
John Lynn Jefferies MD MBA, MPH, FACC, FAHA, FHFSA, FRCPE
Heart Failure & Transplantation, Cardiovascular Disease Genetics
Chair, Cardiovascular Institute, University of Tennessee Health Science Center
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107 Meco LnOak Ridge, TN 37830
Phone+1 713-494-5013
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Summary
- Dr. John Jefferies is a cardiologist in Memphis, TN and is affiliated with University of Tennessee Health Science Center, Methodist Le Bonheur Healthcare system, and St Jude Children's Research Hospital. He received his medical degree from University of Tennessee College of Medicine and has been in practice 21 years. He specializes in heritable cardiovascular disease and is experienced in transplant cardiology, adult congenital heart disease, congestive heart failure, critical care medicine, and pediatric cardiology.
Education & Training
Baylor College of MedicineFellowship, Cardiovascular Disease, 2001 - 2006
University of Kentucky College of MedicineResidency, Internal Medicine/Pediatrics, 1996 - 2000
University of Tennessee Health Science Center College of MedicineClass of 1996
University of Tennessee Institute of AgricultureBS, Microbiology, 1988 - 1992
University of KentuckyMPH
Certifications & Licensure
TN State Medical License 2018 - 2028
KY State Medical License 1997 - 2027
TX State Medical License 2003 - 2024
MS State Medical License 2018 - 2023
OH State Medical License 2010 - 2022
MN State Medical License 2016 - 2019
Awards, Honors, & Recognition
- Top Doctors Cincy Magazine, 2014
- Best Doctors in America 2013
- Cincinnati�s Top Doctors 2012
Clinical Trials
- The Cardiovascular Genetic and Therapeutic Implications of Muscular Dystrophy
- Ruboxistaurin in New York Heart Failure Classification III-IV Patients Start of enrollment: 2017 Jun 28
- Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Heterozygous Familial Hypercholesterolemia Start of enrollment: 2021 Jan 27
Roles: Principal Investigator
Publications & Presentations
PubMed
- 1 citationsECG-Based Artificial Intelligence for Classifying Left Ventricular Dysfunction and Heart Failure With Preserved Ejection Fraction.Ibrahim Karabayir, Olivia Gilbert, Ali Valika, Turgay Celik, Arunkumar Krishnan
Journal of the American Heart Association. 2026-08-04 - Relationship of red blood cell mass profiles and anemia type to outcomes and cardiopulmonary exercise performance in chronic heart failure.Veraprapas Kittipibul, Alexandra Novelli, Dmitry Yaranov, Ashley Swavely, Leonardo F Ferreira
American Heart Journal. 2025-10-01 - 10 citationsSerum Proteins Predict Treatment-Related Cardiomyopathy Among Survivors of Childhood Cancer.Suresh Poudel, Him Shrestha, Yue Pan, Qian Li, Kendrick Li
JACC. Cardiooncology. 2025-01-01
Journal Articles
- Cardiopulmonary Fitness Assessment on Maximal and Submaximal Exercise Testing in Patients with Fabry DiseaseJohn L Jefferies, Clifford Chin, Robert J Hopkin, Adam W Powell, American Journal of Medical Genetics. Part A
- Cardiovascular Findings in a Contemporary Cohort of Patients with 1p36 Deletion SyndromeJohn Jefferies, MD, Journal of Cardiac Failure
- Are Guidelines Merely Suggestions?John Jefferies, MD, JACC: Cardiovascular Imaging
Books/Book Chapters
Abstracts/Posters
- Cardiac biomarkers are associated with death and listing for heart transplantation in pediatric patients with newly diagnosed dilated cardiomyopathy: a multi-center st...Lipshultz SE, Rossano JW, Shi L, Jefferies JL, Colan SD, Pahl E, Everitt M, Webber SA, Canter CE, Towbin JA, Kantor P, Feingold B, Addonizion LJ, Lamour J, Ware S, Lee..., Pediatric Academic Society, Toronto, Ontario, Canada, 1/1/2018
- Revising clinical genetic panel test results for pediatric cardiomyopathy after exome sequencing.Lee T, Ware S, Miller E, Dexheimer P, Sridhar A, Lipshultz SE, Shi L, Wilkinson JD, Towbin JA, Webber S, Rossano JW, Hsu D, Jefferies JL, Lal A, Aronow B, Martin L, Ra..., Pediatric Academic Society, Toronto, Ontario, Canada, 1/1/2018
- Fibrosis and hypertrophy assessed by magnetic resonance imaging (MRI) and serum biomarkers in pediatric hypertrophic cardiomyopathy (HCM). A report from the Pediatric ...Kirmani S, Woodard P, Canter CE, Shi L, Pahl E, Colan SD, Towbin JA, Ballweg J, Webber S, Wilkinson J, Rossano JW, Everitt M, Molina K, Kantor P, Jefferies JL, Feingol..., Pediatric Academic Society, Toronto, Ontario, Canada, 1/1/2018
Authored Content
- Omega-3 Fatty Acid and Vitamin D Supplementation in the Primary Prevention of AFibNovember 2020
- AFib: Time for a Paradigm Shift in ManagementNovember 2020
- Cardiovascular Findings in a Contemporary Cohort of Patients with 1p36 Deletion SyndromeAugust 2018
Press Mentions
Daxor Unveils New FDA-Cleared BVA Analyzer Amid Strong Market Demand and Pivotal Clinical Data at HFSASeptember 30th, 2025
Daxor Announces Duke University Study on Blood Volume Analysis in Heart Failure Published in American Heart JournalMay 14th, 2025
Daxor Corporation Announces New Data on Blood Volume Analysis from Duke and Yale Universities Presented at THT 2025February 19th, 2025
Professional Memberships
- Member
- Fellow
- Fellow
- Member
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