John David Heiss MD

Head, Clinical Unit, Surgical Neurology Branch, NINDS, National Institutes of Health

10 Center DrRm 5D37Bethesda, MD 20892
Phone+1 301-496-2921
Fax+1 301-402-0380

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Education & Training

NIH Clinical Center1991 - 1994
University of Cincinnati Medical Center/College of MedicineResidency, Neurological Surgery, 1980 - 1987
University of Michigan Medical SchoolClass of 1980
University of MichiganB.S., Biomedical Sciences, 1974 - 1977

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Certifications & Licensure

OH State Medical License 1981 - 2028
MD State Medical License 1999 - 2026
American Board of Neurological Surgery Neurological Surgery

Awards, Honors, & Recognition

NIH Director’s Award Niemann-Pick Disease, type C, Therapeutic Development Team, 2013
Excellence in Technology Transfer Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD), 2012
Special Recognition Award, for “exemplary performance while demonstrating significant leadership, skill, and ability in serving as a mentor.” NINDS, 2010

Clinical Trials

Genetic Analysis of the Chiari I Malformation Start of enrollment: 2001 Jun 04
COMPLETED
Study of Brain and Spinal Cord Tumor Growth and Cyst Development in Patients With Von Hippel Lindau Disease Start of enrollment: 2001 Feb 15
ACTIVE_NOT_RECRUITING
Brain Infusion of Muscimol to Treat Epilepsy Start of enrollment: 2000 Jun 23
TERMINATED
PHASE1

Publications & Presentations

PubMed

A Phase 1 Study of Convection-Enhanced Delivery of Intraputaminal AAV2-GDNF in Advanced Parkinson's Disease.
John D Heiss, Debra J Ehrlich, Codrin Lungu, Joseph Y Choi, Gretchen Scott
Movement Disorders. 2026-07-06
Bilateral Putaminal Convection of Adeno-Associated Virus Vector Serotype 2 Glial Cell Line-Derived Neurotrophic Factor Gene Therapy in Parkinson's Disease May Provide ...
Vikas Munjal, Asad S Akhter, Matthew T Rocco, Massimo S Fiandaca, John D Heiss
Neurosurgery. 2026-06-01
Chiari malformation type 0: methodological concerns regarding the null structural finding.
Enver I Bogdanov, John D Heiss, Aisylu T Faizutdinova
Acta Neurochirurgica. 2026-05-30

Journal Articles

“Hidden” bone metatstasis from thyroid carcinoma: a clinical note.
Sioka C, Skarulis MC, Tulloch-Reid MK, Heiss JD, Reynolds JC, Rev Esp Med Nucl Imagen Mol, Published Online July 8, 2013, 1/1/2013
Rapidly progressive monoparesis caused by Chiari malformation type 1 without syringomyelia.
Oishi M, Hayashi Y, Kita D, Fukui I, Shinohara M, Heiss JD, Hamada, J. Surgical Neurology Int, Published Online June 12, 2013, 1/1/2013
Normalization of hindbrain morphology after decompression of Chiari malformation Type 1.
Heiss JD, Suffredini G, Bakhtian KD, Sarntinoranont M, Oldfield EH, J Neurosurg, 1/1/2012

Books/Book Chapters

The Chiari Malformations.
Chapter: Epidemiology of Chiari I Malformation.
Heiss JDEditors: Oakes WJ, Tubbs RS.Springer, New York2013
The Chiari Malformations.
Chapter: Treatment of Chiari I Malformation.
Heiss JD, Oldfield EHEditors: Oakes WJ, Tubbs RS.Springer, New York2013
Nanoneurosurgery.
Chapter: From Nanotechnology to Nanoneuroscience/Nanoneurosurgery and Nanobioelectronics: A Historical Review of Milestones.
Yamamoto V, Suffredini G, Nikzad S, Hoenk ME, Boer MS, Teo C, Heiss JD, Kateb BEditors: Kateb B, Heiss JD.Taylor & Francis, New York2013

Abstracts/Posters

A Method to Record, Store, and Analyze Multiple Physiologic Pressure Recordings.
Sansur C, Eidsath A, DeVroom H, Heiss JD, The 14th IEEE Symposium on Computer-Based Medical Systems, Bethesda, MD, 7/1/2001

Lectures

Which Patients with Chiari Malformation
7/1/2013
Pathophysiology of Syringomyelia, International Guest Speaker,
Kazan, Tartar Republic, Russia - 6/1/2013
AAV2-GDNF Clinical Trial for Parkinson’s Disease.
NINDS, NIH - 6/1/2013