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Office
555 Mission Bay Blvd South
San Francisco, CA 94158Phone+1 415-502-3119- Is this information wrong?
Summary
- I am a cardiologist and myocyte biologist. My clinical focus is cardio-oncology (the cardiovascular care of cancer patients and cancer survivors). My basic and translational NIH-funded laboratory addresses myocardial responses to various stresses including hypoxia, aging and toxins. Over the last several years, given my clinical interest in cardio-oncology, my laboratory focus has been in delineating the mechanistic underpinnings of cardiovascular toxicities from novel targeted cancer therapies. I believe because of the targeted nature of the toxicities, cardio-oncology can provide insights into novel signaling pathways that are relevant in human cardiovascular biology and pathology.
At University of California, San Francisco (UCSF), I am the William Grossman Distinguished Professor of Cardiology and Associate Professor in Residence and Founding Chief of a new section focused on Cardio-Oncology and Immunology. I work closely with cardiologists and oncologists, basic and translational researchers and clinicians locally, nationally and internationally. I have multiple collaborations with industry and regulatory bodies (including the US FDA). In 2019, I was named the first chair of the American Heart Association (AHA) cardio-oncology subcommittee. At Vanderbilt and UCSF, I established a Graduate Medical Education (GME) approved fellowship training the next generation of physician-scientists in the field of cardio-oncology. I am an elected member of American Society of Clinical Investigation (ASCI).
Education & Training
- Harvard Medical School/Dana-Farber Cancer InstitutePost-Doctoral Fellowship, Molecular Biology, , 2007 - 2014
- Brigham and Women's HospitalFellowship, Cardiovascular Disease, 2004 - 2007
- Johns Hopkins UniversityResidency, Internal Medicine, 2001 - 2004
- Uconn School Of MedicineClass of 2001
Certifications & Licensure
- CA State Medical License 2021 - 2025
- TN State Medical License 2014 - 2023
- AL State Medical License 2020 - 2020
- MA State Medical License 2004 - 2015
Clinical Trials
- Cardiac Fibrosis by CMR in Patients With Cancer Start of enrollment: 2013 Mar 01
- Detection of Cardiac Fibrosis in Patients With Lymphoma Start of enrollment: 2012 Mar 01
Publications & Presentations
PubMed
- Clonal Hematopoiesis and Inflammation in the VasculaturE (CHIVE): a prospective, longitudinal cohort and biorepository.Morgan L Shannon, Jonathan Brett Heimlich, Sydney Olson, Ariana Debevec, Zachary Copeland, Ashwin Kishtagari, Caitlyn Vlasschaert, Christina A Snider, Alexander J Silv...> ;Blood Advances. 2024 Apr 12
- Clinical spectrum and evolution of immune-checkpoint inhibitors toxicities over a decade-a worldwide perspective.Paul Gougis, Floriane Jochum, Baptiste Abbar, Elise Dumas, Kevin Bihan, Bénédicte Lebrun-Vignes, Jean-Philippe Spano, Enora Laas, Judicael Hotton, Fabien Reyal, Anne-S...> ;Eclinicalmedicine. 2024 Apr 1
- Cardiovascular events reported in patients with B-cell malignancies treated with zanubrutinib.Richard R Furman, Constantine S Tam, Joe-Elie Salem, Aileen Cohen, Meng Zhang, Jun Zhang, Lipeng Chen, Han Ma, Javid J Moslehi, Christopher R Flowers, Jennifer R Brown> ;Blood Advances. 2024 Mar 19
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Lectures
- Cancer Immunotherapies in Myocarditis2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019
- What Cancer and Cancer Therapeutics Can do to Your Blood Vessels: Biologic Mechanisms and Role for Precision Medicine2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019
- Vasculo-Oncology 2019: An Emerging Field--Be a Part of It2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019
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Press Mentions
- Damar Hamlin’s Cardiac Arrest: What We Know and Don’t KnowJanuary 3rd, 2023
- Myocarditis in Cancer Patients Is Driven by Specific Immune CellsNovember 18th, 2022
- Immunotherapy-Related Myocarditis Linked to T Cells Targeting Cardiac-Specific AntigenNovember 17th, 2022
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Hospital Affiliations
- UCSF Medical CenterSan Francisco, California
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