JeffreyRPetrellaMD

Radiology • Durham, NC

Neuroradiology

Professor, Radiology, Duke University School of Medicine

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Office
2301 Erwin Rd
Durham, NC 27705
Phone(919) 681-9660
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Education & Training

University of Pennsylvania Health SystemFellowship, Neuroradiology, 1992 - 1994
St Vincent's Hospital and Medical CenterResidency, Radiology, 1988 - 1992
St Vincent's Hospital and Medical CenterInternship, Transitional Year, 1987 - 1988
Rutgers Robert Wood Johnson Medical SchoolClass of 1987

Certifications & Licensure

NC State Medical License 1997 - 2021
PA State Medical License 1992 - 2006
NJ State Medical License 1992 - 2005
NY State Medical License 1988 - 2015
American Board of Radiology Diagnostic Radiology
American Board of Radiology Neuroradiology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Publications & Presentations

PubMed

3 citations
Magnetic resonance imaging volumetric analysis in patients with Alternating hemiplegia of childhood: A pilot study.
Ryan Ghusayni, Jordan Richardson, Julie Uchitel, Elie Abdelnour, Melissa McLean, Lyndsey Prange, Tavis Abrahamsen, Allen W. Song, Jeffrey R. Petrella, Mohamad A. Mikati> ;European Journal of Paediatric Neurology. 2020 Feb 13
6 citations
Computational Causal Modeling of the Dynamic Biomarker Cascade in Alzheimer's Disease.
Jeffrey R. Petrella, Wenrui Hao, Adithi Rao, P. Murali Doraiswamy> ;Computational and Mathematical Methods in Medicine. 2019 Feb 3
Clinical and radiological characteristics of early versus late mild cognitive impairment in patients with comorbid depressive disorder.
Jeffrey N. Motter, Gregory H. Pelton, Kristina D'Antonio, Sara N. Rushia, Monique A. Pimontel, Jeffrey R. Petrella, Ernst Garcon, Michaela W. Ciovacco, Joel R. Sneed, ...> ;International Journal of Geriatric Psychiatry. 2018 Dec 1
6 citations
Donepezil Treatment in Patients With Depression and Cognitive Impairment on Stable Antidepressant Treatment: A Randomized Controlled Trial.
Davangere P. Devanand, Gregory H. Pelton, Kristina D'Antonio, Adam Ciarleglio, Jennifer Scodes, Howard Andrews, Julia Lunsford, John L. Beyer, Jeffrey R. Petrella, Joe...> ;American Journal of Geriatric Psychiatry. 2018 Oct 1
8 citations
Microstructural alterations of cortical and deep gray matter over a season of high school football revealed by diffusion kurtosis imaging.
Nan-Jie Gong, Samuel Kuzminski, Michael Clark, Melissa A. Fraser, Mark Sundman, Kevin M. Guskiewicz, Jeffrey R. Petrella, Chunlei Liu> ;Neurobiology of Disease. 2018 Nov 1
22 citations
Sex Differences in Cognitive Decline in Subjects with High Likelihood of Mild Cognitive Impairment due to Alzheimer's disease.
Dongwha Sohn, Katie Shpanskaya, Joseph E. Lucas, Jeffrey R. Petrella, Andrew J. Saykin, Rudolph E. Tanzi, Nagiza F. Samatova, P. Murali Doraiswamy> ;Scientific Reports. 2018 May 10
26 citations
American Society of Functional Neuroradiology–Recommended fMRI Paradigm Algorithms for Presurgical Language Assessment
David F. Black, Behroze Vachha, A. Mian, Scott H. Faro, Mohit Maheshwari, Haris I. Sair, Jeffrey R. Petrella, Jay J. Pillai, K. Welker> ;American Journal of Neuroradiology. 2017 Oct 1
1 citations
Increasing Rates of Imaging in Failed Back Surgery Syndrome Patients: Implications for Spinal Cord Stimulation.
S. Harrison Farber, Jing L. Han, Frank W. Petraglia, Robert Gramer, Siyun Yang, Promila Pagadala, Beth Parente, Jichun Xie, Jeffrey R. Petrella, Shivanand P. Lad> ;Pain Physician. 2017 Sep 1
10 citations
Predictive Utility of Marketed Volumetric Software Tools in Subjects at Risk for Alzheimer Disease: Do Regions Outside the Hippocampus Matter?
T.P. Tanpitukpongse, Maciej A. Mazurowski, J. Ikhena, Jeffrey R. Petrella> ;American Journal of Neuroradiology. 2017 Jan 5
20 citations
The Alzheimer Structural Connectome: Changes in Cortical Network Topology with Increased Amyloid Plaque Burden.
Jeffrey W Prescott, Arnaud Guidon, P Murali Doraiswamy, Kingshuk Roy Choudhury, Chunlei Liu, Jeffrey R Petrella> ;Radiology. 2016 Apr 1
6 citations
ACR-ASNR Practice Parameter for Brain PET/CT Imaging Dementia.
Kirk A. Frey, Martin A. Lodge, Carolyn C. Meltzer, Patrick J. Peller, Terence Z. Wong, Christopher P. Hess, Jeffrey R. Petrella, Haris I. Sair, Rathan M. Subramaniam> ;Clinical Nuclear Medicine. 2016 Feb 1
106 citations
Marked gender differences in progression of mild cognitive impairment over 8 years
Katherine Amy Lin, Kingshuk Roy Choudhury, Bharath G. Rathakrishnan, David M. Marks, Jeffrey R. Petrella, P. Murali Doraiswamy> ;Alzheimer's & Dementia: Translational Research & Clinical Interventions. 2015 Sep 1
16 citations
Educational attainment and hippocampal atrophy in the Alzheimer's disease neuroimaging initiative cohort
Katie Shpanskaya, Kingshuk Roy Choudhury, Christopher A. Hostage, Kelly R. Murphy, Jeffrey R. Petrella, P. Murali Doraiswamy> ;Journal of Neuroradiology. 2014 Dec 1
20 citations
The Alzheimer structural connectome: changes in cortical network topology with increased amyloid plaque burden.
Jeffrey W Prescott, Arnaud Guidon, P Murali Doraiswamy, Kingshuk Roy Choudhury, Chunlei Liu, Jeffrey R Petrella> ;Radiology. 2014 Oct 1
14 citations
Impact of 18F-florbetapir PET imaging of β-amyloid neuritic plaque density on clinical decision-making
Anthony S. Zannas, P. Murali Doraiswamy, Katie Shpanskaya, Kelly R. Murphy, Jeffrey R. Petrella, James R. Burke, Terence Z. Wong> ;Neurocase. 2014 Apr 4
11 citations
Mapping the effect of the apolipoprotein E genotype on 4-year atrophy rates in an Alzheimer disease-related brain network.
Christopher A. Hostage, Kingshuk Roy Choudhury, P. Murali Doraiswamy, Jeffrey R. Petrella> ;Radiology. 2014 Apr 1
11 citations
Donepezil treatment of older adults with cognitive impairment and depression (DOTCODE study): Clinical rationale and design
Gregory H. Pelton, Howard Andrews, Steven P. Roose, Sue M. Marcus, Kristina D'Antonio, Hala Husn, Jeffrey R. Petrella, Anthony S. Zannas, P. Murali Doraiswamy, Devange...> ;Contemporary Clinical Trials. 2014 Mar 1
8 citations
Science to practice: translating automated brain MRI volumetry in Alzheimer's disease from research to routine diagnostic use in the work-up of dementia.
Bharath G. Rathakrishnan, P. Murali Doraiswamy, Jeffrey R. Petrella> ;Frontiers in Neurology. 2014 Jan 9
4 citations
Brain atrophy rates in first degree relatives at risk for Alzheimer's
Erika J. Lampert, Kingshuk Roy Choudhury, Christopher A. Hostage, Bharath G. Rathakrishnan, Michael W. Weiner, Jeffrey R. Petrella, P. Murali Doraiswamy> ;NeuroImage: Clinical. 2014 Jan 1
21 citations
Neuroimaging and the Search for a Cure for Alzheimer Disease
Jeffrey R. Petrella> ;Radiology. 2013 Dec 1
26 citations
Mapping the effects of ApoE4, Age and Cognitive status on 18F-Florbetapir PET Measured Regional Cortical Patterns of Beta-amyloid Density and Growth
Kelly R. Murphy, Susan M. Landau, Kingshuk Roy Choudhury, Christopher A. Hostage, Katie Shpanskaya, Haris I. Sair, Jeffrey R. Petrella, Terence Z. Wong, P. Murali Dora...> ;NeuroImage. 2013 Sep 1
30 citations
Phenotypic regional functional imaging patterns during memory encoding in mild cognitive impairment and Alzheimer's disease.
Jeffrey N. Browndyke, Kelly S. Giovanello, Jeffrey R. Petrella, Kathleen M. Hayden, Ornit Chiba-Falek, Karen A. Tucker, James R. Burke, Kathleen A. Welsh-Bohmer> ;Alzheimers & Dementia. 2013 May 1
10 citations
Prevalence of Alzheimer's Pathologic Endophenotypes in Asymptomatic and Mildly Impaired First-Degree Relatives
Erika J. Lampert, Kingshuk Roy Choudhury, Christopher A. Hostage, Jeffrey R. Petrella, P. Murali Doraiswamy> ;PLOS ONE. 2013 Apr 17
3 citations
From the bridges of Königsberg to the fields of Alzheimer Connecting the dots
Jeffrey R. Petrella, P. Murali Doraiswamy> ;Neurology. 2013 Apr 9
33 citations
Dissecting the Gene Dose-Effects of the APOE ε4 and ε2 Alleles on Hippocampal Volumes in Aging and Alzheimer’s Disease
Christopher A. Hostage, Kingshuk Roy Choudhury, P. M. Doraiswamy, Jeffrey R. Petrella> ;PLOS ONE. 2013 Feb 6
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Press Mentions

Associations of Regional Brain Structural Differences with Aging, Modifiable Risk Factors for Dementia, and Cognitive PerformanceDecember 2nd, 2019
Association of Altered Liver Enzymes with AD, Cognition, Neuroimaging Measures, and Cerebrospinal Fluid BiomarkersJuly 31st, 2019
Imaging Shows Brain Connection Breakdown in Early Alzheimer's DiseaseDecember 1st, 2014
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