
Join to View Full Profile
1301 Central DrSanford, NC 27330
Phone+1 919-718-9512
Fax+1 919-718-9516
Dr. Little is on Doximity
As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.
- Gain access to free telehealth tools, such as our “call shielding” and one-way patient texting.
- Connect with colleagues in the same hospital or clinic.
- Read the latest clinical news, personalized to your specialty.
Education & Training
- University of Iowa Hospitals and ClinicsFellowship, Hematology and Medical Oncology, 1988 - 1991
- University of Iowa Hospitals and ClinicsResidency, Internal Medicine, 1986 - 1988
- Case Western Reserve University School of MedicineClass of 1985
Certifications & Licensure
- NC State Medical License 2019 - 2025
- OH State Medical License 2011 - 2021
- NY State Medical License 2006 - 2017
- MN State Medical License 1991 - 2011
- IA State Medical License 1985 - 1990
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Hematology
Clinical Trials
- Sickle Cell Disease and CardiovAscular Risk - Red Cell Exchange Trial (SCD-CARRE) Start of enrollment: 2020 Feb 26
Roles: Contact
Publications & Presentations
PubMed
- Blood-storage duration affects hematological and metabolic profiles in patients with sickle cell disease receiving transfusions.Matthew S Karafin, Abby L Grier, Ross M Fasano, Anton Ilich, David Wichlan
The Journal of Clinical Investigation. 2025-07-03 - Maternal sleep-associated hypoxemia is common during pregnancy in sickle cell disease: a retrospective review.Mofiyin A Obadina, Ada Chang, Iman Owens, Jane A Little
American Journal of Obstetrics & Gynecology MFM. 2025-06-01 - Real-world assessment of acute red cell exchange for stroke in sickle cell disease.Samuel R Wilson, Denis Noubouossie, Jane A Little, Matthew S Karafin
British Journal of Haematology. 2025-05-25
Press Mentions
- Post Roe, Pregnant SCD Patients Facing “Dire” RisksOctober 31st, 2022
Viewing the full profile is available to verified healthcare professionals only.
Find your profile and take control of your online presence: