JochenSteppanMDDESA, FAHA

PubMed

• Optimization of resting tension for wire myography in male rat pulmonary arteries.
  Choi, R., Narayanan, R., Jandu, S., Savage, W., Kang, S., Wodu, B., Nandakumar, K., Santhanam, L., Steppan, J.> ;Physiological Reports. 2024 Jan 1
• Additional predictors of the lower limit of cerebral autoregulation during cardiac surgery.
  Benjamin Gavish, Allan Gottschalk, Charles W Hogue, Jochen Steppan> ;Journal of Hypertension. 2023 Nov 1
• Neonatal exposure to hypoxia induces early arterial stiffening via activation of lysyl oxidases.
  Jochen Steppan, Kavitha Nandakumar, Huilei Wang, Rosie Jang, Logan Smith, Sara Kang, William Savage, Maria Bauer, Rira Choi, Travis Brady, Bulouere Princess Wodu, Susa...> ;Physiological Reports. 2023 Apr 1
• Meeting Report: First Cardiovascular Outcomes Research in Perioperative Medicine Conference.
  Karsten Bartels, Kimberly Howard-Quijano, Meghan Prin, Shahzad Shaefi, Jochen Steppan, Eric C Sun, Brittney Williams, Amanda A Fox, Judith Namuyonga, Andrew D Shaw, Mo...> ;Anesthesia and Analgesia. 2023 Feb 1
• 3 citations
  Transpulmonary amino acid metabolism in the sugen hypoxia model of pulmonary hypertension.
  Nicolas Philip, Hongyang Pi, Mahin Gadkari, Xin Yun, John Huetsch, Cissy Zhang, Robert Harlan, Aurelie Roux, David Graham, Larissa Shimoda, Anne Le, Scott Visovatti, P...> ;Pulmonary Circulation. 2023 Jan 1
• 2 citations
  Con: It is Not Necessary to Use a Pulmonary Artery Catheter in Cardiac Surgery.
  Sinead M Nyhan, Jochen Steppan> ;Journal of Cardiothoracic and Vascular Anesthesia. 2023 Apr 1
• 1 citations
  Selected Transesophageal Echocardiographic Parameters of Left Ventricular Diastolic Function Predict Length of Stay Following Coronary Artery Bypass Graft-A Prospectiv...
  Samhati Mondal, Nauder Faraday, Wei Dong Gao, Sarabdeep Singh, Sachidanand Hebbar, Kimberly N Hollander, Thomas S Metkus, Lee A Goeddel, Maria Bauer, Brian Bush, Brian...> ;Journal of Clinical Medicine. 2022 Jul 8
• 1 citations
  Editorial: Cardiovascular Remodeling in Aging and Disease.
  Jochen Steppan, Daniel Nyhan, Lakshmi Santhanam> ;Frontiers in Physiology. 2022 Jan 1
• 1 citations
  Pressure-based estimation of right ventricular ejection fraction: Validation as a clinically relevant target for drug development in a rodent model of pulmonary hypert...
  Ahmed Elassal, Jochen Steppan, Sofia Charania, Lakshmi Santhanam, Inderjit Singh, Paul M. Heerdt> ;Journal of Pharmacological and Toxicological Methods. 2021 Nov 1
• 3 citations
  How We Would Treat Our Own Pulmonary Hypertension if We Needed to Undergo Cardiac Surgery
  Natalia Diaz-Rodriguez, Sineád M. Nyhan, Todd M. Kolb, Jochen Steppan> ;Journal of Cardiothoracic and Vascular Anesthesia. 2021 Sep 24
• Author Correction: An in situ activity assay for lysyl oxidases.
  Huilei Wang, Alan Poe, Lydia Pak, Kavitha Nandakumar, Sandeep Jandu, Jochen Steppan, Reik Löser, Lakshmi Santhanam> ;Communications Biology. 2021 Sep 16
• 4 citations
  Fast-Degrading Tissue-Engineered Vascular Grafts Lead to Increased Extracellular Matrix Cross-Linking Enzyme Expression
  Takuma Fukunishi, Chin Siang Ong, Yusheng Jason He, Takahiro Inoue, Huaitao Zhang, Jochen Steppan, Hiroshi Matsushita, Jed Johnson, Lakshmi Santhanam, Narutoshi Hibino> ;Tissue Engineering. Part A. 2021 Aug 18
• 4 citations
  Probing tissue transglutaminase mediated vascular smooth muscle cell aging using a novel transamidation-deficient Tgm2-C277S mouse model
  Huilei Wang, James K. Chen, Sandeep Jandu, Sean Melucci, William J. Savage, Kavitha Nandakumar, Sara K. Kang, Sebastian F. Barreto-Ortiz, Alan Poe, Shivam Rastogi, Mar...> ;Cell Death Discovery. 2021 Jul 29
• 7 citations
  An in situ activity assay for lysyl oxidases.
  Huilei Wang, Alan Poe, Lydia Pak, Kavitha Nandakumar, Sandeep Jandu, Jochen Steppan, Reik Löser, Lakshmi Santhanam> ;Communications Biology. 2021 Jul 5
• 4 citations
  A novel approach to perioperative risk assessment for patients with pulmonary hypertension.
  Hussein J. Hassan, Traci Housten, Aparna Balasubramanian, Catherine E. Simpson, Rachel L. Damico, Stephen C. Mathai, Paul M. Hassoun, Jochen Steppan, Peter J. Leary, T...> ;ERJ Open Research. 2021 Jul 1
• Red blood cell storage duration and peri‐operative outcomes in paediatric cardiac surgery
  Asif Padiyath, Brian D. Lo, Chin Siang Ong, Dheeraj Goswami, Diana Steppan, Steven M. Frank, Jochen Steppan> ;Vox Sanguinis. 2021 Mar 24
• 1 citations
  Anesthetic techniques for patients with pulmonary hypertension undergoing ophthalmologic procedures: A case series.
  Sinead M. Nyhan, Todd M. Kolb, Jochen Steppan> ;Journal of Clinical Anesthesia. 2021 Mar 2
• 1 citations
  Update on Perioperative Pediatric Pulmonary Hypertension Management
  Rajeev Wadia, Meghan Bernier, Natalia M. Diaz-Rodriguez, Dheeraj Goswami, Sinead M. Nyhan, Jochen Steppan> ;Journal of Cardiothoracic and Vascular Anesthesia. 2021 Feb 28
• 4 citations
  Preoperative Assessment and Perioperative Management of the Patient with Pulmonary Vascular Disease
  Jochen Steppan, Paul M. Heerdt> ;Clinics in Chest Medicine. 2021 Jan 8
• 7 citations
  The Use of Bivalirudin in Pediatric Cardiac Surgery and in the Interventional Cardiology Suite
  Dheeraj Goswami, Matthew DiGiusto, Rajeev Wadia, Sean Barnes, Jamie M. Schwartz, Diana Steppan, Kristen Nelson-McMillan, Richard Ringel, Jochen Steppan> ;Journal of Cardiothoracic and Vascular Anesthesia. 2020 Jan 21
• 7 citations
  Restoring Blood Pressure in Hypertensive Mice Fails to Fully Reverse Vascular Stiffness.
  Jochen Steppan, Sandeep Jandu, William J. Savage, Huilei Wang, Sara Kang, Roshini Narayanan, Daniel Nyhan, Lakshmi Santhanam> ;Frontiers in Physiology. 2020 Jul 21
• 11 citations
  Commonly used mouse strains have distinct vascular properties
  Jochen Steppan, Sandeep Jandu, Huilei Wang, Sara Kang, William J. Savage, Roshini Narayanan, Kavitha Nandakumar, Lakshmi Santhanam> ;Hypertension Research. 2020 May 14
• 1 citations
  Perioperative Lung Ultrasound in the Pediatric Intensive Care Unit-Beyond the Vasculature and Parenchyma.
  Diana Steppan, Matthew DiGiusto, Jochen Steppan> ;Journal of Cardiothoracic and Vascular Anesthesia. 2020 Jan 20
• 34 citations
  Lysyl oxidase-like 2 depletion is protective in age-associated vascular stiffening.
  Jochen Steppan, Huilei Wang, Yehudit Bergman, Marcel J. Rauer, Siqi Tan, Sandeep Jandu, Kavitha Nandakumar, Sebastian F. Barreto-Ortiz, Robert N. Cole, Tatiana Boronin...> ;American Journal of Physiology. Heart and Circulatory Physiology. 2019 Apr 19
• 6 citations
  Trends and Updates on Cardiopulmonary Bypass Setup in Pediatric Cardiac Surgery.
  Chin Siang Ong, Rajeev Wadia, Dheeraj Goswami, Jamie M. Schwartz, Larry Wolff, Narutoshi Hibino, Luca A. Vricella, Daniel Nyhan, Viachaslau Barodka, Jochen Steppan> ;Journal of Cardiothoracic and Vascular Anesthesia. 2019 Oct 1
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Journal Articles

• Trends and Recent Updates on Cardiopulmonary Bypass Setup in Pediatric Cardiac Surgery  
  Medikonda R, Ong CS, Wadia R, Goswami D, Schwartz J, Wolff L, Hibinio N, Vricella L, Nyhan D, Barodka V, Steppan J, Cardiothorac Vasc Anesth, 1/9/2019
• Blood transfusion in cardiac surgery: Balancing science and art  
  Goeddel LA, Frank SM, Steppan J, J Cardiothorac Vasc Anesth, 1/31/2018
• Continuous versus bolus furosemide in the critically ill: More Questions than Answers  
  Jung Y, Steppan J, Goeddel LA, J Cardiothorac Vasc Anesth, 1/22/2018
• Focused review of the perioperative care of patients with pulmonary hypertension and proposal of a perioperative pathway for those patients  
  Steppan J, Diaz-Rodriguez N, Barodka VM, Nyhan D, Pullins E, Housten T, Damico RL, Mathai SC, Hassoun PM, Berkowitz DE, Maxwell BG, Kolb TM, Cureus, 1/15/2018
• The relationship between the ambulatory arterial stiffness index and the lower limit of cerebral autoregulation during cardiac surgery  
  Obata Y, Barodka V, Berkowitz DE, Gottschalk A, Hogue CW, Steppan J, ambulatory arterial stiffness index and the lower limit of cerebral autoregulation during cardiac surgery., 1/8/2018
• Ischemic Post-Conditioning and Milrinone  
  Steppan J, Dan Berkowitz DE, Nyhan D, J Cardiothorac Vasc Anesth, 1/2/2018
• Lysl Oxidase-like 2 (LOXL2): A novel target in age associated-vascular stiffening  
  Steppan J, Wang H, Bergman Y, Tan S, Rauer MJ, Nandakumar K, Ortiz SB, Jandu S, Melucci S, Cole RN, Boronina TN, Zhu W, An SS, Berkowitz DE, Santhanam L, Am J Physiol Heart Circ Phy, 1/1/2018
• When your 35-year-old patient has a sternotomy scar: Anesthesia for adult congenital heart disease patients presenting for non-cardiac surgery  
  Cheema A, Ibekwe S, Nyhan D, Steppan J, Int Anesthesiol Clin, 1/1/2018
• Ejection time: influence of hemodynamics and site of measurement in the arterial tree  
  Obata Y, Mizogami M, Singh S, Nyhan D, Berkowitz DE, Steppan J, Barodka V, Hypertens Res, 1/30/2017
• miR-181b regulates vascular stiffness age dependently in part by regulating TGF-Beta signaling  
  Hori D, Dunkerly-Eyring B, Nomura Y, Biswas D, Steppan J, Henao-Mejia J, Adachi H, Santhanam L, Berkowitz DE, Steenbergen C, Flavell RA, Das S, PLoS One, 1/21/2017
• The impact of posture on the cardiac depolarization and repolarization phases of the QT interval in healthy subjects  
  Obata Y, Ruzankin P, Ong QJ, Berkowitz DE, Berger RD, Steppan J, Barodka V, J Electrocardiol, 1/12/2017
• Pilot Study: Estimation of Stroke Volume and Cardiac Output from Pulse Wave Velocity  
  Obata Y, Mizogami M, Nyhan D, Berkowitz DE, Steppan J, Barodka V, PLoS One, 1/1/2017
• Tissue Transglutaminase Modulates Vascular Stiffness and Function through Crosslinking-Dependent and Crosslinking-Independent Functions  
  Steppan J, Bergman Y, Viegas K, Armstrong D, Tan Siqi, Wang Huilei, Melucci S, Hori D, Yong S, Barreto SF, Isak A, Jandu S, Flavahan N, Butlin M, An SS, Avolio A, Berk..., J Am Heart Assoc, 1/1/2017
• Noninvasive Assessment of the Effect of Position and Exercise on Pulse Arrival to Peripheral Vascular Beds in Healthy Volunteers  
  Obata Y, Ong QJ, Magruder JT, Grichkevitch H, Berkowitz DE, Nyhan D, Steppan J, Barodka V, Front Physiol, 1/1/2017
• Opsin 3 and 4 mediate light-induced pulmonary vasorelaxation that is potentiated by G-protein receptor kinase 2 inhibition  
  Barreto OS, Hori D, Nomura Y, Yun X, Jiang H, Yong H, Chen J, Paek S, Pandey D, Sikka G, Bhatta A, Gillard A, Steppan J, Kim JH, Adachi J, Barodka V, Romer L, An SS, S..., Am J Physiol Lung Cell Mol Physiol, 1/1/2017
• Pulse wave travel distance as a novel marker of ventricular-arterial coupling  
  Obata Y, Ruzankin P, Gottschalk A, Nyhan D, Berkowitz DE, Steppan J, Barodka V, Heart and Vessels, 1/1/2017
• A pulse wave velocity based method to assess the mean arterial blood pressure limits of autoregulation in peripheral arteries  
  Tripathi A, Obata Y, Ruzankin P, Askaryar N, Berkowitz DE, Steppan J, Barodka V, Front Phsyiol, 1/1/2017
• Anesthetic Management of Pheochromocytoma Resection in Adults with Single Ventricle Physiology  
  Suffredini G, Diaz-Rodriguez N, Chakravarthy K, Mathur A, Hayanga HK, Frank SM, Ringel RE, Freiberg S, Barodka VM, Steppan J, Cureus, 1/1/2017
• Microbial short chain fatty acid metabolites lower blood pressure via endothelial G-protein coupled receptor 41  
  Natarajan N, Hori D, Flavahan S, Steppan J, Flavahan NA, Berkowitz DE, Plutznik JL, Physiol Genomics, 1/23/2016
• Seeking a blood pressure-independent measure of vascular properties  
  Steppan J, Sikka G, Hori D, Nyhan D, Berkowitz DE, Gottschalk A, Barodka V, Hypertens Res, 1/1/2016
• Arginase Inhibition Reverses Endothelial Dysfunction, Pulmonary Hypertension, and Vascular Stiffness in Transgenic Sickle-Cell Mice  
  Steppan J, Tran HT, Bead VR, Oh YJ, Sikka G, Bivalacqua T, Burnett AL, Berkowitz DE, Santhanam L, Anesth Analg, 1/1/2016
• The Effects of Hemodynamic Changes on Pulse Wave Velocity in Cardiothoracic Surgical Patients  
  Obata Y, Mizogami M, Singh S, Nyhan D, Berkowitz DE, Steppan J, Barodka V, Biomed Res Int, 1/1/2016
• Complications of Catheter-Based Electrophysiology Procedures in Adults with Congenital Heart Disease: A National Analysis  
  Maxwell BG, Steppan J, Cheng A, J Cardiothoracic Vasc Anesth, 1/1/2015
• Melanopsin mediates light-dependent relaxation in blood vessels  
  Sikka G, Hussman GP, Pandey D, Cao S, Hori D, Park JT, Steppan J, Kim JH, Barodka V, Myers AC, Santhanam L, Nyhan D, Halushka MK, Koehler RC, Snyder SH, Shimoda LA, Be..., Proc Natl Acad Sci USA, 1/1/2014
• Measuring ascending aortic stiffness in vivo in mice using ultrasound  
  Kuo MM, Barodka V, Abraham TP, Steppan J, Shoukas AA, Butlin M, Avolio A, Berkowitz DE, Santhanam L, J Vis Exp, 1/1/2014
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Books/Book Chapters

• The role of arginase in endothelial dysfunction 
  Chapter: Development of Novel Arginase Inhibitors for Therapy of Endothelial Dysfunction 
  Steppan J, Nyhan D, Berkowitz DEEditors: Rudolf Lucas.Edition 1st,2018
• Sustaining, and Improving a Culture of Safety in Health Care 
  Chapter: Patient Safety Reporting Systems: Sustained Quality Improvement Using a Multidisciplinary Team and �Good Catch� Awards 
  Herzer KR, Mirrer M, Xie Y, Steppan J, Li M, Jung C, Cover R, Doyle PA, Mark LJThe Joint Commission, Joint Commission ResourcesEdition 2nd,2017
• Stoelting�s Anesthesia and Co-Existing Disease 
  Chapter: Congenital Heart Disease 
  Steppan J, Maxwell BEditors: Roberta L Hines and Katherine Marschall.ElsevierEdition 7th,2017
• Anesthesia Unplugged 
  Chapter: The Swan Song 
  Steppan J, Brady MB, Mitter NEditors: Christopher Gallagher.McGraw-Hill ProfessionalEdition 2nd,2012
• The 5-minute anesthesia consult 
  Chapter: Defibrillation 
  Steppan J, Mitter N.Editors: Nina Singh-Radcliff.Wolters Kluwer Health/Lippincott Williams & Wilkins2012
• Geriatric Anesthesia 
  Chapter: Diastolic heart function and the elderly 
  Steppan J, Berkowitz DE, Martinez E, Nyhan DEditors: Frederick E. Sieber.McGraw-Hill ProfessionalEdition 1st,2006
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Lectures

• Why is Pulmonary Hypertension Important in the Preoperative Period 
  Chicago, IL - 1/21/2019
• Perioperative Management Concepts for Adults with Congenital Heart Disease � Keys to Success 
  Chicago, IL - 1/20/2019
• Congenital Heart Disease 
  Johns Hopkins University School of Medicine, Baltimore, MD - 1/1/2019
• Pulmonary Hypertension 
  Johns Hopkins University School of Medicine, Baltimore, MD - 1/1/2019
• Echocardiographic Evaluation of the Right Ventricle 
  Johns Hopkins University School of Medicine, Baltimore, MD - 1/1/2019
• Introduction to, and Anesthetic Management of Congenital Heart Disease 
  Johns Hopkins University School of Medicine, Baltimore, MD - 1/1/2019
• Echocardiographic Evaluation of Adult Congenital Heart Disease 
  Johns Hopkins University School of Medicine, Baltimore, MD - 1/1/2019
• Pediatric Cardiac Anesthesia Orientation 
  Johns Hopkins University, Baltimore, MD - 1/1/2019
• Simulation Boot Camp 
  Johns Hopkins University, Baltimore, MD - 1/1/2019
• Severe Pulmonary Hypertension and Noncardiac Surgery - No Need to be Afraid 
  Chicago, IL - 1/1/2019
• Creating a pathway for patients with complex cardiovascular disease undergoing non-cardiac surgery 
  Philadelphia, PA - 1/15/2018
• Pulmonary Hypertension: A Case Discussion 
  Johns Hopkins University School of Medicine, Baltimore, MD - 1/1/2018
• Perioperative Use of Ultrasound 
  Johns Hopkins University, Baltimore, MD - 1/1/2018
• Anesthetic considerations for adults with congenital heart disease 
  Johns Hopkins University, Baltimore, MD - 1/1/2018
• The Patient with Pulmonary Hypertension for Non-Cardiac Surgery 
  San Diego, CA, 2016; Phoenix, AZ, 2018 - 1/1/2018
• Targeting matrix remodeling in vascular stiffening 
  Johns Hopkins University, Baltimore, MD - 1/1/2018
• EP Lab: Does a Cardiac Anesthesiologist Need to Be Here? - Con 
  Phoenix, AZ - 1/29/2017
• Blue Baby Heart Disease - Treatment and Management Experiences of �Blue Baby� heart disease, cardiomyopathy and cardiac failure 
  Johns Hopkins University, Baltimore, MD - 1/26/2017
• Cardiac Disease and Implications of Ophtalmic Surgery 
  Chicago, IL - 1/23/2017
• Let�s not reinvent the wheel everyday: A programmatic approach to the perioperative management of patients with high risk cardiovascular disease presenting for non-car... 
  Boston, MA - 1/21/2017
• Echocardiographic Evaluation of Ventricular Assist Devices 
  Johns Hopkins University School of Medicine, Baltimore, MD - 1/1/2017
• POCUS lecture: Congenital Heart Disease 
  Johns Hopkins University School of Medicine, Baltimore, MD - 1/1/2017
• Perioperative Management Strategies for Adults with Complex Congenital Heart Disease Presenting for Non-Cardiac Surgery 
  Johns Hopkins University School of Medicine, Baltimore, MD - 1/1/2017
• Anesthetic considerations for children with Tetralogy of Fallot 
  Johns Hopkins University, Baltimore, MD - 1/1/2017
• Anesthetic considerations for children with Aortic Coarctation 
  Johns Hopkins University, Baltimore, MD - 1/1/2017
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Other

• Severe Pulmonary Hypertension and Non-Cardiac Surgery 
  Steppan J, Society of Cardiovascular Anesthesiologists published 40th Annual Meeting and Workshops syllabus
  1/1/2018
• The Patient with Pulmonary Hypertension for Non-Cardiac Surgery 
  Steppan J, Society of Cardiovascular Anesthesiologists, 38th Annual Meeting and Workshops syllabus,
  1/1/2016
• Perioperative Management Strategies for Adults with Congenital Heart Disease Presenting for Non-cardiac Surgery 
  Steppan J, American Society of Anesthesiology Review Course Lecture Syllabus
  1/1/2016
• Lecture 31, Heart Diseases and Anesthesia 1 
  Steppan J, Audio-Digest Anesthesiology, 2nd edition
  www.audio-digest.org
  1/1/2015
• Lecture 32, Heart Diseases and Anesthesia 2 
  Steppan J, Audio-Digest Anesthesiology, 2nd edition
  www.audio-digest.org
  1/1/2015
• Questions and answers cardiac anesthesia section of the anesthesia written board prep site 
  Steppan J, GasQuestions
  1/1/2013
• Heart Rate Variability and Electroencephalographic Changes during Acupuncture 
  Steppan J, Department of Anesthesiology, Ruprecht-Karls University
  Heidelberg, Germany - 1/1/2007
• Episode 59: Pulmonary Hypertension 
  Steppan J, AACRaC: Anesthesia and Critical Care Reviews and Commentary
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