JamieKuckMDPhD

PubMed

• 20 citations
  Cell-free hemoglobin augments acute kidney injury during experimental sepsis
  Ciara M. Shaver, Melinda G. Paul, Nathan D. Putz, Stuart R. Landstreet, Jamie L. Kuck, Lauren Scarfe, Nataliya I. Skrypnyk, Haichun Yang, Fiona E. Harrison, Mark P. de...> ;American Journal of Physiology. Renal Physiology. 2019 Oct 1
• 25 citations
  Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury
  Ciara M. Shaver, Nancy E. Wickersham, J. Brennan McNeil, Hiromasa Nagata, Adam Miller, Stuart R. Landstreet, Jamie L. Kuck, Joshua M. Diamond, David J. Lederer, Steven...> ;JCI Insight. 2018 Jan 25
• 33 citations
  Ascorbic acid attenuates endothelial permeability triggered by cell-free hemoglobin.
  Jamie L. Kuck, Julie A. Bastarache, Ciara M. Shaver, Joshua P. Fessel, Sergey Dikalov, James M. May, Lorraine B. Ware> ;Biochemical and Biophysical Research Communications. 2018 Jan 1
• 5 citations
  Cell-Free Hemoglobin-mediated Increases in Vascular Permeability. A Novel Mechanism of Primary Graft Dysfunction and a New Therapeutic Target
  Ciara M. Shaver, Nancy Wickersham, J. Brennan McNeil, Hiromasa Nagata, Gillian Sills, Jamie L. Kuck, David R. Janz, Julie A. Bastarache, Lorraine B. Ware> ;Annals of the American Thoracic Society. 2017 Sep 1
• 22 citations
  Mitochondrial DNA Damage Initiates Acute Lung Injury and Multi-Organ System Failure Evoked in Rats by Intra-Tracheal Pseudomonas Aeruginosa.
  Yann Leei Lee, Boniface Obiako, Olena M. Gorodnya, Mykhaylo V. Ruchko, Jamie L. Kuck, Viktor M. Pastukh, Glenn L. Wilson, Jon D. Simmons, Mark N. Gillespie> ;Shock. 2017 Jul 1
• 55 citations
  Mitochondrial DNA damage-associated molecular patterns mediate a feed-forward cycle of bacteria-induced vascular injury in perfused rat lungs
  Jamie L. Kuck, Boniface Obiako, Olena M. Gorodnya, Viktor M. Pastukh, Justin Kua, Jon D. Simmons, Mark N. Gillespie> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2015 May 15
• 52 citations
  Mitochondrially targeted Endonuclease III has a powerful anti-infarct effect in an in vivo rat model of myocardial ischemia/reperfusion
  Xi-Ming Yang, Lin Cui, James White, Jamie L. Kuck, Mykhaylo V. Ruchko, Glenn L. Wilson, Mikhail Alexeyev, Mark N. Gillespie, James M. Downey, Michael V. Cohen> ;Basic Research in Cardiology. 2015 Jan 17
• 178 citations
  Elevated levels of plasma mitochondrial DNA DAMPs are linked to clinical outcome in severely injured human subjects.
  Jon D. Simmons, Yann Leei Lee, Sujata Mulekar, Jamie L. Kuck, Richard P. Gonzalez, Mark N. Gillespie, William O. Richards> ;Annals of Surgery. 2013 Oct 1
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