
Jay M Lee MD
Adult General Thoracic Surgery, Minimally Invasive Thoracic Surgery, Pediatric Thoracic Surgery, Thoracic Surgical Oncology
Thoracic Surgical Oncologist | Clinical Trials in Lung Cancer | Biotech
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10833 Le Conte Ave., 64-128 CHSLos Angeles, CA 90095
Phone+1 310-794-7333
Fax+1 310-794-7333
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Summary
- Jay M. Lee, M.D., is the Surgical Director of the Thoracic Oncology Program, and Associate Professor of Surgery (Tenure Track) at the David Geffen School of Medicine at UCLA. He previously served as Chief, Division of Thoracic Surgery and Chief, Section of Thoracic Surgery for over a decade.
He received his medical degree from UCLA and training in General Surgery at Georgetown and Duke University Medical Centers. He completed a Thoracic Research Fellowship at Memorial Sloan Kettering Cancer Center and received Thoracic Surgery training at the Brigham and Women’s Hospital and Children’s Hospital Boston at Harvard Medical School.
Dr. Lee has published extensively in the field of thoracic oncology and has a funded research laboratory. His scientific effort has focused on translational trials involving investigator-initiated immunotherapy in human lung cancer and modulation of the immunosuppressive tumor microenvironment.
Dr. Lee is on the Steering Committee of several neoadjuvant or perioperative immunotherapy or targeted therapy trials in resectable non-small cell lung cancer (NSCLC) including LCMC3 (atezolizumab), CANOPY-N (canakinumab and/or pembrolizumab), NAUTIKA1 (alectinib, entrectinib, vemurafenib plus cobimetinib, pralsetinib, or stereotactic body radiation therapy plus atezolizumab),and GEOMETRY-N (capmatinib). Dr. Lee is also the Study Co-Chair for the Skyscraper-15 (phase 3 trial of adjuvant atezolzumab and tiragolumab). He is on the Scientific Advisory Committee for two Phase 3 Merck trials: Perioperative MK2870 (TROP2-ADC) and Adjvuant V940 (personalized mRNA cancer vaccine) with pembrolizumab. Dr. Lee is on the Executive Committee of the LCMC4/LEADER trial to define driver mutations in early stage NSCLC. Dr. Lee is an author on numerous peri-operative clinical trials including LCMC3 and IMPower 010 (adjuvant atezolizumab).
Dr. Lee is Board-certified by the American Board of Surgery (ABS) and the American Board of Thoracic Surgery (ABTS).
Education & Training
Mass General Brigham/Brigham and Women's Hospital/Children's HospitalFellowship, Thoracic Surgery - Independent, 2004 - 2006
Duke University HospitalResidency, Surgery, 2001 - 2004
Memorial Sloan Kettering Cancer CenterPost-Doctoral Fellowship, 1999 - 2001
MedStar Health Georgetown University (D.C.)Residency, Surgery, 1997 - 1999
David Geffen School of Medicine at UCLAClass of 1997
Certifications & Licensure
DC State Medical License 1999 - Present
CA State Medical License 2006 - 2028
NC State Medical License 2001 - 2017
MA State Medical License 2004 - 2016
VA State Medical License 1998 - 2016
American Board of Surgery Surgery
American Board of Thoracic Surgery Thoracic and Cardiac Surgery
Awards, Honors, & Recognition
- Regional Top Doctor Castle Connolly
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2014, 2016-2017
- CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2014, 2016-2017
Clinical Trials
- Vaccine Therapy in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer Start of enrollment: 2009 Feb 26
- Evaluation of Apricoxib (Selective Cyclooxygenase 2 Inhibition) in Modulating T Regulatory Cells of Patients With Early Stage Non-small Cell Lung Cancer Start of enrollment: 2011 Nov 01
Publications & Presentations
PubMed
- Stereotactic Body Radiation Therapy Utilization Trends for Stage I Non-Small Cell Lung Cancer.Sara Sakowitz, Haley I Tupper, Lawrence N Benjamin, Scott Oh, Tao He
Chest. 2026-04-01 - Updates on the Perioperative Management of Resectable Non-Small Cell Lung Cancer.Stacey M Frumm, Narjust Florez, Jay M Lee, Julia K Rotow, Jamie E Chaft
Journal of the National Comprehensive Cancer Network. 2026-03-24 - The Impact of Neoadjuvant Chemoradiation Therapy on Non-Tumorous Barrett's Dysplasia of the Esophagus: A Multicenter Cohort Study.Vismaya S Bachu, Jay M Lee, Hanlin L Wang, Phillip Kozan, Melanie Ramirez
Journal of Clinical Medicine. 2025-12-30
Professional Memberships
- Member
- Member
- Member
- General Thoracic Surgical ClubMember
- International Association for the Study of Lung CancerMember
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