JamesMauriceYouakimMD

Psychiatry • Princeton, NJ

Vice President, Clinical Development Acadia Pharmaceuticals

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Office
502 Carnegie Center
Suite 300
Princeton, NJ 08540
Phone+1 609-250-6896
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Education & Training

Baylor College of MedicineResidency, Psychiatry, 1989 - 1993
Baylor College of MedicineClass of 1989

Certifications & Licensure

PA State Medical License 1993 - 2024
American Board of Psychiatry and Neurology Psychiatry
American Board of Sleep MedicineSleep Medicine

Clinical Trials

A Study of the Safety and Efficacy of Pimavanserin in Patients With Alzheimer's Disease Psychosis Start of enrollment: 2013 Nov 01
Completed
Phase 2
Study to Examine the Safety and Efficacy of Pimavanserin for the Treatment of Agitation and Aggression in Alzheimer's Disease (SERENE) Start of enrollment: 2016 Nov 01
Terminated
Phase 2
A Study of Pimavanserin for the Treatment of Agitation and Aggression in Subjects With Alzheimer's Disease Start of enrollment: 2017 Feb 23
Completed
Phase 2
Relapse Prevention Study of Pimavanserin in Dementia-related Psychosis Start of enrollment: 2017 Sep 27
Completed
Phase 3
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Publications & Presentations

PubMed

48 citations
Trial of Pimavanserin in Dementia-Related Psychosis
Pierre N. Tariot, Jeffrey L. Cummings, Maria E. Soto-Martin, Clive Ballard, Deniz E. Erten-Lyons, David L. Sultzer, Davangere P. Devanand, Daniel Weintraub, Bradley W....> ;The New England Journal of Medicine. 2021 Jul 21
26 citations
Pimavanserin in Alzheimer's Disease Psychosis: Efficacy in Patients with More Pronounced Psychotic Symptoms.
Clive Ballard, James M. Youakim, Bruce Coate, Srdjan Stankovic> ;The Journal of Prevention of Alzheimer's Disease. 2018 Jan 1
45 citations
Pimavanserin: Potential Treatment For Dementia-Related Psychosis.
Jeffrey L. Cummings, Clive Ballard, Pierre N. Tariot, Randy Owen, Erin P. Foff, James M. Youakim, James C. Norton, Srdjan Stankovic> ;The Journal of Prevention of Alzheimer's Disease. 2018 Jan 1
32 citations
Revisiting Criteria for Psychosis in Alzheimer’s Disease and Related Dementias: Toward Better Phenotypic Classification and Biomarker Research
Corinne E. Fischer, Zahinoor Ismail, James M. Youakim, Byron Creese, Sanjeev Kumar, Nicolas A. Nunez, R. Ryan Darby, Antonella Di Vita, Fabrizia D'Antonio, Carlo de Le...> ;Journal of Alzheimer's Disease. 2020 Jan 1
104 citations
Evaluation of the safety, tolerability, and efficacy of pimavanserin versus placebo in patients with Alzheimer's disease psychosis: a phase 2, randomised, placebo-cont...
Clive Ballard, Carol Banister, Zunera Khan, Jeffrey L. Cummings, George Demos, Bruce Coate, James M. Youakim, Randall Owen, Srdjan Stankovic, Elaine B Tomkinson, Joann...> ;The Lancet. Neurology. 2018 Mar 1
120 citations
Adjunctive brexpiprazole 1 and 3 mg for patients with major depressive disorder following inadequate response to antidepressants: a phase 3, randomized, double-blind s...
Michael E. Thase, James M. Youakim, Aleksandar Skuban, Mary Hobart, Peter Zhang, Robert D. McQuade, Margaretta Nyilas, William H. Carson, Raymond Sanchez, Hans Eriksson> ;The Journal of Clinical Psychiatry. 2015 Sep 23
121 citations
Efficacy and Safety of Adjunctive Brexpiprazole 2 mg in Major Depressive Disorder: A Phase 3, Randomized, Placebo-Controlled Study in Patients With Inadequate Response...
Michael E. Thase, James M. Youakim, Aleksandar Skuban, Mary Hobart, Carole Augustine, Peter Zhang, Robert D. McQuade, William H. Carson, Margaretta Nyilas, Raymond San...> ;The Journal of Clinical Psychiatry. 2015 Sep 23
11 citations
Investigation of a possible interaction between quetiapine and armodafinil in patients with schizophrenia: an open-label, multiple-dose study.
Mona Darwish, Mary Bond, Edward T. Hellriegel, James M. Youakim, Ronghua Yang, Philmore Robertson> ;Journal of Clinical Pharmacology. 2012 Sep 1
22 citations
Adjunctive armodafinil for negative symptoms in adults with schizophrenia: a double-blind, placebo-controlled study.
John M. Kane, Ronghua Yang, James M. Youakim> ;Schizophrenia Research. 2012 Mar 1
35 citations
Armodafinil as adjunctive therapy in adults with cognitive deficits associated with schizophrenia: a 4-week, double-blind, placebo-controlled study.
John M. Kane, Deepak Cyril D'Souza, Ashwin A. Patkar, James M. Youakim, Jane M. Tiller, Ronghua Yang, Richard S.E. Keefe> ;The Journal of Clinical Psychiatry. 2010 Aug 24
60 citations
Adjunctive Armodafinil for Major Depressive Episodes Associated With Bipolar I Disorder: A Randomized, Multicenter, Double-Blind, Placebo-Controlled, Proof-of-Concept ...
Joseph R. Calabrese, Terence A. Ketter, James M. Youakim, Jane M. Tiller, Ronghua Yang, Mark A. Frye> ;The Journal of Clinical Psychiatry. 2010 Jul 27
18 citations
A phase 3, double-blind, randomized, placebo-controlled study of armodafinil for excessive sleepiness associated with jet lag disorder.
Russell Rosenberg, Richard K. Bogan, Jane M. Tiller, Ronghua Yang, James M. Youakim, Craig Q. Earl, Thomas Roth> ;Mayo Clinic Proceedings. 2010 Jul 1
36 citations
IDENTITY TRANSFORMATION IN MEDICAL STUDENTS
Mitchell J M Cohen, Abigail Kay, James M. Youakim, John M Balaicuis> ;American Journal of Psychoanalysis. 2009 Mar 16
Marriage in the Context of Immigration
James M. Youakim> ;American Journal of Psychoanalysis. 2004 Jun 1
17 citations
Efficacy of Laser-Assisted Uvulopalatoplasty in Obstructive Sleep Apnea:
Edmund A. Pribitkin, Sharon L. Schutte, William M. Keane, Vivian Mao, Jacqueline R. Cater, Karl Doghramji, James M. Youakim, Marc Rosen, William Breuninger> ;Otolaryngology--Head and Neck Surgery. 1998 Dec 1
55 citations
Posttraumatic stress disorder and obstructive sleep apnea syndrome.
James M. Youakim, Karl Doghramji, Sharon L. Schutte> ;Psychosomatics. 1998 Mar 1
177 citations
A normative study of the maintenance of wakefulness test (MWT).
Karl Doghramji, Merrill M. Mitler, R. Bart Sangal, Colin M. Shapiro, Sheila R. Taylor, Joyce A. Walsleben, Cynthia Belisle, Milton K. Erman, Rosa Hayduk, Rima Hosn, Ed...> ;Electroencephalography and Clinical Neurophysiology. 1997 Nov 1
Molecules and minds.
Youakim, J. M., Doghramji, K.> ;Lancet. 1994 Jun 11
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JamesMauriceYouakimMD

Dr. Youakim is on Doximity

Education & Training

Certifications & Licensure

Clinical Trials

Publications & Presentations

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