Jochen Daniel Muehlschlegel MD MMSc, MBA

PubMed

• Are Anesthesiologists Prepared to Manage Patients With Critical Cardiac Disease?
  Abimbola O Faloye, Beth Ladlie, Jochen D Muehlschlegel, Linda Shore-Lesserson, Christopher A Troianos
  Anesthesia and Analgesia. 2025-03-25
• 1 citations
  Fostering a New Generation of Cardiothoracic Anesthesiology Clinician-Scientists: A Systematic Approach.
  Sergey Karamnov, Ryan Dimentberg, Lauren Cornella, Douglas C Shook, Charles Nyman
  Journal of Cardiothoracic and Vascular Anesthesia. 2024-10-01
• 1 citations
  Atrial fibrillation after cardiac surgery: identifying candidate predictors through a Delphi process.
  Jonathan Bedford, Kara G Fields, Gary Stephen Collins, Gregory Y H Lip, David A Clifton
  BMJ Open. 2024-09-25

Journal Articles

• A new clinical multivariable model that predicts postoperative acute kidney injury: impact of endogenous ouabain  
  Simonini M, Lanzani C, Bignami E, Casamassima N, Frati E, Meroni R, Messaggio E, Alfieri O, Hamlyn J, Body SC, Collard CD, the CABG Genomics Investigators, Zangrillo A..., Nephrol. Dial. Transplant, 1/11/2014
• Surgical treatment of bicuspid aortic valve disease: knowledge gaps and research perspectives  
  Della Corte A, Body SC, Booher AM, Schaefers HJ, Milewski RK, Michelena HI, Evangelista A, Pibarot P, Mathieu P, Limongelli G, Shekar PS, Aranki SF, Ballotta A, Di Ben..., J Thorac Cardiovasc Surg, 1/1/2014
• Common genetic variant for conduction system function at SCN10A modulates SCN5A enhancer activity  
  Van den Boogaard M, Smemo S, Burnicka-Turek O, Arnolds DE, Werken HJG, Klous P, Laat W, McKean D, Muehlschlegel JD, Toka O, Seidman CE, Seidman JG, Christoffels VM, No..., Journal of Clinical Investigation, 1/1/2014
• Epicardial cryoablation resulting in precipitous left ventricular dysfunction  
  Lampert SM, Michaud GF, Couper GS, Muehlschlegel JD, J Thorac Cardiovasc Surg, 1/1/2013
• Roundtable Discussion: Status Asthmaticus in a Patient with an Anterior Mediastinal Mass Seminars  
  Urdaneta F, Muehlschlegel JD, Chawla LS, Palacios M, Janelle GM, Semin Cardiothorac Vasc Anesth, 1/29/2012
• Cardiovascular Alterations in the Parturient Undergoing Cesarean Delivery with Neuraxial Anesthesia Expert Review of Obstetrics & Gynecology  
  Arendt KW, Muehlschlegel JD, Tsen LC, Expert Review of Obstetrics & Gynecology, 1/1/2012
• Polymorphism in the Protease Activated Receptor-4 Gene Region Associates with Platelet Activation and Perioperative Myocardial Injury  
  Muehlschlegel JD, Perry TE, Liu KY, Fox AA, Smith S, Lichtner P, Collard CD, Shernan SK, Hartwig JH, Body SC, Hoffmeister KM, Am J Hematol, 1/2/2011
• Inferring genetic causal effects on survival data with associated endo-phenotypes  
  Lipman PJ, Liu KY, Muehlschlegel JD, Body SC, Lange C, Genetic Epidemiology, 1/1/2011
• Plasma Neutrophil Gelatinase-Associated Lipocalin and Acute Postoperative Kidney Injury in Adult Cardiac Surgical Patients  
  Perry TE, Muehlschlegel JD, Fox AA, Collard CD, Liu KY, Shernan SK, Body SC, Anesth Analg, 1/1/2010
• From Creatine Kinase-MB to Troponin: Do We Really Need to Differentiate between Myocardial Injury and Infarction? Correspondence  
  Muehlschlegel JD, Shernan SK, Body SC, Anesthesiology, 1/1/2010
• Colonic perforation from left ventricular assist device: a rare complication  
  Herman SC, Muehlschlegel JD, Couper GS, Kelly E, Interact Cardiovasc Thorac Surg, 1/1/2010
• Chromosome 9p21 Variant Predicts Mortality after CABG Surgery  
  Muehlschlegel JD, Liu KY, Perry TE, Fox AA, Collard CD, Shernan SK, Body SC, Circulation, 1/1/2010
• Heart-Type Fatty Acid Binding Protein is an Early-Peaking and Independent Predictor of Death after Coronary Artery Bypass Graft Surgery  
  Muehlschlegel JD, Perry TE, Fox AA, Collard CD, Liu KY, Shernan SK, Body SC, Anesth Analg, 1/1/2010
• Preoperative C-reactive Protein Predicts Long-term Mortality and Hospital Length of Stay after Primary, non-emergent Coronary Artery Bypass Grafting  
  Perry TE, Muehlschlegel JD, Liu KY, Fox AA, Collard CD, Body SC, Shernan SK, Anesthesiology, 1/1/2010
• Comparison of the utility of preoperative versus postoperative B-type natriuretic peptide for predicting hospital length of stay or mortality after primary coronary ar...  
  Fox AA, Muehlschlegel JD, Body SC, Shernan SK, Liu KY, Perry TE, Aranki SF, Cook EF, Marcantonio ER, Collard CD, Anesthesiology, 1/1/2010
• Heparin Dose Response is Independent of Preoperative Antithrombin Activity in Patients undergoing Coronary Artery Bypass Graft Surgery  
  Garvin S, Fitzgerald D, Muehlschlegel JD, Perry TE, Fox AA, Shernan SK, Collard CD, Body SC, Anesth Analg, 1/1/2010
• Postoperative Levels, but not Preoperative Levels of Antithrombin are Associated with Major Adverse Cardiac Events after Coronary Artery Bypass Graft Surgery  
  Garvin S, Muehlschlegel JD, Perry TE, Chen J, Liu KY, Fox AA, Collard CD, Aranki SF, Shernan SK, Body SC, Anesth Analg, 1/1/2010
• C-Reactive Protein Gene Variants are Associated with Postoperative C-Reactive Protein Levels after Coronary Artery Bypass Surgery  
  Perry TE, Muehlschlegel JD, Liu KY, Fox AA, Collard CD, Body SC, Shernan SK, BMC Med Genet, 1/8/2009
• Variation in the 4q25 Chromosomal Locus Predicts Atrial Fibrillation after Coronary Artery Bypass Graft Surgery  
  Body S, Collard CD, Shernan SK, Fox AA, Liu KY, Ritchie MD, Perry TE, Muehlschlegel JD, Aranki SF, Donahue BS, Pretorius M, Estrada JC, Ellinor P, Newton-Cheh CH, Seid..., Circulation: Cardiovascular Genetics, 1/1/2009
• Troponin is Superior to ECG and CKMB for Predicting Clinically Significant Myocardial Injury after Coronary Artery Bypass Grafting  
  Muehlschlegel JD, Perry TE, Liu KY, Nascimben L, Fox AA, Collard CD, Avery EG, Aranki SF, D’Ambra M, Shernan SK, Body SC, Eur Heart J, 1/1/2009
• Association of Clinical Research Training Meeting Review  
  Muehlschlegel JD, Clinical Research Perspective, 1/1/2009
• Literature Review  
  Collard CD, Muehlschlegel JD, J Cardiothorac Vase Anesth, 1/22/2008
• Intraoperative Transesophageal Echocardiography Alters The Surgical Course For Patients Undergoing Ascending Aortic Aneurysm Repair  
  Robinson AR, Robinson MS, Martin TD, Muehlschlegel JD, Peng YG, J Cardiothorac Vase Anesth, 1/13/2008
• Treatment of ethanol-induced acute pulmonary hypertension and right ventricular dysfunction in pigs, by sildenafil analogue (UK343-664) or nitroglycerin  
  Sidi A, Naik B, Urdaneta F, Muehlschlegel JD, Kirby DS, Lobato EB, Ann of Card Anaesth, 1/1/2008
• Administration of Milrinone before Ischaemia, in the Presence of Beta Blockade, to Treat Metabolic Impairment and Myocardial Stunning in Pigs  
  Sidi A, Muehlschlegel JD, Kirby DS, Lobato EB, Acta Anaesthesiol Scand, 1/1/2008
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Books/Book Chapters

• A Practical Approach to Transesophageal Echocardiography 
  Chapter: Transesophageal Echocardiography in the Intensive Care Unit 
  Lobato EB, Muehlschlegel JDEditors: Perrino Jr AC, Reeves ST.Lippincott Williams & Wilkins, Philadelphia, PAEdition 2nd,2007
• Complications in Anesthesiology 
  Chapter: Acute Pulmonary Hypertension and Right Ventricular Failure 
  Muehlschlegel JD, Dobija N, Lobato EBEditors: Lobato EB, Gravenstein N.Lippincott Williams & Wilkins, Philadelphia, PAEdition 3rd,2007

Abstracts/Posters

• Pre-operative Risk Score for Post-operative Atrial Fibrillation following Cardiac Surgery
  Asher S, Malzberg G, Shekar P, Kaneko T, Huang CC, McGurk S, Oxley B, Bloom J, Sundt TM, Shahian D, Muehlschlegel JD, Body SC, 38th Annual Meeting of the Society of Cardiovascular Anesthesiologists, Orlando, FL, 1/1/2017
• Preoperative Echocardiographic Grade of Tricuspid Regurgitation Indicates Greater Severity than Intraoperative Grade and is Associated with Long-Term Postoperative Mor...
  Wang H, Huang CC, Luxford J, Butler C, Fox J, Shernan SK, Muehlschlegel JD, 38th Annual Meeting of the Society of Cardiovascular Anesthesiologists, Orlando, FL, 1/1/2017
• Association Between Bicuspid Aortic Valve Morphotype and Regional Dilatation of the Aortic Root and Trunk
  Habchi K, Ashikhmina E, Heydarpour M, Martin P, Montiero Vieira V, Shahram J, Isselbacher E, Sundt T, Shekar P, Muehlschlegel JD, Body SC, Heart Valve Society Scientific Meeting, Monaco, 1/1/2017
• Does The Preoperative Transthoracic Or Transesophageal Echocardiogram Better Predict Mortality After Non-Mitral Valve Cardiac Surgery?
  Asher S, Wang H, Malzberg G, Shekar P, Kaneko T, Shernan S, Muehlschlegel JD, Body SC, Heart Valve Society Scientific Meeting, Monaco, 1/1/2017
• Novel Protective Genes Associated with Aortic Dilation in Bicuspid Aortic Valve Disease
  Heydarpour M, Sigurdsson M, Habchi K, Montiero Vieira V, Kaneko T, Shekar P, Sundt T, Muehlschlegel JD, Body SC, Heart Valve Society Scientific Meeting, Monaco, 1/1/2017
• Long non-coding RNA Profile altered after ischemia in Human Myocardium
  Saddic L, Chang TW, Sigurdsson MI, Heydarpour M, Body SC, Aranki SF, Seidman C, Seidman JG, Stranger B, Raby B, Muehlschlegel JD, 37th Annual Meeting of the Society of Cardiovascular Anesthesiologists, San Diego, CA, 1/1/2016
• Reoperative Surgical Aortic Valve Replacement vs Transcatheter Valve-in-Valve Replacement for Degenerated Bioprosthetic Aortic Valves
  J. I. Ejiofor, M. Yammine, S. McGurk, L. H. Cohn, J. D. Muehlschlegel, P. S. Shekar, P. Shah, T. Kaneko, 52nd Society of Thoracic Surgeons Annual Meeting, Phoenix, AZ, 1/1/2016
• GWAS of Aortic Stenosis (AS) in patients with Bicuspid Aortic Valve (BAV) disease
  Heydarpour M, Monteiro-Vieira V, Habchi K, Sliwa J, Sigurdsson MI, Muehlschlegel JD, Shekar P, Isselbacher E, Sundt T, Body SC, Annual Meeting of the Heart Valve Society, New York, NY, 1/1/2016
• Functional Status and Outcomes Following CABG
  Ko HA, Muehlschlegel JD, Rydingsward JE, Ejiofor JI, Rawn JD, Christopher KB, 37th Annual Meeting of the Society of Cardiovascular Anesthesiologists, San Diego, CA, 1/1/2016
• Right Ventricular Strain Associated with Failure to Separate from Cardiopulmonary Bypass
  Hanson, R, Querejeta-Roca G, Muehlschlegel JD, Fox JA, Varelmann, DJ, 37th Annual Meeting of the Society of Cardiovascular Anesthesiologists, San Diego, CA, 1/1/2016
• Allele-specific Expression in the Human Heart and its Application to Postoperative Atrial Fibrillation and Myocardial Ischemia
  Sigurdsson MI, Saddic L, Heydarpour M, Chang TW, Shekar P, Aranki SF, Couper GS, Shernan SK, Seidman JG, Body SC, Muehlschlegel JD, American Society of Anesthesiologists Annual Meeting, Chicago, IL, 1/1/2016
• Noncoding RNA in the Ischemic Human Heart
  Saddic L, Chang TW, Sigurdsson MI, Heydarpour M, Body SC, Aranki SF, Seidman C, Seidman JG, Stranger B, Raby B, Muehlschlegel JD, American Society of Anesthesiologists Annual Meeting, Chicago, IL, 1/1/2016
• Genome Wide Association with Aortic Dimension in Bicuspid Aortic Valve Disease
  M. Heydarpour, M.I. Sigurdsson, V. Montiero, J.T. Shahram, J.D. Muehlschlegel, T. Kaneko, P.S. Shekar, T.M. Sundt, S.C. Body, American Heart Association Scientific Sessions, New Orleans, LA, 1/1/2016
• Whole Genome RNA Sequencing Analysis of Modified Delnido Versus Whole Blood Cardioplegia in the Human Left Ventricle
  M. Heydarpour, J.I. Ejiofor, M.S. Gilfeather, S.C. Body, S.F. Aranki, J.D. Muehlschlegel, American Heart Association Scientific Sessions, New Orleans, LA, 1/1/2016
• Severity of Tricuspid Regurgitation Associated With Long Term Mortality in a 21,000 Patient Cohort of Cardiac Surgical Patients
  Luxford J, Butler C, Muehlschlegel JD, 36th Annual Meeting of the Society of Cardiovascular Anesthesiologists, Washington DC, 1/1/2015
• Left Atrial Gene Expression and Expression Quantifying Trait Locus Analysis of Patients with Post-Operative Atrial Fibrillation
  Sigurdsson MI, Chang, TW, Muehlschlegel JD, Heydarpour M, Shernan SK, Body SC, American Heart Association Scientific Sessions, Orlando, FL, 1/1/2015
• Response-eQTLs of human left ventricular tissue after ischemia
  Chang TW, Carey V, Aranki SF, Body SC, Seidman CE, Seidman JG, Stranger B, Raby B, Muehlschlegel JD, 64th Annual Meeting of the American Society of Human Genetics, Baltimore, MD, 1/1/2015
• Right Ventricular Strain as a Predictor of One-Year Mortality After Mitral Valve Replacement
  Varelmann DJ, Muehlschlegel JD, Mizuguchi A, Fox JA, American Society of Echocardiography, 1/1/2015
• How Well Do Three Dimensional Echocardiographic Measurements of Mitral Valve Prostheses Correlate with the Manufacturer’s Standard Measurements?
  Song P, Nyman CB, Muehlschlegel JD, Shernan SK, Fox JA, Huang CC, Wang H, Purcell A, Shook DC, 36th Annual Meeting of the Society of Cardiovascular Anesthesiologists, Washington DC, 1/1/2015
• Patterns Of Rheumatic Heart Disease In A Large Cohort Of Rwandan Surgical Patients
  Guthrie C, Swain JD, Sotillo CL, Huang CC, Wilusz K, Mucumbitsi J, Mutesa L, Bolman RM, Nascimben L, Muehlschlegel JD, Zammert M, 36th Annual Meeting of the Society of Cardiovascular Anesthesiologists, Washington DC, 1/1/2015
• Aortic Atheroma Increase the Risk of Long-Term Mortality
  Butler C, Muehlschlegel JD, 36th Annual Meeting of the Society of Cardiovascular Anesthesiologists, Washington DC, 1/1/2015
• Integrated miRNA and mRNA Responses to Acute Human Left Ventricular Ischemia
  Saddic L, Chang TW, Sigurdsson MI, Heydarpour M, Raby B, Shernan SK, Aranki SF, Body SC, Muehlschlegel JD, AHA Scientific Sessions Annual Meeting, Chicago, IL, 1/1/2014
• Heparin Dose Response Variability Affected by Genetic Variants in the Coagulation Pathway: KNG1 Polymorphisms
  Loo TT, Wadhwani Z, Heydarpour M, Collard CD, Shernan SK, Body SC, Muehlschlegel JD, IARS Annual Meeting, Montreal Canada, 1/1/2014
• Genome-Wide Assessment For Genetic Variants Associated With Long-Term Heart Failure After Coronary Artery Bypass Graft Surgery
  Fox AF, Heydarpour M, Body SC, Collard CD, Barnet CS, Shernan SK, Muehlschlegel JD, Seidman JG, Seidman CE, IARS Annual Meeting, Montreal Canada, 1/1/2014
• Epistasis between Genetic Markers associated with Ambulatory and Postoperative Atrial Fibrillation after Cardiac Surgery
  Sigurdsson M, Muehlschlegel JD, Shernan, Body SC, 36th Annual Meeting of the Society of Cardiovascular Anesthesiologists, New Orleans, LA, 1/1/2014
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Lectures

• The Genetics of Cardiovascular Disease 
  Paradise Island, Bahamas - 1/1/2018
• Perspective on Rheumatic Heart Disease, and Paths to Collaborative Research 
  Kigali, Rwanda - 1/3/2017
• FAER New Investigators Panel: New Leaders of Anesthesia Research: Results of FAER Sponsored Research 
  Boston, MA - 1/1/2017
• Prevention and Treatment of Perioperative Atrial Fibrillation. Overview of Work to Date by the SCA Clinical Practice Improvement Sub-Committee Working Group on Atrial ... 
  Orlando, FL - 1/1/2017
• Chips, SNPs and Heat Maps. Demystifying Perioperative Genomics - The Basics I: Measurement and Quantification 
  Orlando, FL - 1/1/2017
• Precision Medicine and Predictive Analytics: Using Data to Improve Patients Outcome in the Perioperative Period 
  Boston, MA - 1/1/2017
• My Journey Examining Genes in the Operating Room – From SNPs to Grants 
  Brigham and Women’s Hospital - 1/1/2017
• Decreasing Ischemic/Reperfusion Injury and Improving Outcomes in the Cardiac Surgery Patient 
  New Orleans, LA - 1/1/2016
• What causes end organ dysfunction in cardiac surgery? Is it the Pump or Sternotomy? 
  San Diego, CA - 1/1/2016
• The Basics of 3D TEE. Which Pretty Pictures Can I Get and What Can I Do With Them? 
  San Diego, CA - 1/1/2016
• Finding Good Mentors and Developing the Mentor/Mentee Relationship 
  New Orleans, LA - 1/1/2016
• Developing as a Physician Scientist 
  New Orleans, LA - 1/1/2016
• Perioperative Atrial Fibrillation 
  New Orleans, LA - 1/1/2016
• TEE Educator- Wet Lab Simulation 
  New Orleans, LA - 1/1/2016
• Does Genetic Variation Contribute to Perioperative Morbidity? 
  UMass Medical School, Worcester, MA - 1/1/2016
• Perioperative Genetics and Pharmacogenomics 
  Tufts Medical Center, Boston, MA - 1/1/2016
• Transcriptional Profiling of the Human Heart 
  Brigham and Women’s Hospital - 1/1/2016
• Demystifying Promotions – From Assistant to Associate Professor 
  1/1/2015
• Response eQTLs in Myocardial Ischemic Injury 
  Broad Institute at MIT, Cambridge, MA - 1/1/2015
• The Basics of 3D TEE. What to Do in the OR, and how to get those pretty pictures 
  San Diego, CA - 1/1/2015
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  San Diego, CA - 1/1/2015
• Genetics of Myocardial Ischemia 
  Universitätsklinikum Essen (AöR), Klinik für Anästhesiologie und Intensivmedizin, Essen, Germany - 1/1/2015
• Do Genes Impact Ischemic Injury? Current knowledge and future opportunities 
  Beth Israel Deaconess Medical Center, Boston, MA - 1/1/2014
• Genetics of Myocardial Injury – Clinical Implications 
  Brigham and Women's Hospital - 1/1/2014
• Humanitarian Cardiac Surgery in Rwanda 
  Boston, MA - 1/1/2014
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Other

• Cardiopulmonary and Metabolic Physiology of Cross Country Skiing Specific Roller Ski Training (Doctoral Thesis) 
  Muehlschlegel JD, Jakob E, Keul J, Berg A, Albert-Ludwigs-University
  Freiburg, Germany - 1/1/2001