JaneC.DengMDM.S.

Pulmonology • Ann Arbor, MI

Critical Care Medicine, Infectious Disease, Interstitial Lung Diseases, Pleural Disease

Associate Professor, Medicine, University of Michigan School of Medicine

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Office
2215 Fuller Rd
111G Pulmonary
Ann Arbor, MI 48105
Phone+1 734-845-3039
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Education & Training

University of Michigan Health SystemFellowship, Pulmonary Disease and Critical Care Medicine, 2001 - 2004
University of Michigan Medical CenterPost-Doctoral Fellowship, NIH Training Grant, 2000 - 2001
University of Michigan Health SystemResidency, Internal Medicine, 1997 - 2000
University of California San Francisco School of MedicineClass of 1997

Certifications & Licensure

MI State Medical License 1997 - 2026
CA State Medical License 2005 - 2025
American Board of Internal Medicine Critical Care Medicine

Publications & Presentations

PubMed

2 citations
Itaconate suppresses atherosclerosis by activating a Nrf2-dependent antiinflammatory response in macrophages in mice.
Jianrui Song, Yanling Zhang, Ryan A Frieler, Anthony Andren, Sherri Wood, Daniel J Tyrrell, Peter Sajjakulnukit, Jane C Deng, Costas A Lyssiotis, Richard M Mortensen, ...> ;The Journal of Clinical Investigation. 2023 Dec 12
Barriers to Timely Lung Cancer Care in Early Stage Non-Small Cell Lung Cancer and Impact on Patient Outcomes.
Mina Pirzadeh, Madeline Lagina, Cameron Wood, Thomas Valley, Nithya Ramnath, Douglas Arenberg, Jane C Deng> ;Clinical Lung Cancer. 2024 Mar 1
Detailed Mechanisms Underlying Neutrophil Bactericidal Activity against.
Zachary Tsai, Kyle A Carver, Henry H Gong, Kosuke Kosai, Jane C Deng, Matthew J Worley> ;Biomedicines. 2023 Aug 11
10 citations
Age-induced prostaglandin Eimpairs mitochondrial fitness and increases mortality to influenza infection.
Judy Chen, Jane C Deng, Rachel L Zemans, Karim Bahmed, Beata Kosmider, Min Zhang, Marc Peters-Golden, Daniel R Goldstein> ;Nature Communications. 2022 Nov 9
12 citations
How aging impacts vaccine efficacy: known molecular and cellular mechanisms and future directions.
Judy Chen, Jane C Deng, Daniel R Goldstein> ;Trends in Molecular Medicine. 2022 Dec 1
4 citations
Neutrophils drive pulmonary vascular leakage in MHV-1 infection of susceptible A/J mice.
Henry H Gong, Matthew J Worley, Kyle A Carver, Daniel R Goldstein, Jane C Deng> ;Frontiers in Immunology. 2022 Jan 1
7 citations
Heterogeneity of neutrophils and inflammatory responses in patients with COVID-19 and healthy controls.
Jintao Xu, Bing He, Kyle Carver, Debora Vanheyningen, Brian Parkin, Lana X Garmire, Michal A Olszewski, Jane C Deng> ;Frontiers in Immunology. 2022 Jan 1
1 citations
A “Fluid” Diagnosis
Owen Albin, John P. Mills, Sanjay Saint, Michele S. Swanson, Jane C. Deng> ;The New England Journal of Medicine. 2021 Dec 1
31 citations
Seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection among Veterans Affairs healthcare system employees suggests higher risk of inf...
Derek E Dimcheff, Richard J Schildhouse, Mark S Hausman, Brenda M. Vincent, Erica Markovitz, Stephen W. Chensue, Jane Deng, Melissa McLeod, Danielle Hagan, Jon Russell...> ;Infection Control and Hospital Epidemiology. 2021 Apr 1
A 35-Year-Old Smoker With Dyspnea and Chest Pain.
Matthew K. Hensley, Jane C. Deng> ;Chest. 2020 Dec 1
2 citations
Development of secondary bacterial pneumonia in adults presenting with influenza versus noninfluenza viral respiratory infection.
Kathryn H. Melamed, Justin Williams, Xiaoyan Wang, Scott Hu, Christopher Nguyen, Jing Cui, Jane C. Deng> ;Therapeutic Advances in Respiratory Disease. 2020 Oct 29
16 citations
CCR2 mediates increased susceptibility to post-H1N1 bacterial pneumonia by limiting dendritic cell induction of IL-17
Stephen J. Gurczynski, Niket Nathani, Helen I Warheit-Niemi, Elissa M Hult, Amy B. Podsiad, Jane C. Deng, Rachel L. Zemans, Urvashi Bhan, Bethany B. Moore> ;Mucosal Immunology. 2019 Mar 1
70 citations
Excessive neutrophil levels in the lung underlie the age-associated increase in influenza mortality.
Upasana Kulkarni, Rachel L. Zemans, Candice A. Smith, Sherri C. Wood, Jane C. Deng, Daniel R. Goldstein> ;Mucosal Immunology. 2019 Jan 7
278 citations
Respiratory Viral Infection-Induced Microbiome Alterations and Secondary Bacterial Pneumonia.
Shigeo Hanada, Mina Pirzadeh, Kyle Y. Carver, Jane C. Deng> ;Frontiers in Immunology. 2018 Nov 16
19 citations
Acute on Chronic Liver Failure and Immune Dysfunction: A Mimic of Sepsis.
Matthew K. Hensley, Jane C. Deng> ;Seminars in Respiratory and Critical Care Medicine. 2018 Oct 1
22 citations
Generation of a Live Attenuated Influenza Vaccine that Elicits Broad Protection in Mice and Ferrets
Lulan Wang, Su-Yang Liu, Hsiang Wen Chen, Xu Juan, Maxime Chapon, Tao Zhang, Fan Zhou, Yao E. Wang, Natalie Quanquin, Guiqin Wang, Xiaoli Tian, Zhanlong He, Longding L...> ;Cell Host & Microbe. 2017 Mar 8
31 citations
Postviral Complications: Bacterial Pneumonia.
Jason E. Prasso, Jane C. Deng> ;Clinics in Chest Medicine. 2017 Mar 1
25 citations
Epithelial Cell-Derived Secreted and Transmembrane 1a Signals to Activated Neutrophils during Pneumococcal Pneumonia.
Hirofumi Kamata, Kazuko Yamamoto, Gregory A. Wasserman, Mary C Zabinski, Constance Yuen, Wing Yi Lung, Adam C. Gower, Anna C. Belkina, Maria I. Ramirez, Jane C. Deng, ...> ;American Journal of Respiratory Cell and Molecular Biology. 2016 Sep 1
33 citations
Prediction of Clinical Deterioration in Hospitalized Adult Patients with Hematologic Malignancies Using a Neural Network Model.
Scott Hu, Deborah J. L. Wong, Ning Li, Jane C. Deng> ;Plos One. 2016 Aug 17
13 citations
Prognostic significance of infections in critically ill adult patients with acute liver injury: a retrospective cohort study
Alexander Zider, Radhika Zopey, Ronak Garg, Xiaoyan Wang, Tisha Wang, Jane C. Deng> ;Liver International. 2016 Aug 1
55 citations
The administration of intranasal live attenuated influenza vaccine induces changes in the nasal microbiota and nasal epithelium gene expression profiles.
Y. Tarabichi, Kelvin Li, Scott Hu, C. Nguyen, Xiaoyan Wang, David Elashoff, K. Saira, Bryan C. Frank, Monika Bihan, Elodie Ghedin, Barbara A. Methé, Jane C. Deng> ;Microbiome. 2015 Dec 15
5 citations
Hypocretin Deficiency Associated with Narcolepsy Type 1 and Central Hypoventilation Syndrome in Neurosarcoidosis of the Hypothalamus.
Mary Catherine Mayo, Jane C. Deng, Jeffrey Albores, Michelle Zeidler, Ronald M. Harper, Alon Y. Avidan> ;Journal of Clinical Sleep Medicine. 2015 Sep 15
78 citations
Subsequent Infections in Survivors of Sepsis: Epidemiology and Outcomes
Tisha Wang, Ariss Derhovanessian, Sharon De Cruz, John A. Belperio, Jane C. Deng, Guy W. Soo Hoo> ;Journal of Intensive Care Medicine. 2014 Mar 1
78 citations
Hepcidin Induction by Pathogens and Pathogen-Derived Molecules Is Strongly Dependent on Interleukin-6
Richard Rodriguez, Chun Ling Jung, Victoria Gabayan, Jane C. Deng, Tomas Ganz, Elizabeta Nemeth, Yonca Bulut> ;Infection and Immunity. 2014 Feb 1
27 citations
Viral–bacterial interactions–therapeutic implications
Jane C. Deng> ;Influenza and Other Respiratory Viruses. 2013 Nov 1
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Hospital Affiliations

Veterans Affairs Ann Arbor Healthcare SystemAnn Arbor, Michigan