JeffreySHyamsMD

PubMed

• Outcomes in Adult Inflammatory Bowel Disease Clinical Trials: Assessment of Similarity Among Participants with Adolescent-Onset and Adult-Onset Disease.
  Turner, D., Griffiths, A., Lo, K., Kim, L., Volger, S., Zhang, R., Strauss, R., Conklin, L., Rosh, J., Hyams, J., Dubinsky, M., Cohen, S.> ;Journal of Crohn's & Colitis. 2024 Feb 26
• Identification of arginine-vasopressin receptor 1a (Avpr1a/AVPR1A) as a novel candidate gene for chronic visceral pain.
  Kader, L., Willits, A., Meriano, S., Christianson, J., La, J., Feng, B., Knight, B., Kosova, G., Deberry, J., Baumbauer, K., Young, E., Coates, M., Hyams, J.> ;Biorxiv. 2023 Dec 19
• Managing pediatric Crohn's disease: recent insights.
  Katherine Baldwin, Victoria Grossi, Jeffrey S Hyams> ;Expert Review of Gastroenterology & Hepatology. 2023 Oct 24
• 1 citations
  Progression of Pediatric Crohn's Disease Is Associated With Anti-Tumor Necrosis Factor Timing and Body Mass Index Z-Score Normalization.
  Duke Geem, David Hercules, Ranjit S Pelia, Suresh Venkateswaran, Anne Griffiths, Joshua D Noe, Jennifer L Dotson, Scott Snapper, Shervin Rabizadeh, Joel R Rosh, Robert...> ;Clinical Gastroenterology and Hepatology. 2024 Feb 1
• The State of Clinical Trials in Pediatric Inflammatory Bowel Disease.
  Jeffrey S Hyams, Richard K Russell> ;Gastroenterology Clinics of North America. 2023 Sep 1
• 1 citations
  Recommendations for Standardizing MRI-based Evaluation of Perianal Fistulizing Disease Activity in Pediatric Crohn's Disease Clinical Trials.
  Eileen Crowley, Christopher Ma, Leonard Guizzetti, Guangyong Zou, Peter J Lewindon, Michael S Gee, Jeffrey S Hyams, Michael J Rosen, Daniel von Allmen, Anthony de Buck...> ;Inflammatory Bowel Diseases. 2024 Mar 1
• 13 citations
  Gut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives.
  Juan Antonio Raygoza Garay, Williams Turpin, Sun-Ho Lee, Michelle I Smith, Ashleigh Goethel, Anne M Griffiths, Paul Moayyedi, Osvaldo Espin-Garcia, Maria Abreu, Guy L ...> ;Gastroenterology. 2023 Sep 1
• 2 citations
  Longitudinal DNA methylation profiling of the rectal mucosa identifies cell-specific signatures of disease status, severity and clinical outcomes in ulcerative colitis...
  Suresh Venkateswaran, Hari K Somineni, Jason D Matthews, Varun Kilaru, Jeffrey S Hyams, Lee A Denson, Richard Kellamayer, Greg Gibson, David J Cutler, Karen N Conneely...> ;Clinical Epigenetics. 2023 Mar 24
• 7 citations
  Real world population pharmacokinetic study in children and young adults with inflammatory bowel disease discovers novel blood and stool microbial predictors of vedoli...
  Ruben J Colman, Tomoyuki Mizuno, Keizo Fukushima, David B Haslam, Jeffrey S Hyams, Brendan Boyle, Joshua D Noe, Geert R D'Haens, Johan Van Limbergen, Kelly Chun, Jane ...> ;Alimentary Pharmacology & Therapeutics. 2023 Mar 1
• 7 citations
  GATA6-AS1 Regulates Intestinal Epithelial Mitochondrial Functions, and its Reduced Expression is Linked to Intestinal Inflammation and Less Favourable Disease Course i...
  Katya E Sosnovski, Tzipi Braun, Amnon Amir, Danielle Moshel, Marina BenShoshan, Kelli L VanDussen, Nina Levhar, Haya Abbas-Egbariya, Katia Beider, Rakefet Ben-Yishay, ...> ;Journal of Crohn's & Colitis. 2023 Jun 16
• 14 citations
  Outcomes, dosing, and predictors of vedolizumab treatment in children with inflammatory bowel disease (VEDOKIDS): a prospective, multicentre cohort study.
  Ohad Atia, Zivia Shavit-Brunschwig, Diane R Mould, Ronen Stein, Manar Matar, Marina Aloi, Oren Ledder, Gili Focht, Darja Urlep, Jeffrey Hyams, Efrat Broide, Batia Weis...> ;The Lancet. Gastroenterology & Hepatology. 2023 Jan 1
• 4 citations
  Development and Validation of the TUMMY-UC: A Patient-Reported Outcome for Pediatric Ulcerative Colitis.
  Liron Marcovitch, Gili Focht, Natalie Carmon, Claudia Tersigni, Oren Ledder, Raffi Lev-Tzion, Peter C Church, Jeffrey S Hyams, Robert N Baldassano, Athos Bousvaros, Da...> ;Gastroenterology. 2023 Apr 1
• 1 citations
  Durability of Immunity Is Low Against Severe Acute Respiratory Syndrome Coronavirus 2 Omicron BA.1, BA.2, and BA.3 Variants After Second and Third Vaccinations in Chil...
  Lorenza Bellusci, Fatema Tuz Zahra, Dena E Hopkins, Juan C Salazar, Jeffrey S Hyams, Surender Khurana> ;Gastroenterology. 2022 Dec 1
• 4 citations
  Development, Validation, and Evaluation of the Pediatric Inflammatory Crohn's Magnetic Resonance Enterography Index From the ImageKids Study.
  Gili Focht, Ruth Cytter-Kuint, Mary-Louise C Greer, Li-Tal Pratt, Denise A Castro, Peter C Church, Thomas D Walters, Jeffrey Hyams, Dan Navon, Javier Martin de Carpi, ...> ;Gastroenterology. 2022 Nov 1
• 7 citations
  Paediatric Inflammatory Bowel Disease: A Multi-Stakeholder Perspective to Improve Development of Drugs for Children and Adolescents.
  Nicholas M Croft, Lissy de Ridder, Anne M Griffiths, Jeffrey S Hyams, Frank M Ruemmele, Dan Turner, Katharine Cheng, Irja Lutsar, Marco Greco, Zuzanna Gołębiewska, Flo...> ;Journal of Crohn's & Colitis. 2023 Mar 18
• 3 citations
  Methotrexate for Primary Maintenance Therapy in Mild-to-Moderate Crohn Disease in Children.
  Katherine Baldwin, Alexa Goldfarb, Michael Brimacombe, Dena Hopkins, Jeffrey S Hyams> ;Journal of Pediatric Gastroenterology and Nutrition. 2022 Sep 1
• 7 citations
  Multicenter Cohort Study of Infliximab Pharmacokinetics and Therapy Response in Pediatric Acute Severe Ulcerative Colitis.
  Kaitlin G Whaley, Ye Xiong, Rebekah Karns, Jeffrey S Hyams, Subra Kugathasan, Brendan M Boyle, Thomas D Walters, Judith Kelsen, Neal LeLeiko, Jason Shapiro, Amanda Wad...> ;Clinical Gastroenterology and Hepatology. 2023 May 1
• 1 citations
  Barriers From Third-Party Payers to Biologic Use in Pediatric Inflammatory Bowel Disease.
  Chelsea A Lepus, Jeffrey S Hyams> ;JPGN Reports. 2022 Aug 1
• 1 citations
  Follicular Dendritic Cell Sarcoma in a Patient With Adolescent-Onset Crohn's Disease Exposed to Multiple Immunomodulator and Biologic Therapies.
  Kaitlyn Anderson, Kerry Moss, Brendan Campbell, Douglas Moote, Kari Kakazu, Jeffrey S Hyams> ;JPGN Reports. 2022 Aug 1
• 7 citations
  Utilization of Antitumor Necrosis Factor Biologics in Very Early Onset Inflammatory Bowel Disease: A Multicenter Retrospective Cohort Study From North America.
  Heyman, M. B., Kerur, B., Fiedler, K., Stahl, M., Hyams, J., Stephens, M., Lu, Y., Pfefferkorn, M., Alkhouri, R., Strople, J., Kelsen, J., Siebold, L., Goyal, A., Rosh...> ;Journal of Pediatric Gastroenterology and Nutrition. 2022 Jul 1
• 2 citations
  Targeted Assessment of Mucosal Immune Gene Expression Predicts Clinical Outcomes in Children with Ulcerative Colitis.
  Kathryn Clarkston, Rebekah Karns, Anil G Jegga, Mihika Sharma, Sejal Fox, Babajide A Ojo, Phillip Minar, Thomas D Walters, Anne M Griffiths, David R Mack, Brendan Boyl...> ;Journal of Crohn's & Colitis. 2022 Nov 23
• 3 citations
  Simplified Magnetic Resonance Index of Activity Is Useful for Terminal Ileal but not Colonic Disease in Pediatric Crohn Disease.
  Chelsea A Lepus, Douglas J Moote, Shanshan Bao, Maua H Mosha, Jeffrey S Hyams> ;Journal of Pediatric Gastroenterology and Nutrition. 2022 May 1
• 2 citations
  Methylation quantitative trait loci are largely consistent across disease states in Crohn's disease.
  Suresh Venkateswaran, Hari K Somineni, Varun Kilaru, Seyma Katrinli, Jarod Prince, David T Okou, Jeffrey S Hyams, Lee A Denson, Richard Kellermayer, Greg Gibson, David...> ;G3. 2022 Apr 4
• 15 citations
  Pharmacokinetics, Safety and Efficacy of Intravenous Vedolizumab in Paediatric Patients with Ulcerative Colitis or Crohn's Disease: Results from the Phase 2 HUBBLE Study.
  Jeffrey S Hyams, Dan Turner, Stanley A Cohen, Erzsébet Szakos, Kinga Kowalska-Duplaga, Frank Ruemmele, Nicholas M Croft, Bartosz Korczowski, Promise Lawrence, Siddhart...> ;Journal of Crohn's & Colitis. 2022 Aug 30
• 14 citations
  Antibodies-to-infliximab accelerate clearance while dose intensification reverses immunogenicity and recaptures clinical response in paediatric Crohn's disease.
  Ruben J Colman, Ye Xiong, Tomoyuki Mizuno, Jeffrey S Hyams, Joshua D Noe, Brendan Boyle, Geert R D'Haens, Johan van Limbergen, Kelly Chun, Jane Yang, Michael J Rosen, ...> ;Alimentary Pharmacology & Therapeutics. 2022 Mar 1
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Journal Articles

• Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte–Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn’s Disease  
  Lee A Denson, Bruce J Aronow, Barbara S Kirschner, Joshua D Noe, Melvin B Heyman, Ramnik J Xavier, Robert N Baldassano, Jeffrey S Hyams, Subra Kugathasan, Wallace V Cr..., Inflammatory Bowel Diseases
• Pediatric Inflammatory Bowel Disease Clinical Innovations Meeting of the Crohn’s & Colitis Foundation: Charting the Future of Pediatric IBD  
  Joel R Rosh, Athos Bousvaros, Laurie S Conklin, Caren A Heller, David Ziring, K T Park, Subra Kugathasan, Michael D Kappelman, Andrew B Grossman, Jeffrey S Hyams, Lee ..., Inflammatory Bowel Diseases
• Serologic Reactivity Reflects Clinical Expression of Ulcerative Colitis in Children  
  Subra Kugathasan, Robert N Baldassano, Lee A Denson, Joshua D Noe, Jeffrey S Hyams, Cary G Sauer, David J Keljo, Joel R Rosh, Melvin B Heyman, Neal S LeLeiko, Marian D..., Inflammatory Bowel Diseases
• Free and Bioavailable 25-Hydroxyvitamin D Concentrations Are Associated with Disease Activity in Pediatric Patients with Newly Diagnosed Treatment Naïve Ulcerative Col...  
  James Markowitz, Joel Rosh, Robert N Baldassano, Brendan Boyle, Jeffrey S Hyams, Vin Tangpricha, Subra Kugathasan, Lee A Denson, Neal S Leleiko, Cary G Sauer, Thomas R..., Inflammatory Bowel Diseases
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