JohnFalardeauMD

PubMed

• 9 citations
  The cation channel mucolipin-1 is a bifunctional protein that facilitates membrane remodeling via its serine lipase domain.
  Janice M. LaPlante, John L. Falardeau, Edward M. Brown, Susan A. Slaugenhaupt, Peter M. Vassilev> ;Experimental Cell Research. 2011 Apr 1
• 6 citations
  Role of seminiferous tubular development in determining the FSH versus LH responsiveness to GnRH in early sexual maturation.
  Nelly Pitteloud, Apisadaporn Thambundit, Andrew A. Dwyer, John L. Falardeau, Lacey Plummer, Lisa M. Caronia, Frances J. Hayes, Hang Lee, Paul A. Boepple, William F. Cr...> ;Neuroendocrinology. 2009 Jan 1
• 256 citations
  Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice
  John L. Falardeau, Wilson C. J. Chung, Andrew Beenken, Taneli Raivio, Lacey Plummer, Yisrael Sidis, Elka Jacobson-Dickman, Anna V. Eliseenkova, Jinghong Ma, Andrew A. ...> ;The Journal of Clinical Investigation. 2008 Aug 1
• 237 citations
  Reversal of Idiopathic Hypogonadotropic Hypogonadism
  Taneli Raivio, John L. Falardeau, Andrew A. Dwyer, Richard Quinton, Frances J. Hayes, Virginia A. Hughes, Lindsay W. Cole, Simon H. S. Pearce, Hang Lee, Paul A. Boeppl...> ;The New England Journal of Medicine. 2007 Aug 30
• 107 citations
  Lysosomal exocytosis is impaired in mucolipidosis type IV.
  Janice M. LaPlante, Mei Sun, John L. Falardeau, Daisy Dai, Edward M. Brown, Susan A. Slaugenhaupt, Peter M. Vassilev> ;Molecular Genetics and Metabolism. 2006 Dec 1
• 55 citations
  Coding sequence analysis of GNRHR and GPR54 in patients with congenital and adult-onset forms of hypogonadotropic hypogonadism.
  Felecia Cerrato, Jenna K. Shagoury, Milena Králíčková, Andrew A. Dwyer, John L. Falardeau, Metin Ozata, Guy Van Vliet, Pierre Bouloux, Janet E. Hall, Frances J. Hayes,...> ;European Journal of Endocrinology. 2006 Nov 1
• 126 citations
  Identification and characterization of the single channel function of human mucolipin-1 implicated in mucolipidosis type IV, a disorder affecting the lysosomal pathway.
  Janice M. LaPlante, John L. Falardeau, Mei Sun, Marie Kanazirska, Edward M. Brown, Susan A. Slaugenhaupt, Peter M. Vassilev> ;FEBS Letters. 2002 Dec 4
• 16 citations
  Cloning and characterization of the mouse Mcoln1 gene reveals an alternatively spliced transcript not seen in humans
  John L. Falardeau, John C. Kennedy, James S. Acierno, Mei Sun, Stefanie Stahl, Ehud Goldin, Susan A. Slaugenhaupt> ;BMC Genomics. 2002 Feb 5
• 10 citations
  A physical and transcript map of the MCOLN1 gene region on human chromosome 19p13.3-p13.2.
  James S. Acierno, John C. Kennedy, John L. Falardeau, Maire Leyne, Matthew C. Bromley, Matthew W. Colman, Mei Sun, Catherine Bove, Linda K. Ashworth, Lisa H. Chadwick,...> ;Genomics. 2001 Apr 15
• 327 citations
  Mucolipidosis type IV is caused by mutations in a gene encoding a novel transient receptor potential channel
  Mei Sun, Ehud Goldin, Stefanie Stahl, John L. Falardeau, John C. Kennedy, James S. Acierno, Catherine Bove, Christine R. Kaneski, James W. Nagle, Matthew C. Bromley, M...> ;Human Molecular Genetics. 2000 Oct 12
• Join now to see all