JohnWGoetheMD

Psychiatry • Hartford, CT

Director, Burlingame Center, The Institute of Living/Hartford Hospital

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Office
200 Retreat Avenue
Hartford Hospital Psychiatry Dept
Hartford, CT 06106
Phone+1 860-545-7118
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Education & Training

Tulane UniversityResidency, Psychiatry, 1973 - 1975
Medical University of South CarolinaClass of 1972

Certifications & Licensure

CT State Medical License 1983 - 2025
American Board of Psychiatry and Neurology Psychiatry

Clinical Trials

DNA Diagnostics for Minimizing Metabolic Side-Effects of Antipsychotics Start of enrollment: 2007 Jan 01
Unknown status
Efficacy and Safety Study of NeuroStar TMS Therapy in Patients With Major Depressive Disorder With Postpartum Onset Start of enrollment: 2013 Dec 01
Terminated
Not Applicable
Pharmacogenetic Decision Support IT System for Psychiatric Hospitalization: RCT Start of enrollment: 2014 Mar 01
Active, not recruiting
Not Applicable

Publications & Presentations

PubMed

2 citations
Subanalysis of the CYP-GUIDES Trial: CYP2D6 Functional Stratification and Operational Timeline Selection.
Gualberto Ruaño, Joseph Tortora, Saskia Robinson, Seth Baker, Theodore R. Holford, Andrew Winokur, John W. Goethe> ;Psychiatry Research. 2021 Mar 1
9 citations
Results of the CYP-GUIDES randomized controlled trial: Total cohort and primary endpoints.
Gualberto Ruaño, Saskia Robinson, Theodore R. Holford, Raveen Mehendru, Seth Baker, Joseph Tortora, John W. Goethe> ;Contemporary Clinical Trials. 2020 Feb 1
5 citations
Pharmacogenetic clinical decision support for psychiatric hospitalization: Design of the CYP-GUIDES randomized controlled trial.
Gualberto Ruaño, Theodore R. Holford, Richard L. Seip, John W. Goethe, Raveen Mehendru> ;Contemporary Clinical Trials. 2019 Jun 24
13 citations
Predictors of response to synchronized transcranial magnetic stimulation for major depressive disorder.
Noah S. Philip, Andrew F. Leuchter, Ian A. Cook, Joseph M. Massaro, John W. Goethe, Linda L. Carpenter> ;Depression and Anxiety. 2019 Mar 1
5 citations
Sleep improvements and associations with default mode network functional connectivity following rTMS for generalized anxiety disorder.
Gretchen J. Diefenbach, Liron Rabany, Lauren S. Hallion, David F. Tolin, John W. Goethe, Ralitza Gueorguieva, Luis Zertuche, Michal Assaf> ;Brain Stimulation. 2019 Jan 1
17 citations
Neural functional architecture and modulation during decision making under uncertainty in individuals with generalized anxiety disorder
Michal Assaf, Liron Rabany, Luis Zertuche, Laura B. Bragdon, David F. Tolin, John W. Goethe, Gretchen J. Diefenbach> ;Brain and Behavior. 2018 Jun 21
16 citations
Complex psychotropic polypharmacy in bipolar disorder across varying mood polarities: A prospective cohort study of 2712 inpatients.
Julia C. Golden, John W. Goethe, Stephen B. Woolley> ;Journal of Affective Disorders. 2017 Oct 15
38 citations
Resting-State Functional Connectivity in Generalized Anxiety Disorder and Social Anxiety Disorder: Evidence for a Dimensional Approach.
Liron Rabany, Gretchen J. Diefenbach, Laura B. Bragdon, Brian Pittman, Luis Zertuche, David F. Tolin, John W. Goethe, Michal Assaf> ;Brain Connectivity. 2017 Jun 1
29 citations
Improvements in emotion regulation following repetitive transcranial magnetic stimulation for generalized anxiety disorder
Gretchen J. Diefenbach, Michal Assaf, John W. Goethe, Ralitza Gueorguieva, David F. Tolin> ;Journal of Anxiety Disorders. 2016 Oct 1
55 citations
Repetitive transcranial magnetic stimulation for generalised anxiety disorder: a pilot randomised, double-blind, sham-controlled trial.
Gretchen J. Diefenbach, Laura B. Bragdon, Luis Zertuche, Christopher J. Hyatt, Lauren S. Hallion, David F. Tolin, John W. Goethe, Michal Assaf> ;The British Journal of Psychiatry. 2016 May 19
13 citations
Practical interpretation of CYP2D6 haplotypes: Comparison and integration of automated and expert calling.
Gualberto Ruaño, Mohan Kocherla, James S. Graydon, Theodore R. Holford, Gregory S. Makowski, John W. Goethe> ;Clinica Chimica Acta; International Journal of Clinical Chemistry. 2016 May 1
37 citations
Reduction of Seclusion and Restraint in an Inpatient Psychiatric Setting: A Pilot Study.
Ellen W. Blair, Stephen B. Woolley, Bonnie L. Szarek, Theodore F. Mucha, Olga Dutka, Harold I. Schwartz, Jeff Wisniowski, John W. Goethe> ;The Psychiatric Quarterly. 2017 Mar 1
5 citations
A Case Study of Clinical and Neuroimaging Outcomes Following Repetitive Transcranial Magnetic Stimulation for Hoarding Disorder
Gretchen J. Diefenbach, David F. Tolin, Lauren S. Hallion, Luis Zertuche, Liron Rabany, John W. Goethe, Michal Assaf> ;The American Journal of Psychiatry. 2015 Nov 1
72 citations
Efficacy and Safety of Low-field Synchronized Transcranial Magnetic Stimulation (sTMS) for Treatment of Major Depression
Gilmer, W., Andrew F. Leuchter, Ian A. Cook, David Feifel, John W. Goethe, Mustafa M. Husain, Linda L. Carpenter, Michael E. Thase, Andrew D. Krystal, Noah S. Philip, ...> ;Brain Stimulation. 2015 Jul 1
On naturalistic pharmacogenetic studies: reply from the authors
Richard L. Seip, John W. Goethe, Harold I. Schwartz, Gualberto Ruaño> ;Biomarkers in Medicine. 2013 Nov 22
Famous patients: lessons for medicine.
John W. Goethe, Luisa Chmielecki> ;Connecticut Medicine. 2013 Oct 1
30 citations
Treating anxious depression using repetitive transcranial magnetic stimulation.
Gretchen J. Diefenbach, Laura B. Bragdon, John W. Goethe> ;Journal of Affective Disorders. 2013 Oct 1
33 citations
Length of psychiatric hospitalization is correlated with CYP2D6 functional status in inpatients with major depressive disorder
Gualberto Ruaño, Bonnie L. Szarek, David Villagra, Krystyna Gorowski, Mohan Kocherla, Richard L. Seip, John W. Goethe, Harold I. Schwartz> ;Biomarkers in Medicine. 2013 Jun 4
Reviewing our history: economics, culture and healthcare reform.
John W. Goethe> ;Connecticut Medicine. 2012 Mar 1
3 citations
Validation of candidate genes associated with cardiovascular risk factors in psychiatric patients.
Andreas Windemuth, Jose de Leon, John W. Goethe, Harold I. Schwartz, Stephen B. Woolley, Margaret T. Susce, Mohan Kocherla, Kali Bogaard, Theodore R. Holford, Richard ...> ;Progress in Neuro-Psychopharmacology & Biological Psychiatry. 2012 Mar 30
16 citations
Physiogenomic analysis of CYP450 drug metabolism correlates dyslipidemia with pharmacogenetic functional status in psychiatric patients
Gualberto Ruaño, David Villagra, Bonnie L. Szarek, Andreas Windemuth, Mohan Kocherla, Krystyna Gorowski, Christopher Berrezueta, Harold I. Schwartz, John W. Goethe> ;Biomarkers in Medicine. 2011 Aug 23
26 citations
Novel drug metabolism indices for pharmacogenetic functional status based on combinatory genotyping of CYP2C9, CYP2C19 and CYP2D6 genes
David Villagra, John W. Goethe, Harold I. Schwartz, Bonnie L. Szarek, Mohan Kocherla, Krystyna Gorowski, Andreas Windemuth, Gualberto Ruaño> ;Biomarkers in Medicine. 2011 Aug 23
Health care in crisis: readings for the new year.
John W. Goethe> ;Connecticut Medicine. 2011 Mar 1
18 citations
Hospital patients' perceptions during treatment and early discontinuation of serotonin selective reuptake inhibitor antidepressants.
Stephen B. Woolley, Lisa Fredman, John W. Goethe, Alisa K. Lincoln, Timothy Heeren> ;Journal of Clinical Psychopharmacology. 2010 Dec 1
6 citations
Metabolic Abnormalities in Adult and Geriatric Major Depression With and Without Comorbid Dementia
Karen Blank, Bonnie L. Szarek, John W. Goethe> ;Journal of Clinical Hypertension. 2010 Jun 1
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Journal Articles

Predictors of Response to Synchronized Transcranial Magnetic Stimulation for Major Depressive Disorder
Noah S Philip, Ian A Cook, John W Goethe, Andrew F Leuchter, Depression and Anxiety

Press Mentions

Update on Mood Disorders: Implications for PracticeMay 20th, 2016

Hospital Affiliations

Hartford HospitalHartford, Connecticut