JeffreyADodgeDO

PubMed

• 10 citations
  Deciphering Binding Interactions of IL-23R with HDX-MS: Mapping Protein and Macrocyclic Dodecapeptide Ligands.
  Cristina Sayago, Isabel C. Gonzalez Valcarcel, Yuewei Qian, John Lee, Jorge Alsina-Fernandez, Nathan C. Fite, Juan J. Carrillo, Feiyu F. Zhang, Michael J. Chalmers, Je...> ;ACS Medicinal Chemistry Letters. 2018 Aug 1
• 13 citations
  Utilization of peptide phage display to investigate hotspots on IL-17A and what it means for drug discovery.
  Joey P. Ting, Frances Tung, Stephen Antonysamy, Stephen I. Wasserman, Spencer B. Jones, Feiyu F. Zhang, Alfonso Espada, Howard B. Broughton, Michael J. Chalmers, Micha...> ;Plos One. 2018 Jan 12
• 44 citations
  A Residue-Resolved Bayesian Approach to Quantitative Interpretation of Hydrogen-Deuterium Exchange from Mass Spectrometry: Application to Characterizing Protein-Ligand...
  Daniel J. Saltzberg, Howard B. Broughton, Riccardo Pellarin, Michael J. Chalmers, Alfonso Espada, Jeffrey Alan Dodge, Bruce D. Pascal, Patrick R. Griffin, Christine Hu...> ;The Journal of Physical Chemistry. B. 2017 Apr 20
• Corrigendum to "Structural features underlying raloxifene's biophysical interaction with bone matrix" [Bioorg. Med. Chem. 24 (2016) 759-767].
  Nicoletta Bivi, Haitao Hu, Balagopalakrishna Chavali, Michael J. Chalmers, Christopher T. Reutter, Gregory L. Durst, Anna Riley, Masahiko Sato, Matthew R. Allen, David...> ;Bioorganic & Medicinal Chemistry. 2016 Sep 15
• 22 citations
  Two-Site Evaluation of the Repeatability and Precision of an Automated Dual-Column Hydrogen/Deuterium Exchange Mass Spectrometry Platform.
  David J. Cummins, Alfonso Espada, Scott J. Novick, Manuel Molina-Martin, Ryan Edward Stites, Juan F. Espinosa, Howard B. Broughton, Devrishi Goswami, Bruce D. Pascal, ...> ;Analytical Chemistry. 2016 Jun 13
• 19 citations
  A Binding Site on IL-17A for Inhibitory Macrocycles Revealed by Hydrogen/Deuterium Exchange Mass Spectrometry.
  Alfonso Espada, Howard B. Broughton, Spencer B. Jones, Michael J. Chalmers, Jeffrey Alan Dodge> ;Journal of Medicinal Chemistry. 2016 Feb 18
• 14 citations
  Structural features underlying raloxifene’s biophysical interaction with bone matrix
  Nicoletta Bivi, Haitao Hu, Balagopalakrishna Chavali, Michael J. Chalmers, Christopher T. Reutter, Gregory L. Durst, Anna Riley, Masahiko Sato, Matthew R. Allen, David...> ;Bioorganic & Medicinal Chemistry. 2016 Feb 15
• 5 citations
  Discovery of synthetic Leishmania inhibitors by screening of a 2-arylbenzothiophene library.
  Vivian I. Bonano, Jenicer K.U. Yokoyama-Yasunaka, Danilo C. Miguel, Scott Alan Jones, Jeffrey Alan Dodge, Silvia R. B. Uliana> ;Chemical Biology & Drug Design. 2014 Mar 1
• 11 citations
  Hydrophobic Interactions Improve Selectivity to ERα for Ben-zothiophene SERMs.
  Michael J. Chalmers, Yong Wang, Scott J. Novick, Masahiko Sato, Henry Uhlman Bryant, Chahrzad Montrose-Rafizdeh, Patrick R. Griffin, Jeffrey Alan Dodge> ;ACS Medicinal Chemistry Letters. 2012 Mar 8
• 143 citations
  DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex
  Jun Zhang, Michael J. Chalmers, Keith R. Stayrook, Lorri L Burris, Yongjun Wang, Scott A. Busby, Bruce D. Pascal, Ruben D. Garcia-Ordonez, John B. Bruning, Monica A. I...> ;Nature Structural & Molecular Biology. 2011 May 1
• 20 citations
  Novel 3-Aryl Indoles as Progesterone Receptor Antagonists for Uterine Fibroids
  Timothy Ivo Richardson, Christian Alexander Clarke, Yu Kuo-Long, Ying K. Yee, Thomas J. Bleisch, Jose Eduardo Lopez, Scott Alan Jones, Norman Earle Hughes, Brian Steph...> ;ACS Medicinal Chemistry Letters. 2011 Feb 10
• Development of an HTS-Compatible Assay for Discovery of RORα Modulators Using AlphaScreen® Technology
  Monica A. Istrate, Timothy P. Spicer, Yan Wang, Jerrold A. Bernard, Leah M. Helvering, Wayne P. Bocchinfuso, Timothy Ivo Richardson, Richard W. Zink, Naresh Kumar, Cha...> ;Journal of Biomolecular Screening. 2011 Feb 1
• 48 citations
  Unique Ligand Binding Patterns Between Estrogen Receptor α and β Revealed by Hydrogen/Deuterium Exchange
  Susie Y. Dai, Thomas P. Burris, Jeffrey Alan Dodge, Chahrzad Montrose-Rafizadeh, Yong Wang, Bruce D. Pascal, Michael J. Chalmers, Patrick R. Griffin> ;Biochemistry. 2009 Oct 13
• 69 citations
  Prediction of the tissue-specificity of selective estrogen receptor modulators by using a single biochemical method.
  Susie Y. Dai, Michael J. Chalmers, John B. Bruning, Kelli S. Bramlett, Harold E. Osborne, Chahrzad Montrose-Rafizadeh, Robert J. Barr, Yong Wang, Minmin Wang, Thomas P...> ;Proceedings of the National Academy of Sciences of the United States of America. 2008 May 20
• 6 citations
  The selective oestrogen receptor modulator, LY362321 is not neuroprotective in a rat model of transient focal ischaemia
  Tracy D. Farr, Hilary V O Carswell, Denis J. McCann, Masahiko Sato, Henry Uhlman Bryant, Jeffrey Alan Dodge, I.M. Macrae> ;Journal of Neuroendocrinology. 2008 Mar 1
• 22 citations
  Benzopyrans as selective estrogen receptor β agonists (SERBAs). Part 5: Combined A- and C-ring structure–activity relationship studies
  Timothy Ivo Richardson, Jeffrey Alan Dodge, Yong Wang, Jim D. Durbin, Venkatesh Krishnan, Bryan H. Norman> ;Bioorganic & Medicinal Chemistry Letters. 2007 Oct 15
• 34 citations
  Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 4: functionalization of the benzopyran A-ring.
  Bryan H. Norman, Timothy Ivo Richardson, Jeffrey Alan Dodge, Lance Allen Pfeifer, Gregory L. Durst, Yong Wang, Jim D. Durbin, Venkatesh Krishnan, Sean R. Dinn, Shengqu...> ;Bioorganic & Medicinal Chemistry Letters. 2007 Sep 15
• 28 citations
  Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 3: Synthesis of cyclopentanone and cyclohexanone intermediates for C-ring modification.
  Timothy Ivo Richardson, Jeffrey Alan Dodge, Gregory L. Durst, Lance Allen Pfeifer, Jikesh Arvind Shah, Yong Wang, Jim D. Durbin, Venkatesh Krishnan, Bryan H. Norman> ;Bioorganic & Medicinal Chemistry Letters. 2007 Sep 1
• 22 citations
  Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 2: structure-activity relationship studies on the benzopyran scaffold.
  Timothy Ivo Richardson, Bryan H. Norman, Charles Willis Lugar, Scott Alan Jones, Yong Wang, Jim D. Durbin, Venkatesh Krishnan, Jeffrey Alan Dodge> ;Bioorganic & Medicinal Chemistry Letters. 2007 Jul 1
• 9 citations
  Structure-activity relationships of SERMs optimized for uterine antagonism and ovarian safety.
  Timothy Ivo Richardson, Scott Alan Frank, Minmin Wang, Christian Alexander Clarke, Scott Alan Jones, Bai-Ping Ying, Daniel Timothy Kohlman, Owen B. Wallace, Timothy Al...> ;Bioorganic & Medicinal Chemistry Letters. 2007 Jul 1
• Benzopyrans are selective estrogen receptor beta agonists with novel activity in models of benign prostatic hyperplasia.
  Norman, B.H., Dodge, J.A., Richardson, T.I., Borromeo, P.S., Lugar, C.W., Jones, S.A., Chen, K., Wang, Y., Durst, G.L., Barr, R.J., Montrose-Rafizadeh, C., Osborne, H....> ;J Med Chem. 2006 Oct 19
• 24 citations
  A selective estrogen receptor modulator for the treatment of hot flushes.
  Owen B. Wallace, Kenneth S Lauwers, Jeffrey Alan Dodge, Scott A. May, Joel R. Calvin, Ronald Jay Hinklin, Henry Uhlman Bryant, Pamela K. Shetler, Mary D. Adrian, Andre...> ;Journal of Medicinal Chemistry. 2006 Jan 12
• 2 citations
  Structure activity studies of the serine-AIB dipeptide domain in 2,3-dihydroisothiazole based growth hormone secretagogues.
  Britta Evers, Gerd Ruehter, Martina Berg, Jeffrey Alan Dodge, Dirk Hankotius, Ulrike Hary, Louis Nickolaus Jungheim, Hans-Juergen Mest, Eva-Maria Martin de la Nava, Mi...> ;Bioorganic & Medicinal Chemistry. 2005 Dec 15
• 38 citations
  A New Selective Estrogen Receptor Modulator with Potent Uterine Antagonist Activity, Agonist Activity in Bone, and Minimal Ovarian Stimulation
  Andrew G. Geiser, Conrad Wilson Hummel, Draper Michael William, Judith W. Henck, Ilene R. Cohen, Daniel G. Rudmann, Kevin B. Donnelly, Mary D. Adrian, Timothy Alan She...> ;Endocrinology. 2005 Oct 1
• 36 citations
  A selective estrogen receptor modulator designed for the treatment of uterine leiomyoma with unique tissue specificity for uterus and ovaries in rats.
  Conrad Wilson Hummel, Andrew G. Geiser, Henry Uhlman Bryant, Ilene R. Cohen, Robert Dean Dally, Kin Chiu Fong, Scott Alan Frank, Ronald Jay Hinklin, Scott Alan Jones, ...> ;Journal of Medicinal Chemistry. 2005 Oct 1
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