JenniferK.LittonMD

PubMed

• Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stage II-III breast cancer.
  Sreyashi Basu, Sonali Jindal, Zhong He, Khoi Chu, Akshara Singareeka Raghavendra, Haven R Garber, Clinton Yam, Lumarie Santiago, Beatriz E Adrada, Padmanee Sharma, Eli...> ;Oncotarget. 2024 Mar 19
• Comprehensive Analysis Identifies Variability in PI3K Pathway Alterations in Triple-Negative Breast Cancer Subtypes.
  Reva K Basho, Li Zhao, Jason B White, Lei Huo, Roland L Bassett, Elizabeth A Mittendorf, Alastair Thompson, Jennifer K Litton, Naoto Ueno, Banu Arun, Bora Lim, Vicente...> ;JCO Precision Oncology. 2024 Mar 1
• 1 citations
  Diffusion Tensor Imaging for Characterizing Changes in Triple-Negative Breast Cancer During Neoadjuvant Systemic Therapy.
  Musall, B., Rauch, D., Mohamed, R., Panthi, B., Boge, M., Candelaria, R., Chen, H., Guirguis, M., Hunt, K., Huo, L., Hwang, K., Korkut, A., Litton, J., Moseley, T., Pa...> ;Journal of Magnetic Resonance Imaging. 2024 Jan 31
• Deep Learning for Fully Automatic Tumor Segmentation on Serially Acquired Dynamic Contrast-Enhanced MRI Images of Triple-Negative Breast Cancer.
  Zhan Xu, David E Rauch, Rania M Mohamed, Sanaz Pashapoor, Zijian Zhou, Bikash Panthi, Jong Bum Son, Ken-Pin Hwang, Benjamin C Musall, Beatriz E Adrada, Rosalind P Cand...> ;Cancers. 2023 Oct 2
• Short-Term Biomarker Modulation Study of Dasatinib for Estrogen Receptor-Negative Breast Cancer Chemoprevention.
  Fatma Nihan Akkoc Mustafayev, Diane D Liu, Angelica M Gutierrez, John E Lewis, Nuhad K Ibrahim, Vicente Valero, Daniel J Booser, Jennifer K Litton, Kimberly Koenig, Di...> ;European Journal of Breast Health. 2023 Oct 1
• 5 citations
  Standardized Definitions for Efficacy End Points in Neoadjuvant Breast Cancer Clinical Trials: NeoSTEEP.
  Jennifer K Litton, Meredith M Regan, Lajos Pusztai, Hope S Rugo, Sara M Tolaney, Elizabeth Garrett-Mayer, Laleh Amiri-Kordestani, Reva K Basho, Ana F Best, Jean-Franco...> ;Journal of Clinical Oncology. 2023 Sep 20
• 1 citations
  Predictive Roles of Baseline Stromal Tumor-Infiltrating Lymphocytes and Ki-67 in Pathologic Complete Response in an Early-Stage Triple-Negative Breast Cancer Prospecti...
  Nour Abuhadra, Ryan Sun, Clinton Yam, Gaiane M Rauch, Qingqing Ding, Bora Lim, Alastair M Thompson, Elizabeth A Mittendorf, Beatriz E Adrada, Senthil Damodaran, Kiran ...> ;Cancers. 2023 Jun 21
• 3 citations
  Neoadjuvant Talazoparib in Patients With Germline BRCA1/2 Mutation-Positive, Early-Stage Triple-Negative Breast Cancer: Results of a Phase II Study.
  Jennifer K Litton, J Thaddeus Beck, Jason M Jones, Jay Andersen, Joanne L Blum, Lida A Mina, Raymond Brig, Michael Danso, Yuan Yuan, Antonello Abbattista, Kay Noonan, ...> ;The Oncologist. 2023 Oct 3
• 3 citations
  A phase II study of neoadjuvant atezolizumab and nab-paclitaxel in patients with anthracycline-resistant early-stage triple-negative breast cancer.
  Clinton Yam, Elizabeth A Mittendorf, Haven R Garber, Ryan Sun, Senthil Damodaran, Rashmi K Murthy, David Ramirez, Meghan Karuturi, Rachel M Layman, Nuhad Ibrahim, Gaia...> ;Breast Cancer Research and Treatment. 2023 Jun 1
• Targeting chemotherapy resistance in mesenchymal triple-negative breast cancer: a phase II trial of neoadjuvant angiogenic and mTOR inhibition with chemotherapy.
  Nour Abuhadra, Ryan Sun, Roland L Bassett Jr, Lei Huo, Jeffrey T Chang, Mediget Teshome, Alyson R Clayborn, Jason B White, Elizabeth E Ravenberg, Beatriz E Adrada, Ros...> ;Investigational New Drugs. 2023 Jun 1
• 4 citations
  First-in-human phase I study of the OX40 agonist GSK3174998 with or without pembrolizumab in patients with selected advanced solid tumors (ENGAGE-1).
  Sophie Postel-Vinay, Vincent K Lam, Willeke Ros, Todd M Bauer, Aaron R Hansen, Daniel C Cho, F Stephen Hodi, Jan H M Schellens, Jennifer K Litton, Sandrine Aspeslagh, ...> ;Journal for Immunotherapy of Cancer. 2023 Mar 1
• 7 citations
  Assessment of Response to Neoadjuvant Systemic Treatment in Triple-Negative Breast Cancer Using Functional Tumor Volumes from Longitudinal Dynamic Contrast-Enhanced MRI.
  Bikash Panthi, Beatriz E Adrada, Rosalind P Candelaria, Mary S Guirguis, Clinton Yam, Medine Boge, Huiqin Chen, Kelly K Hunt, Lei Huo, Ken-Pin Hwang, Anil Korkut, Dean...> ;Cancers. 2023 Feb 6
• 6 citations
  Prediction of pathologic complete response to neoadjuvant systemic therapy in triple negative breast cancer using deep learning on multiparametric MRI.
  Zijian Zhou, Beatriz E Adrada, Rosalind P Candelaria, Nabil A Elshafeey, Medine Boge, Rania M Mohamed, Sanaz Pashapoor, Jia Sun, Zhan Xu, Bikash Panthi, Jong Bum Son, ...> ;Scientific Reports. 2023 Jan 20
• Longitudinal dynamic contrast-enhanced MRI radiomic models for early prediction of response to neoadjuvant systemic therapy in triple-negative breast cancer.
  Bikash Panthi, Rania M Mohamed, Beatriz E Adrada, Medine Boge, Rosalind P Candelaria, Huiqin Chen, Kelly K Hunt, Lei Huo, Ken-Pin Hwang, Anil Korkut, Deanna L Lane, Hu...> ;Frontiers in Oncology. 2023 Jan 1
• PTEN in triple-negative breast carcinoma: protein expression and genomic alteration in pretreatment and posttreatment specimens.
  Hui Chen, Qingqing Ding, Laila Khazai, Li Zhao, Senthil Damodaran, Jennifer K Litton, Gaiane M Rauch, Clinton Yam, Jeffrey T Chang, Sahil Seth, Bora Lim, Alastair M Th...> ;Therapeutic Advances in Medical Oncology. 2023 Jan 1
• 14 citations
  MRI-Based Digital Models Forecast Patient-Specific Treatment Responses to Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer.
  Chengyue Wu, Angela M Jarrett, Zijian Zhou, Nabil Elshafeey, Beatriz E Adrada, Rosalind P Candelaria, Rania M M Mohamed, Medine Boge, Lei Huo, Jason B White, Debu Trip...> ;Cancer Research. 2022 Sep 16
• 2 citations
  Tumor Immune Microenvironment Changes by Multiplex Immunofluorescence Staining in a Pilot Study of Neoadjuvant Talazoparib for Early-Stage Breast Cancer Patients with ...
  Tapsi Kumar, Evie Hobbs, Fei Yang, Jeffrey T Chang, Alejandro Contreras, Edwin Roger Parra Cuentas, Haven Garber, Sanghoon Lee, Yiling Lu, Marion E Scoggins, Beatriz E...> ;Clinical Cancer Research. 2022 Sep 1
• 3 citations
  Identification of biomarkers of response to preoperative talazoparib monotherapy in treatment naïve gBRCA+ breast cancers.
  Xuan Liu, Zhongqi Ge, Fei Yang, Alejandro Contreras, Sanghoon Lee, Jason B White, Yiling Lu, Marilyne Labrie, Banu K Arun, Stacy L Moulder, Gordon B Mills, Helen Piwni...> ;NPJ Breast Cancer. 2022 May 10
• 6 citations
  Molecular Characterization and Prospective Evaluation of Pathologic Response and Outcomes with Neoadjuvant Therapy in Metaplastic Triple-Negative Breast Cancer.
  Clinton Yam, Nour Abuhadra, Ryan Sun, Beatriz E Adrada, Qing-Qing Ding, Jason B White, Elizabeth E Ravenberg, Alyson R Clayborn, Vicente Valero, Debu Tripathy, Senthil...> ;Clinical Cancer Research. 2022 Jul 1
• 5 citations
  Quantitative Apparent Diffusion Coefficients From Peritumoral Regions as Early Predictors of Response to Neoadjuvant Systemic Therapy in Triple-Negative Breast Cancer.
  Benjamin C Musall, Beatriz E Adrada, Rosalind P Candelaria, Rania M M Mohamed, Abeer H Abdelhafez, Jong Bum Son, Jia Sun, Lumarie Santiago, Gary J Whitman, Tanya W Mos...> ;Journal of Magnetic Resonance Imaging. 2022 Dec 1
• 10 citations
  Determinants of Response to Talazoparib in Patients with HER2-Negative, Germline BRCA1/2-Mutated Breast Cancer.
  Joanne L Blum, A Douglas Laird, Jennifer K Litton, Hope S Rugo, Johannes Ettl, Sara A Hurvitz, Miguel Martin, Henri H Roché, Kyung-Hun Lee, Annabel Goodwin, Ying Chen,...> ;Clinical Cancer Research. 2022 Apr 1
• 11 citations
  A model combining pretreatment MRI radiomic features and tumor-infiltrating lymphocytes to predict response to neoadjuvant systemic therapy in triple-negative breast c...
  Jorge E Jimenez, Abeer Abdelhafez, Elizabeth A Mittendorf, Nabil Elshafeey, Joshua P Yung, Jennifer K Litton, Beatriz E Adrada, Rosalind P Candelaria, Jason White, Ala...> ;European Journal of Radiology. 2022 Apr 1
• 5 citations
  Prognostic Impact of High Baseline Stromal Tumor-Infiltrating Lymphocytes in the Absence of Pathologic Complete Response in Early-Stage Triple-Negative Breast Cancer.
  Nour Abuhadra, Ryan Sun, Jennifer K Litton, Gaiane M Rauch, Clinton Yam, Jeffrey T Chang, Sahil Seth, Roland Bassett Jr, Bora Lim, Alastair M Thompson, Elizabeth Mitte...> ;Cancers. 2022 Mar 4
• 2 citations
  Application of Artificial Intelligence to Plasma Metabolomics Profiles to Predict Response to Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer.
  Ehsan Irajizad, Ranran Wu, Jody Vykoukal, Eunice Murage, Rachelle Spencer, Jennifer B Dennison, Stacy Moulder, Elizabeth Ravenberg, Bora Lim, Jennifer Litton, Debu Tri...> ;Frontiers in Artificial Intelligence. 2022 Jan 1
• 9 citations
  Effector memory cytotoxic CD3+/CD8+/CD45RO+ T cells are predictive of good survival and a lower risk of recurrence in triple-negative breast cancer.
  Xiangjie Sun, Jie Zhai, Baohua Sun, Edwin R. Parra, Mei Jiang, Wencai Ma, Jing Wang, Anthony M Kang, Kasthuri Kannan, Renganayaki Krishna Pandurengan, Shanyu Zhang, Lu...> ;Modern Pathology. 2021 Nov 27
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Lectures

• Germline Testing in the PARP Inhibitor Era 
  ASCO Annual Meeting 2019 - Chicago, IL - 6/3/2019
• Neoadjuvant talazoparib (TALA) for operable breast cancer patients with a BRCA mutation (BRCA+). 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/4/2018

Other

• Breast cancer during pregnancy and lactation: Epidemiology and diagnosis 
  Litton JK, Theriault R
  http://www.uptodate.com/contents/breast-cancer-during-pregnancy-and-lactation-epidemiology-and-diagn
  UpToDate, Wolters Kluwer Health - 2012-05-15
• Breast cancer during pregnancy and lactation: Treatment 
  Litton JK, Theriault R
  http://www.uptodate.com/contents/breast-cancer-during-pregnancy-and-lactation-treatment
  UpToDate, Wolters Kluwer Health - 2013-01-07