JenniferJocelynClarkMD

Pediatric Hematology & Oncology • Denver, CO

Physician

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Office
2055 High Street
#340
Denver, CO 80205
Phone+1 303-832-2344

Fax+1 303-832-3721
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Education & Training

Children's Hospital/Boston Medical CenterFellowship, Pediatric Hematology/Oncology, 2000 - 2003
Brigham and Women's Hospital/Children's Hospital/Harvard Medical SchoolResidency, Internal Medicine/Pediatrics, 1996 - 2000
Massachusetts General HospitalInternship, Internal Medicine, 1996 - 1997
Johns Hopkins University School of MedicineClass of 1996

Certifications & Licensure

CO State Medical License 2007 - 2025
MA State Medical License 1998 - 2009
American Board of Internal Medicine Internal Medicine
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Clinical Trials

Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma Start of enrollment: 2001 Oct 18
Active, not recruiting
Phase 3
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies Start of enrollment: 2008 Jul 17
Recruiting
Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer Start of enrollment: 2003 Oct 13
Completed
Study of Kidney Tumors in Younger Patients Start of enrollment: 2006 Feb 27
Recruiting
Collecting and Storing Biological Samples From Patients With Ewing Sarcoma Start of enrollment: 2008 Feb 04
Completed
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma Start of enrollment: 2000 Nov 06
Recruiting
Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma Start of enrollment: 1999 Mar 15
Completed
Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors Start of enrollment: 2004 Feb 16
Completed
Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor Start of enrollment: 2009 Jul 13
Active, not recruiting
Phase 3
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 14
Active, not recruiting
Phase 3
Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Start of enrollment: 2010 Aug 09
Completed
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma Start of enrollment: 2010 Aug 09
Active, not recruiting
Phase 3
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Start of enrollment: 2010 Nov 22
Active, not recruiting
Phase 3
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia Start of enrollment: 2011 Apr 04
Completed
Phase 3
Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Start of enrollment: 2011 Jun 20
Active, not recruiting
Phase 3
A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum Start of enrollment: 2012 Feb 01
Intergroup Trial for Children or Adolescents With B-Cell NHL or B-AL: Evaluation of Rituximab Efficacy and Safety in High Risk Patients Start of enrollment: 2012 Jun 01
Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma Start of enrollment: 2013 Feb 12
Completed
Phase 2
Brentuximab Vedotin or Crizotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II-IV Anaplastic Large Cell Lymphoma Start of enrollment: 2013 Nov 13
Completed
Phase 2
Eribulin Mesylate in Treating Patients With Recurrent or Refractory Osteosarcoma Start of enrollment: 2014 Aug 01
Completed
Phase 2
Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Start of enrollment: 2014 Jul 11
Active, not recruiting
Phase 2, Phase 3
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 01
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Publications & Presentations

PubMed

21 citations
Molecular biomarkers for the evaluation of colorectal cancer: Guideline summary from the American society for clinical pathology, college of American pathologists, ass...
Antonia R. Sepulveda, Stanley R. Hamilton, Carmen J. Allegra, Wayne W. Grody, Allison M. Cushman-Vokoun, William K. Funkhouser, Scott Kopetz, Christopher H. Lieu, Nora...> ;Journal of Oncology Practice. 2017 Mar 28
249 citations
Molecular biomarkers for the evaluation of colorectal cancer: Guideline from The American Society for Clinical Pathology, College of American Pathologists, Association...
Antonia R. Sepulveda, Stanley R. Hamilton, Carmen J. Allegra, Wayne W. Grody, Allison M. Cushman-Vokoun, William K. Funkhouser, Scott Kopetz, Christopher H. Lieu, Nora...> ;Journal of Clinical Oncology. 2017 Feb 6
Hematopoietic stem cell transplantation in unique pediatric populations: adolescents, infants, and children with down syndrome.
Duncan, C. N.,Clark, J. J.,Silverman, L. B.> ;Biol Blood Marrow Transplant. 2013 Jan
34 citations
Uniform sensitivity of FLT3 activation loop mutants to the tyrosine kinase inhibitor midostaurin
Elly Barry, Jennifer J. Clark, Jan Cools, Johannes Roesel, D. Gary Gilliland> ;Blood. 2007 Dec 15
Early childhood externalising behaviour problems: child, parenting, and family-related predictors over time.
Miller-Lewis, L.R., Baghurst, P.A., Sawyer, M.G., Prior, M.R., Clark, J.J., Arney, F.M., Carbone, J.A.> ;J Abnorm Child Psychol. 2006 Dec
1073 citations
MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia.
Yana Pikman, Benjamin H. Lee, Thomas Mercher, Elizabeth McDowell, Benjamin L. Ebert, Maricel Gozo, Adam Cuker, Gerlinde Wernig, Sandra A. Moore, Ilene Galinsky, Daniel...> ;Plos Medicine. 2006 Jul 18
292 citations
The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic ...
Ross L. Levine, Marc M. Loriaux, Brian J. P. Huntly, Mignon L. Loh, M. Beran, Eric P. Stoffregen, Roland Berger, Jennifer J. Clark, Stephanie G. Willis, Kim Nguyen, Ni...> ;Blood. 2005 Nov 15
204 citations
Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412
Joseph D. Growney, Jennifer J. Clark, Jennifer Adelsperger, Richard Stone, Doriano Fabbro, James D. Griffin, D. Gary Gilliland> ;Blood. 2005 Jul 15
2265 citations
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.
Ross L. Levine, Martha Wadleigh, Jan Cools, Benjamin L. Ebert, Gerlinde Wernig, Brian J. P. Huntly, Titus J. Boggon, Iwona Wlodarska, Jennifer J. Clark, Sandra A. Moor...> ;Cancer Cell. 2005 Apr 1
18 citations
EGFR inhibition in non-small cell lung cancer: resistance, once again, rears its ugly head.
Jennifer J. Clark, Jan Cools, D. Gary Gilliland> ;Plos Medicine. 2005 Feb 22
512 citations
Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412
Richard Stone, Daniel J. DeAngelo, Virginia M. Klimek, Ilene Galinsky, Eli Estey, Stephen D. Nimer, Wilson Grandin, David Lebwohl, Yanfeng Wang, Pamela S. Cohen, Edwar...> ;Blood. 2005 Jan 1
62 citations
Variable sensitivity of FLT3 activation loop mutations to the small molecule tyrosine kinase inhibitor MLN518.
Jennifer J. Clark, Jan Cools, David P. Curley, Jin-Chen Yu, Nathalie Lokker, Neill A. Giese, D. Gary Gilliland> ;Blood. 2004 Nov 1
Use of health and school-based services in Australia by young people with attention-deficit/hyperactivity disorder.
Sawyer, M.G., Rey, J.M., Arney, F.M., Whitham, J.N., Clark, J.J., Baghurst, P.A.> ;J Am Acad Child Adolesc Psychiatry. 2004 Nov
23 citations
Hemoglobin Jamaica plain--a sickling hemoglobin with reduced oxygen affinity.
Alon Geva, Jennifer J. Clark, Yuxun Zhang, Anthony Popowicz, James M. Manning, Ellis J. Neufeld> ;The New England Journal of Medicine. 2004 Oct 7
141 citations
Prediction of resistance to small molecule FLT3 inhibitors: implications for molecularly targeted therapy of acute leukemia.
Jan Cools, Nicole Mentens, Pascal Furet, Doriano Fabbro, Jennifer J. Clark, James D. Griffin, Peter Marynen, D. Gary Gilliland> ;Cancer Research. 2004 Sep 15
Recuse yourself--you're biased!
Blair Holladay, E., Gill, G., Clark, J.J.> ;Diagn Cytopathol. 2003 Nov
1229 citations
A Tyrosine Kinase Created by Fusion of the PDGFRA and FIP1L1 Genes as a Therapeutic Target of Imatinib in Idiopathic Hypereosinophilic Syndrome
Jan Cools, Daniel J. DeAngelo, Jason Gotlib, Elizabeth H. Stover, Robert D. Legare, J. E. Cortes, Jeffrey L. Kutok, Jennifer J. Clark, Ilene Galinsky, James D. Griffin...> ;The New England Journal of Medicine. 2003 Mar 27
9 citations
Update in childhood acute myeloid leukemia: recent developments in the molecular basis of disease and novel therapies.
Jennifer J. Clark, Franklin O. Smith, Robert J. Arceci> ;Current Opinion in Hematology. 2003 Jan 1
34 citations
Comprehensive genotypic analysis of leukemia: clinical and therapeutic implications.
Louise M Kelly, Jennifer J. Clark, D. Gary Gilliland> ;Current Opinion in Oncology. 2002 Jan 1
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Hospital Affiliations

Presbyterian/St. Luke's Medical CenterDenver, Colorado
Medical Center of AuroraAurora, Colorado
Sky Ridge Medical CenterLone Tree, Colorado
Swedish Medical CenterEnglewood, Colorado