JeffreyRobertHuthMDPhD

PubMed

• 28 citations
  N-aryl-benzimidazolones as novel small molecule HSP90 inhibitors.
  Milan Bruncko, Stephen K. Tahir, Xiaohong Song, Jun Chen, Hong Ding, Jeffrey R. Huth, Sha Jin, Russell A. Judge, David Madar, Chang H. Park, Cheol-Min Park, Andrew M. ...> ;Bioorganic & Medicinal Chemistry Letters. 2010 Dec 15
• 46 citations
  Discovery of a potent and selective Bcl-2 inhibitor using SAR by NMR.
  Andrew M. Petros, Jeffrey R. Huth, Thorsten Oost, Cheol-Min Park, Hong Ding, Wang Xilu, Haichao Zhang, Paul Nimmer, Renaldo Mendoza, Chaohong Sun, Jamey Mack, Karl A. ...> ;Bioorganic & Medicinal Chemistry Letters. 2010 Nov 15
• 25 citations
  Non-peptide entry inhibitors of HIV-1 that target the gp41 coiled coil pocket.
  Kent D. Stewart, Jeffrey R. Huth, Teresa I. Ng, Keith F. McDaniel, Rebecca Hutchinson, Vincent S. Stoll, Renaldo Mendoza, Edmund D. Matayoshi, Robert J Carrick, Hongme...> ;Bioorganic & Medicinal Chemistry Letters. 2010 Jan 15
• 87 citations
  Molecular Determinants of Species-Specific Activation or Blockade of TRPA1 Channels
  Jun Chen, Xu-Feng Zhang, Michael E. Kort, Jeffrey R. Huth, Chaohong Sun, Laura J. Miesbauer, Steven Cassar, Torben R. Neelands, Victoria E. Scott, Robert B. Moreland, ...> ;The Journal of Neuroscience. 2008 May 7
• 17 citations
  Scaffold oriented synthesis. Part 2: Design, synthesis and biological evaluation of pyrimido-diazepines as receptor tyrosine kinase inhibitors
  Vijaya Gracias, Zhiqin Ji, Irini Akritopoulou-Zanze, Cele Abad-Zapatero, Jeffrey R. Huth, Danying Song, Philip J. Hajduk, Eric F. Johnson, Keith B. Glaser, Patrick A. ...> ;Bioorganic & Medicinal Chemistry Letters. 2008 Apr 15
• 57 citations
  Toxicological evaluation of thiol-reactive compounds identified using a la assay to detect reactive molecules by nuclear magnetic resonance.
  Jeffrey R. Huth, Danying Song, Renaldo Mendoza, Candice L. Black-Schaefer, Jamey Mack, Sarah A. Dorwin, Uri S. Ladror, Jean M. Severin, Karl A. Walter, Diane Bartley, ...> ;Chemical Research in Toxicology. 2007 Nov 15
• 85 citations
  Discovery and Design of Novel HSP90 Inhibitors Using Multiple Fragment‐based Design Strategies
  Jeffrey R. Huth, Chang Park, Andrew M. Petros, Kunzer Aaron R, Michael D. Wendt, Wang Xilu, Christopher L. Lynch, Jamey Mack, Kerry M. Swift, Russell A. Judge, Jun Che...> ;Chemical Biology & Drug Design. 2007 Jul 1
• 62 citations
  Enhancement of chemical rules for predicting compound reactivity towards protein thiol groups.
  James T. Metz, Jeffrey R. Huth, Philip J. Hajduk> ;Journal of Computer-Aided Molecular Design. 2007 Mar 6
• 6 citations
  Design and characterization of an engineered gp41 protein from human immunodeficiency virus-1 as a tool for drug discovery
  Kent D. Stewart, Kevin Steffy, Kevin S. Harris, John E. Harlan, Vincent S. Stoll, Jeffrey R. Huth, Karl A. Walter, Emily E. Gramling-Evans, Renaldo R. Mendoza, Jean M....> ;Journal of Computer-Aided Molecular Design. 2007 Feb 9
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