JaroslawPMaciejewskiMD

PubMed

• Safety and Efficacy of Pegcetacoplan in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria over 48 Weeks: 307 Open-Label Extension Study.
  Christopher J Patriquin, Andrija Bogdanovic, Morag Griffin, Richard J Kelly, Régis Peffault de Latour, Alexander Röth, Veena Selvaratnam, Jeffrey Szer, Mohammed Al-Adh...> ;Advances in Therapy. 2024 Apr 4
• Thrombocytosis and megakaryocyte changes associated with PRCA.
  Joelle Abdallah, Robert George Williams, Yusuf M Ozcan, Mutlu Mete, Carmelo Gurnari, Hussein Awada, Ganesh Raman, Mark David Orland, Weina Chen, Jaroslaw P Maciejewski...> ;Blood Advances. 2024 Apr 2
• Paroxysmal nocturnal hemoglobinuria-related thrombosis in the era of novel therapies: a 2043 patient/years analysis.
  Carmelo Gurnari, Simona Pagliuca, Naomi Kawashima, Yasuo Kubota, Valeria Visconte, Bhumika J Patel, Vikram Dhillon, Hussein Awada, Danai Dima, Fauzia Ullah, Ceylan Col...> ;Blood. 2024 Mar 21
• Ahemolytic PNH (white cell PNH): Clinical features and implications of a distinct phenotype of paroxysmal nocturnal haemoglobinuria.
  Zehra Tombul, Waled Bahaj, Merve Ozturk, Bhavisha Patel, Ahmet Toprak, Ibrahim Ibrahim, Weina Chen, Franklin Fuda, Olisaemeka D Ogbue, Carmelo Gurnari, Charles Parker,...> ;British Journal of Haematology. 2024 Mar 12
• Molecular and clinical analyses of PHF6 mutant myeloid neoplasia provide their pathogenesis and therapeutic targeting.
  Yasuo Kubota, Xiaorong Gu, Laila Terkawi, Juraj Bodo, Bartlomiej P Przychodzen, Hussein Awada, Nakisha Williams, Carmelo Gurnari, Naomi Kawashima, Mai Aly, Arda Durmaz...> ;Nature Communications. 2024 Feb 28
• 1 citations
  Splenic irradiation for myelofibrosis prior to hematopoietic cell transplantation: A global collaborative analysis.
  Nico Gagelmann, Gabriela S Hobbs, Edoardo Campodonico, Grzegorz Helbig, Polona Novak, Thomas Schroeder, Artur Schneider, Christina Rautenberg, Hans Christian Reinhardt...> ;American Journal of Hematology. 2024 May 1
• Author Correction: Molecular patterns identify distinct subclasses of myeloid neoplasia.
  Tariq Kewan, Arda Durmaz, Waled Bahaj, Carmelo Gurnari, Laila Terkawi, Hussein Awada, Olisaemeka D Ogbue, Ramsha Ahmed, Simona Pagliuca, Hassan Awada, Yasuo Kubota, Mi...> ;Nature Communications. 2024 Feb 8
• 1 citations
  Splenectomy outcomes in immune cytopenias: Treatment outcomes and determinants of response.
  Waled Bahaj, Tariq Kewan, Ramsha Ahmed, Danai Dima, Nakisha Willimas, Arda Durmaz, Valeria Visconte, Sara M Maskal, Carmelo Gurnari, Rosenblatt Steven, Jaroslaw P Maci...> ;Journal of Internal Medicine. 2024 Feb 1
• 2 citations
  Deciphering treatment patterns in non-severe/moderate aplastic anemia: an international observational study.
  Bruno Fattizzo, Carmelo Gurnari, Giulio Cassanello, Marta Bortolotti, Hussein Awada, Sabrina Giammarco, Dario Consonni, Simona Sica, Shreyans Gandhi, Roochi Trikha, Jo...> ;Leukemia. 2023 Dec 1
• 2 citations
  Genomics of deletion 7 and 7q in myeloid neoplasm: from pathogenic culprits to potential synthetic lethal therapeutic targets.
  Minako Mori, Yasuo Kubota, Arda Durmaz, Carmelo Gurnari, Charnise Goodings, Vera Adema, Ben Ponvilawan, Waled S Bahaj, Tariq Kewan, Thomas LaFramboise, Manja Meggendor...> ;Leukemia. 2023 Oct 1
• 1 citations
  Novel scheme for defining the clinical implications of TP53 mutations in myeloid neoplasia.
  Waled Bahaj, Tariq Kewan, Carmelo Gurnari, Arda Durmaz, Ben Ponvilawan, Ishani Pandit, Yasuo Kubota, Olisaemeka D Ogbue, Misam Zawit, Yazan Madanat, Taha Bat, Suresh K...> ;Journal of Hematology & Oncology. 2023 Aug 3
• 6 citations
  Clonal evolution in aplastic anemia: failed tumor surveillance or maladaptive recovery?
  Carmelo Gurnari, Simona Pagliuca, Jaroslaw P Maciejewski> ;Leukemia & Lymphoma. 2023 Jun 25
• Applicability of 2022 classifications of acute myeloid leukemia in the real-world setting.
  Enrico Attardi, Arianna Savi, Beatrice Borsellino, Alfonso Piciocchi, Marta Cipriani, Tiziana Ottone, Emiliano Fabiani, Mariadomenica Divona, Serena Travaglini, Maria ...> ;Blood Advances. 2023 Sep 12
• 4 citations
  Leukemia relapse via genetic immune escape after allogeneic hematopoietic cell transplantation.
  Simona Pagliuca, Carmelo Gurnari, Colin Hercus, Sébastien Hergalant, Sanghee Hong, Adele Dhuyser, Maud D'Aveni, Alice Aarnink, Marie Thérèse Rubio, Pierre Feugier, Fra...> ;Nature Communications. 2023 May 31
• 2 citations
  Molecular patterns identify distinct subclasses of myeloid neoplasia.
  Tariq Kewan, Arda Durmaz, Waled Bahaj, Carmelo Gurnari, Laila Terkawi, Hussein Awada, Olisaemeka D Ogbue, Ramsha Ahmed, Simona Pagliuca, Hassan Awada, Yasuo Kubota, Mi...> ;Nature Communications. 2023 May 30
• Relationship of paroxysmal nocturnal hemoglobinuria (PNH) granulocyte clone size to disease burden and risk of major vascular events in untreated patients: results fro...
  David Dingli, Jaroslaw P Maciejewski, Loree Larratt, Ronald S Go, Britta Höchsmann, Ke Zu, Philippe Gustovic, Alexander D Kulagin> ;Annals of Hematology. 2023 Jul 1
• 1 citations
  New approaches to idiopathic neutropenia in the era of clonal hematopoiesis.
  Tariq Kewan, Waled S Bahaj, Carmelo Gurnari, Valeria Visconte, Jaroslaw P Maciejewski, Olisaemeka D Ogbue> ;Experimental Hematology & Oncology. 2023 Apr 28
• Transplantation Referral Patterns for Patients with Newly Diagnosed Higher-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia at Academic and Community Sites in...
  Benjamin Tomlinson, Marcos de Lima, Christopher R Cogle, Michael A Thompson, David L Grinblatt, Daniel A Pollyea, Rami S Komrokji, Gail J Roboz, Michael R Savona, Mikk...> ;Transplantation and Cellular Therapy. 2023 Jul 1
• 4 citations
  IPSS-M in myelodysplastic neoplasms arising from aplastic anemia and paroxysmal nocturnal hemoglobinuria.
  Carmelo Gurnari, Pedro Henrique Prata, Luiz Fernando B Catto, Arda Durmaz, Lise Larcher, Marie Sebert, Vincent Allain, Tariq Kewan, Simona Pagliuca, Andre L Pinto, Mar...> ;Blood. 2023 Jun 22
• 2 citations
  Leukemia relapse via genetic immune escape after allogeneic hematopoietic cell transplantation.
  Simona Pagliuca, Carmelo Gurnari, Colin Hercus, Sébastien Hergalant, Sanghee Hong, Adele Dhuyser, Maud D'Aveni, Alice Aarnink, Marie Thérèse Rubio, Pierre Feugier, Fra...> ;Research Square. 2023 Apr 5
• 1 citations
  The clinicopathologic significance of NPM1 mutation and ability to detect mutated NPM1 by immunohistochemistry in non-AML myeloid neoplasms.
  Hatem Kaseb, Valeria Visconte, Daniel S Socha, Genevieve M Crane, Lisa Durkin, James R Cook, Jaroslaw P Maciejewski, Eric D Hsi, Heesun J Rogers> ;Genes, Chromosomes & Cancer. 2023 Oct 1
• 3 citations
  Utility of targeted gene sequencing to differentiate myeloid malignancies from other cytopenic conditions.
  Amy E DeZern, Johannes B Goll, R Coleman Lindsley, Rafael Bejar, Steffanie H Wilson, Donnie Hebert, Joachim Deeg, Ling Zhang, Steven Gore, Tareq Al Baghdadi, Jaroslaw ...> ;Blood Advances. 2023 Jul 25
• 9 citations
  Impact of TP53 on outcome of patients with myelofibrosis undergoing hematopoietic stem cell transplantation.
  Nico Gagelmann, Anita Badbaran, Rachel B Salit, Thomas Schroeder, Carmelo Gurnari, Simona Pagliuca, Victoria Panagiota, Christina Rautenberg, Bruno Cassinat, Felicitas...> ;Blood. 2023 Jun 8
• 2 citations
  A multimodal analysis of genomic and RNA splicing features in myeloid malignancies.
  Arda Durmaz, Carmelo Gurnari, Courtney E Hershberger, Simona Pagliuca, Noah Daniels, Hassan Awada, Hussein Awada, Vera Adema, Minako Mori, Ben Ponvilawan, Yasuo Kubota...> ;Iscience. 2023 Mar 17
• 2 citations
  Novel Scheme for Defining the Clinical Implications of TP53 Mutations in Myeloid Neoplasia.
  Waled Bahaj, Tariq Kewan, Carmelo Gurnari, Arda Durmaz, Ben Ponvilawan, Ishani Pandit, Yasuo Kubota, Olisaemeka D Ogbue, Misam Zawit, Yazan Madanat, Taha Bat, Suresh K...> ;Research Square. 2023 Mar 9
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Journal Articles

• Germline Loss of Function SAMD9 and SAMD9L Alterations in Adult Myelodysplastic Syndromes  
  Samuel Li, Mikkael A Sekeres, Jaroslaw P Maciejewski, Rabi Hanna, Blood
• Mutational Landscape of myelodysplastic/myeloproliferative Neoplasm – Unclassifiable (MDS/MPN-U)  
  Aziz Nazha, Rami S Komrokji, Andrew Sochacki, Mikkael A Sekeres, Prithviraj Bose, Courtney D DiNardo, Hagop M Kantarjian, Srdan Verstovsek, Sanam Loghavi, Jaroslaw P M..., Blood

Abstracts/Posters

• Mutational Type and Configuration of an Individual Gene May Differentially Impact the Clinical and Phenotypic Features
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Eltrombopag Creates a Transient Chemical Phenocopy of TET2 Loss of Function That Contributes to Hematopoietic Precursor ExpansionClinically Relevant Abstract
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Predicting Response to Hypomethylating Agents in Patients with Myelodysplastic Syndromes (MDS) Using Artificial Intelligence (AI)
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Pattern of Somatic Mutation Changes from Diagnosis to Relapse Following Allogeneic Hematopoietic Cell Transplantation (alloHCT) for Acute Myeloid Leukemia (AML) and My...
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• ANKRD26 Coding Variants Presenting with Giant Platelets and a Predisposition to Myeloid Neoplasia
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Genetics of Monosomy 7 and Del(7q) in MDS Informs Potential Therapeutic Targets
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Interactions between Donor Activating Killer Immunoglobulin-like Receptors (KIRs) and Somatic Mutations and Their Association with Outcomes after Allogeneic Hematopoie...
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• TET2 Loss Accelerates Leukemogenesis By Disrupting Mismatch Repair Proteins
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• TET Dioxygenase Inhibition As a Therapeutic Strategy in TET2 Mutant Myeloid Neoplasia
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Molecular Characterization of Leukemia Evolving from Paroxysmal Nocturnal Hemoglobinuri
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• CUL1: Novel Therapeutic Target in Myeloid Neoplasms Harboring -7/Del(7q)
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Large Granular Lymphocytic Leukemia Coexists with Clonal Hematopoiesis of Indeterminate PotentialClinically Relevant Abstract
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Geno-Clinical Model for the Diagnosis of Bone Marrow Myeloid Neoplasms
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Clonal Cytopenias of Undetermined Significance Are Common in Cytopenic Adults Evaluated for MDS in the National MDS Study
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Hotspot U2AF1 Mutations Determine Missplicing Selectivity: Novel Mechanisms Altering Splicing Factors
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Impact and Outcomes of RAS gene Mutations in Core Binding Factor Acute Myeloid Leukemia
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Fatty Acid Binding Protein FABP5: A Novel Therapeutic Target in Acute Myeloid Leukemia
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• A Single Arm, Phase II Study of Eltrombopag to Enhance Platelet Count Recovery in Older Patients with Acute Myeloid Leukemia (AML) Undergoing Remission Induction Therapy
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Can Monosomy 7 be Targeted By Next Generation Cereblon-Modulating Agents?
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Combined Treatment with Lenalidomide and Epoetin Alfa Leads to Durable Responses in Patients with Epo-Refractory, Lower Risk Non-Deletion 5q [Del(5q)] MDS: Final Resul...
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Integrated Analysis of Copy-Number Alterations and Gene Mutations in 2,000 Patients with Myeloid Neoplasms
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Feedback Responses of the Pyrimidine Metabolism Network Mediate Resistance to Decitabine and 5-Azacytidine
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Mutational Patterns and Clonal Architecture of Therapy-Related Acute Myeloid Leukemia
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Long-Term Experience with Large Granular Lymphocytic Leukemia Evolving after Solid Organ and Hematopoietic Stem Cell Transplantation
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Novel Molecular Pathogenesis and Therapeutic Target in Acute Erythroid Leukemia
  Jaroslaw P. Maciejewski, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
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