JiongShiMD

Neurology • Phoenix, AZ

Neurologist Barrow Neurological Institute · Phoenix, AZ

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Office
240 W Thomas Rd
Ste 301
Phoenix, AZ 85013
Phone+1 602-406-6262

Fax+1 602-406-6260
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Education & Training

Case Western Reserve University/University Hospitals Cleveland Medical CenterResidency, Neurology, 2001 - 2004
Shanghai Medical UniversityClass of 1993

Certifications & Licensure

AZ State Medical License 2004 - 2025
NV State Medical License 2020 - 2023
OH State Medical License 2000 - 2018
American Board of Psychiatry and Neurology Neurology

Clinical Trials

Nuedexta in the Treatment of Pseudobulbar Affect in Patients With Alzheimer's Disease Start of enrollment: 2012 Aug 28
Terminated
Phase 4
Progress of Mild Alzheimer's Disease in Participants on Solanezumab Versus Placebo Start of enrollment: 2013 Jul 01
Terminated
Phase 3

Publications & Presentations

PubMed

Vascular dementia has the highest hospitalisation rate in China: a nationwide hospital information system study.
Yue Wang, Shiping Li, Qi Zhou, Yongjun Wang, Jiong Shi> ;Stroke and Vascular Neurology. 2023 Feb 1
19 citations
The Cause of Alzheimer's Disease: The Theory of Multipathology Convergence to Chronic Neuronal Stress.
Boris Decourt, Gary X D'Souza, Jiong Shi, Aaron Ritter, Jasmin Suazo, Marwan N Sabbagh> ;Aging and Disease. 2022 Feb 1
9 citations
Alzheimer's disease diagnosis and management: Perspectives from around the world.
Diana Kerwin, Carla Abdelnour, Paulo Caramelli, Adesola Ogunniyi, Jiong Shi, Henrik Zetterberg, Martin Traber> ;Alzheimer's & Dementia. 2022 Jan 1
8 citations
Review of Advanced Drug Trials Focusing on the Reduction of Brain Beta-Amyloid to Prevent and Treat Dementia.
Boris Decourt, Keith Noorda, Kevin Noorda, Jiong Shi, Marwan N Sabbagh> ;Journal of Experimental Pharmacology. 2022 Jan 1
48 citations
Critical Appraisal of Amyloid Lowering Agents in AD.
Boris Decourt, Fadel Boumelhem, Evans D. Pope, Jiong Shi, Zoltan Mari, Marwan N. Sabbagh> ;Current Neurology and Neuroscience Reports. 2021 Jun 10
5 citations
Dementia with Lewy bodies: emerging drug targets and therapeutics
Evans D. Pope, Laura Cordes, Jiong Shi, Zoltan Mari, Boris Decourt, Marwan N. Sabbagh> ;Expert Opinion on Investigational Drugs. 2021 Apr 26
4 citations
Does Informant-Based Reporting of Cognitive Decline Correlate with Age-Adjusted Hippocampal Volume in Mild Cognitive Impairment and Alzheimer's Disease?
Marwan N. Sabbagh, Justin B. Miller, Stephen E. Jones, Aaron Ritter, Jiong Shi, Boris Decourt, Dylan Wint> ;Journal of Alzheimer's Disease Reports. 2021 Mar 11
9 citations
Early loss of cerebellar Purkinje cells in human and a transgenic mouse model of Alzheimer's disease.
Kiran Chaudhari, Linshu Wang, Jonas Kruse, Ali Winters, Nathalie Sumien, Ritu A. Shetty, Jude Prah, Ran Liu, Jiong Shi, Michael J. Forster, Shao-Hua Yang> ;Neurological Research. 2021 Mar 10
3 citations
Therapeutic considerations for APOE and TOMM40 in Alzheimers disease: A tribute to Allen Roses MD
Marwan N. Sabbagh, Evans D. Pope, Laura Cordes, Jiong Shi, Boris Decourt> ;Expert Opinion on Investigational Drugs. 2021 Jan 2
60 citations
Effect of ApoE isoforms on mitochondria in Alzheimer disease.
Junxiang Yin, Eric M. Reiman, Thomas G. Beach, Geidy E. Serrano, Marwan N. Sabbagh, Megan Nielsen, Richard J. Caselli, Jiong Shi> ;Neurology. 2020 Jun 9
24 citations
Apolipoprotein E regulates mitochondrial function through the PGC-1α-sirtuin 3 pathway.
Junxiang Yin, Megan Nielsen, Tanner Carcione, Shiping Li, Jiong Shi> ;Aging. 2019 Dec 6
9 citations
Does Informant-Based Reporting of Cognitive Symptoms Predict Amyloid Positivity on Positron Emission Tomography?
Hannah E. Brunet, Justin B. Miller, Jiong Shi, Briana Chung, Bryce T. Munter, Marwan N. Sabbagh> ;Alzheimer's & Dementia. 2019 Dec 1
23 citations
Ketones improves Apolipoprotein E4-related memory deficiency via sirtuin 3.
Junxiang Yin, Megan Nielsen, Shiping Li, Jiong Shi> ;Aging. 2019 Jul 7
24 citations
Faster Cognitive Decline in Dementia Due to Alzheimer Disease With Clinically Undiagnosed Lewy Body Disease
Michael Malek-Ahmadi, Thomas G. Beach, Edward Zamrini, Charles H. Adler, Marwan N. Sabbagh, Holly A. Shill, Sandra A. Jacobson, Christine Belden, Richard J. Caselli, B...> ;Plos One. 2019 Jun 25
14 citations
Sirtuin 3 promotes microglia migration by upregulating CX3CR1.
Runjing Cao, Shiping Li, Junxiang Yin, Li Guo, Jiong Shi> ;Cell Adhesion & Migration. 2019 Jun 17
11 citations
Functional analysis of the secondary HIV-1 capsid binding site in the host protein cyclophilin A.
Wang Peng, Jiong Shi, Chantal L. Márquez, Derrick Lau, James C. Walsh, K. M. Rifat Faysal, Chang H Byeon, In-Ja L. Byeon, Christopher Aiken, Till Böcking> ;Retrovirology. 2019 Apr 4
3 citations
A prospective study on gait dominant normal pressure hydrocephalus
Melissa Song, Abraham Lieberman, Terry D. Fife, Megan Nielsen, Sharon Hayden, Marwan N. Sabbagh, Jiong Shi> ;Acta Neurologica Scandinavica. 2019 Apr 1
9 citations
Sirtuin 3 Mediates Tau Deacetylation
Shiping Li, Junxiang Yin, Megan Nielsen, Thomas G. Beach, Li Guo, Jiong Shi> ;Journal of Alzheimer's Disease. 2019 Jan 1
18 citations
Sirtuin 3 attenuates amyloid-β induced neuronal hypometabolism
Junxiang Yin, Shiping Li, Megan Nielsen, Tanner Carcione, Winnie S. Liang, Jiong Shi> ;Aging. 2018 Oct 23
54 citations
Salivary beta amyloid protein levels are detectable and differentiate patients with Alzheimer's disease dementia from normal controls: preliminary findings.
Marwan N. Sabbagh, Jiong Shi, Moonhee Lee, Lisa Arnold, Jennifer Heim, Patrick McGeer> ;BMC Neurology. 2018 Sep 26
34 citations
Use of Flutemetamol F 18-Labeled Positron Emission Tomography and Other Biomarkers to Assess Risk of Clinical Progression in Patients With Amnestic Mild Cognitive Impa...
David A. Wolk, Carl H. Sadowsky, Beth Safirstein, Juha O. Rinne, Ranjan Duara, Richard Perry, Marc Agronin, Jose Gamez, Jiong Shi, Adrian Ivanoiu, Lennart Minthon, Zuz...> ;JAMA Neurology. 2018 Sep 1
45 citations
Amyloid-β Increases Tau by Mediating Sirtuin 3 in Alzheimer’s Disease
Junxiang Yin, Pengcheng Han, Melissa Song, Megan Nielsen, Thomas G. Beach, Geidy E. Serrano, Winnie S. Liang, Richard J. Caselli, Jiong Shi> ;Molecular Neurobiology. 2018 Mar 24
2 citations
Downward finger displacement distinguishes Parkinson disease dementia from Alzheimer disease
Abraham Lieberman, Aman Deep, Jiong Shi, Rohit Dhall, Saulena Shafer, Guillermo Moguel-Cobos, Ravneet Dhillon, Christopher W. Frames, Margaret McCauley> ;The International Journal of Neuroscience. 2018 Feb 1
29 citations
Hippocampal synaptic and neural network deficits in young mice carrying the human APOE4 gene.
Guo Zhu Sun, Yong Chang He, Xiao Kuang Ma, Shuang Tao Li, De jie Chen, Ming Gao, Shenfeng Qiu, Jun Xiang Yin, Jiong Shi, Jie Wu> ;CNS Neuroscience & Therapeutics. 2017 Aug 7
42 citations
Increasing Precision of Clinical Diagnosis of Alzheimer's Disease Using a Combined Algorithm Incorporating Clinical and Novel Biomarker Data
Marwan N. Sabbagh, Lih-Fen Lue, Daniel Fayard, Jiong Shi> ;Neurology and Therapy. 2017 Jul 1
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