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Jason Merker, MD, Pathology, Chapel Hill, NC, University of North Carolina Hospitals

JasonDerekMerkerMDPhD

Pathology • Chapel Hill, NC

Molecular Genetics, Anatomic Pathology, Clinical Pathology

Associate Professor, Departments of Pathology and Laboratory Medicine & Genetics, UNC School of Medicine

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Education & Training

  • Stanford Health Care-Sponsored Stanford University
    Stanford Health Care-Sponsored Stanford UniversityResidency, Pathology-Anatomic and Clinical, 2008 - 2012
  • Stanford Health Care-Sponsored Stanford University
    Stanford Health Care-Sponsored Stanford UniversityResidency, Pathology-Anatomic and Clinical, 2005 - 2007
  • University of North Carolina School of Public Health
    University of North Carolina School of Public HealthPh.D., Genetics, 1996 - 2005
  • University of North Carolina at Chapel Hill School of Medicine
    University of North Carolina at Chapel Hill School of MedicineClass of 2005
  • University of North Carolina at Chapel Hill
    University of North Carolina at Chapel HillB.S., Biology, Highest Honors, 1992 - 1996

Certifications & Licensure

  • NC State Medical License
    NC State Medical License 2018 - 2025
  • CA State Medical License
    CA State Medical License 2006 - 2020
  • American Board of Pathology Pathology - Clinical
  • American Board of Pathology Pathology - Molecular Genetic
  • American Board of Medical Genetics and Genomics Clinical Cytogenetics and Genomics

Awards, Honors, & Recognition

  • Inspector Excellence College of American Pathologists Inspector Recognition Program, 2015
  • Stanford Society of Physician Scholars 2010
  • Alpha Omega Alpha Honor Medical Society 2004
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Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Efficacy and safety of midostaurin in patients with advanced systemic mastocytosis: 10-year median follow-up of a phase II trial  
    DeAngelo DJ, George TI, Linder A, Langford C, Perkins C, Ma J, Westervelt P, Merker JD, Berube C, Coutre S, Liedtke M, Medeiros B, Sternberg D, Dutreix C, Ruffie PA, C..., Leukemia, 1/1/2018
  • Long-read genome sequencing identifies causal structural variation in a Mendelian disease  
    Merker JD, Wenger AM, Sneddon T, Grove M, Zappala Z, Fresard L, Waggott D, Utiramerur S, Hou Y, Smith KS, Montgomery SB, Wheeler M, Buchan JG, Lambert CC, Eng KS, Hick..., Genet Med, 1/1/2018
  • ClinGen Cancer Somatic Working Group - standardizing and democratizing access to cancer molecular diagnostic data to drive translational research  
    Madhavan S, Ritter D, Micheel C, Rao S, Roy A, Sonkin D, McCoy M, Griffith M, Griffith OL, McGarvey P, Kulkarni S, on behalf of the ClinGen Somatic Working Group (Merk..., Pac Symp Biocomput, 1/1/2018
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Books/Book Chapters

  • Molecular Pathology in Clinical Practice 
    Chapter: T-Cell Lymphomas. 
    Page 603 - 614Merker JD, Arber DAEditors: Leonard DGB.Edition 2nd,2016
  • Molecular Diagnostics. 
    Chapter: Molecular diagnostics of hematopoietic disorders. 
    Page 243 - 260Merker JD, Arber DAEditors: Grody WW, Nakamura RM, Kiechle FL, Strom CM.2010

Lectures

  • How to select an NGS panel 
    King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia - 1/21/2017
  • NGS: CAP checklist and resources 
    King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia - 1/21/2017
  • Overview of NGS technology: possibilities and limitations 
    King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia - 1/21/2017
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Other

  • Charting the Course for Precision Medicine: Adopting consensus analytical standards and streamlining approval pathways for post-market modifications for NGS tests in o... 
    Contributors: Aisner D, Averbuch S, Duncan H, Ferris A, Flaherty KT, Iafrate AJ, Kalamegham R, Kowack E, Lasiter L, Merker J, Schneider E, Stewart M, Tanzella K, Thomae M, Friends of Cancer Research/Alexandria
    1/1/2017
  • Use of quantitative PCR in the monitoring of patients with chronic myelogenous leukemia. 
    Merker JD, NewsPath
    http://www.cap.org/apps/docs/newspath/0902/use_of_quantitative_pcr.pdf
    College of American Pathologists - 1/1/2009
  • Screening for Lynch syndrome by microsatellite instability analysis and immunohistochemistry. 
    Merker JD, NewsPath
    http://www.cap.org/apps/docs/newspath/0809/screening_for_lynch_syndrome.pdf
    College of American Pathologists - 1/1/2008

Authored Content

  • Proficiency Testing of Standardized Samples Shows High Interlaboratory Agreement for Clinical Next Generation Sequencing–Based Hematologic Malignancy Assays with Survey Material–Specific Differences in Variant FrequenciesJanuary 2020
  • Proficiency Testing of Standardized Samples Shows High Interlaboratory Agreement for Clinical Next Generation Sequencing–Based Hematologic Malignancy Assays with Survey Material–Specific Differences in Variant FrequenciesJanuary 2020

Press Mentions

  • Benchmarking Workflows to Assess Performance and Suitability of Germline Variant Calling Pipelines in Clinical Diagnostic Assays
    Benchmarking Workflows to Assess Performance and Suitability of Germline Variant Calling Pipelines in Clinical Diagnostic AssaysFebruary 24th, 2021
  • Liquid Biopsies Not Ready for Prime Time
    Liquid Biopsies Not Ready for Prime TimeMarch 5th, 2018
  • Researchers Use Long-Read Genome Sequencing for First Time in a Patient
    Researchers Use Long-Read Genome Sequencing for First Time in a PatientJune 22nd, 2017

Hospital Affiliations

Dr. Jason Merker, Dr. Jason Merker, MD, Dr. J Merker, Dr. Jason Derek Merker