
Jay M Lee MD
Adult General Thoracic Surgery, Minimally Invasive Thoracic Surgery, Pediatric Thoracic Surgery, Thoracic Surgical Oncology
Thoracic Surgical Oncologist | Clinical Trials in Lung Cancer | Biotech
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UCLA Medical Center10833 Le Conte Ave., 64-128 CHSLos Angeles, CA 90095
Phone+1 310-794-7333
Fax+1 310-794-7333
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Summary
- Jay M. Lee, M.D., is the Surgical Director of the Thoracic Oncology Program, and Associate Professor of Surgery (Tenure Track) at the David Geffen School of Medicine at UCLA. He previously served as Chief, Division of Thoracic Surgery and Chief, Section of Thoracic Surgery for over a decade.
He received his medical degree from UCLA and training in General Surgery at Georgetown and Duke University Medical Centers. He completed a Thoracic Research Fellowship at Memorial Sloan Kettering Cancer Center and received Thoracic Surgery training at the Brigham and Women’s Hospital and Children’s Hospital Boston at Harvard Medical School.
Dr. Lee has published extensively in the field of thoracic oncology and has a funded research laboratory. His scientific effort has focused on translational trials involving investigator-initiated immunotherapy in human lung cancer and modulation of the immunosuppressive tumor microenvironment.
Dr. Lee is on the Steering Committee of several neoadjuvant or perioperative immunotherapy or targeted therapy trials in resectable non-small cell lung cancer (NSCLC) including LCMC3 (atezolizumab), CANOPY-N (canakinumab and/or pembrolizumab), NAUTIKA1 (alectinib, entrectinib, vemurafenib plus cobimetinib, pralsetinib, or stereotactic body radiation therapy plus atezolizumab),and GEOMETRY-N (capmatinib). Dr. Lee is also the Study Co-Chair for the Skyscraper-15 (phase 3 trial of adjuvant atezolzumab and tiragolumab). He is on the Scientific Advisory Committee for two Phase 3 Merck trials: Perioperative MK2870 (TROP2-ADC) and Adjvuant V940 (personalized mRNA cancer vaccine) with pembrolizumab. Dr. Lee is on the Executive Committee of the LCMC4/LEADER trial to define driver mutations in early stage NSCLC. Dr. Lee is an author on numerous peri-operative clinical trials including LCMC3 and IMPower 010 (adjuvant atezolizumab).
Dr. Lee is Board-certified by the American Board of Surgery (ABS) and the American Board of Thoracic Surgery (ABTS).
Education & Training
- Mass General Brigham/Brigham and Women's Hospital/Children's HospitalFellowship, Thoracic Surgery - Independent, 2004 - 2006
- Duke University HospitalResidency, Surgery, 2001 - 2004
- Memorial Sloan Kettering Cancer CenterPost-Doctoral Fellowship, 1999 - 2001
- MedStar Health Georgetown University (D.C.)Residency, Surgery, 1997 - 1999
- David Geffen School of Medicine at UCLAClass of 1997
Certifications & Licensure
- DC State Medical License 1999 - Present
- CA State Medical License 2006 - 2026
- NC State Medical License 2001 - 2017
- MA State Medical License 2004 - 2016
- VA State Medical License 1998 - 2016
- American Board of Surgery Surgery
- American Board of Thoracic Surgery Thoracic and Cardiac Surgery
Awards, Honors, & Recognition
- Regional Top Doctor Castle Connolly
- Super Doctor SuperDoctors.com
- Fellow (FACS) American College of Surgeons
Clinical Trials
- Vaccine Therapy in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer Start of enrollment: 2009 Feb 26
- Evaluation of Apricoxib (Selective Cyclooxygenase 2 Inhibition) in Modulating T Regulatory Cells of Patients With Early Stage Non-small Cell Lung Cancer Start of enrollment: 2011 Nov 01
Publications & Presentations
PubMed
- The Impact of the Tumor Microenvironment on the Effect of IL-1β Blockade in NSCLC: Biomarker Analyses from CANOPY-1 and CANOPY-N Trials.Benjamin J Solomon, Daniel S W Tan, Gilberto de Castro Jr, Manuel Cobo, Marina Chiara Garassino
Cancer Research Communications. 2025-04-01 - Correction: Girard et al. Comparative Efficacy of Neoadjuvant Nivolumab Plus Chemotherapy versus Conventional Comparator Treatments in Resectable Non-Small-Cell Lung C...Nicolas Girard, Mariam Besada, Basia Rogula, Stefano Lucherini, Lien Vo
Cancers. 2025-02-17 - 1 citationsNeoadjuvant, perioperative, or adjuvant immunotherapy in resectable non-small cell lung cancer: How do I choose? Importance of immune biomarkers and molecular testing.Jay M Lee
The Journal of Thoracic and Cardiovascular Surgery. 2024-10-01
Professional Memberships
- Member
- Member
- Member
- General Thoracic Surgical ClubMember
- International Association for the Study of Lung CancerMember
- Western Thoracic Surgical AssociationMember
- Society of University SurgeonsMember
- International Mesothelioma Interest GroupMember
- International Society for Minimally Invasive Cardiothoracic SurgeryMember
- International Thymic Malignancy Interest GroupMember
- Member
- Member
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