JeremieHeathEsteppMD

PubMed

• 1 citations
  Intensive hydroxyurea dosing in very young children with sickle cell anemia.
  Winfred C Wang, R Clark Brown, Melissa A McNaull, Zora R Rogers, Martha Barton, Meghna R Dua, Jane S Hankins, Jeffrey Gossett, Julie Richardson, Jerlym S Porter, Guoli...> ;Blood Advances. 2023 Nov 28
• 2 citations
  Genetic Variation and Sickle Cell Disease Severity: A Systematic Review and Meta-Analysis.
  Justin K Kirkham, Jeremie H Estepp, Mitch J Weiss, Sara R Rashkin> ;JAMA Network Open. 2023 Oct 2
• Genomic analysis of venous thrombosis in children with acute lymphoblastic leukemia from diverse ancestries.
  Yan Zheng, Wenjian Yang, Jeremie Estepp, Deqing Pei, Cheng Cheng, Clifford M Takemoto, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Mary V Relling, Seth E Karol> ;Haematologica. 2024 Jan 1
• Leveraging mathematical modeling to analyze nonadherence for hydroxyurea therapy in sickle cell disease.
  Akancha Pandey, Rubesh Raja, Jeremie H Estepp, Doraiswami Ramkrishna> ;CPT. 2023 Jun 1
• 1 citations
  Working memory and school readiness in preschool children with sickle cell disease compared to demographically matched controls.
  Andrew M Heitzer, Jane E Schreiber, Xiaomeng Yuan, Fang Wang, Haitao Pan, J Carolyn Graff, Laura Murphy, Rebecca Rupff, Kathryn Russell, Winfred Wang, Jeremie H Estepp...> ;British Journal of Haematology. 2023 Feb 1
• 1 citations
  A clinician's view of voxelotor.
  Ifeyinwa Osunkwo, Alan Anderson, R Clark Brown, Nirmish Shah, Jeremie H Estepp> ;British Journal of Haematology. 2022 Nov 1
• 7 citations
  Host Predictors of Broadly Cross-Reactive Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variants of Concern Differ Between Infection ...
  Li Tang, Sean Cherry, Elaine I Tuomanen, Ericka Kirkpatrick Roubidoux, Chun Yang Lin, Kim J Allison, Ashleigh Gowen, Pamela Freiden, E Kaitlynn Allen, Yin Su, Aditya H...> ;Clinical Infectious Diseases. 2022 Aug 24
• 20 citations
  Safety and efficacy of voxelotor in pediatric patients with sickle cell disease aged 4 to 11 years.
  Jeremie H Estepp, Ram Kalpatthi, Gerald Woods, Sara Trompeter, Robert I Liem, Kacie Sims, Adlette Inati, Baba P D Inusa, Andrew Campbell, Connie Piccone, Miguel R Abbo...> ;Pediatric Blood & Cancer. 2022 Aug 1
• 5 citations
  Fetal hemoglobin modulates neurocognitive performance in sickle cell anemia.
  Andrew M Heitzer, Jennifer Longoria, Evadnie Rampersaud, Sara R Rashkin, Jeremie H Estepp, Victoria I Okhomina, Winfred C Wang, Darcy Raches, Brian Potter, Martin H St...> ;Current Research in Translational Medicine. 2022 Jul 1
• 15 citations
  PARIS and SPARTA: Finding the Achilles' Heel of SARS-CoV-2.
  Viviana Simon, Vamsi Kota, Ryan F Bloomquist, Hannah B Hanley, David Forgacs, Savita Pahwa, Suresh Pallikkuth, Loren G Miller, Joanna Schaenman, Michael R Yeaman, Davi...> ;Msphere. 2022 Jun 29
• 1 citations
  Mathematical Modeling of Hydroxyurea Therapy in Individuals with Sickle Cell Disease.
  Akancha Pandey, Jeremie H Estepp, Rubesh Raja, Guolian Kang, Doraiswami Ramkrishna> ;Pharmaceutics. 2022 May 16
• 67 citations
  SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8T cells.
  Anastasia A Minervina, Mikhail V Pogorelyy, Allison M Kirk, Jeremy Chase Crawford, E Kaitlynn Allen, Ching-Heng Chou, Robert C Mettelman, Kim J Allison, Chun-Yang Lin,...> ;Nature Immunology. 2022 May 1
• 4 citations
  Strategies to increase access to basic sickle cell disease care in low- and middle-income countries.
  Meghna Dua, Halima Bello-Manga, Yvonne M Carroll, Aisha Amal Galadanci, Umma Abdulsalam Ibrahim, Allison A King, Ayobami Olanrewaju, Jeremie H Estepp> ;Expert Review of Hematology. 2022 Apr 1
• 1 citations
  GMEPS: a fast and efficient likelihood approach for genome-wide mediation analysis under extreme phenotype sequencing.
  Janaka S S Liyanage, Jeremie H Estepp, Kumar Srivastava, Yun Li, Motomi Mori, Guolian Kang> ;Statistical Applications in Genetics and Molecular Biology. 2022 Mar 11
• 7 citations
  Neurocognitive functioning in preschool children with sickle cell disease.
  Andrew M Heitzer, Diana L Cohen, Victoria I Okhomina, Ana Trpchevska, Brian Potter, Jennifer Longoria, Jerlym S Porter, Jeremie H Estepp, Allison King, Misham Henley, ...> ;Pediatric Blood & Cancer. 2022 Mar 1
• 52 citations
  Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response.
  Chun-Yang Lin, Joshua Wolf, David C Brice, Yilun Sun, Macauley Locke, Sean Cherry, Ashley H Castellaw, Marie Wehenkel, Jeremy Chase Crawford, Veronika I Zarnitsyna, Da...> ;Cell Host & Microbe. 2022 Jan 12
• 11 citations
  An Assessment of Serological Assays for SARS-CoV-2 as Surrogates for Authentic Virus Neutralization.
  Nicholas Wohlgemuth, Kendall T Whitt, Sean Cherry, Ericka Kirkpatrick Roubidoux, Chun-Yang Lin, Kim J Allison, Ashleigh Gowen, Pamela Freiden, E. Kaitlynn Allen, St. J...> ;Microbiology Spectrum. 2021 Oct 27
• 8 citations
  A reanalysis of pain crises data from the pivotal l-glutamine in sickle cell disease trial.
  Ahmar U. Zaidi, Jeremie H. Estepp, Nirmish Shah, Salam Alkindi, Hatoon Ezzat, Hung Lam, Caterina P. Minniti> ;Contemporary Clinical Trials. 2021 Sep 10
• 11 citations
  Cross-reactive Antibody Response to mRNA SARS-CoV-2 Vaccine After Recent COVID-19-Specific Monoclonal Antibody Therapy.
  Stacey Schultz-Cherry, Maureen A. McGargill, Paul G. Thomas, Jeremie H. Estepp, Aditya H. Gaur, E. Kaitlynn Allen, Kim J Allison, Li Tang, Richard J. Webby, Sean Cherr...> ;Open Forum Infectious Diseases. 2021 Aug 10
• 4 citations
  Progression of central nervous system disease from pediatric to young adulthood in sickle cell anemia
  Grace Champlin, Scott N. Hwang, Andrew M. Heitzer, Juan Ding, Lisa M. Jacola, Jeremie H. Estepp, Winfred C. Wang, Kenneth I. Ataga, Curtis L. Owens, Justin Newman, All...> ;Experimental Biology and Medicine. 2021 Aug 18
• 3 citations
  Developmental screening of three-year-old children with sickle cell disease compared to controls.
  Winfred C. Wang, Molly Beth Freeman, Latacha Hamilton, Yvonne Carroll, Guolian Kang, Joseph Moen, Matthew P. Smeltzer, Jane E. Schreiber, Andrew M. Heitzer, Jeremie H....> ;British Journal of Haematology. 2021 Aug 15
• 44 citations
  Convergent epitope-specific T cell responses after SARS-CoV-2 infection and vaccination
  Anastasia A. Minervina, Mikhail V. Pogorelyy, Allison M Kirk, E.K. Allen, Kim J Allison, Chung-Yang Lin, David C. Brice, Xun Zhu, Kasi Vegesana, Gang Wu, Jeremy Chase ...> ;Medrxiv. 2021 Jul 27
• 11 citations
  A polygenic score for acute vaso-occlusive pain in pediatric sickle cell disease
  Evadnie Rampersaud, Guolian Kang, Lance E. Palmer, Sara R. Rashkin, Shuoguo Wang, Wenjian Bi, Nicole M. Alberts, Doralina L. Anghelescu, Martha Barton, Kirby Birch, Ni...> ;Blood Advances. 2021 Jul 27
• 2 citations
  Generalization of a genetic risk score for time to first albuminuria in children with sickle cell anaemia: SCCRIP cohort study results.
  Sara R. Rashkin, Evadnie Rampersaud, Guolian Kang, Kenneth I. Ataga, Jane S. Hankins, Winfred C. Wang, Jeremie H. Estepp, Mitchell J. Weiss, Jeffrey D. Lebensburger, R...> ;British Journal of Haematology. 2021 Jun 16
• 6 citations
  What drives transcranial Doppler velocity improvement in paediatric sickle cell anaemia: analysis from the Sickle Cell Clinical Research and Intervention Program (SCCR...
  Jeremie H. Estepp, Ze Cong, Irene Agodoa, Guolian Kang, Juan Ding, M. Beth McCarville, Jane S. Hankins, Winfred C. Wang> ;British Journal of Haematology. 2021 Jun 15
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Journal Articles

• A Clinically Meaningful Fetal Hemoglobin Threshold for Children with Sickle Cell Anemia During Hydroxyurea Therapy  
  Estepp JH, Smeltzer MP, Kang G, Aygun B, Abrams C, Wang W, Ware RE, Nottage K, Hankins J, American Journal of Hematology, 1/1/2017

Books/Book Chapters

• The Eye in Pediatric Systemic Disease 
  Chapter: Hematologic disorders of the eye. 
  Hoehn ME, Elder JE and Estepp JHSpringer International Publishing, New York, NYEdition 1st,2017
• Keeling's Fetal and Neonatal Pathology 
  Chapter: Perinatal Hematology 
  Choi JK and Estepp JHSpringer International Publishing, New York, NYEdition 5th,2016
• Sickle Cell Anemia: From Basic Science to Clinical Practice 
  Chapter: Future Perspectives for the Treatment of Sickle Cell Disease. 
  Nottage KA, Estepp JH, Hankins JSSpringer International Publishing, New York, NY2016

Abstracts/Posters

• Disease Modeling and Phenotype Rescue Using Inducible Pluripotent Stem Cells from Patients with Diamond-Blackfan Anemia
  Jeremie H. Estepp, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Progression of Central Nervous System Vasculopathy in Young Adults with Sickle Cell Anemia
  Jeremie H. Estepp, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Phase 1 Single (SAD) and Multiple Ascending Dose (MAD) Studies of the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of FT-4202, an Allosteric A...
  Jeremy H. Estepp, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Cognitive function in preschool-aged children with sickle cell disease: associations with home environment and disease-severity.
  Schreiber JE, Beaulieu R, White L, Hall L, Estepp JH, Wang WC, 45th Annual Meeting: International Neuropsychological Society, New Orleans, LA, 1/1/2017
• Neurocognitive Functioning in Preschool Children with Sickle Cell Disease.
  Schreiber JE, Ali JS, Jurbergs N, Ehrentraut JH, Estepp JH, Boggs J, Aygun B, Wang WC, Annual Society of Pediatric Psychology Meeting, Portland, OR, 1/1/2017
• The Pharmacokinetics (PK) of GBT440 are Similar in Adolescents and Adults with Sickle Cell Disease (SCD).
  Washington C; Savic R, Inati A; Estepp JH; Woods G; Fong E; Hutchaleelaha A; Tonda M; Balaratnam G; Lehrer-Graiwer J, 22nd Congress of the European Hematology Association, Madrid, Spain, 1/1/2017
• Trends in Hospitalization Rates in a Prospective Cohort of Pediatric Sickle Cell Disease Patients on Hydroxyurea Therapy.
  Meadows MB; Smeltzer MP; Hankins J; Estepp JH, 2017 Annual Meeting of the American College of Epidemiology, New Orleans, LA, 1/1/2017
• Neurocognitive Functioning Among Young Patients with Sickle Cell Disease: Associations with Demographic and Disease-Related Factors.
  Ali JS, Schreiber JE, Ehrentraut J, Jurbergs N, Estepp JH, Martin J, Aygun B, Wang WC, International Neuropsychological Society Annual Meeting, Boston, MA, 1/1/2016
• Whole Genome Sequence Analysis of Fetal Hemoglobin in African American Sickle Cell Patients.
  Rampersaud E, Kang G, Yasui Y, Wang S, Feng R, Estepp JH, Zhang J, Hankins J, Wu G, Weiss M, 13th Annual Meeting: International Congress of Human Genetics, Kyoto, Japan, 1/1/2016
• Hydroxyurea at maximal tolerated dose (MTD) prior to completion of the Beta-globin switch has additive but not sustained benefits in fetal hemoglobin production.
  Abrams C, Moen J, Kang K, Wang WC, Hankins J, Estepp JH, 58th Annual Meeting: American Society of Hematology, San Diego, CA, 1/1/2016
• Pharmacokinetics in children with sickle cell anemia following single dose versus chronic treatment with hydroxyurea.
  Mack MJ, Wiczling P, Moen J, Kang G, Liem RI, Panepinto JA, Kearns GK, Neville KA, Estepp JH, 58th Annual Meeting: American Society of Hematology, San Diego, CA, 1/1/2016
• Clinical and laboratory features of hemoglobin S/(A/gamma/delta/Beta)0-thalassemia.
  Cancio MI, Aygun B, Chui DH, Estepp JH, Smeltzer MP, Hankins JS, 58th Annual Meeting: American Society of Hematology, San Diego, CA, 1/1/2016
• Re-Aiming at Hydroxyurea Adherence for Sickle Cell with mHealth (Re-HASH).
  Hankins J, Gurney J, Porter J, Kang G, Carroll Y, Hodges J, Alberts N, Smeltzer M, Hamayouni R, DeBon M, Osarogiabon R, Cooper W, Debaun M, Estepp JH, Weiss M, Klesges L, Faculty/Postdoctoral Poster Research Day, St. Jude Children's Hospital, Memphis, TN, 1/1/2016
• Brigance Preschool Screen II and Neurocognitive Functioning Among Young Patients with Sickle Cell Disease.
  Ali JS, Schreiber JE, Ehrentraut J, Jurbergs N, Estepp JH, Martin J, Aygun B, Wang WC, Society for Developmental and Behavioral Pediatrics, Las Vegas, NV, 1/1/2015
• Prognostic Factors for Hospitalization of Children with Sickle Cell Anemia Treated with Hydroxyurea at Maximum Tolerated Dose.
  Estepp JH, Huan Q, Wang WC, Kang G, 57th Annual Meeting: American Society of Hematology, Orlando, FL, 1/1/2015
• Intensification of hydroxyurea therapy in young children with sickle cell anemia.
  Estepp JH, Smeltzer MP, Lian S, Kang GK, Wang WC, 8th Annual Sickle Cell Disease Research and Educational Symposium and 37th National Sickle Cell Disease Scientific Meeting, Miami, FL, 1/1/2014
• Improved adherence to hydroxyurea in children with sickle cell anemia utilizing text messages.
  Estepp JH, Johnson M, Smeltzer MP, Winter B, Carroll Y, Hankins JS, 2th Annual Global Sickle Cell Anemia Congress, Rio de Janeiro, Brazil, 1/1/2014
• Escalating doses of hydroxyurea in very young children with sickle cell anemia.
  Estepp JH, Wang WC, 2th Annual Global Sickle Cell Anemia Congress, Rio de Janeiro, Brazil, 1/1/2014
• Improved adherence to hydroxyurea in children with sickle cell anemia utilizing text messages.
  Estepp JH, Johnson M, Smeltzer MP, Winter B, Carroll Y, Hankins JS, 26th Annual Meeting: American Society of Pediatric Hematology and Oncology, Miami, FL, 1/1/2013
• Traumatic lumbar punctures in children receiving low-molecular-weight heparin during treatment for acute lymphoblastic leukemia or lymphoma.
  Estepp JH, Smeltzer MP, Howard SC, Reiss UM, Faculty/Postdoctoral Poster Research Day, St. Jude Children's Hospital, Memphis, TN, 1/1/2013
• Escalating doses of hydroxyurea in very young children with sickle cell anemia.
  Lian S, Estepp JH, Wang WC, 55th Annual Meeting: American Society of Hematology, 1/1/2013
• Effect of "therapeutic" anticoagulation with low-molecular-weight-heparin on recurrent venous thrombosis in children.
  Estepp JH, Smeltzer M, Reiss UM, 4th Annual Pediatric Research Day, Memphis, TN, 1/1/2011
• The impact of hydroxyurea therapy on the prevalence of retinopathy in a pediatric sickle cell cohort.
  Estepp JH, Smeltzer M, Aygun B, 53rd Annual Meeting: American Society of Hematology, 1/1/2011
• Effect of "therapeutic" anticoagulation with low-molecular-weight-heparin on recurrent venous thrombosis in children.
  Estepp JH, Smeltzer M, Reiss UM, 24th Annual Meeting: American Society of Pediatric Hematology and Oncology, 1/1/2011
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Lectures

• Transcranial Doppler Velocities Conversion Rate Based on Increasing Hemoglobin Concentration: Analysis from the SCCRIP Cohort Study 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Fetal Hemoglobin Level during Hydroxyurea Therapy Varies By Neighborhood 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Effects of Hydroxyurea on Neurocognitive Performance in Children with Sickle Cell Disease: A Prospective Trial. 
  Atlanta, GA - 1/1/2018
• "FDA Approved Disease Modifiers" 
  Washington University School of Medicine, St. Louis, MO - 1/15/2017
• Hydroxyurea at Maximal Tolerated Dose (MTD) Prior to Completion of the Beta-globin Switch Has Additive but Not Sustained Benefits in Fetal Hemoglobin Production. 
  San Diego, CA - 1/1/2017
• "Hydroxyurea Therapy in Sickle Cell Disease" 
  St. Jude Children's Research Hospital, Memphis, TN - 1/21/2016
• Statistical Exploration of How Multiple Enhancers Affect Traits Jointly. 
  Kyoto, Japan - 1/1/2016
• "Sickle Cell Disease: Advances in Therapy" 
  Memphis, TN - 1/16/2015
• "Coagulation: What the ABP Thinks You Should Know" 
  Memphis, TN - 1/7/2015
• "What is the Optimal Hydroxyurea Dosing?" 
  Atlanta, GA - 1/28/2014
• "Hope for Hydroxyurea" 
  Indianapolis, IN - 1/25/2014
• "Moving Forward in Sickle Cell Disease" 
  Memphis, TN - 1/17/2014
• "Infants with Sickle Cell Disease and Hydroxyurea" 
  Rio de Janeiro, Brazil - 1/10/2014
• "Pediatric Venous Thrombosis" 
  Memphis, TN - 1/8/2014
• Higher fetal hemoglobin in children treated with hydroxyurea at maximum tolerated dose provides additional clinical benefits. 
  San Francisco, CA - 1/1/2014
• "Sickle Cell Disease" 
  Memphis, TN - 1/10/2013
• Traumatic lumbar punctures in children receiving low-molecular-weight heparin during treatment for acute lymphoblastic leukemia or lymphoma. 
  Amsterdam, Netherlands - 1/1/2013
• "Cerebral Venous Sinus Thrombosis in Neuro-Oncology Patients" 
  St. Jude Children's Research Hospital, Memphis, TN - 1/10/2011
• "Intracranial Hemorrhage in Children with Hemophilia" 
  St. Jude Children's Research Hospital, Memphis, TN - 1/1/2011
• "STOP I Trial-CVA in Sickle Cell Anemia" 
  St. Jude Children's Research Hospital, Memphis, TN - 1/1/2011
• "Emergency Care Issues in Hemophilia" 
  St. Jude Children's Research Hospital, Memphis, TN - 1/20/2010
• "Hemostasis in Malignancy" 
  St. Jude Children's Research Hospital, Memphis, TN - 1/12/2010
• "Cerebral Venous Sinus Thrombosis and Leukemia: The Cross-Roads" 
  St. Jude Children's Research Hospital, Memphis, TN - 1/1/2009
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