JethroL.HuMD

Neurology • Los Angeles, CA

Neurooncology

Physician

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Office
127 S San Vicente Blvd
Ste A6600
Los Angeles, CA 90048
Phone+1 310-423-8100

Fax+1 310-967-8739
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Education & Training

UCLA David Geffen School of Medicine/UCLA Medical CenterResidency, Neurology, 2005 - 2008
Santa Clara Valley Medical CenterResidency, Internal Medicine, 2004 - 2005
University of California San Francisco School of MedicineClass of 2004

Certifications & Licensure

CA State Medical License 2006 - 2026
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Clinical Trials

Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma Start of enrollment: 2009 Sep 01
Recruiting
Phase 3
Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma Start of enrollment: 2014 Jan 08
Completed
Phase 1
Ketogenic Diet in Combination With Standard-of-care Radiation and Temozolomide for Patients With Glioblastoma Start of enrollment: 2018 Apr 13
Active, not recruiting
Phase 1
Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM Start of enrollment: 2020 Dec 08
Active, not recruiting
Not Applicable
Roles: Contact
Study of Tirabrutinib (ONO-4059) in Patients With Primary Central Nervous System Lymphoma (PROSPECT Study) Start of enrollment: 2021 Dec 29
Recruiting
Phase 2
Roles: Contact, Principal Investigator
A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatment Start of enrollment: 2023 Jun 27
Recruiting
Phase 2
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

Long-term survival after salvage pemetrexed for refractory primary T-cell lymphoma of the CNS.
Andy Liu, Huda Alalami, Xuemo Fan, Chirag Patil, Jaya M Gill, Santosh Kesari, Jethro Hu> ;CNS Oncology. 2023 Sep 1
Very long-term survival of an older glioblastoma patient after treatment with cilengitide: a case report.
Huda Alalami, Serguei Bannykh, Xuemo Fan, Jethro Hu> ;CNS Oncology. 2023 Jun 1
35 citations
A Phase I Study of Autologous Dendritic Cell Vaccine Pulsed with Allogeneic Stem-like Cell Line Lysate in Patients with Newly Diagnosed or Recurrent Glioblastoma.
Jethro Hu, Oluwaseun Adeola Omofoye, Jeremy Rudnick, Sungjin Kim, Mourad Tighiouart, Surasak Phuphanich, Hongqiang Wang, Mia Mazer, Toni Ganaway, Ray M Chu, Chirag G. ...> ;Clinical Cancer Research. 2021 Dec 3
33 citations
Myxoid glioneuronal tumor, PDGFRA p.K385-mutant: clinical, radiologic, and histopathologic features.
Calixto-Hope G Lucas, Javier Villanueva-Meyer, Nicholas S Whipple, Nancy Ann Oberheim Bush, Tabitha Cooney, Susan M. Chang, Michael W. McDermott, Mitchel S. Berger, El...> ;Brain Pathology. 2020 May 1
26 citations
A phase I trial of surgical resection with Gliadel Wafer placement followed by vaccination with dendritic cells pulsed with tumor lysate for patients with malignant gl...
Jeremy Rudnick, J. Manuel Sarmiento, Benjamin R. Uy, Miriam A Nuno, Christopher J. Wheeler, Mia Mazer, Hongqiang Wang, Jethro Hu, Ray M Chu, Surasak Phuphanich, Keith ...> ;Journal of Clinical Neuroscience. 2020 Apr 1
3 citations
Clinical response to pazopanib in a patient with endolymphatic sac tumor not associated with von Hippel-Lindau syndrome.
Thomas R. Nelson, Jethro Hu, Serguei Bannykh, Xuemo Fan, Jeremy Rudnick, Eric Vail> ;CNS Oncology. 2020 Mar 1
Corrigendum: Exploring the Feasibility and Effects of a Ketogenic Diet in Patients With CNS Malignancies: A Retrospective Case Series.
Cristina M Panhans, Gillian Gresham, L J Amaral, Jethro Hu> ;Frontiers in Neuroscience. 2020 Jan 1
12 citations
Exploring the Feasibility and Effects of a Ketogenic Diet in Patients With CNS Malignancies: A Retrospective Case Series.
Cristina M Panhans, Gillian Gresham, L J Amaral, Jethro Hu> ;Frontiers in Neuroscience. 2020 Jan 1
152 citations
Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial.
E. Antonio Chiocca, John S. Yu, Rimas V. Lukas, Isaac H. Solomon, Keith L. Ligon, Hiroshi Nakashima, Daniel Triggs, David A. Reardon, Patrick Y. Wen, Brittany M. Stopa...> ;Science Translational Medicine. 2019 Aug 14
52 citations
Blockade of a Laminin-411-Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk.
Tao Sun, Rameshwar Patil, Anna Galstyan, Dmytro Klymyshyn, Hui Ding, Alexandra Chesnokova, Webster K. Cavenee, Frank B. Furnari, Vladimir A. Ljubimov, Ekaterina S. Sha...> ;Cancer Research. 2019 Mar 15
28 citations
Profiles of brain metastases: Prioritization of therapeutic targets
Sherise D. Ferguson, Siyuan Zheng, Joanne Xiu, Shouhao Zhou, Mustafa Khasraw, Priscilla K. Brastianos, Santosh Kesari, Jethro Hu, Jeremy Rudnick, Michael Salacz, David...> ;International Journal of Cancer. 2018 Dec 1
33 citations
Myxoid glioneuronal tumor of the septum pellucidum and lateral ventricle is defined by a recurrent PDGFRA p.K385 mutation and DNT-like methylation profile
David A. Solomon, Andrey Korshunov, Martin Sill, David T.W. Jones, Marcel Kool, Stefan M. Pfister, Xuemo Fan, Serguei Bannykh, Jethro Hu, Moise Danielpour, Rong Li, Ja...> ;Acta Neuropathologica. 2018 Jul 13
Search for More Effective Chemotherapeutic Regimens for Gliomas: Challenges and Hopes.
Jethro Hu, Santosh Kesari> ;Progress in Neurological Surgery. 2018 Jan 1
21 citations
Report of safety of pulse dosing of lapatinib with temozolomide and radiation therapy for newly-diagnosed glioblastoma in a pilot phase II study.
Andrew Yu, Nadia Faiq, Stacey Green, Albert Lai, Richard M. Green, Jethro Hu, Timothy F. Cloughesy, Ingo K. Mellinghoff, P Leia Nghiemphu> ;Journal of Neuro-Oncology. 2017 Jul 1
10 citations
Planning TTFields treatment using the NovoTAL system-clinical case series beyond the use of MRI contrast enhancement.
Jennifer Connelly, Adilia Hormigo, Nimish Mohilie, Jethro Hu, Aafia Chaudhry, Nicholas Blondin> ;BMC Cancer. 2016 Nov 4
Effects of repetitive transcranial magnetic stimulation on motor recovery and motor cortex excitability in patients with stroke: a randomized controlled trial.
Du J, Tian L, Liu W, Hu J, Xu G, Ma M, Fan X, Ye R, Jiang Y, Yin Q, Zhu W, Xiong Y, Yang F, Liu X> ;Eur. J. Neurol.. 2016-11-01
33 citations
Brainstem Glioma in Adults
Jethro Hu, Stephen Western, Santosh Kesari> ;Frontiers in Oncology. 2016 Aug 9
9 citations
Do Long-Term Survivor Primary Glioblastoma Patients Harbor IDH1 Mutations?
J. Manuel Sarmiento, Debraj Mukherjee, Keith L. Black, Xuemo Fan, Jethro Hu, Miriam A Nuno, Chirag G. Patil> ;Journal of Neurological Surgery. Part A, Central European Neurosurgery. 2016 Mar 2
19 citations
Multi-platform molecular profiling of a large cohort of glioblastomas reveals potential therapeutic strategies
Joanne Xiu, David Piccioni, Tiffany Juarez, Sandeep C. Pingle, Jethro Hu, Jeremy Rudnick, Karen Fink, David Spetzler, Todd Maney, Anatole Ghazalpour, Ryan Bender, Zora...> ;Oncotarget. 2016 Feb 25
Long-term Remission Over Six Years for a Patient with Recurrent Glioblastoma Treated with Cediranib/Lomustine.
Doniel Drazin, Lutfi Al-Khouja, Ashish Patel, Jethro Hu, Surasak Phuphanich> ;Cureus. 2016 Jan 16
50 citations
A phase II study of bevacizumab and erlotinib after radiation and temozolomide in MGMT unmethylated GBM patients
Jeffrey Raizer, Pierre Giglio, Jethro Hu, Morris D. Groves, Ryan Merrell, Charles A. Conrad, Surasak Phuphanich, Vinay K. Puduvalli, Monica Loghin, Nina Paleologos, Yi...> ;Journal of Neuro-Oncology. 2016 Jan 1
6 citations
Isolated Extracranial Intraosseous Metastasis of an Intracranial Meningioma following Bevacizumab Therapy: Case Report and Review of the Literature.
Debraj Mukherjee, Jethro Hu, Ray M Chu> ;Asian Journal of Neurosurgery. 2016 Jan 1
42 citations
Retrospective analysis of the tolerability and activity of lacosamide in patients with brain tumors
Marlon Garzo Saria, Courtney Corle, Jethro Hu, Jeremy Rudnick, Surasak Phuphanich, Maciej M. Mrugala, Laura K. Crew, Daniela A. Bota, Beverly Fu, Ryan Y. Kim, Tiffany ...> ;Journal of Neurosurgery. 2013 Jun 1
19 citations
A phase II trial of oral gimatecan for recurrent glioblastoma
Jethro Hu, Patrick Y. Wen, Lauren E. Abrey, Camilo E. Fadul, Jan Drappatz, Nadia Salem, Jeffrey G. Supko, Fred H. Hochberg> ;Journal of Neuro-Oncology. 2013 Feb 1
21 citations
High levels of phosphorylated MAP kinase are associated with poor survival among patients with glioblastoma during the temozolomide era
Chirag G. Patil, Miriam A Nuno, Adam Elramsisy, Debraj Mukherjee, Christine Carico, Jocelynn Dantis, Jethro Hu, John S. Yu, Xuemo Fan, Keith L. Black, Serguei Bannykh> ;Neuro-Oncology. 2013 Jan 1
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Journal Articles

Myxoid Glioneuronal Tumor of the Septum Pellucidum and Lateral Ventricle Is Defined by a Recurrent PDGFRA p.K385 Mutation and DNT-like Methylation Profile
Melike Pekmezci, Andrew W Bollen, David A Solomon, Xuemo Fan, Serguei Bannykh, James Johnston, Elaine Cham, James P Grenert, Boris C Bastian, Arie Perry, Moise Danielp..., Acta Neuropathologica