JoeAnthonyWareMD

PubMed

• Validation and determination of taselisib, a β-sparing phosphoinositide 3-kinase (PI3K) inhibitor, in human plasma by LC-MS/MS.
  Ding X, Faber K, Shi Y, McKnight J, Dorshorst D, Ware JA, Dean B> ;J Pharm Biomed Anal. 2016-07-15
• Dimerization of glycoprotein Ibα is not sufficient to induce platelet clearance.
  Liang, X.,Syed, A. K.,Russell, S. R.,Ware, J.,Li, R.> ;J. Thromb. Haemost.. 2015 Dec 15
• A supported liquid extraction-LC-MS/MS method for determination of GDC-0980 (Apitolisib), a dual small-molecule inhibitor of class 1A phosphoinositide 3-kinase and mam...
  Ding X, Li F, McKnight J, Schmidt C, Strooisma K, Shimizu H, Faber K, Ware JA, Dean B> ;J Pharm Biomed Anal. 2014-11-01
• Non-myeloablative conditioning with busulfan before hematopoietic stem cell transplantation leads to phenotypic correction of murine Bernard-Soulier syndrome.
  Kanaji S, Fahs SA, Ware J, Montgomery RR, Shi Q> ;J. Thromb. Haemost.. 2014-10-01
• Specific inhibition of ectodomain shedding of glycoprotein Ibα by targeting its juxtamembrane shedding cleavage site.
  Liang X, Russell SR, Estelle S, Jones LH, Cho S, Kahn ML, Berndt MC, Bunting ST, Ware J, Li R> ;J. Thromb. Haemost.. 2013-12-01
• Response to "Drug interactions produced by proton pump inhibitors: not simply a pH effect".
  Budha NR, Benet LZ, Ware JA> ;Clin. Pharmacol. Ther.. 2013-02-01
• Drug absorption interactions between oral targeted anticancer agents and PPIs: is pH-dependent solubility the Achilles heel of targeted therapy?
  Budha NR, Frymoyer A, Smelick GS, Jin JY, Yago MR, Dresser MJ, Holden SN, Benet LZ, Ware JA> ;Clin. Pharmacol. Ther.. 2012-08-01
• A role for adhesion and degranulation-promoting adapter protein in collagen-induced platelet activation mediated via integrin α(2) β(1).
  Jarvis GE, Bihan D, Hamaia S, Pugh N, Ghevaert CJG, Pearce AC, Hughes CE, Watson SP, Ware J, Rudd CE, Farndale RW> ;J. Thromb. Haemost.. 2012-02-01
• Platelet glycoprotein VI facilitates experimental lung metastasis in syngenic mouse models.
  Jain S, Russell S, Ware J> ;J. Thromb. Haemost.. 2009-10-01
• Drug-drug interactions mediated through P-glycoprotein: clinical relevance and in vitro-in vivo correlation using digoxin as a probe drug.
  Fenner, K.S., Troutman, M.D., Kempshall, S., Cook, J.A., Ware, J.A., Smith, D.A., Lee, C.A.> ;Clin Pharmacol Ther. 2009-02-01
• Evaluation of the physiological significance of botrocetin/ von Willebrand factor in vitro signaling.
  Liu J, Joglekar M, Ware J, Fitzgerald MEC, Lowell CA, Berndt MC, Gartner TK> ;J. Thromb. Haemost.. 2008-11-01
• In vivo relevance for platelet glycoprotein Ibalpha residue Tyr276 in thrombus formation.
  Guerrero JA, Shafirstein G, Russell S, Varughese KI, Kanaji T, Liu J, Gartner TK, Bäumler W, Jarvis GE, Ware J> ;J. Thromb. Haemost.. 2008-04-01
• FcRgamma-chain-dependent alphaIIbeta3 elicited outside-in signaling.
  Liu J, Ware J, Jackson CW, Gartner TK> ;J. Thromb. Haemost.. 2007-02-01
• FcRgamma-chain signals in the absence of glycoprotein VI.
  Liu J, Ware J, Jackson CW, Gartner TK> ;J. Thromb. Haemost.. 2007-01-01
• Distinct antithrombotic consequences of platelet glycoprotein Ibalpha and VI deficiency in a mouse model of arterial thrombosis.
  Konstantinides S, Ware J, Marchese P, Almus-Jacobs F, Loskutoff DJ, Ruggeri ZM> ;J. Thromb. Haemost.. 2006-09-01
• Platelet septin complexes form rings and associate with the microtubular network.
  Martínez C, Corral J, Dent JA, Sesma L, Vicente V, Ware J> ;J. Thromb. Haemost.. 2006-06-01
• 98 citations
  Endothelial Cell Activation in Patients With Decompensated Heart Failure
  Paolo C. Colombo, Javier E. Banchs, Sulejman Celaj, Ashok Talreja, Justine Lachmann, Shailesh Malla, Nicholas B. Dubois, Anthony W. Ashton, Farhana Latif, Ulrich P. Jo...> ;Circulation. 2005 Jan 4
• 89 citations
  Thromboxane A2 Receptor Signaling Inhibits Vascular Endothelial Growth Factor–Induced Endothelial Cell Differentiation and Migration
  Anthony W. Ashton, J. Anthony Ware> ;Circulation Research. 2004 Aug 20
• 38 citations
  Thromboxane A2 Receptor Agonists Antagonize the Proangiogenic Effects of Fibroblast Growth Factor-2. Role of Receptor Internalization, Thrombospondin-1, and αvβ3
  Anthony W. Ashton, Yan Cheng, Armin Helisch, J. Anthony Ware> ;Circulation Research. 2004 Apr 2
• 244 citations
  Therapeutic angiogenesis in cardiovascular disease
  Michael Simons, J. Anthony Ware> ;Nature Reviews. Drug Discovery. 2003 Nov 1
• 34 citations
  Inhibition of Tumor Necrosis Factor α-mediated NFκB Activation and Leukocyte Adhesion, with Enhanced Endothelial Apoptosis, by G Protein-linked Receptor (TP) Ligands
  Anthony W. Ashton, Gabriel M. Ware, Dhananjaya K. Kaul, J. Anthony Ware> ;The Journal of Biological Chemistry. 2003 Apr 4
• 117 citations
  Long-term effects of surgical angiogenic therapy with fibroblast growth factor 2 protein
  Marc Ruel, Roger J. Laham, J. Anthony Parker, Mark J. Post, J. Anthony Ware, Michael Simons, Frank W. Sellke> ;The Journal of Thoracic and Cardiovascular Surgery. 2002 Jul 1
• 68 citations
  Protein Kinase C (PKC) δ Regulates PKCα Activity in a Syndecan-4-dependent Manner
  Masahiro Murakami, Arie Horowitz, Shaoqing Tang, J. Anthony Ware, Michael Simons> ;The Journal of Biological Chemistry. 2002 Jun 7
• 75 citations
  Inhibition of Protein Kinase Cα Prevents Endothelial Cell Migration and Vascular Tube Formation In Vitro and Myocardial Neovascularization In Vivo
  Aihong Wang, Motohiro Nomura, Sybill Patan, J. Anthony Ware> ;Circulation Research. 2002 Mar 22
• 71 citations
  Biopsy coupled to quantitative immunofluorescence: a new method to study the human vascular endothelium
  Paolo C. Colombo, Anthony W. Ashton, Sulejman Celaj, Ashok Talreja, Javier E. Banchs, Nicholas B. Dubois, Massimo Marinaccio, Shailesh Malla, Justine Lachmann, J. Anth...> ;Journal of Applied Physiology. 2002 Mar 1
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