JeffreyScottBarrettMD

Emergency Medicine • Philadelphia, PA

Associate Professor, Emergency Medicine, Temple University School of Medicine

Join to view full profile

Dr. Barrett is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Barrett's full profile

Already have an account?

Office
3401 N Broad St
Philadelphia, PA 19140
Phone+1 215-707-5030
Is this information wrong?

Education & Training

Temple University HospitalResidency, Emergency Medicine, 1999 - 2002
Rutgers Robert Wood Johnson Medical SchoolClass of 1999

Certifications & Licensure

PA State Medical License 2000 - 2024
NJ State Medical License 2002 - 2003
American Board of Emergency Medicine Emergency Medicine

Publications & Presentations

PubMed

2 citations
Time to Expect More From Pharmacometrics.
Jeffrey S. Barrett> ;Clinical Pharmacology and Therapeutics. 2020 Dec 1
11 citations
A Quantitative Systems Pharmacology Model of Gaucher Disease Type 1 Provides Mechanistic Insight Into the Response to Substrate Reduction Therapy With Eliglustat.
Ruth E. Abrams, Chanchala D. Kaddi, Mengdi Tao, Randolph J Leiser, Giulia Simoni, Federico Reali, John E. Tolsma, Paul Jasper, Zachary van Rijn, Jing Li, Bradley Niesn...> ;CPT. 2020 Jul 1
1 citations
Perspective on Data-Sharing Requirements for the Necessary Evolution of Drug Development.
Jeffrey S. Barrett> ;Journal of Clinical Pharmacology. 2020 Jun 1
1 citations
Asking More of Our EHR Systems to Improve Outcomes for Pediatric Patients.
Jeffrey S. Barrett> ;Frontiers in Pharmacology. 2020 Mar 12
From Patient to Molecule: In Pursuit of Universal Treatments for TB.
Penny M. Heaton, Jeffrey S. Barrett> ;Clinical and Translational Science. 2020 Mar 1
8 citations
Pediatric Extrapolation in Type 2 Diabetes: Future Implications of a Workshop.
Jeffrey S. Barrett, Christina Bucci-Rechtweg, S.Y. Amy Cheung, Margaret Gamalo-Siebers, Sebastian Haertter, Janina Karres, Jan Marquard, Yeruk Mulugeta, Cecile Ollivie...> ;Clinical Pharmacology and Therapeutics. 2020 Feb 4
4 citations
Real-World Data: An Unrealized Opportunity in Global Health?
Jeffrey S. Barrett, Penny M. Heaton> ;Clinical Pharmacology and Therapeutics. 2019 Jul 1
7 citations
A Pediatric Covariate Function for CYP3A-Mediated Midazolam Clearance Can Scale Clearance of Selected CYP3A Substrates in Children.
Janneke M. Brussee, Elke H. J. Krekels, Elisa A. M. Calvier, Semra Palic, Amin Rostami-Hodjegan, Meindert Danhof, Jeffrey S. Barrett, Saskia N. de Wildt, Catherijne A....> ;The AAPS Journal. 2019 Jun 27
21 citations
Challenges and Opportunities With Oncology Drug Development in China
Gaurav Bajaj, Manish Gupta, Hwei‐Gene Heidi Wang, Jeffrey S. Barrett, Matthew Tan, Katrin Rupalla, Richard Bertz, Jennifer Sheng> ;Clinical Pharmacology and Therapeutics. 2019 Feb 1
24 citations
Physiologically Based Pharmacokinetic Approach to Determine Dosing on Extracorporeal Life Support: Fluconazole in Children on ECMO.
Kevin M. Watt, Michael Cohen-Wolkowiez, Jeffrey S. Barrett, Michael Sevestre, Ping Zhao, Kim L. R. Brouwer, Andrea N. Edginton> ;CPT. 2018 Oct 1
20 citations
Characterization of Intestinal and Hepatic CYP3A-Mediated Metabolism of Midazolam in Children Using a Physiological Population Pharmacokinetic Modelling Approach
Janneke M. Brussee, Huixin Yu, Elke H. J. Krekels, Semra Palic, Margreke J. E. Brill, Jeffrey S. Barrett, Amin Rostami-Hodjegan, Saskia N. de Wildt, Catherijne A. J. K...> ;Pharmaceutical Research. 2018 Jul 30
20 citations
Quantitative Systems Pharmacology Modeling of Acid Sphingomyelinase Deficiency and the Enzyme Replacement Therapy Olipudase Alfa Is an Innovative Tool for Linking Path...
Chanchala D. Kaddi, Bradley Niesner, Rena Baek, Paul Jasper, John Pappas, John E. Tolsma, Jing Li, Zachary van Rijn, Mengdi Tao, Catherine Ortemann-Renon, Rachael East...> ;CPT. 2018 Jul 1
8 citations
Leveraging Big Data in Pediatric Development Programs: Proceedings From the 2016 American College of Clinical Pharmacology Annual Meeting Symposium.
Lily Yeruk Mulugeta, Lynne Yao, Diane R. Mould, Brian R. Jacobs, Jeffrey Florian, Brian Smith, Vikram Sinha, Jeffrey S. Barrett> ;Clinical Pharmacology and Therapeutics. 2018 Jul 1
24 citations
Higher Midazolam Clearance in Obese Adolescents Compared with Morbidly Obese Adults
Anne van Rongen, Margreke J. E. Brill, Janelle D. Vaughns, Pyry A. J. Välitalo, Eric P.A. van Dongen, Bert van Ramshorst, Jeffrey S. Barrett, Johannes N. van den Anker...> ;Clinical Pharmacokinetics. 2018 May 1
24 citations
Challenges and Opportunities in the Development of Medical Therapies for Pediatric Populations and the Role of Extrapolation
Jeffrey S. Barrett, Raafat Bishai, Christina Bucci-Rechtweg, Amy Cheung, Solange Corriol-Rohou, Sebastian Haertter, Angela Joubert James, Steven J. Kovacs, Jing Liu, D...> ;Clinical Pharmacology and Therapeutics. 2018 Mar 1
23 citations
Development of Drug Therapies for Newborns and Children: The Scientific and Regulatory Imperatives.
Yeruk Mulugeta, Anne Zajicek, Jeffrey S. Barrett, Hari Cheryl Sachs, Susan McCune, Vikram Sinha, Lynne Yao> ;Pediatric Clinics of North America. 2017 Dec 1
10 citations
Antiinflammatory effects of aprepitant coadministration with cART regimen containing ritonavir in HIV-infected adults
Sergei Spitsin, Pablo Tebas, Jeffrey S. Barrett, Vasiliki Pappa, Deborah Kim, Deanne Taylor, Dwight L. Evans, Steven D. Douglas> ;JCI Insight. 2017 Oct 5
8 citations
Linear-In-Flux-Expressions Methodology: Toward a Robust Mathematical Framework for Quantitative Systems Pharmacology Simulators.
Sean T. McQuade, Ruth E. Abrams, Jeffrey S. Barrett, Benedetto Piccoli, Karim Azer> ;Gene Regulation and Systems Biology. 2017 Jul 26
9 citations
A Quantitative Systems Pharmacology Platform to Investigate the Impact of Alirocumab and Cholesterol-Lowering Therapies on Lipid Profiles and Plaque Characteristics.
Jeffrey E Ming, Ruth E. Abrams, Derek W. Bartlett, Mengdi Tao, Tu Nguyen, Howard K. Surks, Katherine Kudrycki, Ananth Kadambi, Christina M. Friedrich, Nassim Djebli, B...> ;Gene Regulation and Systems Biology. 2017 Jun 22
67 citations
Safety, dosing, and pharmaceutical quality for studies that evaluate medicinal products (including biological products) in neonates
Robert M. Ward, Daniel K. Benjamin, Jeffrey S. Barrett, Karel Allegaert, Ronald J. Portman, Jonathan M. Davis, Mark A. Turner> ;Pediatric Research. 2017 May 1
55 citations
Exposure Matching for Extrapolation of Efficacy in Pediatric Drug Development
Yeruk Mulugeta, Jeffrey S. Barrett, Robert M. Nelson, Abel Tilahun Eshete, Alvina Mushtaq, Lynne Yao, Nicole Glasgow, Andrew E. Mulberg, Daniel Gonzalez, Dionna J. Gre...> ;Journal of Clinical Pharmacology. 2016 Nov 1
14 citations
Pharmacologic rationale for the NK1R antagonist, aprepitant as adjunctive therapy in HIV
Jeffrey S. Barrett, Sergei Spitsin, Ganesh S. Moorthy, Kyle Barrett, Kate C. Baker, Andrew A. Lackner, Florin Tulic, Angela Winters, Dwight L. Evans, Steven D. Douglas> ;Journal of Translational Medicine. 2016 May 26
23 citations
Use of Modeling and Simulation in the Design and Conduct of Pediatric Clinical Trials and the Optimization of Individualized Dosing Regimens.
Chris Stockmann, Jeffrey S. Barrett, Jessica K. Roberts, Catherine M.T. Sherwin> ;CPT. 2015 Nov 1
32 citations
Population pharmacokinetics of midazolam and its metabolites in overweight and obese adolescents
Anne van Rongen, Janelle D. Vaughns, Ganesh S. Moorthy, Jeffrey S. Barrett, Catherijne A. J. Knibbe, Johannes N. van den Anker> ;British Journal of Clinical Pharmacology. 2015 Nov 1
16 citations
Malabsorption blood test: Assessing fat absorption in patients with cystic fibrosis and pancreatic insufficiency
Maria R. Mascarenhas, John T. Mondick, Jeffrey S. Barrett, Martha D. Wilson, Virginia A. Stallings, Joan I. Schall> ;Journal of Clinical Pharmacology. 2015 Aug 1
Join now to see all

Hospital Affiliations

Temple University HospitalPhiladelphia, Pennsylvania