JeraldChasSadoffMD

PubMed

• 20 citations
  Safety and Immunogenicity of Adenovirus 35 Tuberculosis Vaccine Candidate in Adults with Active or Previous Tuberculosis. A Randomized Trial
  Richard N. van Zyl-Smit, Aliasgar Esmail, Mary Bateman, Rodney Dawson, Jonathan G. Goldin, Eva M. van Rikxoort, Macaya Douoguih, Maria Grazia Pau, Jerald C. Sadoff, J....> ;American Journal of Respiratory and Critical Care Medicine. 2017 May 1
• 188 citations
  Systems analysis of protective immune responses to RTS,S malaria vaccination in humans
  Dmitri Kazmin, Helder I. Nakaya, Eva K. Lee, Matthew Johnson, Robbert van der Most, Robert A. van den Berg, W. Ripley Ballou, Erik Jongert, Ulrike Wille-Reece, Christi...> ;Proceedings of the National Academy of Sciences of the United States of America. 2017 Feb 28
• 15 citations
  Adenovirally-Induced Polyfunctional T Cells Do Not Necessarily Recognize the Infected Target: Lessons from a Phase I Trial of the AERAS-402 Vaccine.
  Melissa Nyendak, Gwendolyn Swarbrick, Amanda Duncan, Meghan E. Cansler, Ervina Winata Huff, David A. Hokey, Thomas J. Evans, Lewellys F. Barker, Gretta L Blatner, Jera...> ;Scientific Reports. 2016 Nov 2
• 9 citations
  Adenovirus type 35-vectored tuberculosis vaccine has an acceptable safety and tolerability profile in healthy, BCG-vaccinated, QuantiFERON(®)-TB Gold (+) Kenyan adults...
  Douglas S. Walsh, Victorine Owira, Mark E. Polhemus, Lucas Otieno, Ben Andagalu, Bernhards Ogutu, John Waitumbi, Anthony Hawkridge, Barbara Shepherd, Maria Grazia Pau,...> ;Vaccine. 2016 May 5
• 28 citations
  A Phase I, Open-Label Trial, Evaluating the Safety and Immunogenicity of Candidate Tuberculosis Vaccines AERAS-402 and MVA85A, Administered by Prime-Boost Regime in BC...
  Sharon Sheehan, Stephanie A. Harris, Iman Satti, David A. Hokey, Veerabadran Dheenadhayalan, Lisa Stockdale, Zita-Rose Manjaly Thomas, Alice Minhinnick, Morven Wilkie,...> ;Plos One. 2015 Nov 3
• A double-blind, randomised, placebo-controlled, dose-finding trial of the novel tuberculosis vaccine AERAS-402, an adenovirus-vectored fusion protein, in healthy, BCG-...
  Tameris M, Hokey DA, Nduba V, Sacarlal J, Laher F, Kiringa G, Gondo K, Lazarus EM, Gray GE, Nachman S, Mahomed H, Downing K, Abel B, Scriba TJ, McClain JB, Pau MG, Hen...> ;Vaccine. 2015-06-09
• 7 citations
  Immunogenicity without Efficacy of an Adenoviral Tuberculosis Vaccine in a Stringent Mouse Model for Immunotherapy during Treatment
  S. Anisah Alyahya, Scott Nolan, Cara M. R. Smith, William R. Bishai, Jerald C. Sadoff, Gyanu Lamichhane> ;Plos One. 2015 May 21
• 35 citations
  The Novel Tuberculosis Vaccine, AERAS-402, Is Safe in Healthy Infants Previously Vaccinated With BCG, and Induces Dose-Dependent CD4 and CD8T Cell Responses
  Benjamin M. Kagina, Michele Tameris, Hennie Geldenhuys, Mark Hatherill, Brian Abel, Gregory D. Hussey, Thomas J. Scriba, Hassan Mahomed, Jerald C. Sadoff, Willem A. Ha...> ;Vaccine. 2014 Oct 14
• 73 citations
  Aerosol Vaccination with AERAS-402 Elicits Robust Cellular Immune Responses in the Lungs of Rhesus Macaques but Fails To Protect against High-Dose Mycobacterium tuberc...
  Patricia A. Darrah, Diane L. Bolton, Andrew A. Lackner, Deepak Kaushal, Pyone P. Aye, Smriti Mehra, James Blanchard, Peter J. Didier, Chad J. Roy, Srinivas S. Rao, Dav...> ;Journal of Immunology. 2014 Aug 15
• 20 citations
  A nonhuman primate toxicology and immunogenicity study evaluating aerosol delivery of AERAS-402/Ad35 vaccine: Evidence for transient t cell responses in peripheral blo...
  David A. Hokey, Robert Wachholder, Patricia A. Darrah, Diane L Bolton, Dan H. Barouch, Krystal Hill, Veerabadran Dheenadhayalan, Stephan Schwander, C Steven Godin, Mac...> ;Human Vaccines & Immunotherapeutics. 2014 May 8
• A nonhuman primate toxicology and immunogenicity study evaluating aerosol delivery of AERAS-402/Ad35 Vaccine: Evidence for transient t cell responses in peripheral blo...
  Hokey, D. A.,Wachholder, R.,Darrah, P. A.,Bolton, D. L.,Barouch, D. H.,Hill, K.,Dheenadhayalan, V.,Schwander, S.,Godin, C. S.,Douoguih, M.,Pau, M. G.,Seder, R. A.,Roed...> ;Hum Vaccin Immunother. 2014 May 09
• 44 citations
  Systematic evaluation of in vitro and in vivo adventitious virus assays for the detection of viral contamination of cell banks and biological products.
  James Gombold, Stephen Karakasidis, Paula Niksa, John Podczasy, Kitti Neumann, James A. Richardson, Nandini Sane, Renita Johnson-Leva, Valerie B. Randolph, Jerald C. S...> ;Vaccine. 2014 May 19
• 39 citations
  A Phase 1b Randomized, Controlled, Double-Blinded Dosage-Escalation Trial to Evaluate the Safety, Reactogenicity and Immunogenicity of an Adenovirus Type 35 Based Circ...
  Alphonse Ouedraogo, Alfred B. Tiono, Désiré Kargougou, Jean Baptiste Yaro, Espérance Ouédraogo, Youssouf Kaboré, David T. Kangoye, Edith C. Bougouma, Adama Gansané, No...> ;Plos One. 2013 Nov 11
• 89 citations
  Induction and regulation of T-cell immunity by the novel tuberculosis vaccine M72/AS01 in South African adults.
  Cheryl L. Day, Michele Tameris, Nazma Mansoor, Michele van Rooyen, Marwou de Kock, Hennie Geldenhuys, Mzwandile Erasmus, Lebohang Makhethe, E. Jane Hughes, Sebastian G...> ;American Journal of Respiratory and Critical Care Medicine. 2013 Aug 15
• 71 citations
  A recombinant adenovirus expressing immunodominant TB antigens can significantly enhance BCG-induced human immunity.
  Daniel F. Hoft, Azra Blazevic, Jaime Stanley, Bernard Landry, Donata Sizemore, Eloi Kpamegan, Jacqueline Gearhart, Alison J. Scott, Sandra V. Kik, Maria G. Pau, Jaap G...> ;Vaccine. 2012 Mar 9
• 400 citations
  Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys
  Dan H. Barouch, Jinyan Liu, Hualin Li, Lori F. Maxfield, Peter Abbink, Diana M. Lynch, M. Justin Iampietro, Adam J. SanMiguel, Michael S. Seaman, Guido Ferrari, Donald...> ;Nature. 2012 Feb 2
• 26 citations
  Optimizing HIV-1-specific CD8+ T-cell induction by recombinant BCG in prime-boost regimens with heterologous viral vectors
  Richard Hopkins, Anne Bridgeman, Charles Bourne, Alice Mbewe-Mvula, Jerald C. Sadoff, Gerald W. Both, Joan Joseph, John Fulkerson, Tomáš Hanke> ;European Journal of Immunology. 2011 Dec 1
• 54 citations
  Genetic immunization in the lung induces potent local and systemic immune responses
  Kaimei Song, Diane L. Bolton, Chih-Jen Wei, Robert L. Wilson, Jeremy V. Camp, Saran Bao, Joseph J. Mattapallil, Leonore A. Herzenberg, Leonard A. Herzenberg, Charla A....> ;Proceedings of the National Academy of Sciences of the United States of America. 2010 Dec 21
• 36 citations
  Stabilizing formulations for inhalable powders of an adenovirus 35-vectored tuberculosis (TB) vaccine (AERAS-402).
  Tom H. Jin, Eric Tsao, Jaap Goudsmit, Veerabadran Dheenadhayalan, Jerald C. Sadoff> ;Vaccine. 2010 Jun 17
• 23 citations
  Safety and Immunogenicity of Novel Recombinant BCG and Modified Vaccinia Virus Ankara Vaccines in Neonate Rhesus Macaques
  Maximillian Rosario, John Fulkerson, Shamit Soneji, Joe Parker, Eung Jun Im, Nicola Borthwick, Anne Bridgeman, Charles Bourne, Joan Joseph, Jerald C. Sadoff, Tomáš Hanke> ;Journal of Virology. 2010 Aug 1
• 35 citations
  Update on Research and Development Pipeline: Tuberculosis Vaccines
  Belinda Beresford, Jerald C. Sadoff> ;Clinical Infectious Diseases. 2010 May 15
• 20 citations
  Novel recombinant Mycobacterium bovis BCG, ovine atadenovirus, and modified vaccinia virus Ankara vaccines combine to induce robust human immunodeficiency virus-specif...
  Maximillian Rosario, Richard Hopkins, John Fulkerson, Nicola Borthwick, Máire F. Quigley, Joan Joseph, Daniel C. Douek, Hui Yee Greenaway, Vanessa Venturi, Emma Gostic...> ;Journal of Virology. 2010 Jun 15
• The second Geneva Consensus: Recommendations for novel live TB vaccines.
  Walker KB, Brennan MJ, Ho MM, Eskola J, Thiry G, Sadoff J, Dobbelaer R, Grode L, Liu MA, Fruth U, Lambert PH> ;Vaccine. 2010-03-08
• 175 citations
  The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults
  Brian Abel, Michele Tameris, Nazma Mansoor, Sebastian Gelderbloem, Jane Hughes, Deborah Abrahams, Lebohang Makhethe, Mzwandile Erasmus, Marwou de Kock, Linda van der M...> ;American Journal of Respiratory and Critical Care Medicine. 2010 Jun 15
• 43 citations
  Recombinant Yellow Fever Vaccine Virus 17D Expressing Simian Immunodeficiency Virus SIVmac239 Gag Induces SIV-Specific CD8+ T-Cell Responses in Rhesus Macaques
  Myrna C. Bonaldo, Mauricio A. Martins, Richard Rudersdorf, Philip A. Mudd, Jonah B. Sacha, Shari M. Piaskowski, Patrícia Cristina da Costa Neves, Marlon G. Veloso de S...> ;Journal of Virology. 2010 Apr 1
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Journal Articles

• Interim Results of a Phase 1–2a Trial of Ad26.COV2.S Covid-19 Vaccine  
  Jerald Sadoff, Kathryn E Stephenson, Dan H Barouch, Macaya Douoguih, The New England Journal of Medicine