JayWarrenSchneiderMD

Cardiology • Jacksonville, FL

Assistant Professor, Internal Medicine, University of Texas Southwestern Medical Center, Southwestern Medical School

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Office
4500 San Pablo Road S
Jacksonville, FL 32224
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Education & Training

Brigham and Women's HospitalFellowship, Cardiovascular Disease, 1994 - 1997
Brigham and Women's HospitalResidency, Internal Medicine, 1989 - 1991
Yale School of MedicineClass of 1989

Certifications & Licensure

FL State Medical License 2021 - 2026
TX State Medical License 2004 - 2023
American Board of Internal Medicine Cardiovascular Disease

Publications & Presentations

PubMed

20 citations
Highly Efficient SARS-CoV-2 Infection of Human Cardiomyocytes: Spike Protein-Mediated Cell Fusion and Its Inhibition.
Chanakha K. Navaratnarajah, David R. Pease, Peter Halfmann, Biruhalem Taye, Alison Barkhymer, Kyle G. Howell, Jon E. Charlesworth, Trace A. Christensen, Yoshihiro Kawa...> ;Journal of Virology. 2021 Oct 6
Author Correction: Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs.
Jay W. Schneider, Saji Oommen, Muhammad Yasir Qureshi, Sean C. Goetsch, David R. Pease, Rhianna S. Sundsbak, Wei Guo, Mingming Sun, Han Sun, Hidehito Kuroyanagi, Denni...> ;Nature Medicine. 2021 Jun 2
47 citations
Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs.
Jay W. Schneider, Saji Oommen, Muhammad Yasir Qureshi, Sean C. Goetsch, David R. Pease, Rhianna S. Sundsbak, Wei Guo, Mingming Sun, Han Sun, Hidehito Kuroyanagi, Denni...> ;Nature Medicine. 2020 Nov 13
17 citations
Role of RB1 in human embryonic stem cell-derived retinal organoids
Canbin Zheng, Jay W. Schneider, Jenny Hsieh> ;Developmental Biology. 2020 Jun 15
21 citations
Polycystin-1 Assembles With Kv Channels to Govern Cardiomyocyte Repolarization and Contractility
Francisco Altamirano, Gabriele G. Schiattarella, Kristin M. French, Soo Young Kim, Felipe Engelberger, Sergii Kyrychenko, Elisa Villalobos, Dan Tong, Jay W. Schneider,...> ;Circulation. 2019 Sep 10
39 citations
Down Syndrome Critical Region 1 Gene, Rcan1, Helps Maintain a More Fused Mitochondrial Network.
Valentina Parra, Francisco Altamirano, Carolina Hernández-Fuentes, Dan Tong, Viktoriia Kyrychenko, David Rotter, Zully Pedrozo, Joseph A. Hill, Verónica Eisner, Sergio...> ;Circulation Research. 2018 Mar 16
7 citations
Priapism in a Fabry disease mouse model is associated with upregulated penile nNOS and eNOS expression
Xing Li Meng, Erland Arning, Mary Wight-Carter, Taniqua S. Day, Siamak Jabbarzadeh-Tabrizi, Shuyuan Chen, Robin J. Ziegler, Teodoro Bottiglieri, Jay W. Schneider, Seng...> ;Journal of Inherited Metabolic Disease. 2018 Mar 1
163 citations
Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing
Chengzu Long, Hui Li, Malte Tiburcy, Cristina Rodriguez-Caycedo, Viktoriia Kyrychenko, Huanyu Zhou, Yu Zhang, Yi Li Min, John M. Shelton, Pradeep P.A. Mammen, Norman Y...> ;Science Advances. 2018 Jan 1
68 citations
Functional correction of dystrophin actin binding domain mutations by genome editing.
Viktoriia Kyrychenko, Sergii Kyrychenko, Malte Tiburcy, John M. Shelton, Chengzu Long, Jay W. Schneider, Wolfram-Hubertus Zimmermann, Rhonda Bassel-Duby, Eric N. Olson> ;JCI Insight. 2017 Sep 21
24 citations
Retinoblastoma protein controls growth, survival and neuronal migration in human cerebral organoids.
Takeshi Matsui, Vanesa Nieto-Estévez, Sergii Kyrychenko, Jay W. Schneider, Jenny Hsieh> ;Development. 2017 Mar 15
278 citations
Doxorubicin Blocks Cardiomyocyte Autophagic Flux by Inhibiting Lysosome Acidification
Dan L. Li, Zhao V. Wang, Guanqiao Ding, Wei Tan, Xiang Luo, Alfredo Criollo, Min Xie, Nan Jiang, Herman I. May, Viktoriia Kyrychenko, Jay W. Schneider, Thomas G. Gille...> ;Circulation. 2016 Apr 26
58 citations
Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression
Cyndi R. Morales, Dan L. Li, Zully Pedrozo, Herman I. May, Nan Jiang, Viktoriia Kyrychenko, Geoffrey W Cho, Soo Young Kim, Zhao V. Wang, David Rotter, Beverly A. Rothe...> ;Science Signaling. 2016 Apr 5
15 citations
Isoxazole Alters Metabolites and Gene Expression, Decreasing Proliferation and Promoting a Neuroendocrine Phenotype in β-Cells.
Michael A. Kalwat, Zhimin Huang, Chonlarat Wichaidit, Kathleen McGlynn, Svetlana Earnest, Claudia Savoia, Elhadji M. Dioum, Jay W. Schneider, Michele R. Hutchison, Mel...> ;ACS Chemical Biology. 2016 Feb 10
8 citations
Pharmacological priming of adipose-derived stem cells promotes myocardial repair
Jana S. Burchfield, Ashley L Paul, Vishy Lanka, Wei Tan, Yongli Kong, Camille McCallister, Beverly A. Rothermel, Jay W. Schneider, Thomas G. Gillette, Joseph A. Hill> ;Journal of Investigative Medicine. 2016 Jan 1
55 citations
FoxO4 Promotes Early Inflammatory Response Upon Myocardial Infarction via Endothelial Arg1
Min Zhu, Sean C. Goetsch, Zhaoning Wang, Robert Luo, Joseph A. Hill, Jay W. Schneider, Sidney M. Morris, Zhi Ping Liu> ;Circulation Research. 2015 Nov 6
19 citations
Blocking hyperactive androgen receptor signaling ameliorates cardiac and renal hypertrophy in Fabry mice
Jin-Song Shen, Xing Li Meng, Mary Wight-Carter, Taniqua S. Day, Sean C. Goetsch, Sabrina Forni, Jay W. Schneider, Zhi Ping Liu, Raphael Schiffmann> ;Human Molecular Genetics. 2015 Jun 1
Very small "window of opportunity" for generating CO oxidation-active Aun on TiO2.
Tang, X.,Schneider, J.,Dollinger, A.,Luo, Y.,Wörz, A. S.,Judai, K.,Abbet, S.,Kim, Y. D.,Ganteför, G. F.,Fairbrother, D. H.,Heiz, U.,Bowen, K. H.,Proch, S.> ;Phys Chem Chem Phys. 2014 Mar 05
50 citations
Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration.
Sarvjeet Singh, Diana C. Canseco, Shilpa M. Manda, John M. Shelton, Rajendra R. Chirumamilla, Sean C. Goetsch, Qiu Ye, Robert D. Gerard, Jay W. Schneider, James A. Ric...> ;Proceedings of the National Academy of Sciences of the United States of America. 2014 Jan 7
109 citations
Activation of MRTF-A–dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing
Lissette S. Velasquez, Lillian B. Sutherland, Zhenan Liu, Frederick Grinnell, Kristine E. Kamm, Jay W. Schneider, Eric N. Olson, Eric M. Small> ;Proceedings of the National Academy of Sciences of the United States of America. 2013 Oct 15
Cation size effects in mixed-ion metaphosphate glasses: structural characterization by multinuclear solid state NMR spectroscopy.
Schneider J, Tsuchida J, Eckert H> ;Phys Chem Chem Phys. 2013-09-14
12 citations
Neural Stem Cells, Excited
Jenny Hsieh, Jay W. Schneider> ;Science. 2013 Mar 29
21 citations
Coupling hippocampal neurogenesis to brain pH through proneurogenic small molecules that regulate proton sensing G protein-coupled receptors.
Jay W. Schneider, Sean C. Goetsch, Xiuyu Leng, Sara Ludwig, Jamie Russell, Cui-Ping Yang, Qing Jun Zhang> ;ACS Chemical Neuroscience. 2012 Jul 18
28 citations
Targeting Native Adult Heart Progenitors with Cardiogenic Small Molecules
Jamie Russell, Sean C. Goetsch, Hector R. Aguilar, Doug E. Frantz, Jay W. Schneider> ;ACS Chemical Biology. 2012 Jun 15
1402 citations
Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
Masato Kato, Tina W. Han, Shanhai Xie, Kevin Y. Shi, Xinlin Du, Leeju C. Wu, Hamid Mirzaei, Elizabeth J. Goldsmith, Jamie Longgood, Jimin Pei, Nick V. Grishin, Douglas...> ;Cell. 2012 May 11
39 citations
Regulated expression of pH sensing G Protein-coupled receptor-68 identified through chemical biology defines a new drug target for ischemic heart disease.
Jamie Russell, Sean C. Goetsch, Hector R. Aguilar, Helen Coe, Xiang Luo, Ning Liu, Eva Van Rooij, Doug E. Frantz, Jay W. Schneider> ;ACS Chemical Biology. 2012 Jun 15
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Press Mentions

Model for Rare Cancer Results Instead in ObesityJanuary 11th, 2021
Science Saturday: Across Time, Place to Find Cures for Inherited Heart DiseasesDecember 22nd, 2020
Cellular Pathway of Genetic Heart Disease Similar to Neurodegenerative DiseaseNovember 13th, 2020
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