JaneYYuMD

PubMed

• A Chronic Obstructive Pulmonary Disease Susceptibility Gene, FAM13A, Regulates Protein Stability of β-catenin.
  Jiang, Z.,Lao, T.,Qiu, W.,Polverino, F.,Gupta, K.,Guo, F.,Mancini, J. D.,Naing, Z. Z.,Cho, M. H.,Castaldi, P. J.,Sun, Y.,Yu, J.,Laucho-Contreras, M. E.,Kobzik, L.,Raby...> ;Am. J. Respir. Crit. Care Med.. 2016 Feb 11
• TSC2 Loss Increases Lysophosphatidylcholine Synthesis in Lymphangioleiomyomatosis.
  Priolo, C.,Ricoult, S. J.,Khabibullin, D.,Filippakis, H.,Yu, J.,Manning, B. D.,Clish, C.,Henske, E. P.> ;Am. J. Respir. Cell Mol. Biol.. 2015 Mar 18
• High-throughput drug screen identifies chelerythrine as a selective inducer of death in a TSC2-null setting.
  Medvetz, D.,Sun, Y.,Li, C.,Khabibullin, D.,Balan, M.,Parkhitko, A.,Priolo, C.,Asara, J. M.,Pal, S.,Yu, J.,Henske, E. P.> ;Mol. Cancer Res.. 2014 Sep 05
• Autophagy-Dependent Metabolic Reprogramming Sensitizes TSC2-Deficient Cells to the Antimetabolite 6-Aminonicotinamide.
  Parkhitko, A. A.,Priolo, C.,Coloff, J. L.,Yun, J.,Wu, J. J.,Mizumura, K.,Xu, W.,Malinowska, I. A.,Yu, J.,Kwiatkowski, D. J.,Locasale, J. W.,Asara, J. M.,Choi, A. M.,Fi...> ;Mol. Cancer Res.. 2013 Dec 04
• The mTORC1 Pathway Stimulates Glutamine Metabolism and Cell Proliferation by Repressing SIRT4.
  Csibi, A.,Fendt, S. M.,Li, C.,Poulogiannis, G.,Choo, A. Y.,Chapski, D. J.,Jeong, S. M.,Dempsey, J. M.,Parkhitko, A.,Morrison, T.,Henske, E. P.,Haigis, M. C.,Cantley, L...> ;Cell. 2013 May 9
• 28 citations
  MicroRNA-21 is induced by rapamycin in a model of tuberous sclerosis (TSC) and lymphangioleiomyomatosis (LAM).
  Anil J. Trindade, Douglas A. Medvetz, Nicole A. Neuman, Faina Myachina, Jane J. Yu, Carmen Priolo, Elizabeth P. Henske> ;Plos One. 2013 Mar 29
• Real-time monitoring of tumorigenesis, dissemination, & drug response in a preclinical model of lymphangioleiomyomatosis/tuberous sclerosis complex.
  Liu, F., Lunsford, E. P., Tong, J., Ashitate, Y., Gibbs, S. L., Yu, J., Choi, H. S., Henske, E. P., Frangioni, J. V.> ;PLoS ONE. 2012
• Autophagy: an 'Achilles' heel of tumorigenesis in TSC and LAM.
  Yu, J.,Parkhitko, A.,Henske, E. P.> ;Autophagy. 2011 Oct 15
• mTOR activation, lymphangiogenesis, and estrogen-mediated cell survival: the "perfect storm" of pro-metastatic factors in LAM pathogenesis.
  Yu, J.,Henske, E. P.> ;Lymphat Res Biol. 2010 Mar 20
• Mammalian target of rapamycin signaling and autophagy: roles in lymphangioleiomyomatosis therapy.
  Yu, J.,Parkhitko, A. A.,Henske, E. P.> ;Proc Am Thorac Soc. 2010 Feb 18
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