JayWalterHeineckeMD

PubMed

• A targeted proteomics method for quantifying plasma apolipoprotein kinetics in individual mice using stable isotope labeling.
  Baohai Shao, Masami Shimizu-Albergine, Farah Kramer, Jenny E Kanter, Jay W Heinecke, Tomas Vaisar, Bettina Mittendorfer, Bruce W Patterson, Karin E Bornfeldt> ;Journal of Lipid Research. 2024 Mar 13
• 8 citations
  Helicobacter pylori outer membrane vesicles induce astrocyte reactivity through nuclear factor-κappa B activation and cause neuronal damage in vivo in a murine model.
  Esteban Palacios, Lorena Lobos-González, Simón Guerrero, Marcelo J Kogan, Baohai Shao, Jay W Heinecke, Andrew F G Quest, Lisette Leyton, Manuel Valenzuela-Valderrama> ;Journal of Neuroinflammation. 2023 Mar 9
• 1 citations
  Size matters: HDL particle populations and the risk of infection.
  Jay W Heinecke, W Sean Davidson> ;Nature Reviews. Cardiology. 2023 May 1
• 2 citations
  Extracellular vesicles from gastric epithelial GES-1 cells infected withpromote changes in recipient cells associated with malignancy.
  María Fernanda González, Renato Burgos-Ravanal, Baohai Shao, Jay Heinecke, Manuel Valenzuela-Valderrama, Alejandro H Corvalán, Andrew F G Quest> ;Frontiers in Oncology. 2022 Jan 1
• 8 citations
  CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins
  Masami Shimizu-Albergine, Debapriya Basu, Jenny E. Kanter, Farah Kramer, Vishal Kothari, Shelley Barnhart, Carissa Thornock, Adam E. Mullick, Noemie Clouet-Foraison, T...> ;The Journal of Clinical Investigation. 2021 Nov 15
• 8 citations
  Apolipoprotein A-I modulates HDL particle size in the absence of apolipoprotein A-II
  John T. Melchior, Scott E. Street, Tomas Vaisar, Rachel Hart, Jay Jerome, Zsuzsanna Kuklenyik, Noemie Clouet-Foraison, Carissa Thornock, Shimpi Bedi, Amy S. Shah, Jere...> ;Journal of Lipid Research. 2021 Jan 1
• 10 citations
  Niacin Increases Atherogenic Proteins in High-Density Lipoprotein of Statin-Treated Subjects.
  Graziella E. Ronsein, Tomas Vaisar, W. Sean Davidson, Karin E. Bornfeldt, Jeffrey L. Probstfield, Kevin D. O'Brien, Xue-Qiao Zhao, Jay W. Heinecke> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2021 Jun 17
• 12 citations
  Atherosclerosis Regression and Cholesterol Efflux in Hypertriglyceridemic Mice.
  Tatjana Josefs, Debapriya Basu, Tomas Vaisar, Britt Arets, Jenny E. Kanter, Lesley-Ann Huggins, Yunying Hu, Jianhua Liu, Noemie Clouet-Foraison, Jay W. Heinecke, Karin...> ;Circulation Research. 2021 Mar 19
• 3 citations
  Perimenopausal transdermal estradiol replacement reduces serum HDL cholesterol efflux capacity but improves cardiovascular risk factors.
  Tomas Vaisar, Jennifer L. Gordon, Jake Wimberger, Jay W. Heinecke, Alan L. Hinderliter, David R. Rubinow, Susan S. Girdler, Katya B. Rubinow> ;Journal of Clinical Lipidology. 2021 Jan 1
• 11 citations
  Association of apolipoprotein C3 with insulin resistance and coronary artery calcium in patients with type 1 diabetes.
  Teresa Buckner, Baohai Shao, Robert H. Eckel, Jay W. Heinecke, Karin E. Bornfeldt, Janet K. Snell-Bergeon> ;Journal of Clinical Lipidology. 2021 Jan 1
• 35 citations
  Diabetes Impairs Cellular Cholesterol Efflux From ABCA1 to Small HDL Particles.
  Yi He, Graziella E. Ronsein, Chongren Tang, Gail P. Jarvik, W. Sean Davidson, Vishal Kothari, Hyun Deok Song, Jere P. Segrest, Karin E. Bornfeldt, Jay W. Heinecke> ;Circulation Research. 2020 Oct 9
• 13 citations
  Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture
  Tomas Vaisar, Jie H Hu, Nathan Airhart, Kate Fox, Jay W. Heinecke, Roberto F. Nicosia, Ted R. Kohler, Zachary E. Potter, Gabriel M. Simon, Melissa M. Dix, Benjamin F. ...> ;Circulation Research. 2020 Sep 25
• Integrated Biomarker Discovery and Validation Implicates the Complement Pathway in Early Atherogenesis.
  Jay W. Heinecke, William C. Parks> ;Journal of the American College of Cardiology. 2020 Apr 28
• 102 citations
  Remnants of the Triglyceride-Rich Lipoproteins, Diabetes, and Cardiovascular Disease.
  Alan Chait, Henry N. Ginsberg, Tomas Vaisar, Jay W. Heinecke, Ira J. Goldberg, Karin E. Bornfeldt> ;Diabetes. 2020 Apr 1
• 35 citations
  High Concentration of Medium-Sized HDL Particles and Enrichment in HDL Paraoxonase 1 Associate With Protection From Vascular Complications in People With Long-standing...
  Tomas Vaisar, Jenny E. Kanter, Jake Wimberger, Angela Irwin, John Gauthier, Emily Wolfson, Vanessa Bahnam, I-Hsien Wu, Hetal Shah, Hillary A. Keenan, Carla J. Greenbau...> ;Diabetes Care. 2020 Jan 1
• 4 citations
  Does HDL (High-Density Lipoprotein) Play a Causal Role in Host Defenses Against Infection?
  Jay W. Heinecke> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2020 Jan 1
• 78 citations
  Anti-Inflammatory Effects of HDL (High-Density Lipoprotein) in Macrophages Predominate Over Proinflammatory Effects in Atherosclerotic Plaques.
  Panagiotis Fotakis, Vishal Kothari, David G. Thomas, Marit Westerterp, Matthew M. Molusky, Elissa Altin, Sandra Abramowicz, Nan Wang, Yi He, Jay W. Heinecke, Karin E. ...> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2019 Oct 3
• 61 citations
  Apolipoprotein AI) Promotes Atherosclerosis Regression in Diabetic Mice by Suppressing Myelopoiesis and Plaque Inflammation
  Tessa J. Barrett, Emilie Distel, Andrew J. Murphy, Jiyuan Hu, Michael S. Garshick, Yoscar Ogando, Jianhua Liu, Tomas Vaisar, Jay W. Heinecke, Jeffrey S. Berger, Ira J....> ;Circulation. 2019 Oct 1
• 63 citations
  Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes.
  Jenny E. Kanter, Baohai Shao, Farah Kramer, Shelley Barnhart, Masami Shimizu-Albergine, Tomas Vaisar, Mark J. Graham, Rosanne M. Crooke, Clarence R. Manuel, Rebecca A....> ;The Journal of Clinical Investigation. 2019 Oct 1
• 12 citations
  Albuminuria, the High-Density Lipoprotein Proteome, and Coronary Artery Calcification in Type 1 Diabetes Mellitus.
  Baohai Shao, Leila R. Zelnick, Jake Wimberger, Jonathan Himmelfarb, John D. Brunzell, W. Sean Davidson, Janet K. Snell-Bergeon, Karin E. Bornfeldt, Ian H. de Boer, Jay...> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2019 May 16
• 4 citations
  Apolipoprotein A1 Forms 5/5 and 5/4 Antiparallel Dimers in Human High-density Lipoprotein.
  Yi He, Hyun D Song, G M Anantharamaiah, M N Palgunachari, Karin E Bornfeldt, Jere P Segrest, Jay W Heinecke> ;Molecular & Cellular Proteomics. 2019 May 1
• 15 citations
  Genetic control of the mouse HDL proteome defines HDL traits, function, and heterogeneity.
  Nathalie Pamir, Calvin Pan, Deanna L. Plubell, Patrick M. Hutchins, Chongren Tang, Jake Wimberger, Angela Irwin, Thomas Q. de Aguiar Vallim, Jay W. Heinecke, Aldons J....> ;Journal of Lipid Research. 2019 Mar 1
• 80 citations
  Cholesterol Mass Efflux Capacity, Incident Cardiovascular Disease, and Progression of Carotid Plaque
  Steven Shea, James H. Stein, Neal W. Jorgensen, Robyn L. McClelland, Liana Tascau, Sandi Shrager, Jay W. Heinecke, Laurent Yvan-Charvet, Alan R. Tall> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2019 Jan 1
• 18 citations
  GM-CSF driven myeloid cells in adipose tissue link weight gain and insulin resistance via formation of 2-aminoadipate.
  Deanna L. Plubell, Alexandra M Fenton, Phillip A. Wilmarth, Paige Bergstrom, Yuqi Zhao, Jessica Minnier, Jay W. Heinecke, Xia Yang, Nathalie Pamir> ;Scientific Reports. 2018 Jul 31
• 15 citations
  Sex steroids mediate discrete effects on HDL cholesterol efflux capacity and particle concentration in healthy men.
  Katya B. Rubinow, Tomas Vaisar, Jing H. Chao, Jay W. Heinecke, Stephanie T. Page> ;Journal of Clinical Lipidology. 2018 Jul 1
• Join now to see all

Lectures

• Cholesterol-Carrying Lipoproteins and Cardiovascular Risk: New Guidelines and Beyond 
  ENDO 2019 - New Orleans, LA - 3/24/2019