JeffreyRaizerMD

Neurology • Chicago, IL

Neurooncology

Professor, Neurology, Northwestern University Medical School

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Office
675 N Saint Clair St
Chicago, IL 60611
Phone+1 312-695-0990

Fax+1 312-695-1435
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Education & Training

Memorial Sloan Kettering Cancer CenterFellowship, Neuro-Oncology, 1996 - 1998
Yale-New Haven Medical CenterResidency, Neurology, 1993 - 1996
NYU Grossman School of MedicineResidency, Internal Medicine, 1991 - 1993
New York Medical CollegeClass of 1991

Certifications & Licensure

IL State Medical License 2003 - 2026
NY State Medical License 1996 - 2021
CT State Medical License 1993 - 1996
American Board of Psychiatry and Neurology Neurology
UCNSNeuro-Oncology

Awards, Honors, & Recognition

Meaningful Use Stage 1 Certification Centers for Medicare & Medicaid Services, 2011
Super Doctor SuperDoctors.com

Clinical Trials

Combination Chemotherapy Following Radiation Therapy in Treating Patients With Malignant Glioma Start of enrollment: 1999 Dec 01
Completed
Phase 1
Taurolidine in Treating Patients With Recurrent or Progressive Glioma Start of enrollment: 2001 May 01
Completed
Phase 1
Arsenic Trioxide, Temozolomide, and Radiation Therapy in Treating Patients With Malignant Glioma That Has Been Removed By Surgery Start of enrollment: 2005 May 01
Active, not recruiting
Phase 1, Phase 2
Pemetrexed Disodium in Treating Patients With Recurrent Malignant Gliomas, Primary CNS Lymphoma, or Brain Metastases Start of enrollment: 2005 Nov 01
Active, not recruiting
Phase 2
Bevacizumab in Treating Patients With Recurrent or Progressive Glioma Start of enrollment: 2006 Mar 01
Completed
Phase 2
Vatalanib in Treating Patients With Recurrent or Progressive Meningioma Start of enrollment: 2006 May 01
Completed
Phase 2
131-I-TM-601 Study in Adults With Solid Tumors Start of enrollment: 2006 Aug 01
Completed
Phase 1
AQ4N in Combination With Radiotherapy and Temozolomide in Subjects With Newly Diagnosed Glioblastoma Multiforme Start of enrollment: 2006 Oct 01
Unknown status
Phase 1, Phase 2
Levetiracetam in Treating Patients With Seizures Caused by Brain Metastases Start of enrollment: 2007 Feb 01
Withdrawn
Not Applicable
Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal Metastases Start of enrollment: 2007 Jan 01
Completed
Early Phase 1
VNP40101M and Temozolomide in Treating Patients With Progressive or Relapsed Malignant Glioma Start of enrollment: 2007 Aug 01
Terminated
Phase 1
A Study of 131I-TM601 in Adults With Recurrent Malignant Glioma Start of enrollment: 2008 Aug 01
Unknown status
Phase 1, Phase 2
Bevacizumab and Erlotinib After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma Start of enrollment: 2009 Jul 07
Completed
Phase 2
Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSL Start of enrollment: 2008 Nov 01
Withdrawn
Early Phase 1
Presurgery Bortezomib for Recurrent Malignant Gliomas Followed by Postop Bortezomib & Temozolomide Start of enrollment: 2009 May 01
Completed
Phase 2
Study of AR-67 in Adult Patients With Recurrence of Glioblastoma Multiforme (GBM) or Gliosarcoma Start of enrollment: 2009 Dec 01
Unknown status
Phase 2
Alpha-lipoic Acid in Patients at Risk for Paclitaxel Induced Neuropathy Start of enrollment: 2012 Feb 01
Completed
Phase 1, Phase 2
Intrathecal Trastuzumab for Leptomeningeal Metastases in HER2+ Breast Cancer Start of enrollment: 2011 Aug 01
Completed
Phase 1, Phase 2
Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma Start of enrollment: 2011 Sep 01
Completed
Phase 2
Efficacy of Hypofractionated XRT w/Bev. + Temozolomide for Recurrent Gliomas Start of enrollment: 2011 Dec 14
Terminated
Phase 2
Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma Start of enrollment: 2011 Nov 01
Completed
Phase 3
Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma Start of enrollment: 2012 Dec 20
Completed
Phase 2
A Phase 1b/2 Study of PLX3397 + Radiation Therapy + Temozolomide in Patients With Newly Diagnosed Glioblastoma Start of enrollment: 2013 Jul 18
Completed
Phase 1, Phase 2
Vaccine Therapy With Bevacizumab Versus Bevacizumab Alone in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery Start of enrollment: 2013 May 01
Terminated
Phase 2
Bevacizumab in Pats w/ Recurrent ST Brain Metas Who Have Failed Whole Brain Radiation Therapy Start of enrollment: 2013 Nov 27
Completed
Phase 2
Phase Ib/II Study of Buparlisib Plus Carboplatin or Lomustine in Patients With Recurrent Glioblastoma Multiforme Start of enrollment: 2014 Feb 28
Completed
Phase 1
A Phase 2 Study of BGJ398 in Patients With Recurrent GBM Start of enrollment: 2013 Dec 09
Completed
Phase 2
Safety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma Multiforme Start of enrollment: 2014 May 01
Completed
Phase 1, Phase 2
Tremelimumab and Durvalumab in Combination or Alone in Treating Patients With Recurrent Malignant Glioma Start of enrollment: 2016 Nov 01
Completed
Phase 2
Safety and Tolerability Study of AutoSynVax™ Vaccine in Subjects With Advanced Cancer Start of enrollment: 2017 Jan 01
Terminated
Phase 1
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Publications & Presentations

PubMed

A qualitative evaluation of factors influencing Tumor Treating fields (TTFields) therapy decision making among brain tumor patients and physicians.
Madison Lyleroehr, Leilani Lacson, Timothy Kruser, Alexander Hou, Sean Sachdev, Margaret Schwartz, Jessica Bajas Pa, Ray Lezon, Karyn Schmidt, Christina Amidei, Karen ...> ;BMC Cancer. 2024 Apr 25
3 citations
ILUSTRO: Phase II Multicohort Trial of Zolbetuximab in Patients with Advanced or Metastatic Claudin 18.2-Positive Gastric or Gastroesophageal Junction Adenocarcinoma.
Samuel J Klempner, Keun-Wook Lee, Kohei Shitara, Jean-Phillippe Metges, Sara Lonardi, David H Ilson, Nicola Fazio, Tae Yong Kim, Li-Yuan Bai, Diarmuid Moran, Jianning ...> ;Clinical Cancer Research. 2023 Oct 2
1 citations
Pudexacianinium (ASP5354) chloride for ureter visualization in participants undergoing laparoscopic, minimally invasive colorectal surgery.
Matthew Albert, Leticia Delgado-Herrera, Jennifer Paruch, Pauline Gerritsen-van Schieveen, Tomoyoshi Kishimoto, Shin Takusagawa, Na Cai, John Fengler, Jeffrey Raizer> ;Surgical Endoscopy. 2023 Sep 1
38 citations
NRG Oncology/RTOG1205: A Randomized Phase II Trial of Concurrent Bevacizumab and Reirradiation Versus Bevacizumab Alone as Treatment for Recurrent Glioblastoma.
Christina I Tsien, Stephanie L Pugh, Adam P Dicker, Jeffrey J Raizer, Martha M Matuszak, Enrico C Lallana, Jiayi Huang, Ozer Algan, Nimisha Deb, Lorraine Portelance, J...> ;Journal of Clinical Oncology. 2023 Feb 20
4 citations
Phase 1 trial of zolbetuximab in Japanese patients with CLDN18.2+ gastric or gastroesophageal junction adenocarcinoma.
Kohei Shitara, Akihito Kawazoe, Akihiro Hirakawa, Yuka Nakanishi, Satomi Furuki, Musashi Fukuda, Yoko Ueno, Jeffrey Raizer, Ahsan Arozullah> ;Cancer Science. 2023 Apr 1
8 citations
A multi-institutional phase II trial of bevacizumab for recurrent and refractory meningioma.
Priya Kumthekar, Sean Aaron Grimm, Marc C Chamberlain, David Schiff, Patrick Y Wen, Fabio Massaiti Iwamoto, Demirkan Besim Gursel, David A Reardon, Benjamin Purow, Mas...> ;Neuro-Oncology Advances. 2022 Aug 19
22 citations
A phase I/II study of intrathecal trastuzumab in human epidermal growth factor receptor 2-positive (HER2-positive) cancer with leptomeningeal metastases: Safety, effic...
Priya U Kumthekar, Michael J Avram, Andrew B Lassman, Nancy U Lin, Eudocia Lee, Sean A Grimm, Margaret Schwartz, Kirsten L Bell Burdett, Rimas V Lukas, Karan Dixit, Is...> ;Neuro-Oncology. 2023 Mar 14
25 citations
Infigratinib in Patients with Recurrent Gliomas and FGFR Alterations: A Multicenter Phase II Study.
Moran, S. E., Andrew B Lassman, Juan Manuel Sepúlveda-Sánchez, Timothy F Cloughesy, Miguel J Gil-Gil, Vinay K Puduvalli, Jeffrey J Raizer, Filip Y F De Vos, Patrick Y ...> ;Clinical Cancer Research. 2022 Jun 1
5 citations
A multi-center prospective study of re-irradiation with bevacizumab and temozolomide in patients with bevacizumab refractory recurrent high-grade gliomas.
Karan Dixit, Sean Sachdev, Christina Amidei, Priya Kumthekar, Tim J. Kruser, Vinai Gondi, Sean Grimm, Rimas V. Lukas, Martin K. Nicholas, Steven J. Chmura, Angela J. F...> ;Journal of Neuro-Oncology. 2021 Oct 24
22 citations
A Bayesian Adaptive Randomized Phase II Multicenter Trial of Bevacizumab with or without Vorinostat in Adults with Recurrent Glioblastoma.
Vinay K. Puduvalli, Jing Wu, Ying Yuan, Terri S. Armstrong, Elizabeth Vera, Jimin Wu, Jihong Xu, Pierre Giglio, Howard Colman, Tobias Walbert, Jeffrey Raizer, Morris D...> ;Neuro-Oncology. 2020 Oct 14
42 citations
CODEL: phase III study of RT, RT + TMZ, or TMZ for newly diagnosed 1p/19q codeleted oligodendroglioma. Analysis from the initial study design.
Kurt A. Jaeckle, Karla V. Ballman, Martin J. van den Bent, Caterina Giannini, Evanthia Galanis, Paul D. Brown, Robert B. Jenkins, J. Gregory Cairncross, Wolfgang Wick,...> ;Neuro-Oncology. 2021 Mar 25
48 citations
Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma.
Erik Ladomersky, Lijie Zhai, Kristen L. Lauing, April Bell, Jiahui Xu, Masha Kocherginsky, Bin Zhang, Jennifer D. Wu, Joseph R. Podojil, Leonidas C. Platanias, Aaron M...> ;Clinical Cancer Research. 2020 Oct 1
18 citations
NRG/RTOG 1122: A phase 2, double-blinded, placebo-controlled study of bevacizumab with and without trebananib in patients with recurrent glioblastoma or gliosarcoma
Eudocia Q. Lee, Peixin Zhang, Patrick Y. Wen, Elizabeth R. Gerstner, David A. Reardon, Kenneth Aldape, John DeGroot, Edward Pan, Jeffrey Raizer, Lyndon Kim, Steven J. ...> ;Cancer. 2020 Jun 15
42 citations
Cerebrospinal fluid circulating tumor cells as a quantifiable measurement of leptomeningeal metastases in patients with HER2 positive cancer.
Rachna Malani, Martin Fleisher, Priya Kumthekar, Xuling Lin, Antonio Omuro, Morris D. Groves, Nan Lin, Michelle E. Melisko, Andrew B. Lassman, Suriya Jeyapalan, Andrew...> ;Journal of Neuro-Oncology. 2020 Jun 6
2 citations
The Impact of Perioperative Arterial Infarct on Recurrence, Functional Outcomes, and Survival in Glioblastoma Patients.
Jakob T. Lupa, Jeffrey Raizer, Irene Helenowski, Benjamin P. Liu, Kartik Kesavabhotla, Matthew C. Tate> ;Frontiers in Oncology. 2020 May 13
18 citations
Buparlisib plus carboplatin or lomustine in patients with recurrent glioblastoma: a phase Ib/II, open-label, multicentre, randomised study.
Mark Rosenthal, Paul Clement, Mario Campone, Miguel Gil-Gil, John DeGroot, Olivier Chinot, Ahmed Idbaih, Hui K Gan, Jeffrey Raizer, Patrick Y. Wen, Estela Pineda, Vale...> ;ESMO Open. 2020 Jan 1
44 citations
Extensive brainstem infiltration, not mass effect, is a common feature of end-stage cerebral glioblastomas.
Michael Drumm, Karan Dixit, Sean Grimm, Priya Kumthekar, Rimas V. Lukas, Jeffrey Raizer, Roger Stupp, Milan G. Chheda, Kwok Ling Kam, Matthew McCord, Sean Sachdev, Tim...> ;Neuro-Oncology. 2019 Nov 11
21 citations
Author Correction: Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma
Junfei Zhao, Andrew X. Chen, Robyn D. Gartrell, Andrew M. Silverman, Luis Aparicio, Tim Chu, Darius Bordbar, David Shan, Jorge Samanamud, Aayushi Mahajan, Ioan Filip, ...> ;Nature Medicine. 2019 Jun 1
92 citations
Liquid biopsy in central nervous system metastases: a RANO review and proposals for clinical applications.
Adrienne Boire, Dieta Brandsma, Priscilla K. Brastianos, Emilie Le Rhun, Manmeet Ahluwalia, Larry Junck, Michael Glantz, Morris D. Groves, Eudocia Q. Lee, Nan Lin, Jef...> ;Neuro-Oncology. 2019 May 6
19 citations
Anticonvulsant Prophylaxis and Steroid Use in Adults With Metastatic Brain Tumors: ASCO and SNO Endorsement of the Congress of Neurological Surgeons Guidelines.
Susan M. Chang, Hans Messersmith, Manmeet Ahluwalia, David W. Andrews, Priscilla K. Brastianos, Laurie E. Gaspar, Na Tosha Gatson, Justin T. Jordan, Mustafa Khasraw, A...> ;Journal of Clinical Oncology. 2019 Mar 18
17 citations
Anticonvulsant prophylaxis and steroid use in adults with metastatic brain tumors: summary of SNO and ASCO endorsement of the Congress of Neurological Surgeons guideli...
Susan M. Chang, Hans Messersmith, Manmeet Ahluwalia, David W. Andrews, Priscilla K. Brastianos, Laurie E. Gaspar, Na Tosha Gatson, Justin T. Jordan, Mustafa Khasraw, A...> ;Neuro-Oncology. 2019 Mar 18
504 citations
Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma.
Junfei Zhao, Andrew X. Chen, Robyn D. Gartrell, Andrew M. Silverman, Luis Aparicio, Tim Chu, Darius Bordbar, David Shan, Jorge Samanamud, Aayushi Mahajan, Ioan Filip, ...> ;Nature Medicine. 2019 Feb 11
103 citations
Proposed response assessment and endpoints for meningioma clinical trials: Report from the Response Assessment in Neuro-Oncology Working Group
Raymond Y. Huang, Wenya Linda Bi, Michael Weller, Thomas Kaley, Jaishri O. Blakeley, Ian F. Dunn, Evanthia Galanis, Matthias Preusser, Michael W. McDermott, Leland Rog...> ;Neuro-Oncology. 2019 Jan 1
16 citations
Response assessment of meningioma: 1D, 2D, and volumetric criteria for treatment response and tumor progression.
Raymond Y. Huang, Prashin Unadkat, Wenya Linda Bi, Elizabeth George, Matthias Preusser, Jay D McCracken, Joseph R. Keen, William L. Read, Jeffrey J. Olson, Katharina S...> ;Neuro-Oncology. 2018 Aug 2
2 citations
Widespread disseminated osseous metastases of intracranial meningioma with over 27-year-survivorship: a unique, idiosyncratic case.
Betty Mishkin, Jeffrey Raizer, Jonathan B. Bell> ;Journal of Neuro-Oncology. 2018 Jun 15
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