JohannaMargaretSeddonMD

Ophthalmology • Worcester, MA

Retinal Disease, Uveitis

Professor, Ophthalmology, University of Massachusetts Medical School

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Office
University of Massachusetts Medical School
55 Lake Avenue North, S3-119
Worcester, MA 01655
Phone+1 800-219-9157
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Education & Training

Tufts Medical CenterResidency, Ophthalmology, 2019 - 2019
MetroWest Medical CenterInternship, Transitional Year, 2019 - 2019
University of Pittsburgh School of MedicineClass of 2019
Harvard School of Public HealthMS, Epidemiology

Certifications & Licensure

MA State Medical License 2019 - 2025
American Board of Ophthalmology Ophthalmology

Awards, Honors, & Recognition

Lifetime Achievement Award American Academy of Ophthalmology, 2018
Lucien Howe Award 2017
Weisenfeld Award ARVO, 2017
Kreissig Award European Retina Society, 2014
Philip S. Hench Award University of Pittsburgh School of Medicine, 2013
CMS Meaningful Use Stage 1 Certification eClinicalWorks EHR, eClinicalWorks LLC, 2012-2013
Fellow (FAAO) American Academy of Ophthalmology
Research Award of Merit Service d'Ophtalmologie, Hopital Intercommunal de Creteil
The Mildred Weisenfeld Award Association for Research in Vision and Ophthalmology (ARVO)
Gold Fellow Award ARVO
inaugural member of the Retina Hall of Fame
The Lucien Howe Medal Award
Distinguished Alumni Award University of Pittsburgh School of Medicine
The Women in Ophthalmology Honor and Mentoring Awards
The Kreissig Award European Retina, Macular and Vitreous Society
Whos Who in Medicine and Healthcare Marquis Whos Who
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Publications & Presentations

PubMed

Family History of Age-Related Macular Degeneration and Genetics Predict Progression to Advanced Age-Related Macular Degeneration Adjusting for Macular Status, Demograp...
Johanna M Seddon, Dikha De, Bernard Rosner> ;American Journal of Ophthalmology. 2023 Nov 1
1 citations
Rare DysfunctionalGenetic Variants and Progression to Advanced Age-Related Macular Degeneration.
Johanna M Seddon, Bernard Rosner, Dikha De, Tianxiao Huan, Anuja Java, John Atkinson> ;Ophthalmology Science. 2023 Jun 1
Evaluation of Risk Prediction with Hierarchical Data: Dependency Adjusted Confidence Intervals for the AUC.
Camden Bay, Robert J Glynn, Johanna M Seddon, Mei-Ling Ting Lee, Bernard Rosner> ;Stats. 2023 Jun 1
1 citations
Identifying Novel Genes and Variants in Immune and Coagulation Pathways Associated with Macular Degeneration.
Tianxiao Huan, Shun-Yun Cheng, Bo Tian, Claudio Punzo, Haijiang Lin, Mark Daly, Johanna M Seddon> ;Ophthalmology Science. 2023 Mar 1
14 citations
Blue Light Exposure: Ocular Hazards and Prevention-A Narrative Review.
Audrey Cougnard-Gregoire, Bénédicte M J Merle, Tariq Aslam, Johanna M Seddon, Isabelle Aknin, Caroline C W Klaver, Gerhard Garhöfer, Alfredo Garcia Layana, Angelo Mari...> ;Ophthalmology and Therapy. 2023 Apr 1
7 citations
Deep ensemble learning for automated non-advanced AMD classification using optimized retinal layer segmentation and SD-OCT scans.
Mousa Moradi, Yu Chen, Xian Du, Johanna M Seddon> ;Computers in Biology and Medicine. 2023 Mar 1
Risk and protection of different rare protein-coding variants of complement component C4A in age-related macular degeneration.
De, D., Casazza, W., Cheng, S., Punzo, C., Daly, M., Zhou, D., Coss, S., Yu, C., Seddon, J., Atkinson, J.> ;Frontiers in Genetics. 2023 Jan 1
5 citations
Functional analysis of rare genetic variants in complement factor I in advanced age-related macular degeneration.
Anuja Java, Nicola Pozzi, Molly C Schroeder, Zheng Hu, Tianxiao Huan, Johanna M Seddon, John Atkinson> ;Human Molecular Genetics. 2022 Oct 28
A Screening Tool for Self-Evaluation of Risk for Age-Related Macular Degeneration: Validation in a Spanish Population.
Alfredo García-Layana, Maribel López-Gálvez, José García-Arumí, Luis Arias, Alfredo Gea-Sánchez, Juan J Marín-Méndez, Onintza Sayar-Beristain, Germán Sedano-Gil, Tariq...> ;Translational Vision Science & Technology. 2022 Jun 1
2 citations
Exploring Consensus on Preventive Measures and Identification of Patients at Risk of Age-Related Macular Degeneration Using the Delphi Process
Alfredo García-Layana, Gerhard Garhöfer, Tariq Aslam, Rufino Silva, Cécile Delcourt, Caroline C W Klaver, Johanna M. Seddon, Angelo Maria Minnella> ;Journal of Clinical Medicine. 2021 Nov 20
1 citations
Deafness in Australian Cattle Dogs associated to QTL on chromosome 20 in genome-wide association study analyses.
Jennifer M. Seddon, Marina R. S. Fortes, Maria Kelly-Smith, S. F. Sommerlad, Jessica J. Hayward, Louise M. Burmeister, L. De Risio, Cathryn S. Mellersh, Julia Freeman,...> ;Animal Genetics. 2021 Jul 27
3 citations
Increased Risk of Skin Cancer in 1,851 Long-Term Retinoblastoma Survivors.
Ruth A. Kleinerman, Sara J. Schonfeld, David H. Abramson, Jasmine H. Francis, Johanna M. Seddon, Lindsay M. Morton, Margaret A. Tucker> ;The Journal of Investigative Dermatology. 2021 Jun 18
4 citations
Benign Tumors in Long-Term Survivors of Retinoblastoma
Milo van Hoefen Wijsard, Sara J. Schonfeld, Flora E. van Leeuwen, Annette C. Moll, Armida W. M. Fabius, David H. Abramson, Johanna M. Seddon, Jasmine H. Francis, Marga...> ;Cancers. 2021 Apr 8
11 citations
The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade
O. McMahon, Thomas M. Hallam, S. Patel, Claire L. Harris, Anaïs Menny, Wioleta M. Zelek, Rafael Widjajahakim, Anuja Java, Tom Cox, Nikolaos Tzoumas, David H. W. Steel,...> ;Human Molecular Genetics. 2021 Mar 30
14 citations
Long-term risk of subsequent cancer incidence among hereditary and nonhereditary retinoblastoma survivors.
Sara J. Schonfeld, Ruth A. Kleinerman, David H. Abramson, Johanna M. Seddon, Margaret A. Tucker, Lindsay M. Morton> ;British Journal of Cancer. 2021 Jan 21
3 citations
Eye Diseases Direct Interest to Complement Pathway and Macrophages as Regulators of Inflammation in COVID-19.
Martine J. Jager, Johanna M. Seddon> ;Asia-Pacific Journal of Ophthalmology. 2021 Jan 1
16 citations
Rare and Common Genetic Variants, Smoking, and Body Mass Index: Progression and Earlier Age of Developing Advanced Age-Related Macular Degeneration
Johanna M. Seddon, Rafael Widjajahakim, Bernard Rosner> ;Investigative Ophthalmology & Visual Science. 2020 Dec 1
19 citations
Functional Analysis of Rare Genetic Variants in Complement Factor I (CFI) using a Serum-Based Assay in Advanced Age-related Macular Degeneration.
Anuja Java, Peter Baciu, Rafael Widjajahakim, Yun Ju Sung, Jae Yang, David J. Kavanagh, John P. Atkinson, Johanna M. Seddon> ;Translational Vision Science & Technology. 2020 Aug 24
17 citations
Genetic Susceptibility, Diet Quality, and Two-Step Progression in Drusen Size.
Bénédicte M. J. Merle, Bernard Rosner, Johanna M. Seddon> ;Investigative Ophthalmology & Visual Science. 2020 May 11
40 citations
Choriocapillaris dropout in early age-related macular degeneration.
Gerard A. Lutty, D. Scott McLeod, Imran Ahmed Bhutto, Malia Michelle Edwards, Johanna M. Seddon> ;Experimental Eye Research. 2020 Mar 1
13 citations
Bone and Soft‐Tissue Sarcoma Risk in Long‐Term Survivors of Hereditary Retinoblastoma Treated With Radiation
Ruth A. Kleinerman, Sara J. Schonfeld, Byron S. Sigel, Jeannette R. Wong-Siegel, Ethel S. Gilbert, David H. Abramson, Johanna M. Seddon, Margaret A. Tucker, Lindsay M....> ;Journal of Clinical Oncology. 2019 Oct 17
10 citations
Association Between Perifoveal Drusen Burden Determined by OCT and Genetic Risk in Early and Intermediate Age-Related Macular Degeneration.
Johanna M. Seddon, James Dossett, Rafael Widjajahakim, Bernard Rosner> ;Investigative Ophthalmology & Visual Science. 2019 Oct 1
22 citations
Patterns of Cause-Specific Mortality Among 2053 Survivors of Retinoblastoma, 1914-2016.
Ruth A. Kleinerman, Margaret A. Tucker, Byron S. Sigel, David H. Abramson, Johanna M. Seddon, Lindsay M. Morton> ;Journal of the National Cancer Institute. 2019 Sep 1
1 citations
Progress in Automated Deep Learning for Macular Degeneration
Harpal Sandhu, Ayman El-Baz, Johanna M. Seddon> ;JAMA Ophthalmology. 2018 Dec 1
34 citations
Validated Prediction Models for Macular Degeneration Progression and Predictors of Visual Acuity Loss Identify High-Risk Individuals
Johanna M. Seddon, Bernard Rosner> ;American Journal of Ophthalmology. 2019 Feb 1
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Books/Book Chapters

Eat Right for Your Sight
Seddon J et al

Press Mentions

Higher Maternal Lutein Intake Linked to Better Child Behavior: StudyNovember 18th, 2019
Growing Body of Science Supports Cognitive Role for Lutein Across the Lifespan: ExpertNovember 6th, 2019
Eating for Your EyesOctober 1st, 2019
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Grant Support

Etiologic Studies Of Age-Related Macular DegenerationNational Eye Institute2006–2011
Etiologic Studies Of Age-Related Macular DegenerationNational Eye Institute2003–2006
Genetic Epidemiology: Aging And Macular DegenerationNational Eye Institute2000
Etiologic Studies Of Age Related Macular DegenerationNational Eye Institute1996–2000
Genetic Epidemiology--Aging And Macular DegenerationNational Eye Institute1995–1997
Clinical Vision Research Development At MeeiNational Eye Institute1991–1995
Age-Related Eye Disease StudyNational Eye Institute1990–1995
Role Of Diet In Retinal Diseases In EdccsNational Eye Institute1992
Case-Control Study Of Uveal MelanomaNational Eye Institute1985–1988
Pilot Study To Validate Measures--Ultraviolet RadiationNational Cancer Institute1986