JoannEMansonMD

Endocrinology • Boston, MA

Diabetes, Lipid Metabolism

Michael and Lee Bell Professor of Women's Health, Brigham and Women's Hospital, Preventative Cardiology

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Office
Brigham & Women's Hosp
900 Commonwealth Ave E.
Boston, MA 02215
Phone+1 617-278-0871
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Education & Training

Boston University Medical CenterFellowship, Endocrinology, Diabetes, and Metabolism, 1982 - 1984
Beth Israel Deaconess Medical CenterResidency, Internal Medicine, 1979 - 1982
Case Western Reserve University School of MedicineClass of 1979

Certifications & Licensure

MA State Medical License 1981 - 2025
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism

Awards, Honors, & Recognition

Elected Member Institute of Medicine, 2011
Whos Who in Medicine and Healthcare Marquis Whos Who
Fellow (FACE) American Association of Clinical Endocrinology

Clinical Trials

Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS) Start of enrollment: 1993 May 01
Completed
Phase 2
Nurses' Health Study (Cardiovascular Component) Start of enrollment: 1980 Aug 01
Active, not recruiting
KEEPS Cognitive and Affective Study Start of enrollment: 2007 May 01
Vitamin D and Omega-3 Trial (VITAL) Start of enrollment: 2010 Jul 01
Active, not recruiting
Phase 3
COcoa Supplement and Multivitamin Outcomes Study for the Mind Start of enrollment: 2016 Sep 01
Completed
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Publications & Presentations

PubMed

27 citations
Association of Cardiovascular Health With Life Expectancy Free of Cardiovascular Disease, Diabetes, Cancer, and Dementia in UK Adults.
Xuan Wang, Hao Ma, Xiang Li, Yoriko Heianza, JoAnn E Manson, Oscar H Franco, Lu Qi> ;JAMA Internal Medicine. 2023 Apr 1
Accelerometer-measured physical activity and postmenopausal breast cancer incidence in the Women's Health Accelerometry Collaboration.
Eric T Hyde, Andrea Z LaCroix, Kelly R Evenson, Annie Green Howard, Blake Anuskiewicz, Chongzhi Di, John Bellettiere, Michael J LaMonte, JoAnn E Manson, Julie E Buring...> ;Cancer. 2023 May 15
4 citations
Investigating Gene-Diet Interactions Impacting the Association Between Macronutrient Intake and Glycemic Traits.
Kenneth E Westerman, Maura E Walker, Sheila M Gaynor, Jennifer Wessel, Daniel DiCorpo, Jiantao Ma, Alvaro Alonso, Stella Aslibekyan, Abigail S Baldridge, Alain G Berto...> ;Diabetes. 2023 May 1
3 citations
Low-Carbohydrate Diet Scores and Mortality Among Adults With Incident Type 2 Diabetes.
Yang Hu, Gang Liu, Edward Yu, Biqi Wang, Clemens Wittenbecher, JoAnn E Manson, Eric B Rimm, Liming Liang, Kathryn Rexrode, Walter C Willett, Frank B Hu, Qi Sun> ;Diabetes Care. 2023 Apr 1
18 citations
Management of Menopausal Symptoms: A Review.
Carolyn J Crandall, Jaya M Mehta, JoAnn E Manson> ;JAMA. 2023 Feb 7
4 citations
Longitudinal patterns of abdominal visceral and subcutaneous adipose tissue, total body composition, and anthropometric measures in postmenopausal women: Results from ...
Hailey R Banack, Jennifer W Bea, Zhao Chen, Robert M Blew, Skye Nicholas, Marcia Stefanick, Robert A Wild, JoAnn E Manson, Andrew O Odegaard> ;International Journal of Obesity. 2023 Apr 1
6 citations
Over-the-counter fish oil supplementation and pro-resolving and pro-inflammatory lipid mediators in rheumatoid arthritis.
Nathalie E Marchand, May Y Choi, Emily G Oakes, Nancy R Cook, Emma Stevens, Natalya Gomelskaya, Gregory Kotler, JoAnn E Manson, Jessica Lasky-Su, Samia Mora, I-Min Lee...> ;Prostaglandins, Leukotrienes, and Essential Fatty Acids. 2023 Mar 1
6 citations
Accelerometer-measured physical activity and sitting with incident mild cognitive impairment or probable dementia among older women.
Steve Nguyen, Andrea Z LaCroix, Kathleen M Hayden, Chongzhi Di, Priya Palta, Marcia L Stefanick, JoAnn E Manson, Stephen R Rapp, Michael J LaMonte, John Bellettiere> ;Alzheimer's & Dementia. 2023 Jul 1
4 citations
Sex Hormone-Binding Globulin and Risk of Coronary Heart Disease in Men and Women.
Jie Li, Lingling Zheng, Kei Hang Katie Chan, Xia Zou, Jihui Zhang, Jundong Liu, Qingwei Zhong, Tracy E Madsen, Wen-Chih Wu, JoAnn E Manson, Xueqing Yu, Simin Liu> ;Clinical Chemistry. 2023 Apr 3
1 citations
Association between urinary phthalate biomarker concentrations and adiposity among postmenopausal women.
Gabriela Vieyra, Susan E Hankinson, Youssef Oulhote, Laura N Vandenberg, Lesley Tinker, JoAnn E Manson, Aladdin H Shadyab, Cynthia A Thomson, Wei Bao, Matthew Allison,...> ;Environmental Research. 2023 Apr 1
4 citations
Association of calcium and vitamin D supplementation with cancer incidence and cause-specific mortality in Black women: Extended follow-up of the Women's Health Initia...
Ikuko Kato, Jun Sun, Theresa A Hastert, Judy Abrams, Joseph C Larson, Wei Bao, Aladdin H Shadyab, Charles Mouton, Lihong Qi, Lisa Warsinger Martin, JoAnn E Manson> ;International Journal of Cancer. 2023 Sep 1
5 citations
Sleep duration, plasma metabolites, and obesity and diabetes: a metabolome-wide association study in US women.
Josef Fritz, Tianyi Huang, Christopher M Depner, Oana A Zeleznik, Elizabeth M Cespedes Feliciano, Wenjun Li, Katie L Stone, JoAnn E Manson, Clary Clish, Tamar Sofer, E...> ;Sleep. 2023 Jan 11
25 citations
Healthy Eating Patterns and Risk of Total and Cause-Specific Mortality.
Zhilei Shan, Fenglei Wang, Yanping Li, Megu Y Baden, Shilpa N Bhupathiraju, Dong D Wang, Qi Sun, Kathryn M Rexrode, Eric B Rimm, Lu Qi, Fred K Tabung, Edward L Giovann...> ;JAMA Internal Medicine. 2023 Feb 1
3 citations
Epigenome-wide meta-analysis of BMI in nine cohorts: Examining the utility of epigenetically predicted BMI.
Whitney L Do, Dianjianyi Sun, Karlijn Meeks, Pierre-Antoine Dugué, Ellen Demerath, Weihua Guan, Shengxu Li, Wei Chen, Roger Milne, Abedowale Adeyemo, Charles Agyemang,...> ;American Journal of Human Genetics. 2023 Feb 2
Rationale and design of an ancillary study evaluating the effects of the cocoa flavanol and/or multivitamin interventions on falls and physical performance outcomes in...
Meryl S LeBoff, Sharon H Chou, Kristin A Ratliff, Nancy R Cook, Allison Clar, Beth Holman, Trisha Copeland, Doug C Smith, Pamela M Rist, JoAnn E Manson, Howard D Sesso...> ;Contemporary Clinical Trials. 2023 Feb 1
16 citations
Association of Body Weight With Response to Vitamin D Supplementation and Metabolism.
Deirdre K Tobias, Heike Luttmann-Gibson, Samia Mora, Jacqueline Danik, Vadim Bubes, Trisha Copeland, Meryl S LeBoff, Nancy R Cook, I-Min Lee, Julie E Buring, JoAnn E M...> ;JAMA Network Open. 2023 Jan 3
10 citations
Adherence to a Healthy Lifestyle in Association With Microvascular Complications Among Adults With Type 2 Diabetes.
Gang Liu, Yanping Li, An Pan, Yang Hu, Siyu Chen, Eric B Rimm, JoAnn E Manson, Meir J Stampfer, Giorgio Giatsidis, Qi Sun, Qian, F.> ;JAMA Network Open. 2023 Jan 3
1 citations
Associations between pituitary-ovarian hormones and cognition in recently menopausal women independent of type of hormone therapy.
Juliana M Kling, N Maritza Dowling, Heather Bimonte-Nelson, Carey E Gleason, Kejal Kantarci, Cynthia M Stonnington, S Mitch Harman, Frederick Naftolin, Lubna Pal, Marc...> ;Maturitas. 2023 Jan 1
Association of adverse pregnancy outcomes and multiple gestation with natural menopause: A population-based cohort study.
Christine R Langton, Brian W Whitcomb, Alexandra C Purdue-Smithe, Quaker E Harmon, Susan E Hankinson, JoAnn E Manson, Bernard A Rosner, Elizabeth R Bertone-Johnson> ;Maturitas. 2023 Jan 1
1 citations
Effects of Vitamin DSupplementation on Cardiovascular and Cancer Outcomes by eGFR in VITAL.
Christine P Limonte, Leila R Zelnick, Andrew N Hoofnagle, Ravi Thadhani, Michal L Melamed, Samia Mora, Nancy R Cook, Heike Luttmann-Gibson, Howard D Sesso, I-Min Lee, ...> ;Kidney360. 2022 Dec 29
2 citations
Chocolate Consumption in Relation to All-Cause and Cause-Specific Mortality in Women: The Women's Health Initiative.
Yangbo Sun, Buyun Liu, Linda G Snetselaar, Robert B Wallace, Aladdin H Shadyab, Guo-Chong Chen, James M Shikany, JoAnn E Manson, Wei Bao> ;Journal of the Academy of Nutrition and Dietetics. 2023 Jun 1
10 citations
Effects of Vitamin Dand Marine Omega-3 Fatty Acids Supplementation on Biomarkers of Systemic Inflammation: 4-Year Findings from the VITAL Randomized Trial.
Yanbin Dong, Haidong Zhu, Li Chen, Ying Huang, William Christen, Nancy R Cook, Trisha Copeland, Samia Mora, Julie E Buring, I-Min Lee, Karen H Costenbader, JoAnn E Manson> ;Nutrients. 2022 Dec 14
4 citations
Long-term aircraft noise exposure and risk of hypertension in postmenopausal women.
Daniel D Nguyen, Eric A Whitsel, Gregory A Wellenius, Jonathan I Levy, Jessica H Leibler, Stephanie T Grady, James D Stewart, Matthew P Fox, Jason M Collins, Melissa N...> ;Environmental Research. 2023 Feb 1
3 citations
Serial 7-Day Electrocardiogram Patch Screening for AF in High-Risk Older Women by the CHARGE-AF Score.
Jeffrey Y Lin, Joseph Larson, Jenny Schoenberg, Alejandra Sepulveda, Lesley Tinker, Matthew Wheeler, Christine Albert, JoAnn E Manson, Gretchen Wells, Lisa W Martin, V...> ;JACC. Clinical Electrophysiology. 2022 Dec 1
2 citations
Breastfeeding duration and subsequent risk of mortality among US women: A prospective cohort study.
Yi-Xin Wang, Mariel Arvizu, Janet W Rich-Edwards, JoAnn E Manson, Liang Wang, Stacey A Missmer, Jorge E Chavarro> ;Eclinicalmedicine. 2022 Dec 1
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Journal Articles

Associations of Menstrual Cycle Characteristics Across the Reproductive Life Span and Lifestyle Factors with Risk of Type 2 Diabetes
Joann Manson, MD, JAMA Network Open
Association of Adverse Pregnancy Outcomes with Risk of Atherosclerotic Cardiovascular Disease in Postmenopausal Women
Mark A Hlatky, Joann E Manson, JAMA Cardiology
Marine N−3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer
Joann E Manson, Samia Mora, Christine M Albert, The New England Journal of Medicine
Habitual Sleep Quality, Plasma Metabolites and Risk of Coronary Heart Disease in Post-Menopausal Women
Susan Redline, Elizabeth M Poole, JoAnn E Manson, Kathryn M Rexrode, International Journal of Epidemiology
Predicting Fracture Risk in Younger Postmenopausal Women: Comparison of the Garvan and FRAX Risk Calculators in the Women’s Health Initiative Study
Erin S LeBlanc, Beatrice J Edwards, Kristine Ensrud, Meryl S LeBoff, Carolyn J Crandall, JoAnn E Manson, Journal of General Internal Medicine
Clinical Research Physical Activity and Incidence of Heart Failure in Postmenopausal Women
Liviu Klein, Karen C Johnson, JoAnn E Manson, Cora E Lewis, ScienceDirect
Using High-Dimensional Machine Learning Methods to Estimate an Anatomical Risk Factor for Alzheimer's Disease Across Imaging Databases
Stephen R Rapp, JoAnn E Manson, ScienceDirect
Menstrual Cycle Characteristics in Adolescence and Early Adulthood Are Associated with Risk of Early Natural Menopause
Brian W Whitcomb, JoAnn E Manson, The Journal of Clinical Endocrinology and Metabolism
Evaluation of the Pooled Cohort Risk Equations for Cardiovascular Risk Prediction in a Multiethnic Cohort from the Women’s Health Initiative
Marian C Limacher, Lisa W Martin, Paul M Ridker, Nancy R Cook, Jennifer G Robinson, Monika M Safford, Nanette K Wenger, Samia Mora, JoAnn E Manson, JAMA
A Transcriptome-Wide Association Study of 229,000 Women Identifies New Candidate Susceptibility Genes for Breast Cancer
JoAnn E Manson, Olufunmilayo I Olopade, Wei Zheng, Nature
Biomarker-Calibrated Total Sugars Intake and Risk of Type 2 Diabetes and Cardiovascular Disease in the Women's Health Initiative Observational Study
JoAnn E Manson, Cynthia A Thomson, American Journal of Epidemiology
Anti-Müllerian Hormone Levels and Incidence of Early Natural Menopause in a Prospective Study
Brian W Whitcomb, Anne Z Steiner, JoAnn E Manson, Human Reproduction
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Lectures

Reproductive Health as a Marker of Subsequent Cardiovascular Disease
93rd Annual Meeting & Expo, Boston, Massachusetts, USA
Reproductive Health as a Marker of Subsequent Cardiovascular Disease
American College of Cardiology, 60th Annual Scientific Session & Expo, New Orleans, Louisiana, USA
Reproductive Health as a Marker of Subsequent Cardiovascular Disease
Endocrine Society, 93rd Annual Meeting & Expo, Boston, Massachusetts, USA
Reproductive Health as a Marker of Subsequent Cardiovascular Disease
60th Annual Scientific Session & Expo, New Orleans, Louisiana, USA
Reproductive Health as a Marker of Subsequent Cardiovascular Disease
American Institute for Cancer Research, Washington, Dist Of Col - 11/3/2011
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Press Mentions

Tests. Body Mass Index Can Affect Vitamin D MetabolismJanuary 24th, 2023
New England Researchers Studying Whether Vitamin D Can Help Prevent COVID-19February 4th, 2021
Too Much of a Good Thing: High Doses of Vitamin D Supplements Linked to Harmful Health EffectsJanuary 13th, 2020
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Grant Support

Risk Factors For CVD In WomenNational Heart, Lung, And Blood Institute1999–2012
Vitamin D And Omega-3 Trial (VITAL)National Cancer Institute2009–2011
The Kronos Early Estrogen Prevention Study (KEEPS)National Center For Research Resources2007–2008
Trial Of Antioxidant Therapy Of CVD In WomenNational Heart, Lung, And Blood Institute1993–2005
Biochemical And Genetic Markers Of Type 2 Diabetes RiskNational Institute Of Diabetes And Digestive And Kidney Diseases2001–2004
Vanguard Center For Women'S Health InitiativeWomen'S Health Initiative - Office Of The Director Nih1993–2000
Biochemical Predictors Of NIDDM In WomenNational Institute Of Diabetes And Digestive And Kidney Diseases1994–1998
Modifiable Determinants Of NIDDMNational Institute Of Diabetes And Digestive And Kidney Diseases1994–1997