JohnDuaneIsaacsJr.MD

PubMed

• 15 citations
  Clinical trials of biosimilars should become more similar
  Jonathan Kay, John D. Isaacs> ;Annals of the Rheumatic Diseases. 2017 Jan 1
• 7 citations
  Patient and researcher perspectives on facilitating patient and public involvement in rheumatology research.
  Judith Pollock, Karim Raza, Arthur G. Pratt, Helen Hanson, Stefan Siebert, Andrew Filer, John D. Isaacs, Christopher D. Buckley, Iain B. McInnes, Marie Falahee> ;Musculoskeletal Care. 2017 Dec 1
• 8 citations
  Let’s not fool ourselves. In RA, the ACR/EULAR remission criteria are not perfect!
  Kenneth F Baker, Arthur G. Pratt, Ben Thompson, John D. Isaacs> ;Annals of the Rheumatic Diseases. 2017 Jun 1
• 16 citations
  Proximal Tubal Patency Demonstrated Through Air Infusion During Flexible Office Hysteroscopy Is Predictive of Whole Tubal Patency
  J. Preston Parry, Daniel M. Riche, Justin Aldred, John D. Isaacs, Elizabeth Lutz, Vicki Butler, James M. Shwayder> ;Journal of Minimally Invasive Gynecology. 2017 May 1
• 43 citations
  High frequency of antidrug antibodies and association of random drug levels with efficacy in certolizumab pegol-treated patients with rheumatoid arthritis: results fro...
  Meghna Jani, John D. Isaacs, Ann W. Morgan, Anthony G. Wilson, Darren Plant, Kimme L. Hyrich, Hector Chinoy, Anne Barton> ;Annals of the Rheumatic Diseases. 2017 Jan 1
• 193 citations
  Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis
  G M Bell, Amy E. Anderson, Julie Diboll, R Reece, O Eltherington, Rachel A. Harry, Tony Fouweather, Claire MacDonald, Thomas Chadwick, Elaine McColl, J. Dunn, Anne M. ...> ;Annals of the Rheumatic Diseases. 2017 Jan 1
• 6 citations
  Achieving consensus on minimum data items (including core outcome domains) for a longitudinal observational cohort study in rheumatoid arthritis.
  Elena Nikiphorou, Sarah L. Mackie, John R. Kirwan, Martin Boers, John D. Isaacs, Ann W. Morgan, Adam Young> ;Rheumatology. 2016 Dec 24
• 20 citations
  Immune reconstitution 20 years after treatment with alemtuzumab in a rheumatoid arthritis cohort: implications for lymphocyte depleting therapies.
  Faye A. H. Cooles, Amy E. Anderson, Tracey Drayton, Rachel A. Harry, Julie Diboll, Lee Munro, Nishanthi Thalayasingham, Andrew J. K. Östör, John D. Isaacs> ;Arthritis Research & Therapy. 2016 Dec 20
• 248 citations
  Mechanism of action of methotrexate in rheumatoid arthritis, and the search for biomarkers
  Philip M Brown, Arthur G. Pratt, John D. Isaacs> ;Nature Reviews. Rheumatology. 2016 Dec 1
• 64 citations
  Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23
  Amanda McGovern, Stefan Schoenfelder, Paul Martin, Jonathan Massey, Kate Duffus, Darren Plant, Annie Yarwood, Arthur G. Pratt, Amy E. Anderson, John D. Isaacs, Julie D...> ;Genome Biology. 2016 Nov 1
• 13 citations
  Detection of anti-drug antibodies using a bridging ELISA compared with radioimmunoassay in adalimumab-treated rheumatoid arthritis patients with random drug levels
  Meghna Jani, John D. Isaacs, Ann W. Morgan, Anthony G. Wilson, Darren Plant, Kimme L. Hyrich, Hector Chinoy, Anne Barton> ;Rheumatology. 2016 Nov 1
• 22 citations
  Components of treatment delay in rheumatoid arthritis differ according to autoantibody status: validation of a single-centre observation using national audit data.
  Arthur G. Pratt, Dennis Lendrem, Ben Hargreaves, Osman Aslam, James Galloway, John D. Isaacs> ;Rheumatology. 2016 Oct 1
• Tolerogenic dendritic cells generated with dexamethasone and vitamin D3 regulate rheumatoid arthritis CD4+ T cells partly via transforming growth factor-β1.
  Anderson AE, Swan DJ, Wong OY, Buck M, Eltherington O, Harry RA, Patterson AM, Pratt AG, Reynolds G, Doran J, Kirby JA, Isaacs JD, Hilkens CMU> ;Clin. Exp. Immunol.. 2016-09-26
• 41 citations
  Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies
  Phillip Lord, Rachel Spiering, Juan Carlos Aguillón, Amy E. Anderson, Silke Appel, Daniel Benitez-Ribas, Anja ten Brinke, Femke Broere, Nathalie Cools, Maria-Cristina ...> ;Peerj. 2016 Aug 30
• 50 citations
  Differential methylation as a biomarker of response to etanercept in patients with rheumatoid arthritis
  Darren Plant, Amy P. Webster, Nisha Nair, James Oliver, Samantha L. Smith, S. Eyre, Kimme L. Hyrich, Anthony G. Wilson, Ann W. Morgan, John D. Isaacs, Jane Worthington...> ;Arthritis & Rheumatology. 2016 Jun 1
• 9 citations
  Previously reported PDE3A-SLCO1C1 genetic variant does not correlate with anti-TNF response in a large UK rheumatoid arthritis cohort.
  Samantha L. Smith, Darren Plant, Xiu Hue Lee, Jonathan Massey, Kimme L. Hyrich, Ann W. Morgan, Anthony G. Wilson, John D. Isaacs, Anne Barton> ;Pharmacogenomics. 2016 May 16
• 69 citations
  Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis
  Gary Reynolds, J R Gibbon, Arthur G. Pratt, Matthew Wood, David Coady, G Raftery, Alice Lorenzi, Andrew Gray, Andrew Filer, Christopher D. Buckley, Muzlifah Haniffa, J...> ;Annals of the Rheumatic Diseases. 2016 May 1
• 3 citations
  Bcl-3 in CD4+ T Cell-Mediated Rheumatoid Arthritis Pathogenesis: Comment on the Article by Meguro et al.
  Arthur G. Pratt, Amy E. Anderson, Ruaidhrí J. Carmody, John D. Isaacs> ;Arthritis & Rheumatology. 2016 Mar 1
• 55 citations
  IL-6-driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anticitrullinated peptide antibody-negative rheumatoid arthritis.
  Amy E. Anderson, Arthur G. Pratt, Mamdouh A.K. Sedhom, John Paul Doran, Christine Routledge, Ben Hargreaves, Philip M. Brown, Kim-Anh Lê Cao, John D. Isaacs, Ranjeny ...> ;Annals of the Rheumatic Diseases. 2016 Feb 1
• 314 citations
  Cytokines in rheumatoid arthritis - shaping the immunological landscape.
  Iain B. McInnes, Christopher D. Buckley, John D. Isaacs> ;Nature Reviews. Rheumatology. 2016 Jan 1
• 128 citations
  A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren's Syndrome
  Katherine James, S Al-Ali, Jessica Tarn, Simon Cockell, Colin S. Gillespie, Victoria Hindmarsh, James Locke, Sheryl Mitchell, Dennis Lendrem, Simon J. Bowman, Elizabet...> ;Plos One. 2015 Dec 22
• 5 citations
  Investigating CD11c expression as a potential genomic biomarker of response to TNF inhibitor biologics in whole blood rheumatoid arthritis samples
  Samantha L. Smith, Stephen Eyre, Annie Yarwood, Kimme L. Hyrich, Ann W. Morgan, Anthony G. Wilson, John D. Isaacs, Darren Plant, Anne Barton> ;Arthritis Research & Therapy. 2015 Dec 14
• 3 citations
  Decade in review-clinical rheumatology: 10 years of therapeutic advances in the rheumatic diseases.
  John D. Isaacs> ;Nature Reviews. Rheumatology. 2015 Nov 1
• 81 citations
  Clinical utility of random anti-tumor necrosis factor drug-level testing and measurement of antidrug antibodies on the long-term treatment response in rheumatoid arthr...
  Meghna Jani, Hector Chinoy, Richard B. Warren, Christopher E.M. Griffiths, Darren Plant, Bo Fu, Ann W. Morgan, Anthony G. Wilson, John D. Isaacs, KimmeL. Hyrich, Anne ...> ;Arthritis & Rheumatology. 2015 May 1
• 11 citations
  Rheumatoid Arthritis: An Evolutionary Force in Biologics
  Philip M Brown, John D. Isaacs> ;Current Pharmaceutical Design. 2015 May 1
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