JillLouiseOstremMD

Neurology • San Francisco, CA

Movement Disorder

Associate Professor, Neurology, UCSF School of Medicine

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Office
1635 Divisadero St
San Francisco, CA 94115
Phone+1 415-353-2311

Fax+1 415-353-9060
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Education & Training

UCLA David Geffen School of Medicine/UCLA Medical CenterResidency, Neurology, 2000 - 2003
MedStar Health/Georgetown-Washington Hospital CenterInternship, Internal Medicine, 1998 - 1999
George Washington University School of Medicine and Health SciencesClass of 1998

Certifications & Licensure

CA State Medical License 2000 - 2025
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013

Clinical Trials

Deep Brain Stimulation in Patients With Dystonia Start of enrollment: 2008 Jun 01
Completed
Not Applicable
Use of Interventional MRI for Implantation of Deep Brain Stimulator Electrodes Start of enrollment: 2003 Jul 01
Completed
Follow Up Study for Treatment of Parkinson's Disease With Deep Brain Stimulation Start of enrollment: 2010 Jun 01
Completed

Publications & Presentations

PubMed

Extended-release amantadine for OFF-related dystonia in Parkinson's disease.
Alberto J Espay, Jill L Ostrem, Andrea E Formella, Caroline M Tanner> ;Parkinsonism & Related Disorders. 2024 Mar 4
Mapping dysfunctional circuits in the frontal cortex using deep brain stimulation.
Barbara Hollunder, Jill L Ostrem, Ilkem Aysu Sahin, Nanditha Rajamani, Simón Oxenford, Konstantin Butenko, Clemens Neudorfer, Pablo Reinhardt, Patricia Zvarova, Mircea...> ;Nature Neuroscience. 2024 Mar 1
3 citations
Mapping Dysfunctional Circuits in the Frontal Cortex Using Deep Brain Stimulation.
Barbara Hollunder, Jill L Ostrem, Ilkem Aysu Sahin, Nanditha Rajamani, Simón Oxenford, Konstantin Butenko, Clemens Neudorfer, Pablo Reinhardt, Patricia Zvarova, Mircea...> ;Medrxiv. 2023 Aug 25
5 citations
Personalized chronic adaptive deep brain stimulation outperforms conventional stimulation in Parkinson's disease.
Carina R Oehrn, Stephanie Cernera, Lauren H Hammer, Maria Shcherbakova, Jiaang Yao, Amelia Hahn, Sarah Wang, Jill L Ostrem, Simon Little, Philip A Starr> ;Medrxiv. 2023 Aug 8
Parkinsonism of uncertain clinical significance (PUCS): A proposed new diagnostic entity.
Jennifer Zitser, Ethan G Brown, Jill L Ostrem, Caroline M Tanner, James B Rowe, Vy Nguyen, Howie Rosen, Michael D Geschwind, Ian O Bledsoe> ;Journal of the Neurological Sciences. 2023 Aug 15
2 citations
Interactive mobile application for Parkinson's disease deep brain stimulation (MAP DBS): An open-label, multicenter, randomized, controlled clinical trial.
Billnitzer, A., Duffley, G., Szabo, A., Lutz, B., Mahoney-Rafferty, E., Hess, C., Ramirez-Zamora, A., Zeilman, P., Foote, K., Chiu, S., Pourfar, M., Goas Cnp, C., Wood...> ;Parkinsonism & Related Disorders. 2023 Apr 1
4 citations
Targeting Accuracy and Clinical Outcomes of Awake versus Asleep Interventional Magnetic Resonance Imaging-Guided Deep Brain Stimulation for Parkinson's Disease: The Un...
Anthony T Lee, Kasey J Han, Noah Nichols, Vivek R Sudhakar, John F Burke, Thomas A Wozny, Jason E Chung, Monica M Volz, Jill L Ostrem, Alastair J Martin, Paul S Larson...> ;Neurosurgery. 2022 Nov 1
7 citations
Automated deep brain stimulation programming with safety constraints for tremor suppression in patients with Parkinson's disease and essential tremor.
Parisa Sarikhani, Benjamin Ferleger, Kyle Mitchell, Jill Ostrem, Jeffrey Herron, Babak Mahmoudi, Svjetlana Miocinovic> ;Journal of Neural Engineering. 2022 Aug 18
3 citations
Benefits and Risks of a Staged-Bilateral VIM Versus Unilateral VIM DBS for Essential Tremor.
Prarthana Prakash, Guenther Deuschl, Sarah Ozinga, Kyle T Mitchell, Binith Cheeran, Paul S Larson, Aristide Merola, Sergiu Groppa, Tucker Tomlinson, Jill L Ostrem> ;Movement Disorders Clinical Practice. 2022 Aug 1
1 citations
Enhancing Clinical Information Display to Improve Patient Encounters: Human-Centered Design and Evaluation of the Parkinson Disease-BRIDGE Platform.
Ethan G Brown, Erica Schleimer, Ian O Bledsoe, William Rowles, Nicolette A Miller, Stephan J Sanders, Katherine P Rankin, Jill L Ostrem, Caroline M Tanner, Riley Bove> ;JMIR Human Factors. 2022 May 6
11 citations
Prefrontal Physiomarkers of Anxiety and Depression in Parkinson’s Disease
Coralie de Hemptinne, Witney Chen, Caroline A. Racine, Andreea L. Seritan, Andrew M. Miller, Maria S. Yaroshinsky, Sarah S. Wang, Roee Gilron, Simon Little, Ian O. Ble...> ;Frontiers in Neuroscience. 2021 Oct 21
21 citations
Embedded adaptive deep brain stimulation for cervical dystonia controlled by motor cortex theta oscillations.
Vinith Johnson, Robert Wilt, Roee Gilron, Juan Anso, Randy Perrone, Martijn Beudel, Dan Piña-Fuentes, Jeremy Saal, Jill L. Ostrem, Ian O. Bledsoe, Philip A. Starr, Sim...> ;Experimental Neurology. 2021 Nov 1
6 citations
Elevated Mood States in Patients With Parkinson's Disease Treated With Deep Brain Stimulation: Diagnosis and Management Strategies.
Andreea L. Seritan, Lauren L. Spiegel, Jessica Weinstein, Caroline A. Racine, Ethan G. Brown, M.M. Volz, Coralie de Hemptinne, Philip A. Starr, Jill L. Ostrem> ;The Journal of Neuropsychiatry and Clinical Neurosciences. 2021 Jul 2
125 citations
Long-term wireless streaming of neural recordings for circuit discovery and adaptive stimulation in individuals with Parkinson's disease.
Roee Gilron, Simon Little, Randy Perrone, Robert Wilt, Coralie de Hemptinne, Maria S. Yaroshinsky, Caroline A. Racine, Sarah S. Wang, Jill L. Ostrem, Paul S. Larson, D...> ;Nature Biotechnology. 2021 May 3
Moving From Wired to Wireless Brain Stimulation to Treat Movement Disorders: Are We Breaking Ground?
Aparna Wagle Shukla, Jill L. Ostrem, Erin Patrick> ;Movement Disorders. 2021 Feb 6
17 citations
Eight cylindrical contact lead recordings in the subthalamic region localize beta oscillations source to the dorsal STN.
Idit Tamir, Doris D. Wang, Witney Chen, Jill L. Ostrem, Philip A. Starr, Coralie de Hemptinne> ;Neurobiology of Disease. 2020 Dec 1
11 citations
Thalamic deep brain stimulation for acquired dystonia in children and young adults: a phase 1 clinical trial.
Marta San Luciano, Amy Robichaux-Viehoever, Kristen A. Dodenhoff, Melissa L Gittings, Aaron C Viser, Caroline A. Racine, Ian O. Bledsoe, Christa Watson Pereira, Sarah ...> ;Journal of Neurosurgery. Pediatrics. 2021 Feb 1
1 citations
Treatment of Post-Hypoxic Myoclonus using Pallidal Deep Brain Stimulation Placed Using Interventional MRI Methods
Fay Gao, Jill L. Ostrem, Doris D. Wang> ;Tremor and Other Hyperkinetic Movements. 2020 Oct 13
1 citations
Therapeutic Advances in Movement Disorders.
Caroline M. Tanner, Jill L. Ostrem> ;Neurotherapeutics. 2020 Oct 1
7 citations
Letter: Evaluation and Surgical Treatment of Functional Neurosurgery Patients With Implanted Deep Brain Stimulation and Vagus Nerve Stimulation Pulse Generators During...
Robert E. Gross, Cathrin M. Buetefisch, Svjetlana Miocinovic, Katie L Bullinger, Michael S. Okun, Jill L. Ostrem, Kelly D. Foote, Phillip A Starr> ;Neurosurgery. 2020 Aug 1
8 citations
Secondary Worsening Following DYT1 Dystonia Deep Brain Stimulation: A Multi-country Cohort
Takashi Tsuboi, Laura Cif, Philippe Coubes, Jill L. Ostrem, Danilo A. Romero, Yasushi Miyagi, Andres M. Lozano, Philippe De Vloo, Ihtsham Haq, Fangang Meng, Nutan Shar...> ;Frontiers in Human Neuroscience. 2020 Jun 25
39 citations
Structural connectivity predicts clinical outcomes of deep brain stimulation for Tourette syndrome
Kara A. Johnson, Gordon Duffley, Daria Nesterovich Anderson, Jill L. Ostrem, Marie-Laure Welter, Juan Carlos Baldermann, Jens Kuhn, Daniel Huys, Veerle Visser-Vandewal...> ;Brain. 2020 Aug 1
68 citations
Subthalamic nucleus deep brain stimulation with a multiple independent constant current-controlled device in Parkinson's disease (INTREPID): a multicentre, double-blin...
Jerrold L. Vitek, Roshini Jain, Lilly Chen, Alexander I. Tröster, Lauren E. Schrock, Paul A. House, Monique Giroux, Adam O Hebb, Sierra Farris, Donald Whiting, Timothy...> ;The Lancet. Neurology. 2020 Jun 1
25 citations
FDA Approvals and Consensus Guidelines for Botulinum Toxins in the Treatment of Dystonia.
Lauren L. Spiegel, Jill L. Ostrem, Ian O. Bledsoe> ;Toxins. 2020 May 17
1 citations
Phenomenology and Management of Subthalamic Stimulation‐Induced Dyskinesia in Patients With Isolated Dystonia
Ian O. Bledsoe, Kristen A. Dodenhoff, Marta San Luciano, Monica Volz, Philip A. Starr, Leslie C. Markun, Jill L. Ostrem> ;Movement Disorders Clinical Practice. 2020 Apr 22
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Journal Articles

Cortical Potentials Evoked by Subthalamic Stimulation Demonstrate a Short Latency Hyperdirect Pathway in Humans
Jon T Willie, Philip A Starr, Jill L Ostrem, Svjetlana Miocinovic, The Journal of Neuroscience

Press Mentions

Acurex Biosciences to Present Early Clinical Results Supporting Its Novel Parkinson’s Disease Biomarkers at a Michael J. Fox Foundation Biomarkers WorkshopMay 15th, 2023
Boston Scientific : Receives FDA Approval for Next-Generation Image Guided Programming Software for Deep Brain Stimulation TherapyApril 14th, 2022
FDA Approves Advanced Image Guided Software Program for DBSApril 14th, 2022
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