mahadevan, Anton S M Dofferhoff, James Witek, Joost P.H. Drenth, Stefan Zeuzem, David M. Burger> ;Antiviral Therapy. 2015 Feb 1
• 5 citations
  Incidence of virological failure and emergence of resistance with twice-daily vs every 8-h administration of telaprevir in the OPTIMIZE study.
  I. Dierynck, Anne Ghys, James Witek, Donghan Luo, Katrien Janssen, Bjorn Daems, Gaston Picchio, Maria Buti, S. De Meyer> ;Journal of Viral Hepatitis. 2014 Dec 1
• 19 citations
  Risk factors predictive of anemia development during telaprevir plus peginterferon/ribavirin therapy in treatment-experienced patients.
  Stefan Zeuzem, Ralph DeMasi, Alessandra Baldini, Bruce Coate, Donghan Luo, Joseph Mrus, James Witek> ;Journal of Hepatology. 2014 Jun 1
• 20 citations
  Pharmacokinetic interaction between etravirine or rilpivirine and telaprevir in healthy volunteers: A randomized, two-way crossover trial.
  Thomas N. Kakuda, Lorant Leopold, Steven Nijs, Ann Vandevoorde, Herta Crauwels, Kirk Bertelsen, Marita Stevens, James Witek, Yvon van Delft, Frank Tomaka, Richard M. W...> ;Journal of Clinical Pharmacology. 2014 May 1
• 40 citations
  Telaprevir twice daily is noninferior to telaprevir every 8 hours for patients with chronic hepatitis C.
  Maria Buti, Kosh Agarwal, Yves Horsmans, William Sievert, Ewa Janczewska, Stefan Zeuzem, L. Nyberg, Robert S. Brown, Christophe Hézode, Mario Rizzetto, Raymundo Paraná...> ;Gastroenterology. 2014 Mar 1
• 6 citations
  Telaprevir combination therapy in HCV/HIV co-infected patients (insight study): sustained virologic response at 12 weeks final analysis
  Marisa Montes, Mark T. Nelson, Pierre Marie Girard, Joe Sasadeusz, Andrzej Horban, Beatriz Grinsztejn, Natalia Zakharova, Antonio Rivero, Erkki Lathouwers, Katrien Jan...> ;Journal of the International AIDS Society. 2014 Feb 11
• 21 citations
  Homeostasis model assessment of insulin resistance does not seem to predict response to telaprevir in chronic hepatitis C in the REALIZE trial
  Zobair M. Younossi, Francesco Negro, Lawrence Serfaty, Stanislas Pol, Moisés Diago, Stefan Zeuzem, Pietro Andreone, Eric Lawitz, Stuart K. Roberts, R. Focaccia, Graham...> ;Hepatology. 2013 Dec 1
• 23 citations
  Pharmacokinetic Interaction between Telaprevir and Methadone
  Rolf van Heeswijk, Peter Verboven, Ann Vandevoorde, Petra Vinck, Jan Snoeys, Griet Boogaerts, Els De Paepe, Rodica Van Solingen-Ristea, James Witek, Varun Garg> ;Antimicrobial Agents and Chemotherapy. 2013 May 1
• 10 citations
  Steady-State Pharmacokinetics of Etravirine and Lopinavir/Ritonavir Melt Extrusion Formulation, Alone and in Combination, in Healthy HIV-Negative Volunteers
  Monika Schöller-Gyüre, Thomas N. Kakuda, James Witek, Sophie H. Akuma, Goedele De Smedt, Kurt Spittaels, Veerle Vyncke, Richard M. W. Hoetelmans> ;Journal of Clinical Pharmacology. 2013 Feb 1
• 7 citations
  Pharmacokinetics and Short-Term Safety of Etravirine in Combination With Fluconazole or Voriconazole in HIV-Negative Volunteers
  Thomas N. Kakuda, Rodica Van Solingen-Ristea, Fatima Aharchi, Goedele De Smedt, James Witek, Steven Nijs, Veerle Vyncke, Richard M. W. Hoetelmans> ;Journal of Clinical Pharmacology. 2013 Jan 1
• Join now to see all