Jeffrey Lawrence Saver MD

Hospital/Neurohospitalist, Vascular Neurology

SA Vice-Chair and Professor, Neurology, UCLA School of Medicine Director of the UCLA Comprehensive Stroke and Vascular Neurology Program

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710 Westwood Plaza, 1-240 RNRCLos Angeles, CA 90095
Phone+1 310-794-6379
Fax+1 310-794-6379

Summary

Dr. Jeffrey Saver is a neurologist in Los Angeles, CA and is affiliated with multiple hospitals in the area, including Ronald Reagan UCLA Medical Center and UCLA Medical Center-Santa Monica. He received his medical degree from Harvard Medical School and has been in practice 31 years. He specializes in stroke and vascular neurology and in behavioral and cognitive neurology. He has more than 775 publications and over 102,000 citings.

Education & Training

Rhode Island Hospital/Brown University HealthFellowship, Vascular Neurology, 1991 - 1992
Brown UniversityFellowship, Cerebrovascular disease, 1991 - 1992
University of Iowa Hospitals and ClinicsResidency, Neurology, 1990 - 1991
University of Iowa Hospitals and ClinicsFellowship, Cognitive Neuroscience, 1990 - 1991
Beth Israel Deaconess Medical Center/Harvard Medical SchoolResidency, Neurology, 1987 - 1990
Mass General Brigham/Brigham and Women's HospitalInternship, Internal Medicine, 1986 - 1987
Harvard Medical SchoolClass of 1986

Certifications & Licensure

CA State Medical License 1994 - 2026
IL State Medical License 1992 - 1996
IA State Medical License 1990 - 1993
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2010-2014
Top Doctors:LA Area Castle Connolly, 2013
Top Doctors:Southern California Castle Connolly, 2012

Clinical Trials

Field Administration of Stroke Therapy - Magnesium (FAST-MAG) Trial Start of enrollment: 2005 Jan 01
Completed
Phase 3
A Randomized Trial of Unruptured Brain AVMs Start of enrollment: 2006 Oct 01
Completed
Phase 3
Patent Foramen Ovale Closure or Medical Therapy After Stroke - RESPECT Trial Start of enrollment: 2003 Aug 01
Completed
Not Applicable
A Safety and Dose Finding Study of Plasmin (Human) Administered Into the Middle Cerebral Artery of Stroke Patients Start of enrollment: 2009 Nov 01
Completed
Phase 1, Phase 2
SOLITAIRE™ FR With the Intention For Thrombectomy (SWIFT) Study Start of enrollment: 2010 Jan 01
Completed
Not Applicable
Efficacy and Safety Study of GM602 in Patients With Acute Middle Cerebral Artery Ischemic Stroke Within 18 Hours Start of enrollment: 2011 Mar 08
Completed
Phase 2
Endovascular Magnesium Sampling in Acute Stroke Start of enrollment: 2012 Mar 01
Terminated
Not Applicable
Intra-arterial Magnesium Administration for Acute Stroke Start of enrollment: 2012 Mar 01
Terminated
Phase 1, Phase 2
Solitaire™ With the Intention For Thrombectomy as PRIMary Endovascular Treatment (SWIFT PRIME) Trial Start of enrollment: 2012 Dec 01
Completed
Not Applicable
Field Administration of Stroke Therapy-Blood Pressure Lowering Start of enrollment: 2013 Apr 01
Terminated
Phase 2
Surgical Indirect Revascularization For Symptomatic Intracranial Arterial Stenosis Start of enrollment: 2013 Mar 01
Completed
Not Applicable
Transcranial Direct Current Stimulation as a Neuroprotection in Acute Stroke Start of enrollment: 2018 Sep 28
Completed
Not Applicable
Efficacy and Safety of Trans Sodium Crocetinate (TSC) for Treatment of Suspected Stroke Start of enrollment: 2019 Aug 22
Terminated
Phase 2
Transcranial Direct Current Stimulation as a Neuroprotection in Acute Stroke Before and After Thrombectomy Start of enrollment: 2019 Jul 28
Terminated
Not Applicable
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Publications & Presentations

PubMed

Association Between Collateral Status, Blood Pressure During Thrombectomy, and Clinical Outcomes in Patients With Basilar Artery Occlusion.
Cong Luo, Thanh N Nguyen, Rui Li, Chunrong Tao, Xiaozhong Jing
Neurology. 2025-05-13
Is there diurnal variation in neuroprotective and thrombolytic therapy effect upon acute cerebral ischemia outcome?
Fatima Pariona-Vargas, Katherine T Mun, Eng H Lo, Sidney Starkman, Nerses Sanossian
Journal of Stroke and Cerebrovascular Diseases. 2025-05-01
Endovascular thrombectomy in acute stroke with a large ischemic core: A systematic review and meta-analysis of randomized controlled trials.
Chun-Hsien Lin, Meng Lee, Bruce Ovbiagele, David S Liebeskind, Borja Sanz-Cuesta
Plos Medicine. 2025-04-17

Journal Articles

Stroke Thrombolysis with Tenecteplase to Reduce Emergency Department Spread of Coronavirus Disease 2019 and Shortages of Alteplase
Steven J Warach, Jeffrey L Saver, JAMA Neurology
Association Between Thrombolytic Door-to-Needle Time and 1-Year Mortality and Readmission in Patients with Acute Ischemic Stroke
Shumei Man, Jeffrey L Saver, Eric E Smith, Deepak L Bhatt, Lee H Schwamm, Gregg C Fonarow, JAMA
Striving for Ideal Cardiovascular and Brain Health
Mary Cushman, Jeffrey L Saver, JAMA
Effect of Alteplase vs Aspirin on Functional Outcome for Patients with Acute Ischemic Stroke and Minor Nondisabling Neurologic DeficitsThe PRISMS Randomized Clinical T...
Pooja Khatri, Jeffrey L Saver, Anjan Chatterjee, Joseph Broderick, Edward C Jauch, Steven R Levine, Achala Vagal, Dawn O Kleindorfer, Matthew Starr, JAMA
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Lectures

Transcranial Doppler Course
David Geffen School of Medicine at UCLA, Los Angeles, California - 7/24/2013
Transcranial Doppler Course
UCLA Health System, Los Angeles, California - 2/13/2013
Transcranial Doppler Course
UCLA Health System, Los Angeles, California - 11/14/2012
Tempus Cerebrum Est: Treating Acute Stroke in the First Minutes After Onset
Los Angeles, CA - 2/14/2014
Ultra-early Magnesium Treatment in Suspected Lacunar Stroke(FAST-MAG)
Los Angeles, CA - 2/13/2014
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Authored Content

Stroke Thrombolysis with Tenecteplase to Reduce Emergency Department Spread of Coronavirus Disease 2019 and Shortages of AlteplaseJuly 2020
Association Between Thrombolytic Door-to-Needle Time and 1-Year Mortality and Readmission in Patients with Acute Ischemic StrokeJune 2020
Thrombectomy 6 to 24 Hours After Stroke with a Mismatch Between Deficit and InfarctNovember 2017
Thrombectomy 6 to 24 Hours After Stroke with a Mismatch Between Deficit and InfarctNovember 2017
Thrombectomy 6 to 24 Hours After Stroke with a Mismatch Between Deficit and InfarctNovember 2017
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Press Mentions

Patent Foramen Ovale: Heart ‘Tunnel’ Linked to Stroke, MigrainesJanuary 6th, 2025
Preventing Fever in Patients with Acute Vascular Brain InjurySeptember 25th, 2024
Medicare Analysis Suggests Benefit of PFO Closure Beyond Age 60May 17th, 2024
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Grant Support

Los Angeles - Southern California (LASC) NIH StrokeNet Regional Coordinating CenterUNIVERSITY OF CALIFORNIA LOS ANGELES2018–2028
Los Angeles - Southern California (LASC) NIH StrokeNet Regional Coordinating CenterUNIVERSITY OF CALIFORNIA LOS ANGELES2018–2028
Los Angeles - Southern California (LASC) NIH StrokeNet Regional Coordinating CenterUNIVERSITY OF CALIFORNIA LOS ANGELES2018–2028
Los Angeles - Southern California (LASC) NIH StrokeNet Regional Coordinating CenterUNIVERSITY OF CALIFORNIA LOS ANGELES2018–2028
Southwest Strategies to Innovate Emergency Care Clinical Trials Network (SW SIREN)UNIVERSITY OF CALIFORNIA LOS ANGELES2017–2028
Southwest Strategies to Innovate Emergency Care Clinical Trials Network (SW SIREN)UNIVERSITY OF CALIFORNIA LOS ANGELES2017–2028
StrokeNet Thrombectomy Endovascular Platform (STEP)MEDICAL UNIVERSITY OF SOUTH CAROLINA2022–2024
Field Administration Of Stroke Therapy-Magnesium Trial (Fast-Mag)National Institute Of Neurological Disorders And Stroke2008–2012
UCLA Spotrias Center Application Renewal-Program ProjectNational Institute Of Neurological Disorders And Stroke2008–2011
Telestroke In The FieldNational Institute Of Neurological Disorders And Stroke2008–2011
Field Administration Of Stroke Therapy-Magnesium Trial (Fast-MagNational Institute Of Neurological Disorders And Stroke2008–2011
Carrer DevelopmentNational Institute Of Neurological Disorders And Stroke2008–2011
Administrative CoreNational Institute Of Neurological Disorders And Stroke2008–2011
UCLA Spotrias CenterNational Institute Of Neurological Disorders And Stroke2009
UCLA Spotrias Center ApplicationNational Institute Of Neurological Disorders And Stroke2003–2007
Prehospital Stroke StudiesNational Institute Of Neurological Disorders And Stroke2003–2007
Field Administration Of Stroke Therapy - Magnesium TrialNational Institute Of Neurological Disorders And Stroke2003–2007
Core--Career DevelopmentNational Institute Of Neurological Disorders And Stroke2003–2007
Paramedic Field Initiation Of Magnesium NeuroprotectiveNational Institute Of Neurological Disorders And Stroke1999–2003
Vitamin Intervention For Stroke Prevention (VISP)National Center For Research Resources1999–2001
Vitamine Intervention For Stroke Prevention (VISP)National Center For Research Resources1998
Randomized Trial Of ORG 10172 In Actue Or Progressing Ischemic StrokeNational Center For Research Resources1996–1997