JefferyMKlcoMD

PubMed

• Functional characterization of cooperating MGA mutations in RUNX1::RUNX1T1 acute myeloid leukemia.
  Melvin E Thomas 3rd, Wenqing Qi, Michael P Walsh, Jing Ma, Tamara Westover, Sherif Abdelhamed, Lauren J Ezzell, Chandra Rolle, Emily Xiong, Wojciech Rosikiewicz, Beisi...> ;Leukemia. 2024 Mar 7
• 5G2 mutant mice model loss of a commonly deleted segment of chromosome 7q22 in myeloid malignancies.
  Jasmine C Wong, Kelley M Weinfurtner, Tamara Westover, Jangkyung Kim, Eric J Lebish, Maria Del Pilar Alzamora, Benjamin J Huang, Michael Walsh, Sherif Abdelhamed, Jing...> ;Leukemia. 2024 Mar 5
• Genomic and global gene expression profiling in pediatric and young adult acute leukemia with PICALM::MLLT10 Fusion.
  Jingqun Ma, Yen-Chun Liu, Rebecca K Voss, Jing Ma, Ajay Palagani, Elizabeth Caldwell, Wojciech Rosikiewicz, Maria Cardenas, Scott Foy, Masayuki Umeda, Mark R Wilkinson...> ;Leukemia. 2024 Mar 1
• tandem duplications in pediatric myelodysplastic syndrome and acute myeloid leukemia: implications for clinical screening and diagnosis.
  Barajas, J., Umeda, M., Contreras, L., Westover, T., Walsh, M., Xiong, E., Yang, C., Otero, B., Arribas-Layton, M., Abdelhamed, S., Song, G., Ma, X., Thomas Rd, M., Ma...> ;Haematologica. 2024 Feb 29
• Peptide-scFv antigen recognition domains effectively confer CAR T cell multiantigen specificity.
  Velasquez, P., Velasquez, P., Jaquelyn T Zoine, Kalyan Immadisetty, Jorge Ibanez-Vega, Sarah E Moore, Chris Nevitt, Unmesha Thanekar, Liqing Tian, Abbas Karouni, Peter...> ;Cell Reports. Medicine. 2024 Feb 20
• 5 citations
  Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors.
  Juan M Barajas, Milad Rasouli, Masayuki Umeda, Ryan Hiltenbrand, Sherif Abdelhamed, Rebecca Mohnani, Bright Arthur, Tamara Westover, Melvin E Thomas 3rd, Minoo Ashtian...> ;Blood. 2024 Feb 15
• Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines.
  Nishiguchi, G., Mascibroda, L., Young, S., Caine, E., Abdelhamed, S., Kooijman, J., Miller, D., Das, S., McGowan, K., Mayasundari, A., Shi, Z., Barajas, J., Hiltenbran...> ;Nature Communications. 2024 Jan 16
• 1 citations
  A new genomic framework to categorize pediatric acute myeloid leukemia.
  Masayuki Umeda, Jing Ma, Tamara Westover, Yonghui Ni, Guangchun Song, Jamie L Maciaszek, Michael Rusch, Delaram Rahbarinia, Scott Foy, Benjamin J Huang, Michael P Wals...> ;Nature Genetics. 2024 Feb 1
• Tandem Duplications in Pediatric MDS and AML: Implications for Clinical Screening and Diagnosis.
  Juan M Barajas, Masayuki Umeda, Lisett Contreras, Tamara Westover, Michael P Walsh, Emily Xiong, Chenchen Yang, Brittney Otero, Marc Arribas-Layton, Sherif Abdelhamed,...> ;Medrxiv. 2023 Nov 13
• Concurrent peripheral T-cell lymphoma and T-cell lymphoblastic leukemia/lymphoma with identical::fusion events.
  Mahsa Khanlari, Wei Wang, Yen-Chun Liu, Lu Wang, Jeffrey E Rubnitz, Stephanie Dixon, Brent A Orr, Zhongshan Cheng, Vidya Balagopal, Jeffery M Klco, Anelo, O.> ;Haematologica. 2024 Mar 1
• Functional Characterization of Cooperating MGA Mutations in RUNX1::RUNX1T1 Acute Myeloid Leukemia.
  Jeffery Klco, Melvin Thomas 3rd, Wenqing Qi, Michael Walsh, Jing Ma, Tamara Westover, Sherif Abdelhamed, Lauren Ezzell, Chandra Rolle, Emily Xiong, Wojciech Rosikiewic...> ;Research Square. 2023 Sep 22
• -positive acute leukemia with RAM and mixed T/megakaryocytic phenotype.
  Mahsa Khanlari, Lu Wang, Christine Y Bolen, Felipe Sebastian Bautista Otanez, Larissa V Furtado, Laura Key, Lisa Irwin, Wei Wang, Jeffery M Klco> ;Ejhaem. 2023 Aug 1
• 8 citations
  Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41.
  Claire C Homan, Michael W Drazer, Kai Yu, David M Lawrence, Jinghua Feng, Luis Arriola-Martinez, Matthew J Pozsgai, Kelsey E McNeely, Thuong Ha, Parvathy Venugopal, Pe...> ;Blood Advances. 2023 Oct 24
• Clinical and genomic characterization of an ATRA-insensitive acute promyelocytic leukemia variant with a FNDC3B::RARB fusion.
  Justin K Kirkham, Yen-Chun Liu, Scott G Foy, Jing Ma, Gabriela Gheorghe, Larissa V Furtado, Marcela I Popescu, Jeffery M Klco, Seth E Karol, Patrick R Blackburn> ;Genes, Chromosomes & Cancer. 2023 Oct 1
• Proposal of a new genomic framework for categorization of pediatric acute myeloid leukemia associated with prognosis.
  Masayuki Umeda, Jing Ma, Tamara Westover, Yonghui Ni, Guangchun Song, Jamie L Maciaszek, Michael Rusch, Delaram Rahbarinia, Scott Foy, Benjamin J Huang, Michael P Wals...> ;Research Square. 2023 May 29
• 1 citations
  Clinical impact of minimal residual disease in blood and bone marrow of children with acute myeloid leukemia.
  Seth E Karol, Elaine Coustan-Smith, Stanley Pounds, Lei Wang, Hiroto Inaba, Raul C Ribeiro, Ching-Hon Pui, Jeffery M Klco, Jeffrey E Rubnitz> ;Blood Advances. 2023 Jul 25
• 3 citations
  Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication.
  Yanling Liu, Jonathon Klein, Richa Bajpai, Li Dong, Quang Tran, Pandurang Kolekar, Jenny L Smith, Rhonda E Ries, Benjamin J Huang, Yi-Cheng Wang, Todd A Alonzo, Liqing...> ;Nature Communications. 2023 Apr 5
• 1 citations
  From PROTAC to inhibitor: Structure-guided discovery of potent and orally bioavailable BET inhibitors.
  Mladen Koravovic, Anand Mayasundari, Gordana Tasic, Fatemeh Keramatnia, Timothy R Stachowski, Huarui Cui, Sergio C Chai, Barbara Jonchere, Lei Yang, Yong Li, Xiang Fu,...> ;European Journal of Medicinal Chemistry. 2023 May 5
• 3 citations
  SAMHD1 single nucleotide polymorphisms impact outcome in children with newly diagnosed acute myeloid leukemia.
  Richard J Marrero, Xueyuan Cao, Huiyun Wu, Abdelrahman H Elsayed, Jeffery M Klco, Raul C Ribeiro, Jeffrey E Rubnitz, Xiaotu Ma, Soheil Meshinchi, Richard Aplenc, E And...> ;Blood Advances. 2023 Jun 13
• 21 citations
  Engineering naturally occurring CD7- T cells for the immunotherapy of hematological malignancies.
  Velasquez, P., Velasquez, P., Abdullah Freiwan, Jaquelyn T Zoine, Jeremy Chase Crawford, Abishek Vaidya, Stefan A Schattgen, Jacquelyn A Myers, Sagar L Patil, Mahsa Kh...> ;Blood. 2022 Dec 22
• 1 citations
  Description of a novel subtype of acute myeloid leukemia defined by recurrent CBFB insertions.
  Georgina L Ryland, Masayuki Umeda, Linda Holmfeldt, Sören Lehmann, Morten Krogh Herlin, Jing Ma, Mahsa Khanlari, Jeffrey E Rubnitz, Rhonda E Ries, Hansen J Kosasih, Pa...> ;Blood. 2023 Feb 16
• 57 citations
  Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia.
  Eric J Duncavage, Adam Bagg, Robert P Hasserjian, Courtney D DiNardo, Lucy A Godley, Ilaria Iacobucci, Siddhartha Jaiswal, Luca Malcovati, Alessandro M Vannucchi, Keyu...> ;Blood. 2022 Nov 24
• 15 citations
  Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia.
  Benjamin J Huang, Jenny L Smith, Jason E Farrar, Yi-Cheng Wang, Masayuki Umeda, Rhonda E Ries, Amanda R Leonti, Erin Crowgey, Scott N Furlan, Katherine Tarlock, Marcos...> ;Nature Communications. 2022 Sep 19
• 5 citations
  Mutant Samd9l expression impairs hematopoiesis and induces bone marrow failure in mice.
  Sherif Abdelhamed, Melvin E Thomas 3rd, Tamara Westover, Masayuki Umeda, Emily Xiong, Chandra Rolle, Michael P Walsh, Huiyun Wu, Jason R Schwartz, Virginia Valentine, ...> ;The Journal of Clinical Investigation. 2022 Nov 1
• 26 citations
  Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia.
  Masayuki Umeda, Jing Ma, Benjamin J Huang, Kohei Hagiwara, Tamara Westover, Sherif Abdelhamed, Juan M Barajas, Melvin E Thomas, Michael P Walsh, Guangchun Song, Liqing...> ;Blood Cancer Discovery. 2022 May 5
• Join now to see all